scholarly journals Prevalence and Clinical Characteristics of Aquagenic Pruritus among Medical and Pharmacy Students in Lomé (Togo)

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Julienne Noude Teclessou ◽  
Koussake Kombate ◽  
Abla Sefako Akakpo ◽  
Abas Mouhari-Toure ◽  
Julie Zoua ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Medical Students ◽  
Sex Ratio ◽  
Clinical Characteristics ◽  
Descriptive Study ◽  
Personal History ◽  
Pharmacy Students ◽  
Common Condition ◽  
History Of ◽  
Lukewarm Water

Objective. The aim of this study was to determine the prevalence and clinical characteristics of aquagenic pruritus (AP) in medical students in Lomé (Togo). Methods. This was a prospective and descriptive study conducted among medical students in Lomé from June 1st to August 30th, 2019. The data collection questionnaire was anonymous composed of sociodemographic variables, bathing habits, and history of allergy responding to the concept of aquagenic pruritus and its characteristics. Results. In our study, 129/591 medical students had AP, giving a prevalence of AP to 21.8%. The average age of students with AP was 23.9 years, and the M/F sex ratio was 1.5. AP was not present after each bath in 100% of the medical students who suffered from it and lasted an average of 9.09 minutes. It was characteristically pruritic (60.5%) or tingling (38.0%) and localized (45.0%) or generalized (55.0%) in respondents with history of AP. There was a significant association between the presence of AP and a personal history of allergic rhinitis (p<0.01) and the presence of AP and a family AP (p<0.01). Twenty-six (20.2%) respondents with AP feared taking a bath. Bathing with warm or lukewarm water (29.5%) or applying menthol ointment (27.1%) were the main precautions taken to reduce AP. Conclusion. Aquagenic pruritus is a common condition in medical students in Togo. It occurs mainly in males and can be familial.

scholarly journals Epidemiological characteristics, clinical characteristics, and prognostic factors of children with atopy hospitalised with adenovirus pneumonia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Miao Li ◽  
Xiao-Hua Han ◽  
Li-Yun Liu ◽  
Hui-Sheng Yao ◽  
Li-Li Yi
Keyword(s):  
Risk Factors ◽  
Disease Severity ◽  
Clinical Characteristics ◽  
Severe Infection ◽  
Small Airway ◽  
Personal History ◽  
Factors Associated ◽  
History Of ◽  
Radiological Changes ◽  
Epidemiological Characteristics

Abstract Background Atopy may be associated with disease severity and a poor prognosis of human adenovirus (HAdV) pneumonia in children. Our aim was to observe the clinical characteristics and pulmonary radiological changes in children with atopy and HAdV pneumonia in China. Methods Children hospitalised with HAdV pneumonia from June 2018 to December 2019 were analysed. All children were divided into atopic with HAdV, non-atopic with HAdV, and atopic without HAdV infection group. Each group was further divided into the mild and severe pneumonia groups according to disease severity. Standard treatment was initiated after admission, and regular follow-up evaluations were conducted at 1 month after discharge. Baseline and clinical characteristics and pulmonary radiological changes in children with and without atopy were evaluated. Risk factors associated with small airway lesions in patients with HAdV pneumonia were analysed. Results The eosinophil count in the atopic group was significantly higher than that in the non-atopic group (P < 0.05). Severe coughing, wheezing, and small airway lesions on chest high-resolution computed tomography (HRCT) upon admission, after discharge and 1 month after discharge were significantly higher in the atopic group (with or without HAdV infection) than in the non-atopic group (P < 0.05). There were significant differences in the number of patients with wheezing and small airway lesions during hospitalisation and after discharge among the three groups (P < 0.05). The risks of small airway lesions in children with a family or personal history of asthma, severe infection, atopy, and HAdV infection were 2.1-, 2.7-, 1.9-, 2.1-, and 1.4-times higher than those in children without these characteristics, respectively. Conclusions Children with atopy and HAdV pneumonia may experience severe coughing in mild cases and wheezing in mild and severe cases. Children with atopy are more susceptible to the development of small airway lesions, recurrent wheezing after discharge and slower recovery of small airway lesions as observed on pulmonary imaging than non-atopic children after HAdV infection. A family or personal history of asthma, atopy, severe infection, and HAdV infection are independent risk factors associated with the development of small airway lesion as observed on chest HRCT.

Prevalence of BRCA2 mutations and other clinical characteristics in women with triple-negative breast cancer.

2014 ◽  
Vol 32 (26_suppl) ◽  
pp. 160-160
Author(s):  
Jennifer Chun ◽  
Freya Ruth Schnabel ◽  
Shira Schwartz ◽  
Jessica Billig ◽  
Karen Hiotis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
At Risk ◽  
Genetic Testing ◽  
Clinical Characteristics ◽  
Triple Negative ◽  
Ductal Carcinoma ◽  
Personal History ◽  
Breast Cancers ◽  
History Of ◽  
Brca2 Mutations

160 Background: Triple-negative breast cancers (TNBC) represent 10%–20% of invasive breast cancers. Current guidelines recommend genetic testing for women who are diagnosed with TNBC. Studies have shown that BRCA1 mutations are associated with TNBC, but there is little information on the relationship of BRCA2 mutations and TNBC. The purpose of this study was to look at the clinical characteristics of TNBC compared to non-TNBC in a cohort of women with newly diagnosed breast cancer. Methods: The Breast Cancer Database at our institution was queried for patients with invasive breast cancer. We included the following variables: age, race, BRCA1,2, tumor characteristics, and personal history of breast cancer (PHBC). Statistical analyses included Pearson’s Chi-Square and Fisher’s Exact Tests. Results: Out of a total of 1,332 women, 125 (9%) had TNBC. The median age for both TNBC and non-TNBC was 59 years. Majority of women had early stage breast cancer (92%) with ductal carcinoma (80%). There was a significantly higher proportion of Blacks and Asians with TNBC (p < 0.0001). Women with TNBC had higher Ki-67 (p < 0.0001). Within the TNBC group, there were 12 (29%) patients who tested positive for BRCA1,2 mutation and 23 (8%) who tested positive for BRCA 1,2 mutations in the non-TNBC group. Interestingly, BRCA1 was not associated with TNBC (p = 0.40) and BRCA2 was significantly associated with TNBC (p < 0.0001). We also found a higher proportion of TNBC in women who had a PHBC (p = 0.01). Conclusions: In our study, women with TNBC were similar in age to women who did not have TNBC. We found that the women with TNBC in our cohort had elevated rates of BRCA2 mutations. We also found that women with a personal history of breast cancer were at risk for developing TNBC. This may be related to the use of hormonal therapy that reduces the risk of ER/PR-positive tumors. Women of all ages are at risk for developing TNBC and older age at TNBC should not deter from genetic testing.

scholarly journals Gambaran nyeri kepala primer pada mahasiswa angkatan 2013 Fakultas Kedokteran Universitas Sam Ratulangi Manado

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Yafet Tandaju ◽  
Theresia . Runtuwene ◽  
Mieke A.H.N. Kembuan
Keyword(s):  
Medical Students ◽  
Family History ◽  
Cluster Headache ◽  
Migraine With Aura ◽  
Migraine Without Aura ◽  
Primary Headache ◽  
Descriptive Study ◽  
Headache Type ◽  
History Of ◽  
Pain Questionnaires

Abstract: This study aimed to obtain the profile of primary headache among medical students batch 2013 in University of Sam Ratulangi Manado. This was a descriptive study. The headache description was assessed with questionnaires (Pain questionnaires PERDOSSI). There were 176 respondents consisted of 45 males and 131 females. The percentages of each headache type were as follows: tension-type 64%, migraine without aura 20%, migraine with aura 15%, and cluster headache 1%. The results showed that stress triggered 84% of headache cases. There were 73% of respondents who suffered from headache had family history of headache.Keywords: primary headache, types of headache Abstrak: Penelitian ini bertujuan untuk mendapatkan gambaran nyeri kepala primer pada mahasiswa kedokteran Universitas Negeri Sam Ratulangi angkatan 2013. Jenis penelitian ini deskriptif. Deskripsi nyeri kepala pada responden dinilai dengan kuesioner (kuesioner nyeri PERDOSSI ). Terdapat 176 responden, terdiri dari 45 responden laki-laki dan 131 responden perempuan. Persentase untuk setiap jenis sakit kepala ialah sebagai berikut: tipe tegang 64%, migraine tanpa aura 20%, migrain dengan aura 15%, dan nyeri kepala klaster 1%. Hasil penelitian menunjukkan bahwa stres memicu 84% dari kasus nyeri kepala. Pada penelitian ini didapatkan 73% dari responden yang menderita serangan nyeri kepala memiliki riwayat keluarga sakit kepala.Kata kunci: nyeri kepala primer, jenis sakit kepala

scholarly journals Epidemiology, Clinical Characteristics, and Prognostic Factors of Atopic Children Hospitalised for Adenovirus Infection: A Single Institutional Study in Shenyang, China

2020 ◽  
Author(s):  
Miao Li ◽  
Xiao-Hua Han ◽  
Li-Yun Liu ◽  
Hui-Sheng Yao ◽  
Li-Li Yi
Keyword(s):  
Clinical Characteristics ◽  
Severe Infection ◽  
Airway Disease ◽  
Small Airway ◽  
Personal History ◽  
Factors Associated ◽  
Small Airway Disease ◽  
Number Of Patients ◽  
History Of ◽  
Radiological Changes

Abstract Background: Atopy may be associated with the severity of disease and poor prognosis after adenovirus (Adv) infection in children. Our aim was to observe the clinical characteristics and pulmonary radiological changes in atopic children with Adv pneumonia in China.Methods: Children hospitalised for Adv pneumonia from June 2018 to Dec 2019 were analysed. All children were divided into three groups: atopic with Adv, non-atopic with Adv, and atopic without Adv infection. Each group was further divided into mild or severe infection groups according to disease severity. Standard treatment was initiated after admission and regular follow-up evaluations were conducted at 1 month after discharge. Baseline and clinical characteristics, and pulmonary radiological changes of atopic and non-atopic children were collected. Risk factors associated with small airway diseases in Adv pneumonia patients were analyzed.Results: Compared with non-atopic children with Adv infection, the cases of eosinophilic granulocyte count were significantly higher in atopic children than non-atopic children (P<0.05). Among children with mild and severe infection, the number of patients with wheezing and small airway disease as observed by high-resolution computed tomography (HRCT) was significantly higher in atopic children than non-atopic children (P<0.05). Furthermore, coughing was more severe in atopic children than non-atopic children (P<0.05). A family history of asthma (OR 2.1 [95% CI 1.8–3.0]), personal history of asthma (OR 2.7 [95% CI 2.1–3.1]), atopy (OR 2.1 [95% CI 1.8–3.2]), severe infection (OR 1.9 [95% CI 1.0–2.7]), and Adv infection (OR 1.4, [95% CI 0.9–2.0]) were independent factors associated with the development of small airway disease, both after admission and a month after discharge. Conclusions: Atopic children with Adv infection experience more severe coughing during hospitalisation and are prone to wheezing and small airway disease on the HRCT. Family and personal history of asthma, atopy, severe infection, and Adv infection were independent factors associated with the development of small airway disease on the chest HRCT scan.

scholarly journals Epidemiology , clinical characteristics, and prognostic factors of atopic children hospitalised for adenovirus infection

2020 ◽  
Author(s):  
Miao Li ◽  
xiao-hua Han ◽  
li-yun Liu ◽  
hui-sheng Yao ◽  
li-li Yi
Keyword(s):  
Clinical Characteristics ◽  
Severe Infection ◽  
Airway Disease ◽  
Small Airway ◽  
Personal History ◽  
Factors Associated ◽  
Small Airway Disease ◽  
Number Of Patients ◽  
History Of ◽  
Radiological Changes

Abstract Background Atopy may be associated with the severity of disease and poor prognosis after adenovirus (Adv) infection in children. Our aim was to observe the clinical characteristics and pulmonary radiological changes in atopic children with Adv pneumonia in China. Methods Children hospitalised for Adv pneumonia from June 2018 to Dec 2019 were analysed. All children were divided into three groups: atopic with Adv, non-atopic with Adv, and atopic without Adv infection. Each group was further divided into mild or severe infection groups according to disease severity. Standard treatment was initiated after admission and regular follow-up evaluations were conducted at 1 month after discharge. Baseline and clinical characteristics, and pulmonary radiological changes of atopic and non-atopic children were collected. Risk factors associated with small airway diseases in Adv pneumonia patients were analyzed. Results Compared with non-atopic children with Adv infection, the cases of eosinophilic granulocyte count were significantly higher in atopic children than non-atopic children (P < 0.05). Among children with mild and severe infection, the number of patients with wheezing and small airway disease as observed by high-resolution computed tomography (HRCT) was significantly higher in atopic children than non-atopic children (P < 0.05). Furthermore, coughing was more severe in atopic children than non-atopic children (P < 0.05). A family history of asthma (OR 2.1 [95% CI 1.8–3.0]), personal history of asthma (OR 2.7 [95% CI 2.1–3.1]), atopy (OR 2.1 [95% CI 1.8–3.2]), severe infection (OR 1.9 [95% CI 1.0–2.7]), and Adv infection (OR 1.4, [95% CI 0.9–2.0]) were independent factors associated with the development of small airway disease, both after admission and a month after discharge. Conclusions Atopic children with Adv infection experience more severe coughing during hospitalisation and are prone to wheezing and small airway disease on the HRCT. Family and personal history of asthma, atopy, severe infection, and Adv infection were independent factors associated with the development of small airway disease on the chest HRCT scan.

scholarly journals NORMAL CORONARY ANGIOGRAM;

2017 ◽  
Vol 24 (09) ◽  
pp. 1271-1274
Author(s):  
Naeem Asghar ◽  
M. Faiq Ilyas ◽  
Muhammad Nazim
Keyword(s):  
Family History ◽  
Clinical Characteristics ◽  
Stress Test ◽  
Descriptive Study ◽  
Coronary Angiogram ◽  
Normal Coronary Angiogram ◽  
History Of ◽  
Artery Disease ◽  
Post Menopausal ◽  
Coronary Arterydisease

Objectives: To observe the clinical characteristics of patients having normalcoronary angiogram following an abnormal stress test or presented with chest pain indicatingcoronary angiogram. Study Design: A single center retrospective, descriptive study. Period:Coronary angiograms done from September 2015 to September 2016 were retrievedand reviewed for normal coronary arteries. Setting: Khatum-un-Nabyeen Heart Center.Methodology: Clinical profile of the patients having normal coronary angiogram was retrievedfrom hospital record. Results: Out of 900 angiograms reviewed, 81(9%) were having normalcoronary arteries. Mean age was 43±10 years. Females were 64.1%. Clinical characteristicof study group was as follows: smokers 32.09%, family history of premature coronary arterydisease 51.8%, hyperlipidemia 60.4% and hypertension 19.7%. Diabetes was present onlyin 20.9%. Among females: 19.2% were current users of oral contraceptives pills and 13.4%were post menopausal. Mean BMI was 25.4±4. Conclusion: Normal coronary angiogram isinfrequent observation in cardiac catheterization laboratories and mostly found in youngerto middle aged females. Family history of coronary artery disease and hyperlideimaare verycommon in such patients.

Prevalence and Clinical Characteristics of Headache in Medical Students of the University of Lagos, Nigeria

Cephalalgia ◽  
2009 ◽  
Vol 29 (4) ◽  
pp. 472-477 ◽  
Author(s):  
FI Ojini ◽  
Nu Okubadejo ◽  
MA Danesi
Keyword(s):  
Medical Students ◽  
Prescription Drugs ◽  
Clinical Characteristics ◽  
Tension Type Headache ◽  
Primary Headaches ◽  
Medical Assistance ◽  
Consultation Rate ◽  
History Of ◽  
Type Headache ◽  
The University

We investigated the 1-year prevalence, clinical features and mode of treatment of headache in medical students of the University of Lagos, Nigeria, using a self-administered headache questionnaire. Headache prevalence was 46.0% and was significantly higher in women than in men (62.8% vs. 34.1%). Prevalence of tension-type headache was higher than that of migraine (18.1% vs. 6.4%). Although tension-type headache had a similar prevalence in both sexes (male 17.3%, female 19.2%), migraine was three times more common in women (10.9% vs. 3.2%). A family history of headache was present in 22.0%. Only 4.6% sought medical assistance, whereas 68.2% took non-prescription drugs, mainly simple analgesics. Specific drugs for migraine and tension-type headache were rarely used. In conclusion, 1-year headache prevalence is high among medical students at this university. The low consultation rate and the rarity of usage of specific anti-headache drugs probably reflect inadequacies in the management of primary headaches in this population.

Recurrent wheezing, allergic rhinitis, and maternal asthma as predictors of asthma in children

2020 ◽  
Vol 41 (3) ◽  
pp. 204-209
Author(s):  
Ilson Meireles-Neto ◽  
Alexandre M. Pimentel ◽  
Juliana N. Parreira ◽  
Maria-Socorro H. Fontoura ◽  
Cristiana M. Nascimento-Carvalho
Keyword(s):  
Allergic Rhinitis ◽  
Medical Records ◽  
Case Control Study ◽  
Personal History ◽  
School Age Children ◽  
Recurrent Wheezing ◽  
Maternal History ◽  
History Of ◽  
Asthma In Children ◽  
Control Study

Background: Early prediction of asthma is crucial for asthma prevention. Objective: We estimated the odds ratio (OR) of recurrent wheezing during the first 3 years of life, atopic rhinitis, and maternal asthma for asthma in school-age children (ages ≥ 6 years). Methods: This case-control study was conducted in Salvador, Brazil. Medical records of children diagnosed with asthma (cases) and of children screened for pulmonary illnesses and without asthma (controls) were reviewed. Information was retrieved and registered in standardized forms. Results: We included 125 subjects (cases) and 375 controls, whose median (percentile 25th‐percentile 75th) age was 8.1 years (6.6‐10.0 years) and 9.2 years (7.0‐11.9 years), respectively. The subjects (cases) and the controls had at least three episodes of wheezing during the first 3 years of life (69.7% and 1.4%, respectively), a maternal history of asthma (36.0% and 4.0%, respectively), and atopic rhinitis (95.9% and 35.1%, respectively). The adjusted OR of three or more episodes of wheezing during the first 3 years of life was OR 132.5 (95% confidence interval [CI], 36.8‐477.1), of a personal history of atopic rhinitis was OR 21.3 (95% CI, 5.3‐85.0), and of maternal asthma was OR 10.2 (95% CI, 3.1‐33.6) for asthma in a logistic regression (which also included age, gender, and maternal history of allergic rhinitis [OR insignificant for these factors]). Conclusion: Children with a history of three or more episodes of wheezing during the first 3 years of life were at least 37 times more likely to develop asthma than children without this history. A maternal history of asthma and a personal history of atopic rhinitis are also predictors of asthma in children.

scholarly journals Prevalence Refractive Errors among Medical Students of Qassim University, Saudi Arabia: Cross-Sectional Descriptive Study

2018 ◽  
Vol 6 (5) ◽  
pp. 940-943 ◽  
Author(s):  
Sultan H. Al-Rashidi ◽  
Adel A. Albahouth ◽  
Waleed A. Althwini ◽  
Abdullah A. Alsohibani ◽  
Abdulmejeed A. Alnughaymishi ◽  
...  
Keyword(s):  
Social Sciences ◽  
Medical Students ◽  
Total Sample ◽  
Descriptive Study ◽  
Ocular Surgery ◽  
Cross Sectional ◽  
Common Error ◽  
Academic Class ◽  
History Of ◽  
Study Population

OBJECTIVE: To study the prevalence of various errors of refraction among the medical students studying at the college of medicine, Qassim University, Saudi Arabia.METHODS: This is a cross-sectional descriptive study conducted at Qassim University clinics over a period of two months. The study population comprised 162 male and female students from different academic years. The students were selected randomly so that around 35-40 students were taken from each academic class. The selected study population was explained the objectives of the study and a written consent form that stated the purpose, methods, risks, benefits, and the assurance of the confidentiality of the data was obtained from each student. After giving the consent, each subject was examined by auto refractometer. The examination was carried out by an optometrist without using cycloplegia. Both right and left eyes were thoroughly examined by auto refractometer and on the average three readings of the refraction measurements were taken. The readings were recorded on a data sheet of every individual, and the Statistical analysis was performed using Statistical Package for Social Sciences (SPSS).RESULTS: One hundred and sixty-two (162) students with a mean age of 22.44 years, Std 1.661 and a range of 8 (19-27) were included in the study. Of the total number, 111 (68.51%) were males and remaining 51 (31.48%) were females. Of the total sample, only 1 (0.617%) student had diabetes mellitus, and 6 (3.70%) students gave a history of previous ocular surgery. Myopia was found to be the commonest error of refraction 53.7% with hyperopia next to it.CONCLUSION: Myopia is found to be a common error of refraction in young adults. A regular checkup is essential to timely correct the error and to prevent deterioration of the vision.

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

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