scholarly journals Clinical, Histopathological, and Prognostic Characteristics of Patients with Prostate Cancer in Lubumbashi, Democratic Republic of Congo

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Pitchou Mukaz Mbey ◽  
Olivier Mukuku ◽  
Willy Kalau Arung ◽  
Guylain Kitoko Tengu ◽  
Nasser Lubosha Amisi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Specific Antigen ◽  
Public Health Problem ◽  
Elderly Subjects ◽  
Republic Of Congo ◽  
The Mean ◽  
The University

Introduction. Prostate cancer is currently a public health problem with a frequency that varies from country to country. This study aims to describe the epidemiological, clinical, and histopathological and outcome features of prostate cancer in Lubumbashi in the Democratic Republic of Congo. Materials and Methods. This was a descriptive longitudinal study of patients diagnosed with prostate cancer at the University Clinics of Lubumbashi. The study period was 3 years (2017 to 2019). Parameters studied were age and clinical, biological (PSA level, prostatic specific antigen), histopathological, and outcome features. Results. The mean age of patients was 68.7 years (range: 47 and 90 years). The 60 to 69 age group was the most affected (43.18%). Elderly subjects (≥60 years old) represented 89.77% of the cases (n = 79). Voiding disorders were the main reason for consultation in 55.68% of the cases. The mean PSA level was 133.7 ng/ml (range: 4 and 1564.5 ng/ml) at diagnosis and 125.4 ng/ml after 3 months of follow-up (range: 0.16 and 1782.1 ng/ml). Adenocarcinoma was the predominant histological type (100%). In prognosis, 31.82% of patients had a Gleason score greater than 7 and 59.10% had a high risk at the D’Amico risk classification for Prostate Cancer. Hormone therapy was administered alone in 75% of the cases and in combination with pulpectomy in 13.64% of the cases. The 3-year overall survival was 56.82%. Conclusion. Prostate cancer is frequent and has a poor outcome in our country. The establishment of an individual screening policy would be an undeniable advantage in improving the prognosis.

scholarly journals Improvement of SCD morbimortality in children: experience in a remote area of an African country

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Benoît Mukinayi Mbiya ◽  
Didier Kalenda Kalombo ◽  
Yannick Nkesu Mukendi ◽  
Valery Daubie ◽  
John Kalenda Mpoyi ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
African Country ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Public Health Problem ◽  
Cell Disease ◽  
Republic Of Congo ◽  
Reference Center

Abstract Background Sickle cell disease (SCD) is a public health problem in the Democratic Republic of Congo. While reference sickle cell centers have been implemented in capital cities of African countries and have proven to be beneficial for SCD patients. In the Democratic Republic of Congo, they have never been set up in remote areas for families with low or very low sources of income. Method A cohort of 143 children with SCD aged 10 years old (IQR (interquartile range): 6–15 years) (sex ratio male/female = 1.3) were clinically followed for 12 months without any specific intervention aside from the management of acute events, and then for 12 months with a monthly medical visit, biological follow-up, and chemoprophylaxis (folic acid/penicillin), adequate fluids and malaria prevention. Results The median age of patients at the diagnosis of SCD was 2 years (IQR: 1–5). The implementation of standardized and regular follow-ups in a new sickle cell reference center in a remote city showed an increase in the annual mean hemoglobin level from 50 to 70 g/L (p = 0.001), and a decrease in the lymphocyte count and spleen size (p < 0.001). A significant decrease (p < 0.001) in the average annual number of hospitalizations and episodes of vaso-occlusive crises, blood transfusions, infections, and acute chest syndromes were also observed. Conclusions The creation of a sickle cell reference center and the regular follow-up of children with sickle cell disease are possible and applicable in the context of a remote city of an African country and represent simple and accessible measures that can reduce the morbimortality of children with sickle cell disease.

scholarly journals Impact of the Healing in Harmony program on women's mental health in a rural area in South Kivu province, Democratic Republic of Congo

2021 ◽  
Vol 8 ◽  
Author(s):  
Justin Cikuru ◽  
Ali Bitenga ◽  
Juvenal Bazilashe Mukungu Balegamire ◽  
Prince Mujumbe Salama ◽  
Michelle M. Hood ◽  
...  
Keyword(s):  
Mental Health ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Women’S Mental Health ◽  
Post Traumatic Stress ◽  
Republic Of Congo ◽  
Women's Mental Health ◽  
Relative Risks ◽  
Post Test

Abstract Background To assess whether Healing in Harmony (HiH), a form of music therapy, improved women's mental health following conflict-related trauma and sexual violence in the Democratic Republic of Congo. Methods This study used a step-wedged design and included 167 women, who completed up to two pre-tests, a post-test, and up to two follow-up interviews at 3 and 6 months after completing the program. The Hopkins Symptoms Checklist was used to measure anxiety and depression. The Harvard Trauma Questionnaire was used to measure post-traumatic stress disorder (PTSD). Generalized estimating equations with unstructured covariance were used to estimate mean change in mental health scores and relative risks (RRs) for screening positive. Results Prior to starting the HiH program, 73.9, 84.2, and 68.5% screened positive with median scores being 2.20, 2.70, and 2.06 for depression, anxiety, and PTSD, respectively. The RR for screening positive declined significantly (RR = 0.49 for depression, 0.61 for anxiety, and 0.54 for PTSD) and mean scores declined significantly by −0.54, −0.67, and −0.53 points, respectively, from the pre- to the post-test, declines that were sustained at the 3-month and 6-month follow-up interviews. Conclusion The HiH program was associated with significant improvement in women's mental health that was sustained up to 6 months post completion of the program despite instability in the region and evidence of continued experience of conflict-related trauma during the study. These data support the value of providing psychological care in the context of ongoing humanitarian crises.

scholarly journals Follow-up of a historic cohort of children treated for severe acute malnutrition between 1988 and 2007 in Eastern Democratic Republic of Congo

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0229675 ◽  
Author(s):  
Pacifique Mwene-Batu ◽  
Ghislain Bisimwa ◽  
Gaylord Ngaboyeka ◽  
Michelle Dramaix ◽  
Jean Macq ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Severe Acute Malnutrition ◽  
Acute Malnutrition ◽  
Republic Of Congo ◽  
Historic Cohort

scholarly journals Infection with Hepatitis B and C Virus in the Democratic Republic of Congo: A Public Health Problem

OALib ◽  
2018 ◽  
Vol 05 (08) ◽  
pp. 1-6
Author(s):  
Ben Ilunga Bulanda ◽  
Berry Ikolango Bongenya ◽  
Jean-Yves Debels Kabasele ◽  
Médard Omakoy Okonda ◽  
Divine Chuga ◽  
...  
Keyword(s):  
Public Health ◽  
Hepatitis B ◽  
Health Problem ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Public Health Problem ◽  
Republic Of Congo

scholarly journals Lesional diagnostic approach of common dermatoses in children at the University Clinics of Kinshasa – Democratic Republic of Congo

2020 ◽  
Vol 11 (e) ◽  
pp. e80.1-e80.8
Author(s):  
Lydie Joelle Seudjip Nono ◽  
Hugues D. Adegbidi ◽  
Adama Traore ◽  
Paulo Bunga Muntu
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Diagnostic Approach ◽  
Republic Of Congo ◽  
The University

scholarly journals Prevalence of Hypertension and Associated Factors in Lubumbashi City, Democratic Republic of Congo: A Community-Based Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Jacques Mbaz Musung ◽  
Placide Kambola Kakoma ◽  
Clarence Kaut Mukeng ◽  
Stéphane Lubamba Tshimanga ◽  
Jeef Paul Munkemena Banze ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Associated Factors ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Republic Of Congo ◽  
History Of ◽  
The Mean

Background. Hypertension is the leading cause of cardiovascular disease morbidity and mortality worldwide. Its struggle involves knowing its prevalence. Insufficient data on hypertension in adults in Lubumbashi, Democratic Republic of Congo (DRC), prompted the conduct of this study. The objectives were to determine the prevalence of hypertension and to identify the associated factors in adults in Lubumbashi. Methodology. A cross-sectional study was carried out among 6,708 adults from October 15th to November 24th, 2018, in Lubumbashi. Anthropometric data, lifestyle, and medical history were collected. Hypertension was defined when the mean of the last two blood pressure (BP) measurements was greater than or equal for systolic (SBP) at 140 mmHg and for diastolic (DBP) at 90 mmHg or a history of taking antihypertensive medication whatever the value of the BP. Logistic regression was used to identify the relative effects of hypertension risk factors and all statistical tests were declared significant at a p value <0.05. Results. The female participants numbered 4479 (66.8%). The mean age of all participants was 47.9 ± 16.5 years. The mean SBP and DBP were 128.4 ± 25.9 mmHg and 79.1 ± 15.3 mmHg, respectively. The overall prevalence of hypertension was 33.6%. This prevalence was statistically higher in women than in men (34.5% vs. 31.7%; p = 0.024 ). After logistic regression, the risk of hypertension increased with age >50 years (aOR = 5.85 [5.19–6.60]), overweight (aOR = 1.25 [1.11–1.41]), obesity (aOR = 1.25 [1.11–1.41]), central obesity (aOR = 1.37 [1.16–1.61]), diabetes mellitus (aOR = 2.19 [1.63–2.95]), alcohol consumption (aOR = 1.21 [1.05–1.39]), nonconsumption of vegetables (aOR = 1.35 [1.02–1.80]), and history of stroke (aOR = 2.57 [1.88–3.51]). Hypertension was inversely associated with being underweight (aOR = 0.68 [0.53–0.87]). Conclusion. The prevalence of hypertension in the city of Lubumbashi is high as in other cities of the DRC and Africa. This situation requires the implementation of prevention, detection, and treatment programs for hypertension.

scholarly journals A Descriptive Study of Perinatal Asphyxia at the University Hospital of Kinshasa (Democratic Republic Of Congo)

2013 ◽  
Vol 59 (4) ◽  
pp. 274-279 ◽  
Author(s):  
T. Biselele ◽  
G. Naulaers ◽  
P. Bunga Muntu ◽  
E. Nkidiaka ◽  
M. Kapepela ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Perinatal Asphyxia ◽  
Descriptive Study ◽  
University Hospital ◽  
Republic Of Congo ◽  
The University
Sign in / Sign up

Export Citation Format

Share Document