scholarly journals Blood Lead Levels and Associated Sociodemographic Factors among Children Aged 3 to 14 Years Living near Zinc and Lead Mines in Two Provinces in Vietnam

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Thi Giang Hoang ◽  
Quang Phuc Tran ◽  
Van Tung Lo ◽  
Ngoc Hai Doan ◽  
Thu Ha Nguyen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lead Level ◽  
Blood Lead ◽  
Ambient Air ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
The Body ◽  
Lead Contamination ◽  
Health Concern ◽  
Cross Sectional

Lead poisoning in children is a major public health concern worldwide, especially in developing countries. We conducted a cross-sectional study on 403 children aged from 3 to 14 years living nearly zinc–lead mining areas in two provinces in Vietnam (Bac Kan and Thai Nguyen) from 06/2016 to 10/2016 to identify risk factors for lead contamination. Results. The proportion of children with blood   lead   levels   BLLs ≥ 10  μg/dL was 80.51% in Bac Kan and 50% in Thai Nguyen; the mean blood lead level for children was 14.41 ± 9.42  μg/dL. In linear regression analyses, the body mass index was negatively associated with elevated BLLs with r = − 0.404 , p < 0.05 (95% CI: -0.801, -0.006). In multivariable regression analysis, several risk factors were associated with lead contamination including male sex ( aOR = 2.44 , 95% CI: 1.13-5.24, p = 0.02 ), play areas in Bac Kan ( aOR = 2.3 (1.02-5.17), p = 0.04 ), proximity of children’s home of less than 2 kilometers from the mine ( aOR = 2.90 (1.54-5.44), p = 0.001 ), and inattentive symptoms in Thai Nguyen ( aOR = 7.85 , 95% CI 3.49-17.69, p = 0.001 ). Environmental factors, including lead concentrations in the soil and ambient air samples in both locations, are many times higher than Vietnamese standards.

scholarly journals The level of blood lead painter workers Rafsanjan city and its correlation with risk factors for cardiovascular disease in 2019

2020 ◽  
Author(s):  
A Taheri Fard ◽  
H Ahmadinia ◽  
M Kafi ◽  
M Salandari ◽  
A Rahmani ◽  
...  
Keyword(s):  
Blood Sugar ◽  
Work Experience ◽  
Lead Level ◽  
Cardiovascular Effects ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Heart Attacks ◽  
Sugar Levels

Introduction: Painters are exposed to various chemical harmful agents such as lead particles in paints. Some studies have suggested a possible association of occupational exposure that may cause cardiovascular effects. Lead is absorbed through the body through the skin, skin, and respiratory tract and penetrates some tissues. Considering the importance of labor health in each country's development and progress, this study was conducted to determine the amount of lead in the blood of painters in Rafsanjan in 2019. Materials and Methods: The present study is a cross-sectional study of the descriptive type conducted in 1397 on 77 painters of Rafsanjan city. Data collection was done in two stages, in the first stage, based on a checklist that included demographic information, and in the second stage by performing laboratory tests. Finally, by recording the data in SPSS software, quantitative data was reported as a "mean ± standard deviation" and qualitative information as a "number (percent)". Results: Of the 77 painter workers, the youngest is 21, and the oldest is 70 years old. A total of 20 people (26%) had a family history of heart attacks. The highest amount of lead in the blood of painters was reported to be 30.7 micrograms per deciliter, and the level of lead was most correlated with blood sugar. Sixty people (77.9%) painters used personal protective equipment. 49.4% of the study's painters wore work clothes, and 28.6% used gloves while working. Lead levels are directly related to blood sugar, cholesterol, triglyceride, LDL, age, work experience, and blood sugar levels were most correlated with the level of lead in painters' blood. Conclusion: This study's findings show that due to the increase in the work experience of painters, their blood lead level has also increased, and the blood sugar level has had the highest correlation with the lead level in the painters' blood.

scholarly journals Environmental assessment of pediatric Lead exposure in Tehran; a prospective cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hedieh Ahangar ◽  
Afsoon Karimdoost ◽  
Amir Salimi ◽  
Maryam Akhgari ◽  
Scott Phillips ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lead Poisoning ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Industrial Areas ◽  
Floor Dust ◽  
House Floor

Abstract Background Ingestion and inhalation are common routes of exposure for lead in humans. Developing countries still have unacceptably high rates of lead toxicity, especially in children. Studies on probable risk factors of lead poisoning in Iranian children are insufficient. In this study, we aimed to evaluate possible environmental factors in children with high blood lead concentrations living in Tehran and neighboring cities. Methods In a prospective cross-sectional study between March 2018 and March 2019 we followed all children referred from two pediatric gastrointestinal clinics with blood lead level (BLL) > 5 μg/dL in metropolitan Tehran to investigate possible environmental risk factors in their home. Household specimens including scratched wall paint, house floor dust, windowsill dust, tap water, and consumed spice were evaluated using atomic absorption method to detect lead concentrations. Epidemiological and environmental data collected through in-depth interviews with parents/guardians. Industrial areas were defined based on municipality maps on industrial places. Results Thirty of 56 parents/guardians with BLL > 5 μg/dL agreed to be followed through environmental investigation. The only categorical statistically significant risk factor was a history of lead poisoning in the family and living in an industrial zone. There was a positive correlation between BLL and interior windowsills dust lead level, r = 0.46, p = 0.01. Scratched paint lead level and BLL showed a significant positive correlation, r = 0.50, p = 0.005. House floor dust lead level (median = 77.4, p < 0.001) and interior windowsill dust lead level (median = 291, p = 0.011) were both significantly higher than the environmental protection agency (EPA) standards of 40 μg/ft2, 250 μg/ft2. Interior windowsill dust lead concentrations were significantly higher in industrial areas (p = 0.026). Conclusion Children’s playing environment should be cleaned more often to reduce dust. Moreover, specific rules may need to be implemented for paint lead concentrations and air pollution, especially in industrial areas.

Study of the impact of blood lead level on humoral immunity in humans

2002 ◽  
Vol 18 (1) ◽  
pp. 39-44 ◽  
Author(s):  
M ohammad Ayatollahi
Keyword(s):  
Blood Lead Level ◽  
Venous Blood ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
System A ◽  
Organ Systems ◽  
The Impact

The objective was to study the impact of blood lead level (BLL) on serum immunoglobulin levels (SIL; IgG, IgM, IgA) in people with high-risk professions. It has been characterized that BLL / 25 g/dL can cause dysfunctions in different organ systems of the body, such as the immune system. A cross-sectional study was carried out in relation to this, by using a pretested questionnaire to collect data on demographic factors and socioeconomic status, which was completed by subjects studied, such as car battery shop workers, car painters and welders of car radiators and exhausts, printing office workers (typesetters and nontypesetters) who were aged between 15 and 70 years. Venous blood was sampled to measure the BLL (by atomic absorption spectroscopy) and SIL (by SRID). The results, when analysed, suggested a reduction in SIL with emphasis on IgG in comparison with standard levels.

scholarly journals Risk Factors of Inadequate Bowel Preparation for Screening Colonoscopy

2021 ◽  
Vol 10 (12) ◽  
pp. 2740
Author(s):  
Efrat L. Amitay ◽  
Tobias Niedermaier ◽  
Anton Gies ◽  
Michael Hoffmeister ◽  
Hermann Brenner
Keyword(s):  
Risk Factors ◽  
Bowel Preparation ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Screening Colonoscopy ◽  
Cross Sectional ◽  
Factors Associated ◽  
Screening Practice ◽  
Abdominal Symptoms ◽  
Inadequate Bowel Preparation

The success of a colonoscopy in detecting and removing pre-cancerous and cancerous lesions depends heavily on the quality of bowel preparation. Despite efforts, 20–44% of colonoscopy participants have an inadequate bowel preparation. We aimed to assess and compare risk factors for inadequate bowel preparation and for the presence of advanced colorectal neoplasms in routine screening practice. In this cross-sectional study, among 8125 participants of screening colonoscopy in Germany with a comprehensive assessment of sociodemographic factors, lifestyle and medical history, we examined factors associated with inadequate bowel preparation and with findings of advanced neoplasms using adjusted log-binomial regression models. Among the identified risk factors assessed, three factors were identified that were significantly associated with inadequate bowel preparation: age ≥ 70 years (adjusted prevalence ratios, aPR, 1.50 95%CI 1.31–1.71), smoking (aPR 1.29 95%CI 1.11–1.50) and abdominal symptoms (aPR 1.14 95%CI 1.02–1.27). The same risk factors were also associated with the prevalence of advanced neoplasms in our study (aPR 1.72, 1.62 and 1.44, respectively). The risk factors associated with inadequate bowel preparation in this study were also associated with a higher risk for advanced neoplasms. Inadequate bowel preparation for colonoscopy might lead to missed colorectal cancer (CRC) precursors and the late diagnosis of CRC. People at high risk of advanced neoplasms are in particular need of enhanced bowel preparation.

scholarly journals Cross sectional study on the prevalence of polypharmacy and potentially inappropriate medications among elderly patients in a tertiary care centre in central Kerala

2021 ◽  
Vol 8 (3) ◽  
pp. 1415
Author(s):  
Jubina Bency Anthoorathodi ◽  
Aqueen Joju ◽  
Ann Mereena Reji ◽  
Anupama Pallivalappil Asokan ◽  
Anzeem Naseem ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Clinical Care ◽  
Inappropriate Medication ◽  
Cross Sectional Study ◽  
Health Concern ◽  
Potentially Inappropriate Medication ◽  
Potentially Inappropriate Medications ◽  
Sectional Study ◽  
Cross Sectional

Background: Polypharmacy or the concurrent use of multiple medications, is on the rise, especially in the elderly population as they suffer from multiple co-morbidities. Polypharmacy has been reported to increase the risks for inappropriate medication intake. Objectives: The aim was to investigate the prevalence of polypharmacy and usage of potentially inappropriate medication using Beer’s criteria and to find out the various risk factors of polypharmacy in hospitalised elderly.Methods: A cross sectional study was done in patients aged 60 years and above using a pre designed semi structured questionnaire and from their case records to assess the pattern of polypharmacy by different socio-demographic characteristics and also to found out the risk factors of polypharmacy.Results: 50 patients aged 60 and above were involved in our study out of which, 46% were females and 54% were males. Mean age of our study population was 71.5±8.3. Among them, 30 were hypertensive, 27 were diabetic, 9 of them had dyslipidaemia and 8 of them had coronary artery disease Mean number of medication use was 5.1±4.1. Polypharmacy was observed in 42% of the patients. 20% patients received potentially inappropriate drugs from Beer’s list. We also found significant association of polypharmacy with diabetes mellitus and hypertension.Conclusions: The present study has shown polypharmacy and usage of potentially inappropriate medication as an emerging public health concern. Diabetes mellitus and hypertension were found to be risk factors of polypharmacy. Deprescription should be integrated into clinical care and prescribers need to be educated about Beers criteria and encouraged for rational prescription.

Evaluation of blood lead among painters of buildings and cars

2021 ◽  
pp. 074823372110427
Author(s):  
Ali Ghaffarian-Bahraman ◽  
Alireza Taherifard ◽  
Abbas Esmaeili ◽  
Hassan Ahmadinia ◽  
Mohsen Rezaeian
Keyword(s):  
Lead Level ◽  
Blood Lead ◽  
Absorption Spectrometry ◽  
Cross Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Blood Samples ◽  
Low Concentrations ◽  
The Mean ◽  
Structured Questionnaire

Exposure to lead-based paints is a major threat to the health of painters. This study aimed to evaluate the blood concentration of lead (Pb) in painters of buildings and cars. The present study was a cross-sectional study in which a semi-structured questionnaire was used to collect the socio-demographic information. Lead concentration in blood samples was determined using the atomic absorption spectrometry method. A total of 32 male painters were selected based on inclusion criteria. The mean blood lead level (BLL) in the painters was 8.1 ± 4.93 μg/dL. Pb levels in car and building painters were 9.42 ± 5.5 μg/dL and 6.7 ± 1.85 μg/dL, respectively. Pb concentration in none of the blood samples was more than 30 μg/dL. The prevalence of BLL ≥ 5 μg/dL and BLL ≥ 10 μg/dL was 97% and 19%, respectively. According to the findings, the rate of BLL among car painters was higher than building painters. Considering the presence of Pb in all blood samples, it seems necessary to increase the awareness of painters about the adverse effects of lead exposure even in low concentrations. However, the sample size in this study was small and more investigations are required in this regard.

scholarly journals Lameness in Sheltered Cows and Its Association with Cow and Shelter Attributes

Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 360 ◽  
Author(s):  
Arvind Sharma ◽  
Clive J. C. Phillips
Keyword(s):  
Risk Factors ◽  
Body Condition ◽  
Body Condition Score ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Joint Injuries ◽  
Condition Score ◽  
Carpal Joint ◽  
Associated Risk Factors

The sheltering of old, unproductive and abandoned cows in traditional cow shelters, known as gaushalas, has been practiced in India since ancient times. Cows are kept in these shelters until they die of natural causes. The welfare of the cows in these shelters was assessed through a cross-sectional study of 54 cow shelters in six states of India. A total of 1620 cows were examined to assess the prevalence of lameness in these cows, and the associated risk factors for lameness were identified through the measurement of animal-based and resource-based welfare indicators. The overall lameness prevalence was 4.2%. The majority (86%) had mild to moderate hock joint swellings but no or only mild carpal joint injuries. Approximately one-half had mild to moderate hock joint hair loss and most were free of hock joint ulcerations. Claw overgrowth was present in almost one half of the cows. Lameness prevalence was positively correlated with coat dirtiness, hock and carpal joint lesions, diarrhea and claw overgrowth scores. In a multivariate analysis, lameness prevalence increased as the Body Condition Score (BCS) decreased and was associated with increased udder dirtiness, the ulceration of the hock joint, carpal joint injuries and claw overgrowth. Resource-based indicators measured at the shelter level suggested that an absence of bedding in the sheds and an increase in the gradient of the shed flooring increased lameness. Addressing the principle risk factors identified for lameness in the sheltered cows (low body condition, dirty udders, lesions on the hock and carpal joints, overgrown claws, and a steep floor gradient) may help to reduce this serious animal welfare problem.

scholarly journals Arterial hypertension in the elderly accompanied in primary care: profile and associated factors

2019 ◽  
Vol 23 (2) ◽  
Author(s):  
Breno de Sousa Santana ◽  
Bárbara Soares Rodrigues ◽  
Marina Morato Stival ◽  
Cris Renata Grou Volpe
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Strong Association ◽  
Federal District ◽  
The Elderly ◽  
Pressure Control ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Elderly Hypertensive

Abstract Objective: to analyze blood pressure control in elderly hypertensives accompanied by a Basic Health Unit of the Federal District, determining the sociodemographic profile and the associated risk factors. Method: this is a cross-sectional study with 133 elderly hypertensive patients. Variables related to sociodemographic factors, life habits, clinical factors and adherence to drug therapy were evaluated through the application of semistructured instruments and validated scales. Results with p <0.05 were considered significant. Results: the elderly presented controlled blood pressure (56.4%) predominantly. The majority of the participants were female and women also had a higher rate of uncontrolled blood pressure (86.2%). Older age was associated with higher blood pressure values (p = 0.031). Alcoholism (p = 0.020) and mean body mass index of 33.0 (p <0.000) were factors associated with hypertension adherence to therapy had more controlled values of systolic and diastolic blood pressure. Conclusion and implications for the practice: it was verified that there is a strong association between the risk factors discussed and the lack of control of the blood pressure of elderly hypertensive, especially with regard to advanced age, alcoholism, obesity and overweight, and it is necessary to reorient the planning and strategies of promotion of health and prevention of diseases directed at the elderly hypertensive in the scope of primary health care.

scholarly journals Examining the relationship between blood lead level and stunting, wasting and underweight- A cross-sectional study of children under 2 years-of-age in a Bangladeshi slum

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0197856 ◽  
Author(s):  
Mohammad Jyoti Raihan ◽  
Emily Briskin ◽  
Mustafa Mahfuz ◽  
M. Munirul Islam ◽  
Dinesh Mondal ◽  
...  
Keyword(s):  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

scholarly journals Environmental Lead Exposure, Catalase Gene, and Markers of Antioxidant and Oxidative Stress Relation to Hypertension: An Analysis Based on the EGAT Study

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Jintana Sirivarasai ◽  
Sukhumpun Kaojarern ◽  
Suwannee Chanprasertyothin ◽  
Pachara Panpunuan ◽  
Krittaya Petchpoung ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Oxidative Stress Marker ◽  
Blood Levels ◽  
Cross Sectional ◽  
Cat Gene

Lead has been linked to the development of hypertension via oxidative stress. Catalase plays an important role in the disposal of hydrogen peroxide in erythrocyte and its activity was determined by CAT gene. The aims of this study were to investigate (1) the association between blood levels of antioxidant markers such as catalase, superoxide dismutase, glutathione, glutathione peroxidase, oxidative stress-marker (malondialdehyde), and blood lead level and (2) the influence of genetic polymorphism of CAT gene (rs769217) on change in blood pressure in general population of EGAT study project. This is a cross-sectional study of 332 normotensive, 432 prehypertensive, and 222 hypertensive male subjects. Hypertensive subjects had significantly higher blood lead level (5.28 μg/dL) compared to normotensive (4.41 μg/dL) and prehypertensive (4.55 μg/dL) subjects (P<0.05). These significant findings are also found in MDA levels. Moreover, individuals with TT genotype in hypertensive group had significantly higher blood lead and MDA levels (6.06 μg/dL and 9.67 μmol/L) than those with CC genotype (5.32 μg/dL and 8.31 μmol/L,P<0.05). Our findings suggested that decreased blood catalase activity in this polymorphism together with low level lead exposure induced lipid peroxidation may be responsible for hypertension.

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