scholarly journals The Relationships between Leptin, Genotype, and Chinese Medicine Body Constitution for Obesity

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Hsiang-I. Hou ◽  
Hsing-Yu Chen ◽  
Jang-Jih Lu ◽  
Shih-Cheng Chang ◽  
Hsueh-Yu Li ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Personal Information ◽  
Uncoupling Protein ◽  
The Body ◽  
High Expression ◽  
Nucleotide Polymorphisms ◽  
Severe Problem ◽  
Yin Deficiency ◽  
Body Constitution

Background and Purpose. Obesity is a widespread and increasingly severe problem worldwide. Several single nucleotide polymorphisms (SNPs) associated with obesity have been identified, reflecting metabolic disorders between the environment, diet, and body constitution. Traditional Chinese medicine body constitution (TCMBC) plays a central role in the classification of human body constitution from the viewpoint of traditional Chinese medicine (TCM). This study aims at exploring the relations between TCMBC and obesity-related biochemistry profiles and SNPs. Methods. The adults with body mass index (BMI) more than 27 kg/m2 were enrolled in the study. General personal information, physical condition, TCMBC, biochemical, and SNPs were collected for eligible subjects. The body constitution questionnaire (BCQ) was used to evaluate the relationships between TCMBC tendency, biochemical values, and obesity-related SNPs. Results. Obesity patients tended to have a yin deficiency constitution (YinDC) (n = 33, 66.0%); however, TCMBC in combination is not uncommon (30 subjects with more than two TCMBC in combination). For biochemical profiles, leptin was higher among patients with yang deficiency constitution (YangDC) (YangDC versus non-YangDC: 29.7 ± 24.8 versus 15.9 ± 9.9, P = 0.020 ) and YinDC (YinDC versus non-YinDC: 28.8 ± 23.5 versus 14.4 ± 9.6, P = 0.020 ). The leptin level was highest among YangDC subjects. Higher leptin was found among subjects with three-combined TCMBC than balanced TCMBC subjects who were not inclined to any of three TCMBC. For obesity-related SNPs, the adrenergic receptor beta-3 (ADRB3) gene tended to be high expression among YangDC (YangDC versus non-YangDC: 89.7% versus 71.4%, P = 0.091 ) and uncoupling protein 1 (UCP1) tended to be high expression among phlegm-stasis constitution (PSC) (PSC versus non-PSC: 37.9% versus 9.5%, P = 0.052 ). Conclusions. The relationships between TCMBC, leptin, and SNPs present alternative viewpoints about TCMBC and could be used as a guide to treat obese patients.

scholarly journals Reduced MLH3 Expression in the Syndrome of Gan-Shen Yin Deficiency in Patients with Different Diseases

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Juan Du ◽  
Maofeng Zhong ◽  
Dong Liu ◽  
Shufang Liang ◽  
Xiaolin Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Roc Analysis ◽  
Primary Liver Cancer ◽  
The Body ◽  
Metabolic Characteristics ◽  
Yin Deficiency ◽  
Body Constitution ◽  
Deficiency Group ◽  
The Relationship

Traditional Chinese medicine formulates treatment according to body constitution (BC) differentiation. Different constitutions have specific metabolic characteristics and different susceptibility to certain diseases. This study aimed to assess the characteristic genes of gan-shen Yin deficiency constitution in different diseases. Fifty primary liver cancer (PLC) patients, 94 hypertension (HBP) patients, and 100 diabetes mellitus (DM) patients were enrolled and classified into gan-shen Yin deficiency group and non-gan-shen Yin deficiency group according to the body constitution questionnaire to assess the clinical manifestation of patients. The mRNA expressions of 17 genes in PLC patients with gan-shen Yin deficiency were different from those without gan-shen Yin deficiency. However, considering all patients with PLC, HBP, and DM, only MLH3 was significantly lower in gan-shen Yin deficiency group than that in non-gen-shen Yin deficiency. By ROC analysis, the relationship between MLH3 and gan-shen Yin deficiency constitution was confirmed. Treatment of MLH3 (−/− and −/+) mice with Liuweidihuang wan, classical prescriptions for Yin deficiency, partly ameliorates the body constitution of Yin deficiency in MLH3 (−/+) mice, but not in MLH3 (−/−) mice. MLH3 might be one of material bases of gan-shen Yin deficiency constitution.

scholarly journals Constitutions of Deficiency and Stasis of Traditional Chinese Medicine and Related Factors among Middle-Aged Women in Taiwan

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Ping-Ho Chen ◽  
Sheng-Miauh Huang ◽  
Jerry Cheng-Yen Lai ◽  
Pei-Jung Yu
Keyword(s):  
Logistic Regression ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Multiple Logistic Regression Analysis ◽  
The Body ◽  
Research Database ◽  
Middle Aged ◽  
Related Factors ◽  
Yin Deficiency ◽  
Younger Age

Background. Traditional Chinese medicine (TCM) appears to be the common therapy in middle-aged women. The constitution serves as a guide for TCM treatment. However, little is known about the constitution and related factors in middle-aged women. The objectives of this study were to describe the yang-deficiency, yin-deficiency, and stasis constitutions in middle-aged women. Demographic and health factors related to yang deficiency, yin deficiency, and stasis were also examined. Methods. A total of 1,000 women aged 40–65 years were selected from 2009 through 2018 using random sampling from the Taiwan Biobank Research Database in Taiwan. Yang-deficiency, yin-deficiency, and stasis were assessed using the body constitution questionnaire. Multiple logistic regression analysis was used to identify factors associated with constitution in deficiency or stasis. Results. The proportions of middle-aged women who had the constitution in yang-deficiency, yin-deficiency, and stasis were 29.7%, 21.7%, and 17.7%, respectively. The result of binary logistic regression showed that current menstruation, abnormal spirometry, and education level were predictive factors of yang deficiency. Women with younger age, abnormal spirometry, or a vegetarian diet had a significantly associated yin deficiency. Younger age, abnormal spirometry, and coffee habit were predictors of stasis. Conclusions. Middle-aged women in Taiwan with abnormal spirometry had a higher risk for deficiency or stasis constitutions, especially for those younger than 56 years. Healthcare providers should learn patients’ constitutions and provide appropriate advice, referring them to safe providers of their desired method.

EFFECT OF CHINESE MEDICINE ON MUSCLE FATIGUE OF ATHLETES

2021 ◽  
Vol 27 (7) ◽  
pp. 706-709
Author(s):  
Ma Jin
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Muscle Fatigue ◽  
T Test ◽  
The Body ◽  
Good Effect ◽  
Control Group ◽  
Exercise Fatigue ◽  
Experimental Group ◽  
Paired T Test

ABSTRACT Introduction: Traditional Chinese medicine has a very good effect on the treatment of exercise fatigue. However, if it is not handled actively and effectively, it can cause serious adverse effects on the body and lead to many diseases. Objective: To study the effect of TCM diagnosis and treatment on athletes’ exercise-induced muscle fatigue. Methods: The results of the study were analyzed by comparing the experimental data in the experimental group and the control group. Results: A paired t test was conducted on the experimental results of the experimental intervention group and the data of the control group. It was found that regardless of individuals being male or female, the paired t test results of the experimental group and the data of the control group were all P < 0.05, showing significant differences in the paired data. Conclusions: In the experiment, all the treatment methods of traditional Chinese medicine had an obvious effect in the treatment of exercise fatigue, and reduced the recovery time of exercise fatigue at different degrees. Contrastive analysis shows that traditional Chinese medicine is effective in the treatment of exercise fatigue. Level of evidence II; Therapeutic studies - investigation of treatment results.

Traditional Chinese Medicine Typing of Affective Disorders and Treatment

1994 ◽  
Vol 22 (03n04) ◽  
pp. 321-327 ◽  
Author(s):  
Liang-dong Zhang ◽  
Ya-li Zhang ◽  
Shang-han Xu ◽  
Gang Zhou ◽  
Shu-bai Jin
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Affective Disorders ◽  
Marked Improvement ◽  
Yin Deficiency ◽  
In Fire

According to the theory of Traditional Chinese Medicine (TCM), 50 patients with affective disorders were typed into the categories of depressed liver resulting in fire, mild Yang deficiency and mild Yin deficiency and were treated with Xiao Yao San Jia Wei. The results are 26 patients with marked improvement, 17 patients with improvement and 7 patients with no improvement.

Development of Rapid Advice Guidelines for the Treatment of Coronavirus Disease 2019 with Traditional Chinese Medicine

2020 ◽  
Vol 48 (07) ◽  
pp. 1511-1521
Author(s):  
Ning Liang ◽  
Huizhen Li ◽  
Jingya Wang ◽  
Liwen Jiao ◽  
Yanfang Ma ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Observational Studies ◽  
The Body ◽  
Assessment Development ◽  
Evidence Collection ◽  
Novel Coronavirus ◽  
Grade Methodology ◽  
Evidence Based Guidelines

The worldwide spread of the 2019 novel coronavirus has become a profound threat to human health. As the use of medication without established effectiveness may result in adverse health consequences, the development of evidence-based guidelines is of critical importance for the clinical management of coronavirus disease (COVID-19). This research presents methods used to develop rapid advice guidelines on treating COVID-19 with traditional Chinese medicine (TCM). We have followed the basic approach for developing WHO rapid guidelines, including preparing, developing, disseminating and updating each process. Compared with general guidelines, this rapid advice guideline is unique in formulating the body of evidence, as the available evidence for the treatment of COVID-19 with TCM is from either indirect or observational studies, clinical first-hand data together with expert experience in patients with COVID-19. Therefore, our search of evidence not only focuses on clinical studies of treating COVID-19 with TCM but also of similar diseases, such as pneumonia and influenza. Grading of recommendations assessment, development and evaluation (GRADE) methodology was adopted to rate the quality of evidence and distinguish the strength of recommendations. The overall certainty of the evidence is graded as either high, moderate, low or very low, and to give either “strong” or “weak” recommendations of each TCM therapy. The output of this paper will produce the guideline on TCM for COVID-19 and will also provide some ideas for evidence collection and synthesis in the future development of rapid guidelines for COVID-19 in TCM as well as other areas.

Conjuctivitis Sicca: A Comparison of Traditional Chinese and Western Medical Symptoms

1994 ◽  
Vol 12 (2) ◽  
pp. 88-92 ◽  
Author(s):  
Johannes Nepp ◽  
A Wedrich
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Medical Doctors ◽  
Autonomic Nervous ◽  
Yin Deficiency ◽  
Tcm Syndrome ◽  
Medical Symptoms ◽  
Conjunctivitis Sicca

In traditional Chinese medicine (TCM) three syndromes are said to be associated with conjunctivitis sicca: Liver-Yin deficiency, Liver-Yang excess and Liver fire. The diagnosis of one of these syndromes requires the use of a specific combination of points for acupuncture. We used an extensive questionnaire of autonomic nervous system disturbances to suggest points that should be treated on a western medical basis. This prospective study was performed to answer two questions: i. Is it possible to associate the complaints of our patients with a TCM syndrome? ii. Is there any difference between the results using a TCM combination of points and those selected with our western method? Thirty seven patients with conjunctivitis sicca were enrolled in the study and asked to complete two questionnaires. In one, autonomic nervous system complaints were evaluated; in the second, the symptoms of the three relevant TCM syndromes were specifically asked for. The results of both questionnaires were compared. Our “western medical” combination of points for therapy consisted of local points, and points related to the autonomic nervous system complaints and to the five Chinese elements. In total we recorded 29 different symptoms associated with conjunctivitis sicca. According to the TCM questionnaire, 21 patients had a deficit of Liver-Yin, 5 had a Liver-Yang excess and 10 suffered from Liver fire. One patient had symptoms of Liver-Yin and Liver-Yang. Yet all patients had symptoms of more than one Chinese syndrome. Only 4 out of 37 patients seemed to belong clearly to only one TCM syndrome. So the evaluation of symptoms according to the TCM system proved to be inadequate compared with the western “autonomic” system. Points for therapy resulting from the western system were similar to the points proposed by the TCM system. We conclude that the points proposed by both methods are similar for the treatment of conjunctivitis sicca, but we believe that for western medical doctors it is easier to find a successful combination of points with the western method asking about complaints of the autonomic nervous system.

The integration of traditional Chinese medicine and Western medicine

2003 ◽  
Vol 11 (2) ◽  
pp. 225-235 ◽  
Author(s):  
CHEN KEJI ◽  
XU HAO
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Western Medicine ◽  
Chinese Philosophy ◽  
Medical Science ◽  
Integrated Approach ◽  
The Body ◽  
Theoretical Research ◽  
Human Beings ◽  
The Future

Traditional Chinese Medicine (TCM) is one of the world's oldest medical systems, having a history of several thousands of years. It is a system of healing based upon the Chinese philosophy of the correspondence between nature and human beings. Its theories refer to yin and yang, the Five Elements, zang-fu, channels-collaterals, qi, blood, body fluid, methods of diagnosis, the differentiation of symptom-complexes, etc. TCM has two main features: a holistic point of view and treatment according to a differentiation of syndromes. The therapeutic methods of TCM involve different approaches, such as acupuncture, moxibustion, tuina bodywork, herbal medicine and qi gong, in order to allow the body to heal itself in a natural way. Western medicine was first introduced into China from the middle of the 17th century. During the first two centuries several different views, related to the future of TCM and the relation between TCM and Western medicine, emerged. Some advocated ‘complete westernization’ of Chinese medicine, others were in favour of keeping it intact, whereas again others recommended the ‘digestion and assimilation of TCM and Western medicine’. Nowadays, more and more people realize that each of the two medical traditions has its own merits and advise that the two systems should benefit from each other's strong points. We offer an argument for integrating Western medicine with TCM. In the 20th century China has maintained and developed three kinds of medical science, that is, TCM, Western medicine, and ‘integrated medicine’. Much has been achieved in clinical, experimental and theoretical research. The development of any science can be furthered by cross-fertilization based on absorption and fusion of whatever useful theory and experience. It is our dream that, in the future, diverse modalities – including TCM, Western medicine and possibly other variants – can work in conjunction with each other as part of a unified team rather than in competition. This integrated approach will ultimately lead to safer, faster and more effective health care.

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