scholarly journals Central Sensitivity Is Associated with Poor Recovery of Pain: Prediction, Cluster, and Decision Tree Analyses

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Hayato Shigetoh ◽  
Masayuki Koga ◽  
Yoichi Tanaka ◽  
Shu Morioka

The process of pain recovery varies and can include the recovery, maintenance, or worsening of symptoms. Many cases of patients with pain show a tendency of recovering as predicted; however, some do not. The characteristics of cases that do not fit the prediction of pain recovery remain unclear. We performed cluster and decision tree analyses to reveal the characteristics in cases that do not fit the prediction of pain recovery. A total of 43 patients with musculoskeletal pain (nonoperative: 22 patients, operative: 13 patients) and central pain (brain disease: 5 patients, spinal cord disease: 3 patients) were included in this longitudinal study. Central sensitivity syndrome (CSS) outcome measures (Central Sensitisation Inventory), pain intensity-related outcome measures (Short-Form McGill Pain Questionnaire-2 (SFMPQ-2)), and cognitive-emotional outcome measures (Hospital Anxiety and Depression Scale and Pain Catastrophising Scale-4) of all patients were assessed at baseline and after 1-2 months. Regression analysis was used to calculate pain recovery prediction values. A hierarchical cluster analysis based on the predicted change of SFMPQ-2 and the observed change of SFMPQ-2 was used to extract subgroups that fit and those that do not fit pain recovery prediction. To extract the characteristics of subgroups that do not fit the prediction of pain recovery, a decision tree analysis was performed. The level of significance was set at 5%. In the results of cluster analysis, patients were classified into three subgroups. Cluster 1 was characterised by worse pain intensity from baseline, cluster 2 by pain, having recovered less and mildly than the predicted value, and Cluster 3 by a marked recovery of pain. In the results of the decision tree analysis, the CSI change was extracted as an indicator related to the classification of all clusters. Our findings suggest that the poor improvement of CSS is characteristic in cases that do not fit the prediction of pain recovery.

2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background: As it is less known about the prevalence and characteristics of pain in the patients with interstitial lung disease (ILD), this paper aims at determining the characteristics of the pain in the patients with ILD.Methods: Subjects with ILD and health controls with the matched ages and genders completed Short Form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory (BPI) Short Form to elicit the characteristics of the pain. The patients with ILD were also assessed through Pulmonary Function Test, Six Minutes Walking Test (6MWT), modified Medical Research Council Dyspnea Scale (mMRC) for state of the illness and measured health-related quality of life (HRQoL) by Short Form-36 (SF-36) and psychological associations by Hospital Anxiety and Depression Scale (HADS).Results: A total of 63 subjects with ILD and 63 healthy controls (HC) were recruited in our study. The prevalence of the pain was 61.9% in ILD versus 25.3% in HC (p=0.005) and the median score of the pain rank index (PRI) in ILD was higher than that in HC (P=0.014). Chest (46.1%) accounted for the highest of overall pain locations in subjects with ILD. Associated clinical factors for pain intensity in the patients with ILD included exposure history of risk factors of ILD, with a longer distance of 6MWD (≥250m), and a higher mMRC score (2-4). The patients with ILD and pain are more likely to suffer impaired HRQoL (P=0.0014) and psychological problems (P=0.0017, P=0.044).Conclusion: The pain is common in those with ILD and the pain intensity is associated with exposure history, 6MWD, and mMRC score. The patients with ILD and pain were possibly to suffer depression, anxiety, and impaired HRQoL.


2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background Less is known about the prevalence and characteristics of pain in interstitial lung disease (ILD) patients.To determine the characteristics of pain in ILD patients. Methods Participants with ILD and age, gender-matched, healthy controls completed short form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory short form(BPI) to elicit pain characteristics. ILD patients also had assessments of pulmonary function test, six minutes walking test (6MWT), modified medical research council dyspnea scale (mMRC) for state of the illness and measured health-related quality of life(HRQoL) by short form-36(SF-36)and psychological associations by hospital anxiety and depression scale(HADS). Results A total of 63 participants with ILD and 63 healthy controls(HC) were recruited in our study. The prevalence of pain was 61.9% in ILDs versus 25.3% in HC (p=0.005) and the median score of pain rank index (PRI) in ILDs was higher than in HC (P=0.014). Chest(46.1%) accounted for the highest of overall pain locations in participants with ILD. Associated clinical factors for pain intensity in ILD patients included younger age (<60 years), exposure history of ILD risk factors, longer distance of 6MWD(≥250m), higher mMRC score(2-4) and lower DLCo, % predicted(≤45%). ILD patients with pain are more likely to suffer impaired HRQoL(P=0.0014) and psychological problems(P=0.0017,P=0.044). Conclusion Pain is common in those with ILD and the pain intensity is associated with age, exposure history, 6MWD, mMRC score and DLCo, % predicted. ILD patients with pain have more possible to suffer depression, anxiety and impaired HRQoL.


Author(s):  
Wenzhong Zhu ◽  
Yabo Shang ◽  
Sitong He ◽  
Wen-Tsao Pan

In the age of the Internet economy, Internet enterprises have attracted tremendous public attention, especially in China. In this paper, data mining through regression analysis, grey relational analysis, decision tree analysis and cluster analysis is implemented to further study the relationship between corporate social responsibility (CSR) and corporate financial performance (CFP) of Internet enterprises in China. This study collects and analyzes data of 20 Internet enterprises in China from the year of 2011 to 2016 and draws the following conclusions: (1) the relationship between CSR and CFP of the Internet enterprises is negative; (2) from the stakeholder perspective, CSR to shareholders, creditors and government is positively related to CFP; CSR to customers, suppliers and employees is not positively related to CFP; (3) through decision tree analysis, it is found that what affects the overall CSR performance of the Internet enterprises the most is CSR to customers and suppliers, while what affects the CFP of the Internet enterprises the most is CSR to creditors; (4) through cluster analysis, 20 enterprises can be divided into three types. This study has theoretical, methodological, practical and educational implications for future related research, business practitioners and educational institutions.


2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background Less is known about the prevalence and characteristics of pain in interstitial lung disease (ILD) patients. To determine the characteristics of pain in ILD patients.Methods Participants with ILD and age, gender-matched, healthy controls completed short form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory short form(BPI) to elicit pain characteristics. ILD patients also had assessments of pulmonary function test, six minutes walking test (6MWT), modified medical research council dyspnea scale (mMRC) for state of the illness and measured health-related quality of life(HRQoL) by short form-36(SF-36)and psychological associations by hospital anxiety and depression scale(HADS).Results A total of 63 participants with ILD and 63 healthy controls(HC) were recruited in our study. The prevalence of pain was 61.9% in ILDs versus 25.3% in HC (p = 0.005) and the median score of pain rank index (PRI) in ILDs was higher than in HC (P = 0.014). Chest(46.1%) accounted for the highest of overall pain locations in participants with ILD. Associated clinical factors for pain intensity in ILD patients included younger age (< 60 years), exposure history of ILD risk factors, longer distance of 6MWD(≥ 250 m), higher mMRC score(2–4) and lower DLCo, % predicted(≤ 45%). ILD patients with pain are more likely to suffer impaired HRQoL(P = 0.0014) and psychological problems(P = 0.0017,P = 0.044).Conclusion Pain is common in those with ILD and the pain intensity is associated with age, exposure history, 6MWD, mMRC score and DLCo, % predicted. ILD patients with pain have more possible to suffer depression, anxiety and impaired HRQoL.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background As it is less known about the prevalence and characteristics of pain in the patients with interstitial lung disease (ILD), this paper aims at determining the characteristics of the pain in the patients with ILD. Methods Subjects with ILD and health controls with the matched ages and genders completed Short Form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory (BPI) Short Form to elicit the characteristics of the pain. The patients with ILD were also assessed through Pulmonary Function Test, Six Minutes Walking Test (6MWT), modified Medical Research Council Dyspnea Scale (mMRC) for state of the illness and measured health-related quality of life (HRQoL) by Short Form-36 (SF-36) and psychological associations by Hospital Anxiety and Depression Scale (HADS). Results A total of 63 subjects with ILD and 63 healthy controls (HC) were recruited in our study. The prevalence of the pain was 61.9% in ILD versus 25.3% in HC (P = 0.005) and the median score of the pain rank index (PRI) in ILD was higher than that in HC (P = 0.014). Chest (46.1%) accounted for the highest of overall pain locations in subjects with ILD. Associated clinical factors for pain intensity in the patients with ILD included exposure history of risk factors of ILD, with a longer distance of 6MWD (≥ 250 m), and a higher mMRC score (2–4). The patients with ILD and pain are more likely to suffer impaired HRQoL (P = 0.0014) and psychological problems (P = 0.0017, P = 0.044). Conclusion The pain is common in those with ILD and the pain intensity is associated with exposure history, 6MWD, and mMRC score. The patients with ILD and pain were possibly to suffer depression, anxiety, and impaired HRQoL.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Valsaraj Payini ◽  
Kartikeya Bolar ◽  
Jyothi Mallya ◽  
Vasanth Kamath

Purpose This study aims to identify and validate the different clusters of wine festival visitors based on their hedonic motivation. Further, this study also sought how identified clusters were different in terms of perceived value, satisfaction and loyalty to the wine festival. Design/methodology/approach A survey was conducted during the International Beach Wine Festival held in Karnataka, India, to collect primary data from 400 visitors. Data were subjected to a two-step cluster analysis. Further, cluster segmentation based on visitors’ demographics, perceived value, satisfaction and loyalty was conducted. Decision tree analysis based on recursive partitioning algorithm was used to validate the clusters. Findings A two-step cluster analysis identified two distinct segments and named those as elite and informal visitors based on hedonic motivation. The cluster scores show that the elite group had the best ratings on social status, socialization and family harmony. On the other hand, the informal group had top scores for wine tasting, enjoyment, change from routine and the festival atmosphere. Decision tree analysis results indicate that social status enjoyment and taste motives differentiate an informal group from the elite group. Research limitations/implications This study was conducted in a wine festival held in a single location. To assess the strength of the results, case studies in other regions will be of importance. Originality/value This study extended the knowledge of the wine festival by adapting hedonic motivation as a basis for wine festival segmentation. Besides, this study’s empirical findings would greatly benefit wine festival organizers to formulate an appropriate marketing strategy to target each wine festival visitors’ cluster based on the differentiating factors obtained from the decision tree modelling.


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