scholarly journals Choroidal Detachment after XEN Gel Stent Implantation

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Carlo Alberto Cutolo ◽  
Letizia Negri ◽  
Sara Olivari ◽  
Francesca Cappelli ◽  
Carlo Enrico Traverso ◽  
...  
Keyword(s):  
Wide Field ◽  
Choroidal Detachment ◽  
Implant Surgery ◽  
Xen Gel Stent ◽  
Logistic Analysis ◽  
The Mean ◽  
The University ◽  
Multivariate Logistic Analysis ◽  
Field Imaging

Background. The purpose of this study is to estimate the incidence of choroidal detachment (CD) after XEN gel stent implant surgery and to evaluate the associated factors. Methods. We reviewed the clinical charts of 126 patients who underwent XEN implantation between March 1, 2016, and December 31, 2018 at the University Eye Clinic of Genoa. Ocular, demographics, and perioperative factor were registered and analysed. Univariate and multivariate logistic analysis were performed to investigate factors associated with CD occurrence. Results. Of the 126 patients, 25 (19.8%) developed a choroidal detachment after XEN gel stent implant surgery. The mean period between surgery and CD detection was 5.84 ± 1.77 days. The mean intraocular pressure (IOP) at the time of CD diagnosis was 6.4 ± 3.1 mmHg. Age (OR = 1.10,p<0.019), early postoperative IOP (OR = 0.70,p<0.001), and number of preoperative IOP-lowering drugs (OR = 5.70,p<0.001) were significantly associated with CD presence. Complete resolution was observed in all the cases. Wide-field imaging and ultrasonography were useful tools to diagnose and follow up CD until resolution. Conclusions. When carefully investigated, CD is a relatively common complication after XEN gel stent implant procedure. Older age, lower postoperative IOP, and higher number of preoperative IOP-lowering drugs were significantly associated with the development of CD.

scholarly journals Correlation between fundus autofluorescence and visual function in patients with cone-rod dystrophy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Satoru Kanda ◽  
Takumi Hara ◽  
Ryosuke Fujino ◽  
Keiko Azuma ◽  
Hirotsugu Soga ◽  
...  
Keyword(s):  
Visual Field ◽  
Significant Relationship ◽  
Fundus Autofluorescence ◽  
Univariate Analysis ◽  
Retrospective Chart Review ◽  
Mean Deviation ◽  
Wide Field ◽  
The Mean ◽  
The Relationship ◽  
Field Imaging

AbstractThis study aimed to investigate the relationship between autofluorescence (AF) signal measured with ultra-wide field imaging and visual functions in patients with cone-rod dystrophy (CORD). A retrospective chart review was performed for CORD patients. We performed the visual field test and fundus autofluorescence (FAF) measurement and visualized retinal structures with optical coherence tomography (OCT) on the same day. Using binarised FAF images, we identified a low FAF area ratio (LFAR: low FAF/30°). Relationships between age and logMAR visual acuity (VA), central retinal thickness (CRT), central choroidal thickness (CCT), mean deviation (MD) value, and LFAR were investigated. Thirty-seven eyes of 21 CORD patients (8 men and 13 women) were enrolled. The mean patient age was 49.8 years. LogMAR VA and MD were 0.52 ± 0.47 and − 17.91 ± 10.59 dB, respectively. There was a significant relationship between logMAR VA and MD (p = 0.001). LogMAR VA significantly correlated with CRT (p = 0.006) but not with other parameters. Conversely, univariate analysis suggested a significant relationship between MD and LFAR (p = 0.001). In the multivariate analysis, LFAR was significantly associated with MD (p = 0.002). In conclusion, it is useful to measure the low FAF area in patients with CORD. The AF measurement reflects the visual field deterioration but not VA in CORD.

scholarly journals Aphakia Correction by Injection of Foldable Intra Ocular Lens in the Anterior Chamber

2013 ◽  
Vol 5 ◽  
pp. OED.S12672
Author(s):  
Kagmeni Giles ◽  
Moukouri Ernest ◽  
Domngang Christelle ◽  
Nguefack-Tsague Georges ◽  
Cheuteu Raoul ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Teaching Hospital ◽  
Case Series ◽  
University Teaching ◽  
Case Series Study ◽  
The Mean ◽  
The University

We assessed the outcomes of the use of anterior chamber foldable lens for unilateral aphakia correction at the University Teaching Hospital of Yaounde. In this retrospective, non-comparative, consecutive case series study, we reviewed the records of patients who underwent an operation for aphakia correction by the means of injection of an angular supported foldable lens between January 2009 and December 2011 in the University Teaching Hospital Yaounde. Student's paired t-test was carried out to compare preoperative and postoperative visual acuity (VA) and intraocular pressure (TOP). P-values less than 0.05 were considered statistically significant. Twenty-one patients were included in the study; twelve were male (57.1%) and nine were female (42.9%). The mean age was 55.38 ± 17.67 years (range 9–75 years). The mean follow-up duration was 5.95 ± 3.14 months (range 2–12 months). The mean logMAR visual acuity was 1.26 ± 0.46 pre-operatively and 0.78 ± 0.57 post-operatively ( P = 0.003). The change in intraocular pressure was not statistically significant. Complications included intraocular hypertension (over 21 mmHg) in 3 patients (14.3%) and macular edema, pupillar ovalization, and retinal detachment in one patient each. The results indicate that injection of an angular support foldable lens in the anterior chamber is a useful technique for the correction of aphakia in eyes without capsular support. More extended follow-up, however, and a larger series of patients are needed to ascertain the effectiveness and safety of this procedure.

Gamma Knife surgery for trigeminal schwannoma

2007 ◽  
Vol 106 (5) ◽  
pp. 839-845 ◽  
Author(s):  
Jason Sheehan ◽  
Chun Po Yen ◽  
Yasser Arkha ◽  
David Schlesinger ◽  
Ladislau Steiner
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Surgery ◽  
Long Term Results ◽  
University Of Virginia ◽  
Trigeminal Schwannoma ◽  
The Mean ◽  
The University ◽  
Lost To Follow Up

Object Trigeminal schwannomas are rare intracranial tumors. In the past, resection and radiation therapy were the mainstays of their treatment. More recently, neurosurgeons have begun to use radiosurgery in the treatment of trigeminal schwannomas because of its successful use in the treatment of vestibular schwannomas. In this article the authors evaluate the radiological and clinical outcomes in a series of patients in whom Gamma Knife surgery (GKS) was used to treat trigeminal schwannomas. Methods Twenty-six patients with trigeminal schwannomas underwent GKS at the University of Virginia Lars Lek-sell Gamma Knife Center between 1989 and 2005. Five of these patients had neurofibromatosis and one patient was lost to follow up. The median tumor volume was 3.96 cm3, and the mean follow-up period was 48.5 months. The median prescription radiation dose was 15 Gy, and the median prescription isodose configuration was 50%. There was clinical improvement in 18 patients (72%), a stable lesion in four patients (16%), and worsening of the disease in three patients (12%). On imaging, the schwannomas shrank in 12 patients (48%), remained stable in 10 patients (40%), and increased in size in three patients (12%). These results were comparable for primary and adjuvant GKSs. No tumor growth following GKS was observed in the patients with neurofibromatosis. Conclusions Gamma Knife surgery affords a favorable risk-to-benefit profile for patients harboring trigeminal schwannomas. Larger studies with open-ended follow-up review will be necessary to determine the long-term results and complications of GKS in the treatment of trigeminal schwannomas.

Nephrosplenic space closure significantly decreases recurrent colic in horses: a retrospective analysis

2019 ◽  
Vol 185 (21) ◽  
pp. 657-657 ◽  
Author(s):  
José Manuel Arévalo Rodríguez ◽  
Sigrid Grulke ◽  
Alexandra Salciccia ◽  
Geoffroy de la Rebière de Pouyade
Keyword(s):  
Medical Records ◽  
Telephone Interview ◽  
Horse Breed ◽  
Surgical Closure ◽  
Total Incidence ◽  
Space Closure ◽  
Chi Squared ◽  
The Mean ◽  
The University

BackgroundNephrosplenic space closure is commonly used to reduce relapse of nephrosplenic space entrapment in cases of left dorsal displacement of the left colon (LDDLC). Nevertheless, studies documenting the effectiveness of this surgery are sparse in the literature. The aim of this study was to analyse clinical data of horses presented for LDDLC and evaluate the effect of nephrosplenic space closure on the incidence of colic recurrence.MethodsMedical records of 156 horses diagnosed with LDDLC at the Equine Clinic of the University of Liège between 2004 and 2016 were retrieved for analysis. Extracted data included horse breed, sex, age and weight, initial treatment, and if a subsequent preventive surgical closure of the nephrosplenic space was carried out or not. Follow-up information was obtained by telephone interview. Statistical analyses were performed using a chi-squared test with significance set at P<0.05.ResultsFollow-up data were available for 65 per cent of horses. The mean follow-up was 35 months. There was a significant decrease in the total incidence of colic after closure surgery compared with non-operated horses. No horse was diagnosed with LDDLC after closure of the nephrosplenic space.ConclusionClosure of the nephrosplenic space significantly decreases recurrent colic in horses compared with non-operated horses.

scholarly journals An Ex-Press implant versus trabeculectomy in a fibrotic bleb with late failure after previous trabeculectomy

2021 ◽  
Vol 14 (3) ◽  
pp. 383-387
Author(s):  
Faried Wagdy ◽  
◽  
Hisham Elsorogy ◽  
Ahmed Alnagdy ◽  
Dina Abd Elfattah ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Open Angle Glaucoma ◽  
Implant Surgery ◽  
Late Failure ◽  
Group I ◽  
The Mean ◽  
The Difference ◽  
One Year ◽  
Age Range

AIM: To compare the outcome of an Ex-Press implant and subscleral trabeculectomy (SST) in the management of glaucoma after previous trabeculectomy on a fibrotic bleb. METHODS: This randomized prospective study included 28 eyes from 28 patients (age range: 42-55y) with primary open angle glaucoma (POAG) presented with elevated intraocular pressure (IOP) with fibrotic bleb despite previous SST for more than 4mo. The eyes enrolled in the study were divided into two groups: group I (subjected to Ex-Press implant surgery) and group II [subjected to SST with mitomycin C (MMC)]. The follow-up continued one year after surgery to evaluate IOP, visual acuity (VA), visual field (VF), and postoperative complications. RESULTS: A significant decrease in IOP was found in both groups with a higher reduction in Ex-Press implant surgery with the mean IOP of 14.50 mm Hg (P=0.001), while the SST group recorded the mean IOP of 16.50 mm Hg (P=0.001) after one year. However, the difference between the two groups in terms of the decrease in IOP was insignificant. Fewer postoperative complications were recorded in the Ex-Press implant surgery and more cases requiring further anti-glaucomatous medications were seen in the SST group. Both groups showed stability in terms of VA and VF. CONCLUSION: Ex-Press implant surgery and SST with MMC are two surgical alternatives for controlling IOP in late failure that occurs more than 4mo after previous SST with a fibrotic bleb. However, Ex-Press shunt is a safer surgery with fewer complications.

scholarly journals Predictors of endoscopic prophylaxis for rebleeding in esophageal varices combined type 2 gastroesophageal varices

2019 ◽  
Author(s):  
Yuan Nie ◽  
Mei-Chun Jiang ◽  
Yue Zhang ◽  
Si-Zhe Wan ◽  
Cong Liu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Esophageal Varices ◽  
Endoscopic Treatment ◽  
Decompensated Cirrhosis ◽  
Gastroesophageal Varices ◽  
Loss To Follow Up ◽  
Logistic Analysis ◽  
Multivariate Logistic Analysis

Abstract Background and Aim Decompensated cirrhosis patients with esophageal varices (EVs) combined type 2 gastroesophageal varices (GOV2) have rebleeding risk after endoscopic prophylaxis. This study was performed to evaluate the preventive efficacy of endoscopic treatment in patients with EVs combined GOV2, and seek out the risk factor of rebleeding.Methods We performed a single-center, observational, retrospective study of patients with EVs combined GOV2 extracted from hospitalization. The biochemical examination, demographics, endoscopic performance and treatment methods of patients undergoing endoscopic treatment were collected. All patients were observed until 1-year, or loss to follow-up. The predictors parameter of rebleeding were analyzed by logistic regression analysisResults A total of 124 patients underwent endoscopic treatment, including 2 (1.6%) patients failed to stop bleeding, 19 (15.3%) patients loss to follow-up. 103 patients were observed until 1-year, including 11 (10.7%) patients had rebleeding. The results had indicated EVs+GOV2 with GOV1, Age, PTA, Bilirubin, Platelet count, Child-Pugh, MELD were associated with rebleeding at 1-year in patients with EVs combined GOV2. Multivariate logistic analysis defined that Age, EVs+GOV2 with GOV1, Bilirubin, PTA were independent risk factor for rebleeding.

scholarly journals Spectroscopy of candidate electromagnetic counterparts to gravitational wave sources

2016 ◽  
Vol 12 (S324) ◽  
pp. 283-286
Author(s):  
Iain A. Steele ◽  
Chris M. Copperwheat ◽  
Andrzej S. Piascik
Keyword(s):  
Black Hole ◽  
Gravitational Wave ◽  
Wide Field ◽  
Solar System Objects ◽  
Multi Wavelength ◽  
Binary Mergers ◽  
Black Hole Binary ◽  
Field Imaging ◽  
Wide Field Imaging

AbstractA programme of worldwide, multi-wavelength electromagnetic follow-up of sources detected by gravitational wave detectors is in place. Following the discovery of GW150914 and GW151226, wide field imaging of their sky localisations identified a number of candidate optical counterparts which were then spectrally classified. The majority of candidates were found to be supernovae at redshift ranges similar to the GW events and were thereby ruled out as a genuine counterpart. Other candidates ruled out include AGN and Solar System objects. Given the GW sources were black hole binary mergers, the lack of an identified electromagnetic counterpart is not surprising. However the observations show that it is possible to organise and execute a campaign that can eliminate the majority of potential counterparts. Finally we note the existence of a “classification gap” with a significant fraction of candidates going unclassified.

scholarly journals Clinical, Histopathological, and Prognostic Characteristics of Patients with Prostate Cancer in Lubumbashi, Democratic Republic of Congo

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Pitchou Mukaz Mbey ◽  
Olivier Mukuku ◽  
Willy Kalau Arung ◽  
Guylain Kitoko Tengu ◽  
Nasser Lubosha Amisi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Specific Antigen ◽  
Public Health Problem ◽  
Elderly Subjects ◽  
Republic Of Congo ◽  
The Mean ◽  
The University

Introduction. Prostate cancer is currently a public health problem with a frequency that varies from country to country. This study aims to describe the epidemiological, clinical, and histopathological and outcome features of prostate cancer in Lubumbashi in the Democratic Republic of Congo. Materials and Methods. This was a descriptive longitudinal study of patients diagnosed with prostate cancer at the University Clinics of Lubumbashi. The study period was 3 years (2017 to 2019). Parameters studied were age and clinical, biological (PSA level, prostatic specific antigen), histopathological, and outcome features. Results. The mean age of patients was 68.7 years (range: 47 and 90 years). The 60 to 69 age group was the most affected (43.18%). Elderly subjects (≥60 years old) represented 89.77% of the cases (n = 79). Voiding disorders were the main reason for consultation in 55.68% of the cases. The mean PSA level was 133.7 ng/ml (range: 4 and 1564.5 ng/ml) at diagnosis and 125.4 ng/ml after 3 months of follow-up (range: 0.16 and 1782.1 ng/ml). Adenocarcinoma was the predominant histological type (100%). In prognosis, 31.82% of patients had a Gleason score greater than 7 and 59.10% had a high risk at the D’Amico risk classification for Prostate Cancer. Hormone therapy was administered alone in 75% of the cases and in combination with pulpectomy in 13.64% of the cases. The 3-year overall survival was 56.82%. Conclusion. Prostate cancer is frequent and has a poor outcome in our country. The establishment of an individual screening policy would be an undeniable advantage in improving the prognosis.

scholarly journals PENGUASAAN BAHASA INGGRIS MAHASISWA BARU UNY TAHUN AKADEMIK 2005/2006 – 2009/2010 PADA KRITERIA TOEFL-LIKE

LITERA ◽  
2013 ◽  
Vol 11 (2) ◽  
Author(s):  
Bambang Sugeng
Keyword(s):  
Standard Deviation ◽  
International Programs ◽  
Study Program ◽  
Graduation Requirement ◽  
Study Programs ◽  
New Students ◽  
The Mean ◽  
Research Questions ◽  
The University

Four research questions are proposed related to (1) students’ English proficiencylevels at the university and faculty levels, (2) their English proficiency levels in each study program, (3) their proficiency in Listening, Structure, and Reading, and (4) possible activities as follows-ups of the TOEFL-Like tests. Using the survey research design, the study involved 24,909 YSU new students of the academic years 2005–2009. Data were analyzed quantitatively using the mean, standard deviation, frequency, and percentages. The results are as follows. First, on the university level, students attain a mean score of 367 (intermediate) with a standard deviation of 50.65 (high homogeneity). On the faculty level,they attain a mean score of 378.81 (FMIPA), 372.83 (FISE), 367.18 (FT), 363.83 (FBS), 363.77 (FIP), and 356.44 (FIK). Second, highest scores are achieved by four study programs (400 or higher), the second by 13 study programs (375 – 399), the third by 45 study programs (350 – 374), and the lowest scores by eight study programs (349 or lower). Third, the score attainment is 35.5% (Reading), 31.25% (Structure), and 27.2% (Listening). Fourth, possible follow-up activities are elevation of students’ TOEFL scores, course placements, improvement of MKU English, planning and implementation of international programs, and graduation requirement for S-1.

P–651 Strict embryo-endometrial synchrony does not contribute to the successful pregnancy during vitrified-warmed embryo transfer with hormone replacement cycles

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
T Takahashi ◽  
K Ota
Keyword(s):  
Embryo Transfer ◽  
Endometrial Thickness ◽  
Hormone Replacement ◽  
Time Lapse ◽  
Successful Pregnancy ◽  
Logistic Analysis ◽  
Significant Difference ◽  
The Mean ◽  
Multivariate Logistic Analysis

Abstract Study question Does strict embryo-endometrium synchronization relate to pregnancy during vitrified-warmed embryo transfer (ET) with hormone replacement (HRT) cycles? Summary answer A 12-hour delay in the embryo-endometrial synchrony was acceptable, and this delay was not an independent predictor of pregnancy during vitrified-warmed ET with HRT cycles. What is known already Embryo-endometrium synchrony is considered to be necessary for successful pregnancy in both fresh and frozen-thawed cycles. Until now, the date of ET has been determined by the synchronization of the embryo developmental stage and the endometrium on a daily basis. To date, with the advent of the time-lapse incubator, it is possible to observe the embryo development from fertilization over time and to calculate the exact time from fertilization of the transferred embryo. However, there are very few studies on the extent to which increases the accuracy of synchronization between embryo and endometrium contributes to a successful pregnancy. Study design, size, duration This retrospective cohort study included 319 consecutive cycles during vitrified-warmed ET with HRT between August 2016 and August 2018. This study was conducted in an academically affiliated private practice. Participants/materials, setting, methods We analyzed 319 vitrified-warmed single-blastocyst transfer cycles. All frozen expanded blastocysts were inseminated by intracytoplasmic sperm injection (ICSI) and cultured in a time-lapse incubator. We calculated time for the in vitro culture of the embryo after ICSI (t1) and time for progesterone-priming (t2) up to ET. The difference between t1 and t2 (delta-t) was used as an indicator of embryo-endometrium synchrony. We examined the relationship between delta-t and treatment outcomes using multivariate logistic analysis. Main results and the role of chance The mean patient’s age at oocyte retrieval was 35.7 (SD 4.3). The number of pregnant cycles was 157 in all treatment cycles (pregnancy rate, 49.2%). The mean value of delta-t was 9.9 h (SD 2.6) in all cycles. There was no significant difference of delta-t in pregnant (mean, SD: 10.0 h, 2.8 h) and non-pregnant cycles (mean, SD: 10.0 h, 2.3 h). Treatment cycles were classified according to the quartile of delta-t, and we examined the percentages of pregnant cycles in each group. There were no significant differences in pregnancy rates among the groups (p = 0.75). On multivariate logistic analysis, patient’s age (adjusted odds ratio [aOR]: 0.94, 95% confidence interval [CI]: 0.89–0.99), previous treatment cycles (aOR: 0.74, 95% CI: 0.56–0.99), endometrial thickness at ET (aOR: 1.19, 1.04–1.36), and good quality blastocysts (&gt;3BB according to Gardner’s classification) at vitrification (aOR: 2.49, 95% CI: 1.23–5.05) were independent predictive factors for pregnancy. On the other hand, delta-t did not contribute to pregnancy (aOR: 1.00, 95% CI: 0.99–1.00). Limitations, reasons for caution We did not examine the effects of embryo-endometrium synchrony during vitrified-warmed ET in a natural cycle. Therefore, careful interpretation of the significance of embryo-endometrium synchrony during the vitrified-warmed ET should be taken. Wider implications of the findings: We showed the embryo-endometrium synchrony did not contribute to the pregnancy during vitrified-warmed ET with HRT cycles. These results cast doubt on the existence of an optimal implantation window by changing the timing of ET with the results of gene expression testing of the endometrium. Trial registration number Not applicable

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