scholarly journals Review of Compounds and Pharmacological Effects of Delphinium

2020 ◽  
Vol 2020 ◽  
pp. 1-23
Author(s):  
Sitan Chen ◽  
Lijun Meng ◽  
Fatma M. El-Demerdash ◽  
Li Zhou ◽  
Syed Arif Hussian Rizvi ◽  
...  

Plants of Delphinium are herbal medicine used in the Tibet region with whole grass as a drug, which have the effects of analgesic, antibacterial, antipyretic, and anticancer. The main bioactive compounds are alkaloids, flavonoids, and sterols. This review summarized the compounds and pharmacological effects of Delphinium and provides a reference for further research on Delphinium.

2020 ◽  
Vol 26 ◽  
Author(s):  
Kondeti Ramudu Shanmugam ◽  
Bhasha Shanmugam ◽  
Gangigunta Venkatasubbaiah ◽  
Sahukari Ravi ◽  
Kesireddy Sathyavelu Reddy

Background : Diabetes is a major public health problem in the world. It affects each and every part of the human body and also leads to organ failure. Hence, great progress made in the field of herbal medicine and diabetic research. Objectives: Our review will focus on the effect of bioactive compounds of medicinal plants which are used to treat diabetes in India and other countries. Methods: Information regarding diabetes, oxidative stress, medicinal plants and bioactive compounds were collected from different search engines like Science direct, Springer, Wiley online library, Taylor and francis, Bentham Science, Pubmed and Google scholar. Data was analyzed and summarized in the review. Results and Conclusion: Anti-diabetic drugs that are in use have many side effects on vital organs like heart, liver, kidney and brain. There is an urgent need for alternative medicine to treat diabetes and their disorders. In India and other countries herbal medicine was used to treat diabetes. Many herbal plants have antidiabetic effects. The plants like ginger, phyllanthus, curcumin, aswagandha, aloe, hibiscus and curcuma showed significant anti-hyperglycemic activities in experimental models and humans. The bioactive compounds like Allicin, azadirachtin, cajanin, curcumin, querceitin, gingerol possesses anti-diabetic, antioxidant and other pharmacological properties. This review focuses on the role of bioactive compounds of medicinal plants in prevention and management of diabetes. Conclusion: Moreover, our review suggests that bioactive compounds have the potential therapeutic potential against diabetes. However, further in vitro and in vivo studies are needed to validate these findings.


2020 ◽  
Vol 20 (28) ◽  
pp. 2520-2534
Author(s):  
He Huang ◽  
Chuanjun Song ◽  
Junbiao Chang

: Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.


Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 300
Author(s):  
Amine Nekkaa ◽  
Akila Benaissa ◽  
Fabrice Mutelet ◽  
Laetitia Canabady-Rochelle

Rhamnus alaternus, is a wild-growing shrub, belonging to the Rhamnaceae family. Widely distributed in the Mediterranean basin, R. alaternus is used in the usual medicine in numerous countries, mostly Tunisia, Algeria, Morocco, Spain, France, Italy, and Croatia. A large number of disorders—including dermatological complications, diabetes, hepatitis, and goiter problems—can be treated by the various parts of R. alaternus (i.e., roots, bark, berries, and leaves). Several bioactive compounds were isolated from R. alaternus, including flavonoids, anthocyanins, and anthraquinones, and showed several effects such as antioxidant, antihyperlipidemic, antigenotoxic, antimutagenic, antimicrobial, and antiproliferative. This review summarizes the updated information concerning the botanical description, distribution, extraction processes applied on R. alaternus, and its ethnopharmacology, toxicity, phytochemistry, and pharmacological effects.


Planta Medica ◽  
2000 ◽  
Vol 66 (7) ◽  
pp. 607-611 ◽  
Author(s):  
Chizu Taniguchi ◽  
Masato Homma ◽  
Osamu Takano ◽  
Toshihiko Hirano ◽  
Kitaro Oka ◽  
...  

2017 ◽  
Vol 4 (1) ◽  
pp. 42
Author(s):  
Ira Safitri ◽  
Inayah Inayah

Sapu Jagad (Isotoma longiflora (L) Presl.) plant has been empirically used as traditional medicine. Some studies showthat this plant has pharmacological effects as antibiotic, anticancer, and analgetic. It is of importance to conduct studyin finding out the safetiness of this plant as herbal medicine. Therefore, we conducted study to find out lethal dose ofits leaves on mice (Mus muculus) using acute toxicity test. Several doses have been given to certain groups to find outits effect including death. The extract has been given one time per oral. Then, we recorded the clinical signs and deathof mice until 14 days. The data was analyzed using probit analysis to measure LD50. This study shows that ethanolextract of Sapu Jagad leaves has LD50 12.610 mg/kgBW and toxicity of central nervous system proven by seizureending with death. As conclusion, this extract has toxicity especially to central nervous system.


Foods ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 973
Author(s):  
Lin-Lin Jiang ◽  
Xue Gong ◽  
Ming-Yue Ji ◽  
Cong-Cong Wang ◽  
Jian-Hua Wang ◽  
...  

Hyperuricemia is a common metabolic disease that is caused by high serum uric acid levels. It is considered to be closely associated with the development of many chronic diseases, such as obesity, hypertension, hyperlipemia, diabetes, and cardiovascular disorders. While pharmaceutical drugs have been shown to exhibit serious side effects, and bioactive compounds from plant-based functional foods have been demonstrated to be active in the treatment of hyperuricemia with only minimal side effects. Indeed, previous reports have revealed the significant impact of bioactive compounds from plant-based functional foods on hyperuricemia. This review focuses on plant-based functional foods that exhibit a hypouricemic function and discusses the different bioactive compounds and their pharmacological effects. More specifically, the bioactive compounds of plant-based functional foods are divided into six categories, namely flavonoids, phenolic acids, alkaloids, saponins, polysaccharides, and others. In addition, the mechanism by which these bioactive compounds exhibit a hypouricemic effect is summarized into three classes, namely the inhibition of uric acid production, improved renal uric acid elimination, and improved intestinal uric acid secretion. Overall, this current and comprehensive review examines the use of bioactive compounds from plant-based functional foods as natural remedies for the management of hyperuricemia.


2021 ◽  
Vol Volume 11 ◽  
pp. 1-14
Author(s):  
Nafaa Alzobaidi ◽  
Huma Quasimi ◽  
Nasr A Emad ◽  
Abdulsalam Alhalmi ◽  
Maaz Naqvi

KOVALEN ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 202-207
Author(s):  
Asniati ◽  
Muthmainnah

One of the herbal plants that have long been used as traditional herbal medicine by Central Sulawesi peoples is Mantalalu (Euphorbia hirta L). Central Sulawesi peoples used this Mantalalu to appendicitis medicine. The chemical compound contained in Mantalalu plant has a role in providing different pharmacology. A study was conducted about the chemical compound content Mantalalu plant (Euphorbia hirta L). The method of this research was boiling dried leave and wet leave of Mantalalu plant and phytochemical test including flavonoids tests, alkaloids tests, saponins tests, polyphenol, and tannin tests. The results of this research showed that the decoction of dried and wet leaf samples of Mantalalu plant contained flavonoid, polyphenol, tannin, and saponins bioactive compounds.


2016 ◽  
Vol 2 (1) ◽  
pp. 1212320 ◽  
Author(s):  
Hua Wei ◽  
Jing-Jing Zhu ◽  
Xiao-Qian Liu ◽  
Wei-Hong Feng ◽  
Zhi-Min Wang ◽  
...  

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