scholarly journals The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xiaohang Li ◽  
Chengju Wang ◽  
Xueming Zhang ◽  
Wanli Zhang ◽  
Binbin Deng ◽  
...  
Keyword(s):  
Multiple System Atrophy ◽  
Clinical Symptoms ◽  
Latency Period ◽  
Sympathetic Skin Response ◽  
Autonomic Nerve ◽  
Control Group ◽  
Autonomic Nerve Function ◽  
The Difference ◽  
Sacral Reflex ◽  
P Type

Objectives. To observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson’s disease (PD) and multiple system atrophy P-type (MSA-P) and to analyze their value as a differential diagnostic method. Methods. The data of 30 healthy people, 58 PD patients, and 52 MSA-P patients from the First Affiliated Hospital of Wenzhou Medical University were collected. Electrophysiological bulbocavernosus reflex (BCR) and sympathetic skin response (SSR) were evaluated using the Keypoint EMG/EP system. The latency period, amplitude, and extraction rate of BCR and SSR were compared between the control, PD, and MSA-P groups. Results. The incidence of the related autonomic damage in the PD group was lower than that of the MSA-P group. For BCR, the latency period was shorter and the amplitude and elicitation rates were lower in the PD group than in the MSA-P group. For SSR, the latency period was longer in the MSA-P and PD groups than in the control group, but the difference was not statistically significant. Conclusion. SSR cannot be used to assess autonomic nerve function. PD patients can have clinical symptoms similar to those of MSA-P patients, but the incidence is lower. Both MSA-P and PD patients have a damage to the BCR arc, but the MSA-P patients have a more severe damage.

scholarly journals Sacral Reflex Characteristics of Patients with Multiple System Atrophy

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Zhifang Pan ◽  
Xueming Zhang ◽  
Xun Wang ◽  
Binbin Deng ◽  
Wanli Zhang ◽  
...  
Keyword(s):  
Multiple System Atrophy ◽  
Extraction Rate ◽  
Control Group ◽  
Healthy Controls ◽  
Disease Course ◽  
Initiation Rate ◽  
Rate Decrease ◽  
Reflex Latency ◽  
Significant Difference ◽  
Sacral Reflex

Objectives. To observe and analyze the parameters of the sacral reflex and pudendal nerve somatosensory evoked potential (SSEP) in patients with multiple system atrophy (MSA) with respect to factors such as age, disease course, and subtype and provide evidence for the clinical diagnosis of MSA. Materials and Methods. A total of 51 MSA patients and 30 healthy controls were selected from the First Affiliated Hospital of Wenzhou Medical University from May 2013 to November 2015. Electrophysiological sacral reflex detection and SSEP detection were performed using the Keypoint EMG/EP system. The extraction rate, latency, and amplitude of the sacral reflex and SSEP in the MSA group and control group were compared. Results. The sacral reflex latency and amplitude in patients with MSA were statistically different from those of the healthy controls. The latency of sacral reflex increases with the prolongation of the disease course, and the amplitude and initiation rate decrease with the prolongation of the disease course. There was no significant difference in sacral reflex latency and amplitude between MSA patients of different ages and subtypes. There was no significant difference in the latency or amplitude of SSEP between the MSA group and healthy control group. Conclusions. The latency of sacral reflex increases with the prolongation of the disease course, and the amplitude and extraction rate decrease with the prolongation of the disease course. There was no significant difference in the parameters of sacral reflex between young MSA patients and elderly patients. And there was no statistically significant difference between MSA-P subtypes and MSA-C subtypes. This trial is registered with ISRCTNCR2009041.

scholarly journals Clinical Characteristics And Prognosis of Vasovagal Syncope With Sinus Arrest In Children

2021 ◽  
Author(s):  
Rui Sun ◽  
Yingying Kang ◽  
Yeshi Chen ◽  
Xiaohui Li ◽  
Mingming Zhang ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Clinical Symptoms ◽  
Vasovagal Syncope ◽  
Interquartile Range ◽  
Autonomic Nerve ◽  
Sinus Arrest ◽  
Oral Rehydration ◽  
Autonomic Nerve Function ◽  
Oral Rehydration Salts

Abstract The aim of this study was to analyze the clinical characteristics and prognosis of vasovagal syncope(VVS) with sinus arrest in children. From July 2017 to October 2020, cases of VVS with sinus arrest were recruited from patients diagnosed as VVS in our department. The clinical data, the results of the head-up tilt testing (HUTT), and follow-up information were analyzed. 223 patients were diagnosed as VVS during the time, and 10 cases of VVS with sinus arrest were recruited, who had a median age of 9.5 years（interquartile range: 6.8 to 10.4 years), a gender ratio of 1:1, and median sinus arrest time of 7.7s(range: 3.39 to 19s). These patients were given oral rehydration salts and orthostatic training, as well as 2 children treated with metoprolol and 5 children with sertraline hydrochloride. No child was implanted with pacemakers. During a median of 26 months of follow-up (interquartile range: 21 to 33 months), only one of the children had once syncope episode, three children had 1~4 times of prodromal symptoms. Conclusion The present research most crucial finding was that VVS patients with sinus arrest in children were younger than ordinary pediatric VVS patients. Oral rehydration salts(ORS) and autonomic nerve function exercise may improve clinical symptoms in children with VVS accompanied by sinus arrest. Pacemakers for VVS with sinus arrest in children should be cautious.

scholarly journals High-Quality Nursing Care for the Elderly in the Department of Otolaryngology

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Yeping Huang ◽  
Huili Chen
Keyword(s):  
Nursing Care ◽  
Clinical Symptoms ◽  
The Elderly ◽  
Modern Technology ◽  
Control Group ◽  
Nursing Interventions ◽  
Observation Group ◽  
Nursing Satisfaction ◽  
Scale Scores ◽  
The Difference

ENT patients have different types of diseases and clinical symptoms, and generally, patients have a low level of understanding of their professional knowledge about their ENT diseases. In this paper, quality nursing interventions in otorhinolaryngology require nursing staff to implement relevant nursing interventions in the process of implementing relevant nursing care, which should be based on patients’ needs, and guide patients to perform rehabilitation exercises according to their individual conditions, in addition to establishing continuous nursing interventions with patients at the time of discharge with the help of modern technology. By comparing the nursing satisfaction of patients in the observation group and the control group, it was found that the nursing satisfaction of patients in the observation group who received humanistic nursing was higher, and the difference was statistically significant compared with that of the control group ( P < 0.05 ). The SCL-90 scale scores of patients in both groups were not significantly different on the day of admission as verified by t values, and the SCL-90 scale scores of patients in both groups changed to a certain extent after hospitalization. The difference between the two groups was verified by t value.

scholarly journals Biliary system functional condition in patients with chronic cholecystitis against the background of diabetes mellitus type 2

2019 ◽  
Vol 84 (3) ◽  
pp. 30-37
Author(s):  
L.V. Zhuravlyova ◽  
G.Yu. Tymoshenko
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Clinical Symptoms ◽  
Latency Period ◽  
Functional Condition ◽  
Chronic Cholecystitis ◽  
Diabetes Mellitus Type ◽  
Biliary System ◽  
Control Group

Overlay of diseases of the biliary system to diabetes mellitus type 2 can contribute to the enhancement of disorders of protein, lipid and carbohydrate metabolism and affect the mechanisms of regulation at the cellular molecular level. Therefore, the need for early diagnosis and study of the features of the course of chronic cholecystitis against the background of diabetes mellitus type 2 is a pressing issue of internal medicine. The motor-evacuation and cholecretory functions of the biliary system and the features of the course of chronic cholecystitis on the background of diabetes mellitus type 2 were studied. 93 patients were examined, of which 62 were patients with combined diabetes mellitus type 2 and chronic cholecystitis and 31 patients with isolated chronic cholecystitis. The control group was represented by 20 apparantly healthy individuals, who were representative of the age and number of male and female probands. The course of chronic cholecystitis was found to be accompanied by impaired gallbladder motor (evacuation) function, which was manifested by an increase in the latency period, the volume of the cavity of the gallbladder, the emptying coefficients in the dynamics and a decrease in the index of contraction of the gallbladder. In the presence of diabetes mellitus type 2, an atypical course of chronic cholecystitis may be formed, characterized by motor-evacuation disorders of the biliary tract and physico-chemical changes in bile, the severity of which exceeds those of isolated chronic cholecystitis. The peculiarities of the course of chronic cholecystitis in patients with diabetes mellitus type 2 are manifested by insignificant clinical symptoms and distinct changes at both stages of cholecystosonography, which may be the result of the development of autonomic neuropathy. In diabetes mellitus type 2, it is advisable to determine the status of the gallbladder (cholecystosonography) in order to prevent the risk of complications (cholelithiasis) and timely administration of antimicrobial therapy in the presence of an additional inflammation.

scholarly journals Value of TCD Foaming Test in Screening Patent Foramen Ovale in Migraine Patients and Efficacy of PFO Occlusion

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Lilan Du ◽  
Xiaorong Guo ◽  
Honglin Zhang ◽  
Min Zhang ◽  
Guangli Zou
Keyword(s):  
Physical Examination ◽  
Patent Foramen Ovale ◽  
Clinical Symptoms ◽  
Control Group ◽  
Observation Group ◽  
Foramen Ovale ◽  
Occlusion Therapy ◽  
Vas Score ◽  
Before And After ◽  
The Difference

Objective: To explore the effect of TCD foaming test in screening patent foramen ovale in migraine patients, as well as in the treatment effect. Methods: From September 2019 to August 2020, 236 patients with migraine and 362 patients with normal physical examination were treated in our hospital. According to the random number table method, 60 patients with migraine were selected as the observation group, and 60 patients with normal physical examination were selected as the control group. 48 cases of PFO were confirmed by TCD foaming test Among the patients with migraine, 36 patients received interventional occlusion therapy. The therapeutic effect and VAS score of the two groups were analyzed. Results: Through TCD foaming test, the proportion of PFO in the observation group was 80%, and that in the control group was 13.33%. The proportion of PFO in the observation group was significantly higher than that in the control group, and the difference was statistically significant (X2 = 53.5714, P < 0.01);The symptoms disappeared in 30 patients and improved in 4 patients; Among the 36 patients who received interventional occlusion therapy, the VAS score of patients before and after the operation was significantly changed, and the proportion of patients whose pain disappeared after the operation was 83.33%, which was significantly lower than that before the operation, and the difference was comparable (X2 = 51.4286, P < 0.01). Conclusion: TCD foaming test for PFO screening has strong applicability, not only safe and convenient, will not cause trauma to patients, and through interventional occlusion treatment, can significantly improve the clinical symptoms of migraine patients and cure patients.

scholarly journals The Influence of Nursing Intervention on Diabetic Patients with High Blood Pressure

2015 ◽  
Vol 4 (3) ◽  
pp. 16
Author(s):  
Yun Wu
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Clinical Symptoms ◽  
Statistical Significance ◽  
Nursing Intervention ◽  
Control Group ◽  
Diabetic Patients ◽  
Nursing Satisfaction ◽  
The Difference ◽  
Experimental Group

<strong>Objective:</strong> To observe the clinical symptoms of diabetes patients with high blood pressure, highlighting the influence and application value of nursing intervention on diabetic patients with hypertension. <strong>Methods: </strong>The data of 80 cases of diabetic patients with high blood pressure in our hospital from December 2011 to January 2011 were retrospectively analyzed. The patients were randomly divided into the experiment group and the control group. There were 40 patients of each group. Both patient groups were treated by the same means, subsequently, the control group were given routine nursing, while the experimental group were given programmed nursing to conduct care intervention. Finally, both clinical nursing effects were compared. <strong>Results:</strong> The numbers of patients with curative effect evaluation in the experimental group were marked higher than the control group patients. In terms of nursing satisfaction, the number of satisfied patients was larger than the control group, and the difference of the two groups was statistical significance (<em>p</em> &lt; 0.05). <strong>Conclusion:</strong> Nursing intervention can strengthen the therapeutic effect of drugs, help to improve the cognitive ability of diabetic patients clinically which also improves the quality of life of the patients.

scholarly journals Clinical Study of Simple Plasma Exchange in the Treatment of Severe Autoimmune Hepatitis

2015 ◽  
Vol 4 (2) ◽  
pp. 7
Author(s):  
Qiaoai Hong ◽  
Xiaoping Xu ◽  
Maojun Yao ◽  
Zhangshu Qu
Keyword(s):  
Autoimmune Hepatitis ◽  
Plasma Exchange ◽  
Total Bilirubin ◽  
Clinical Symptoms ◽  
Combined Treatment ◽  
Control Group ◽  
Comprehensive Treatment ◽  
The Difference ◽  
And Control ◽  
Single Plasma

<p><strong>Objectives: </strong>Plasma Exchange (PE) in the treatment of severe autoimmune hepatitis and the clinical outcome of the clinical data were retrospectively analyzed. The clinical efficacy and safety of single plasma exchange (PE) in the treatment of autoimmune hepatitis were also evaluated. <strong>Method: </strong>The PE group of 22 patients was given conventional treatment of combined treatment of patients with simple PE while 21 cases of the control group were treated with comprehensive treatment. The efficacy of PE group and control group were compared within 2 weeks. <strong>Results</strong><strong>: </strong>The clinical symptoms of 22 patients in PE group were significantly improved (<em>p </em>&lt; 0.05); in total bilirubin (TBIL), (AST), (INR), (ALT) where the PE group (17/22) 77.27%, and control group (10/21) 47.62%. The difference was statistically significant (<em>p </em>&lt; 0.05). <strong>Conclusion: </strong>Pure plasma exchange (PE) is an effective method for the treatment of severe autoimmune hepatitis (AIH).</p>

scholarly journals Effect of Deep Relaxation on Heart Rate Variability in Sedentary Females

2014 ◽  
Vol 8 (2) ◽  
pp. 65-69 ◽  
Author(s):  
Monzur E-Fatema ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Heart Diseases ◽  
Relaxation Technique ◽  
Autonomic Nerve ◽  
Personal Contact ◽  
Control Group ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
Apparently Healthy

Background: Sedentary lifestyle is associated with low heart rate variability (HRV). Deep Relaxation Technique (DRT) increase HRV which reduces the risk of coronary heart diseases. Objectives: To assess HRV after practicing DRT to find out it’s effect on cardiac autonomic nerve function in sedentary subjects. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University between July 2012 and June 2013 on 30 apparently healthy sedentary females aged 25-35 years (study) who were practicing DRT with 3 months duration. For comparison, age and BMI matched 30 apparently healthy sedentary females who had no experience of relaxation technique (control) were also studied. Both groups were selected from the sedentary housewives by personal contact. The study subjects were the participants in a private yoga center in Dhaka. HRV was assessed by a Polygraph. Statistical analysis was done by Independent Sample ttest. Results: Resting mean heart rate (p<0.001) was significantly lower and mean R-R interval and SDNN (p<0.001), RMSSD (p<0.05) were significantly higher in the relaxation group than the control group. Conclusion: DRT improves cardiac autonomic nerve function with parasympathetic dominance in sedentary females. DOI: http://dx.doi.org/10.3329/jbsp.v8i2.18656Bangladesh Soc Physiol. 2013, December; 8(2): 65-69

scholarly journals Evaluation of Clinical Symptoms and Serum Lead Level in Patients with History of Oral Opium Use being Admitted to Hazrat Rasoul Akram, Firoozgar, Firoozabadi and Haft Tir Hospitals, Tehran

2019 ◽  
pp. 1-8
Author(s):  
Majid Rezaei Tavirani ◽  
Hazhir Heidari Beigvand
Keyword(s):  
Clinical Symptoms ◽  
Middle Eastern ◽  
Lead Level ◽  
Serum Levels ◽  
Control Group ◽  
Case Group ◽  
History Of ◽  
The Mean ◽  
The Difference ◽  
Opiate Addicts

Introduction: Drug abuse and its complications is a socio-health problem in Middle Eastern countries such as Iran. Smugglers may add lead to drug during drug production, which is in order to increase its weight for greater benefit. Considering the frequency of the patients with various complaints among Iranians, this study was designed and conducted to evaluate the clinical symptoms and serum levels of lead in patients being admitted to Hazrat Rasoul Akram, Firoozgar, Firouzabadi and Haft Tir hospitals with any complaints. Materials and Methods: In this case-control study, serum levels of lead were measured in 128 samples in case and control groups. The case group consisted of 64 patients using oral opium who being admitted to Rasoul Akram and Firoozgar, Haft Tir and Firouzabadi hospitals with different complaints in May 2017. The control group consisted of 64 patients with no history of addiction that were homogenized with the case group in terms of age and sex. They were evaluated for serum levels of lead and other variables. Data were analyzed by SPSS software. Results: The mean serum lead level was 76.34±17.82 in the group using opium and was 7.68±3.72 in the control group that the difference was statistically significant (P <0.001). The most common complaints of patients were abdominal pain and symptoms of bowel obstruction. The mean rate of oral opium consumption was 1.73±0.23 in subjects under 50 years old and with a mean of 2.89±0.27 in subjects over 50 years old. Serum lead level was significantly (P = 0.032) increased compared to the amount consumed. Duration of oral opium consumption was 5 months to 30 years with a mean of 15.24 years, which was not significantly correlated to serum lead level (P = 0.213). Also, the hemoglobin range was significantly correlated to different levels of lead in patients consuming oral opium (P = 0.027). Conclusion: The findings of the present study showed a high mean serum lead level in oral opium addicts in the study population. The results also confirm numerous reports suggesting the definitive diagnosis of lead poisoning as a justifying factor in addicted patients with nonspecific symptoms, which may indicate the need for serum lead level screening in opiate addicts to prevent more serious complications.

scholarly journals Clinical Effect of Naomaitong in Treating Cerebrovascular Diseases

2020 ◽  
Vol 218 ◽  
pp. 03008
Author(s):  
Wentao Zhang ◽  
Ping Zuo ◽  
Feng Wang ◽  
Yinglin Cui
Keyword(s):  
Clinical Effect ◽  
Clinical Symptoms ◽  
Research Work ◽  
Test Group ◽  
Cerebrovascular Diseases ◽  
Control Group ◽  
Therapeutic Effects ◽  
Oral Liquid ◽  
Improvement Effect ◽  
The Difference

Objective: To explore the clinical effect of applying Naomaitong in the treatment of cerebrovascular diseases. Method: The research work was carried out in our hospital from November 2018 to November 2019. A total of 100 patients were selected in this study, all of whom were cerebrovascular disease patients, and they were divided into two groups on average. Naofukang injection was named as the control group, and the other group was given Naofukang injection combined with Naomaitong oral liquid, and the therapeutic effects of the two groups were compared and analyzed. Results: The treatment efficiency of the patients in the test group and the control group were 94.00% and 82.00%, respectively. The effectiveness in the test group was higher. The difference in FIB and PagT levels between the two groups before treatment was small, P>0.05, which was non-significant. After the intervention, the FIB and PagT levels in the test group were lower, and the improvement effect was more significant. The difference between the two groups was P<0.05, which was significant.Conclusion: The application of Naomaitong therapy in the treatment of cerebrovascular diseases has a significant effect. It can reduce the incidence of adverse reactions in patients and improve the clinical symptoms of patients, which has a positive significance for clinical development.

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