scholarly journals Research Achievements of Oral Submucous Fibrosis: Progress and Prospect

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Hui Xu ◽  
Feng-yuan Lyu ◽  
Jiang-yuan Song ◽  
Yu-ming Xu ◽  
Er-hui Jiang ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Treatment Strategies ◽  
Areca Nut ◽  
Health It ◽  
Comprehensive Review ◽  
Potentially Malignant Disorders ◽  
Regional Problem ◽  
Potentially Malignant ◽  
New Ideas ◽  
Submucous Fibrosis

Oral submucous fibrosis (OSMF) is a kind of chronic, insidious disease, and it is categorized into potentially malignant disorders (PMD), which poses a global and regional problem to public health. It is considered to be a multifactorial disease, such as due to areca nut chewing, trace element disorders, and genetic susceptibility. However, there is still no unanimous conclusion on its pathogenesis, diagnosis, and treatment strategies. Hence, this article provides a comprehensive review and prospect of OSMF research, providing scholars and clinicians with a better perspective and new ideas for the research and treatment of OSMF.

scholarly journals Screening of Oral Potentially Malignant Disorders Using Exfoliative Cytology: A Diagnostic Modality

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Arpita Kabiraj ◽  
Tanya Khaitan ◽  
Debarati Bhowmick ◽  
Uday Ginjupally ◽  
Aritri Bir ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Submucous Fibrosis ◽  
Class Ii ◽  
Class I ◽  
Exfoliative Cytology ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Oral Lichen

Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening.Materials and Method. A total of 160 subjects with 25–50 years of age were included in the study. Among them, 40 were clinically diagnosed with oral leukoplakia, 40 were diagnosed with oral lichen planus, 40 were diagnosed with oral submucous fibrosis, and 40 were in the control group. The prepared smears were subjected to Papanicolaou stain and analyzed microscopically for the evaluation of the cytomorphological features.Results and Discussion. When analyzed microscopically, 36 (90%) out of the 40 oral leukoplakic lesions showed Class II cytological features whereas 4 (10%) revealed Class I features. Among 40 patients with oral lichen planus, 26 (65%) showed Class II features while the remaining 14 (35%) revealed Class I features. In 40 subjects with oral submucous fibrosis, 32 (80%) showed Class II features while the other 8 (20%) showed Class I features. All the 40 control subjects showed Class I features. Thus, OEC can be widely advocated as an addition to clinical conclusion and an adjunct to biopsy.

scholarly journals Effectiveness of Long Term Supervised and Assisted Physiotherapy in Postsurgery Oral Submucous Fibrosis Patients

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
S. Kale ◽  
N. Srivastava ◽  
V. Bagga ◽  
A. Shetty
Keyword(s):  
Treatment Options ◽  
Oral Submucous Fibrosis ◽  
Scar Contracture ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Conservative And Surgical Treatment ◽  
Subsequent Relapse

Oral submucous fibrosis is one of the leading potentially malignant disorders prevailing in India. A number of conservative and surgical treatment options have been suggested for this potentially malignant disorder (Arakeri and Brennan, 2013). While the role of physiotherapy has been highlighted in the conservative management, its importance in postsurgical cases to avoid scar contracture and subsequent relapse has not been given due importance in the literature. The following is a case report of a male patient surgically treated for OSMF (oral submucous fibrosis) and meticulously followed up for recalls and physiotherapy. The constant supervision and motivation for physiotherapy along with the constant assistance helped achieve satisfying results.

scholarly journals A Study to Analyze Different Patterns of Quid Usage among Subjects with Oral Submucous Fibrosis in Mangalore Population

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Vidya A. Holla ◽  
L. K. Chatra ◽  
Prashanth Shenai ◽  
Devika Shetty ◽  
Ashwini Baliga
Keyword(s):  
Clinical Stage ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Areca Nut ◽  
Age Group ◽  
Cross Sectional ◽  
Potentially Malignant ◽  
Carcinogenic Effects ◽  
Submucous Fibrosis ◽  
Youth Population

Aim and Objectives. Oral submucous fibrosis (OSF) is a potentially malignant disorder associated with the usage of areca nut. Usage of processed forms of areca nut is popular among the youth and its carcinogenic effects are not well known. Due to large immigrant population, various patterns of areca nut usage are seen. The aim of this study is to assess the various quid chewing patterns and their association with severity of OSF.Materials and Methods. A cross-sectional study was carried out with 250 cases clinically and histologically diagnosed as having OSF lesion that were selected and subjected to a detailed habit history which was recorded through preformed questionnaire. The data obtained was statistically analyzed.Results. Among the 250 subjects, males were seen to be affected more than females within the age group of 26–35 years and were having clinical stage I OSF. A combination of processed areca nut and processed tobacco was used by the majority of the subjects with duration of 1 to 5 years, at a frequency of 3 to 5 quids per day.Conclusion. The present study confirms the association between oral submucous fibrosis and the quid containing processed areca nut and processed tobacco and also highlights the increasing youth population using the processed forms of areca nut.

scholarly journals Perspectives on areca nut with some global implications: Symposium report

2018 ◽  
Vol 3 ◽  
pp. 2057178X1881406 ◽  
Author(s):  
Prakash C. Gupta ◽  
Cecily S. Ray ◽  
Roger L. Papke ◽  
Irina Stepanov ◽  
Samir S. Khariwala ◽  
...  
Keyword(s):  
Physical Dependence ◽  
Oral Submucous Fibrosis ◽  
Storage Conditions ◽  
Control Measures ◽  
International Agency ◽  
Areca Nut ◽  
Adverse Health Outcomes ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Malignant Condition

Areca nut and products made from the nut, evaluated by the International Agency for Research on Cancer as carcinogenic to humans since 2004, are being increasingly used in India and South East Asia and exported to many countries. There is thus an urgent need to identify best control policies and research gaps. On 1 February 2018, a group of experts shared their latest knowledge and perspectives on areca nut at Healis-Seksaria Institute for Public Health in Navi Mumbai, Maharashtra, India. By itself, areca nut has been implicated in oral and oesophageal cancer. Areca nut users are also at high risk of oral submucous fibrosis, a debilitating and potentially malignant condition. Users may also suffer adverse health outcomes due to smokeless tobacco, commonly mixed with areca nut. The use of areca nut commonly begins in childhood and often proceeds to use with tobacco. Gutka, a widely consumed, industrially made areca nut product containing tobacco, has been banned in all states and union territories of India, but it is still widely available. Areca nuts contain arecoline, an alkaloid that stimulates various brain receptors, promoting physical dependence. Areca nut alkaloids have also been implicated in carcinogenesis. Other chemicals, introduced during cultivation and processing of areca nuts, contribute to oral submucous fibrosis and cancer. The wide variety of products, different storage conditions and lack of regulation can lead to significant variation in the content of toxicants, carcinogens and alkaloids, making the psychological and physical dependence issues even more challenging. Regulation of product contents is needed as a part of control measures to supplement product bans.

scholarly journals A Comprehensive Review of Etiopathogenesis of Oral Submucous Fibrosis

2015 ◽  
Vol 6 (2) ◽  
pp. 76-79
Author(s):  
Sukhjinder Kaur Kalra ◽  
Alok A Lathi ◽  
Shilpa A Lathi
Keyword(s):  
Oral Submucous Fibrosis ◽  
Areca Nut ◽  
Betel Nut ◽  
Exact Role ◽  
Comprehensive Review ◽  
Submucous Fibrosis ◽  
Betel Nut Chewing ◽  
Malignant Condition ◽  
Head Neck

ABSTRACT Accepted as an Indian disease, oral submucous fibrosis, is considered not only a chronic debilitating disease but a poten tially malignant condition of oral cavity, strongly associated with the habit of betel nut chewing, that has been sporadically detected in many other western countries and various conti nents, posing a reason for concern in order to create awareness for such debilitating disease. This article provides an overview of the recent concepts and exact role of areca nut alkaloids and other etiological factors in the pathogenesis of oral submucous fibrosis (OSMF). How to cite this article Kalra SK, Lathi AA, Lathi SA. A Com prehensive Review of Etiopathogenesis of Oral Submucous Fibrosis. Int J Head Neck Surg 2015;6(2):76-79.

scholarly journals Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sandeep Kumar ◽  
Nitai Debnath ◽  
Mohammed B. Ismail ◽  
Arunoday Kumar ◽  
Amit Kumar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Indian Population ◽  
Dietary Habits ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Areca Nut ◽  
Oral Potentially Malignant Disorders ◽  
Cross Sectional ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant

Objective. To assess the prevalence of oral potentially malignant disorders and to determine the potential risk factors for its development in Indian population.Materials and Methods. This cross-sectional study was carried out on 1241 individuals in Indore, Madhya Pradesh. A questionnaire was designed to record information about sociodemographic characteristics, oral hygiene practices, dietary habits, and risk factors for oral potentially malignant disorders. Oral mucosal lesions were examined by a skilled person.Results. The overall prevalence of oral potentially malignant disorders was found to be 13.7% with oral submucous fibrosis (8.06%) found to be more common and erythroplakia (0.24%) found to be least prevalent. Results of Logistic Regression analysis showed that males (OR = 2.09,Pvalue < 0.0001) who were ever consumers of tobacco (OR = 2.06,Pvalue = 0.030) and areca nut chewing (OR = 2.64,Pvalue = 0.004) were more likely to develop oral potentially malignant disorders compared to never consumers. Diabetic (OR = 2.21,Pvalue = 0.014) and underweight individuals (OR = 2.23,Pvalue = 0.007) were more likely to suffer from oral potentially malignant disorders.Conclusion. The study reinforces the association of tobacco and areca nut consumption with oral potentially malignant disorders. An association of oral potentially malignant disorders with diabetes and BMI was confirmed by this study.

scholarly journals Coetaneous Presentation of Oral Leukoplakia and Oral Submucous Fibrosis with High Grade Dysplasia and Its Management with Lasers: A Case Report

2021 ◽  
Vol 6 (08) ◽  
pp. 464-469
Author(s):  
Preethi R ◽  
Malarkodi T ◽  
Arvind Krishnamurthy ◽  
Aravind Warrier S
Keyword(s):  
Malignant Transformation ◽  
Oral Submucous Fibrosis ◽  
Oral Leukoplakia ◽  
High Grade Dysplasia ◽  
High Grade ◽  
Oral Potentially Malignant Disorders ◽  
Oral Epithelial Dysplasia ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Submucous Fibrosis

Oral potentially malignant disorders (OPMD) are diverse lesions associated with an increased likelihood for malignant transformation to oral cancer. The most frequently encountered OPMD in clinical practice are Oral Leukoplakia and oral submucous fibrosis (OSMF). The use of tobacco is consistently linked with leukoplakia and areca/betel nut with OSMF. Histopathological features of oral epithelial dysplasia, its varying grades are of immense clinical significance to evaluate its ability for malignant transformation. We report a case of homogenous leukoplakia and OSMF, two oral potentially malignant disorders occurring at the same site with high-grade dysplasia and its management using lasers.

scholarly journals Assessment of Nicotine Dependence Using Fagerstrom Test among Patients with Leukoplakia and Oral Submucous Fibrosis

2020 ◽  
pp. 97-106
Author(s):  
N. Prashaanthi ◽  
Sreedevi Dharman
Keyword(s):  
Nicotine Dependence ◽  
Oral Submucous Fibrosis ◽  
Tobacco Consumption ◽  
Chi Square ◽  
High Dependency ◽  
Potentially Malignant Disorders ◽  
Dental Hospital ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Oral Malignancy

Tobacco consumption has an influence on the oral mucosa and causes oral malignancy in the due time. On assessing nicotine dependence, appropriate counselling can be given to prevent further progression of the habit. Aim of this study was to assess the nicotine dependence levels among patients with potentially malignant disorders such as leukoplakia and Oral Submucous Fibrosis (OSMF) using fagerstrom test. This study included 140 patients from October 2019 to January 2020 in a dental hospital. Variables such as age, gender, tobacco form and lesion were assessed. Descriptive and chi square statistics were performed. Out of 140 patients, higher prevalence with tobacco usage were among 41-50 years (40%), 94.29% were males and 5.71% were females, 16.43% had low dependency, 52.86% had medium dependency and 30.71% had high dependency. Association between   age; nicotine dependency in patients with and without lesion p=0.000(p<0.05), statistically significant. Association between gender and patients with and without lesions p=0.151(p>0.05), statistically not significant. Within the limitations of the present study, males had higher prevalence of tobacco use among 41-50 years. Patients with potentially malignant disorders and smokers without lesion had medium dependence while smokeless tobacco users without lesion had a high dependence.

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