scholarly journals Pancreatic Injury in Patients with SARS-Cov-2 (COVID-19) Infection: A Retrospective Analysis of CT Findings

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Gabriela Grusova ◽  
Radan Bruha ◽  
Bianka Bircakova ◽  
Matej Novak ◽  
Lukas Lambert ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Fluid Collection ◽  
Laboratory Data ◽  
Elevated Serum ◽  
Pancreatic Injury ◽  
Orotracheal Intubation ◽  
Matched Cohort ◽  
Age And Gender ◽  
Pulmonary Parenchyma ◽  
And Gender

Objective. To determine the association between COVID-19 infection and peripancreatic changes on CT as a sign of acute pancreatic injury. Methods. Retrospective analysis of CT examinations in patients with confirmed COVID-19 infection yielded 103 instances. An age- and gender-matched cohort of patients without COVID-19 was found. CT examinations were evaluated for peripancreatic stranding or edema, fluid collection, or necrosis, without any other explanation. Depicted pulmonary parenchyma was evaluated for possible COVID-19-related changes. Clinical and laboratory data were retrieved from the clinical database. Results. Peripancreatic fat stranding ( n = 8 ) or fluid collection ( n = 2 ) without any other cause was found in 10 (10%) patients. Abdominal complaints were reported in 4 (40%) patients. Elevated serum amylase or lipase levels were documented in 5 (50%) patients who also satisfied the diagnostic criteria for acute pancreatitis. From the study sample of 103 patients with COVID-19, pulmonary parenchyma was depicted in 102 (99%), and from these, 57 (55%) had an evidence of pulmonary changes compatible with COVID-19 pneumonia. This proportion was not significantly different between patients with and without peripancreatic changes ( p = 0.35 ). In the matched cohort, we found peripancreatic changes in 2 (2%, p = 0.033 ) patients. Patients with pancreatic injury and elevated amylase levels were more likely to require orotracheal intubation (35% vs. 12%, p = 0.021 ). Conclusions. We showed that the prevalence of peripancreatic stranding or fluid collection is higher in patients diagnosed with COVID-19 infection compared to an age- and gender-matched cohort. Patients with pancreatic injury and elevated amylase levels are more likely to require orotracheal intubation. Our findings corroborate the link between COVID-19 infection and pancreatic injury from the perspective of imaging.

scholarly journals Reference intervals for serum lipids and prevalence of dyslipidaemia in 6–12-year-old children: The Health Oriented Pedagogical Project (HOPP)

2018 ◽  
Vol 46 (21_suppl) ◽  
pp. 21-27 ◽  
Author(s):  
Martin Frank Strand ◽  
Per Morten Fredriksen ◽  
Ole Petter Hjelle ◽  
Morten Lindberg
Keyword(s):  
Total Cholesterol ◽  
Serum Lipids ◽  
Venous Blood ◽  
Elevated Serum ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Reference Intervals ◽  
Age And Gender ◽  
Norwegian Population ◽  
And Gender

Aims: Elevated serum lipid concentrations in childhood are thought to be risk factors for the development of cardiovascular disease later in life. The present study aims to provide age- and gender-related reference intervals for total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, and non-HDL cholesterol in healthy school children. We also investigated the prevalence of dyslipidaemia using the published criteria for these biomarkers. Methods: Venous blood and anthropometric data were collected from 1340 children in the HOPP study, aged between 6 and 12 years. Age- and gender-related reference intervals (2.5th and 97.5th percentiles) were established according to the IFCC recommendations, using the software RefVal 4.10. Results: Gender differences were observed for total cholesterol and non-HDL cholesterol, but not for HDL cholesterol. Age differences were observed for total cholesterol. The reference intervals were in the range of 3.1–5.9 mmol/L for total cholesterol, 1.0–2.4 mmol/L for HDL cholesterol and 1.4–4.2 mmol/L for non-HDL cholesterol. Dyslipidaemia prevalence was as follows: increased TC 9.6%, decreased HDL 1.6%, and increased non-HDL 5.6%. Conclusions: Age- and gender-related reference intervals in a Norwegian population are similar to those reported in other countries. The prevalence of dyslipidaemia among Norwegian children is significant, emphasising the importance of appropriate reference intervals in clinical practice.

Thirty-day readmissions in multiple sclerosis: An age and gender-based US national retrospective analysis

2019 ◽  
Vol 31 ◽  
pp. 41-50 ◽  
Author(s):  
Smit Patel ◽  
Pooja SirDeshpande ◽  
Rupak Desai ◽  
Ninad Desai ◽  
Hemanshi Mistry ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Retrospective Analysis ◽  
Age And Gender ◽  
Gender Based ◽  
And Gender

scholarly journals Relationship of Timings and Outcome of Tracheostomy Among Patients Requiring Prolonged Mechanical Ventilation

2019 ◽  
Vol 10 (1) ◽  
pp. 12-16
Author(s):  
Muhammad Asim Shafique ◽  
Muhammad Amir Nadeem ◽  
Muhammad Afzal
Keyword(s):  
Mechanical Ventilation ◽  
Prolonged Mechanical Ventilation ◽  
Secondary Data ◽  
Orotracheal Intubation ◽  
Age And Gender ◽  
Good Outcome ◽  
Male Patients ◽  
And Gender ◽  
Relationship Of ◽  
The Relationship

Objective: To assess the indications of tracheostomy among patients requiring prolonged mechanical ventilation and to observe the relationship of the timings and outcome of tracheostomy with age and gender. Study Design and Setting: It was a descriptive study conducted at intensive care unit (ICU) of Department of Otorhinolaryngology at Bahawal Victoria Hospital from January 2017 to December 2018. Methodology: Secondary data was collected with the help of charts of ICU patients in which elective tracheostomy was done to replace orotracheal intubation for mechanical ventilation. Inclusion and exclusion criteria were designed. Clinical record was reviewed for the assessment of indications of the procedure (medical or surgical) along with age and gender distribution. The timing of tracheostomy in these patients with its outcome in terms of decannulation and weaning were recorded. Proforma was used to enter the findings. Finally results were obtained and assessed on SPSS Version 23. Results: Out of total 551 tracheostomies 42(7.6%) were indicated for the patients of ICU requiring prolonged mechanical ventilation. From the 42 mechanical ventilated patients majority had Guillain-Barre syndrome (GBS) 20(47.6%). Twenty six patients were adults (61.9%) and sixteen were children (38%).Twenty four were male patients (57.1%) and eighteen were females (42.8%). The timing of tracheostomy among majority of the patients (40) was from 7-10 days, with mean of 9th day with good outcome. Only two patients who underwent tracheostomy after two weeks had to face poor outcome (failed decannulation, late weaning) (4.7%). Conclusion: Neuroparalytic lesions were the common indication among the patients requiring prolonged mechanical ventilation with tracheostomy. Tracheostomy if performed earlier in such patients carries good outcome

scholarly journals Retrospective analysis of the frequency of detection of cystic lesions of the maxillofacial area and neck

2021 ◽  
Vol 106 (2) ◽  
pp. 44-47
Author(s):  
H. Krynychnykh ◽  
◽  
S. Shuvalov ◽  
Keyword(s):  
Head And Neck ◽  
Key Words ◽  
Retrospective Analysis ◽  
Cystic Lesions ◽  
Maxillofacial Region ◽  
Age And Gender ◽  
Clinical Hospital ◽  
Dental Patients ◽  
And Gender

Abstract. The frequency of detection of cystic lesions of the head and neck in dental patients of the maxillofacial department of the Vinnitsya Regional Clinical Hospital named after N.I. Pirogov on the basis of a retrospective analysis of the hospital’s archival materials for five years was determined. The structure of the cysts of the maxillofacial region with the correlation of age and gender indicators is described. Key words: frequency, cyst, retrospective analysis, correlation.

Retrospective Analysis of Esophageal Food Impaction: Differences in Etiology By Age and Gender

2005 ◽  
Vol 61 (5) ◽  
pp. AB131
Author(s):  
Kathryn R. Byrne ◽  
Kristen Hilden ◽  
Kristen L. Thomas ◽  
Panagiotis H. Panagiotakis ◽  
Kathryn A. Peterson ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Food Impaction ◽  
Age And Gender ◽  
Esophageal Food Impaction ◽  
And Gender

scholarly journals Risk Factors for Recurrent Anterior Shoulder Instability after Arthroscopic Stabilization in Adolescent Athletes

2019 ◽  
Vol 7 (7_suppl5) ◽  
pp. 2325967119S0034
Author(s):  
Timothy Cheng ◽  
Eric W. Edmonds ◽  
Tracey P. Bastrom ◽  
Andrew T. Pennock
Keyword(s):  
Risk Factors ◽  
Bone Loss ◽  
Matched Cohort ◽  
Arthroscopic Stabilization ◽  
Anterior Instability ◽  
Adolescent Athletes ◽  
Recurrent Instability ◽  
Age And Gender ◽  
And Gender ◽  
Skeletal Immaturity

Objectives: Arthroscopic stabilization has become the preferred surgery for adolescent athletes with anterior instability without significant bone loss. Although successful for most patients, 10-40% will experience recurrent instability. The purpose of the current study was to compare a consecutive series of patients who had failed an arthroscopic stabilization to an age and gender matched cohort of patients who had no evidence of recurrent instability with a goal of identifying risk factors for future instability. Methods: A retrospective review was undertaken of all patients undergoing an arthroscopic shoulder stabilization for anterior instability between 2009 and 2016. Patients over the age of 18 years and those with underlying syndromes affecting the musculoskeletal system were excluded. Two patient cohorts were identified: (1) Patients with recurrent instability (frank dislocations or subluxations) after their arthroscopic stabilization; (2) An age and gender matched cohort of patients with no recurrent instability at a minimum of 2 years follow-up from surgery. Patient demographic, injury, radiographic, and surgical variables were recorded. In particular, bone loss measurements were performed on both the glenoid and humerus, and Hill-Sachs lesions were classified as “on-track” or ”off-track”. Variables at p<0.10 on univariate analysis were entered into a binary logistic multivariate regression analysis. Results: 35 patients were identified that failed an arthroscopic stabilization at a mean of 1.2 ± 1.0 years after their index surgery. A separate age and gender matched cohort of 35 patients was also identified with no symptoms of recurrent instability. Univariate analysis identified the following 4 risk factors for recurrent instability (glenoid bone loss > 10%, glenoid retroversion < 5◦, skeletal immaturity, and patients with more than one pre-surgical instability event). Collision sport participation, the presence and size of a Hill-Sachs deformity, and the glenoid track were not predictive of failure. Multivariate regression analysis revealed that loss of glenoid retroversion, skeletal immaturity, and a greater number of prior instability events best predicted future recurrence with two risk factors having a 3x increased risk and patients with all three risk factors having a 4x increased risk of recurrent instability after arthroscopic stabilization. Conclusion: Anterior glenoid bone loss, glenoid version, skeletal immaturity, and multiple pre-operative instability events are risk factors for failed arthroscopic stabilization in adolescent athletes with anterior instability. In the setting of multiple risk factors, patients and families should be counselled of the increased odds of surgical failure and other forms of surgical stabilization may need to be considered.

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