scholarly journals Impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology Classification of Thyroid Nodules in the Treatment of Indeterminate Follicular Lesions: Five-Year Results at a Single Center

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
M. Pastoricchio ◽  
A. Cubisino ◽  
A. Lanzaro ◽  
M. Troian ◽  
F. Zanconati ◽  
...  

Purpose. Aim of the study was to assess the impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology (SIAPEC) classification of 2014, on the treatment of indeterminate thyroid lesions (TIR3). Methods. We retrospectively analyzed patients undergoing thyroid surgery for TIR3 lesions between 2013 and 2018, at the General Surgery Department of Trieste University Hospital. According to the SIAPEC classification, patients were divided into TIR3A and TIR3B groups. All patients treated before 2014 underwent surgical treatment, and surgical specimens were retrospectively classified after revision of fine-needle aspiration cytology. Starting 2014, TIR3A patients were treated only when symptomatic (i.e., coexistent bilateral thyroid goiter or growing TIR3A nodules), whereas TIR3B patients always received surgical treatment. Hemithyroidectomy (HT) was the procedure of choice. Total thyroidectomy (TT) was performed in case of concurrent bilateral goiter, autoimmune thyroid disease, and/or presence of BRAF and/or RAS mutation. Lastly, we analyzed the malignancy rate in the two groups. Results. 29 TIR3A and 90 TIR3B patients were included in the study. HT was performed in 10 TIR3A patients and 37 TIR3B patients, respectively, with need for reoperation in 4 TIR3B (10.8%) patients due to histological findings of follicular thyroid carcinoma >1  cm. The malignancy rates were 17.2% in TIR3A and 31.1% in TIR3B, (p=0.16). Predictability of malignancy was almost 89% in BRAF mutation and just 47% in RAS mutation. Conclusions. The new SIAPEC classification in association with biomolecular markers has improved diagnostic accuracy, patient selection, and clinical management of TIR3 lesions.

2017 ◽  
Vol 71 (2) ◽  
pp. 16-21 ◽  
Author(s):  
Gabriela Czerwińska ◽  
Wojciech Ścierski ◽  
Grzegorz Namysłowski ◽  
Grażyna Lisowska ◽  
Maciej Misiołek

Background: Otosclerosis is a cause of 5–9% of all hearing loss. The most effective treatment of otoslerosis is stapedotomy. Aim: The aim of this study was to evaluate the results of otosclerosis surgical treatment and to examine the impact of disease stage, time of the signs, age and sex on the results. Material and methods: 105 patients who underwent operation due to otosclerosis at the Department of Otolaryngology University Hospital in Zabrze at the age of 18–65 were analyzed. In 25 patients stapedotomy was bilateral. 130 cases of treated ears were included in the statistical analysis. The state of hearing after operation was evaluated with regard to guidance of Hearing and Balance Committee of American Academy of Otolaryngology – Head and Neck Surgery and with consideration of suggestions made by European Academy of Otolaryngology and Neurootology. Mean values of bone and air conduction, air bone gap before, one year after treatment, and at least 4 years after surgery were compared. The influence of stage of the disease in terms of Shambaugh index, lasting of signs, age and sex were evaluated with regard to change of mean hearing loss according to Bell Telephone Laboratories. Results: On the basis of hearing examination evaluating improvement in air and bone conduction and reduction of cochlear reserve, very good and good treatment results were obtained in over 90% of patients in short and long term observations. No influence of disease stage, time of signs lasting, age and sex on the results of treatment – with regard to change in mean hearing loss was shown.


2018 ◽  
Vol 159 (2) ◽  
pp. 386-393 ◽  
Author(s):  
Ignacio Javier Fernandez ◽  
Francesco Maria Crocetta ◽  
Marco Demattè ◽  
Paolo Farneti ◽  
Marta Stanzani ◽  
...  

Objective The aims of the present study were to evaluate the clinical significance of the delay for surgical treatment and the prognostic value of other clinical, pathologic, and microbiological variables among hematologic patients affected by acute invasive fungal rhinosinusitis (AIFRS). Furthermore, we propose our early diagnosis and treatment protocol, reporting its 10-year results. Study Design Monocentric retrospective analysis. Setting The study was conducted from 2001 to 2017 at the University Hospital of Bologna, Italy. Subjects and Methods The impact of time to treatment and clinical, pathologic, and microbiological variables were analyzed among patients with histologically and microbiologically proven AIFRS. The outcomes of patients treated before the introduction of the early diagnosis protocol were compared with those treated afterward. Results Nineteen patients affected by AIFRS were eligible for the study. Treatment delay >4 days ( P = .002), infection caused by Mucorales ( P = .015), and extension of the disease were negative prognostic variables ( P = .017). The application of our protocol significantly reduced the delay for diagnosis and appropriate treatment by an average of 7.3 days ( P = .02). Conclusion The promptness of the diagnosis and surgical treatment may play a significant role in the management of AIFRS, as it appears to be significantly associated with the disease outcome. Our protocol may help to reduce the time required for diagnosis of high-risk hematologic patients.


2012 ◽  
Vol 27 (5) ◽  
pp. 311-314 ◽  
Author(s):  
Débora Eleotério de Lima ◽  
Joel Veiga Filho ◽  
Leda Marques Ribeiro ◽  
Thiago Bezerra de Morais ◽  
Luiz Roberto Martins Rocha ◽  
...  

PURPOSE: To analyze the direct costs of conservative surgical treatment of breast cancer, performed in a university hospital, to the Brazilian National Health Care Public System (SUS), checking the impact of the oncoplastic approach on these costs. METHODS: One hundred thirty eight breast cancer patients who had undergone conservative treatment with oncoplastic approach (n=36) or not (control group, n=102), in the period from 2005 to 2010, were enrolled. Sociodemographic and clinical data were recorded. The direct costs of the surgical procedure were obtained and analyzed. RESULTS: Groups did not differ in regard to age (p=0.963), and patients in oncoplastic group had a longer time of hospital stay (p=0.000). The median direct cost for the oncoplastic group was R$461.00 and for the control group was R$229.00 (p=0.000). CONCLUSION: The oncoplastic approach has generated higher direct costs in conservative surgical treatment of breast cancer to SUS.


2021 ◽  
Vol 8 ◽  
Author(s):  
Younes Aggouri ◽  
Aymane Jbilou ◽  
Badr Tarif ◽  
Yassine Mohamed ◽  
Youssef Motiaa ◽  
...  

On March 11, 2020, the WHO declared that the epidemic of COVID-19 had become a pandemic, and this disrupted all the regulated operative programs. On the other hand and by its urgent nature, the emergency surgery was maintained with particularity in some situations, an association with infection by COVID-19. The circumstances of diagnosis of the association of infection by COVID-19 and surgical emergency are based on clinical, radiological, and biological criteria. In this work we report the experience of the University Hospital of Tangier concerning the management of three patients with the particularity of associating a covid infection and a digestive surgical emergency, we will discuss through these cases, the necessary protective measures in intraoperative and the impact of the covid infection on the morbi-mortality Concerning the impact of covid infection on postoperative morbidity and mortality, there are generally two situations: When the covid infection is benign, the prognosis depends on the severity of the surgical emergency and in this situation the prognosis is the same as for patients not infected by covid, this is the case of the first and third cases. The second situation; when the covid infection is severe, it has a great impact on the prognosis and the postoperative care in intensive care. With this publication, we are trying to provide information to help surgeons better manage this category of patients, especially in view of the panic caused by the pandemic, and the difficulty of adapting to the new patient circuit, but more studies recruiting more cases are needed to confirm our findings.


Author(s):  
Monka Marius ◽  
Ohoya Etsaka Terence Olivier ◽  
Massouama Regis ◽  
Ngatsé-Oko Albert ◽  
Moyikoua Armand

<p class="abstract"><strong>Background:</strong> The objective of the study was to evaluate the functional and anatomical results of the surgical treatment of fractures of the distal humerus at Brazzaville University Hospital using non-anatomical plates.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective study of patients operated by screwed plates for fracture of the distal humerus at Brazzaville University Hospital between January 2014 and December 2017. The study included 11 patients operated by non-anatomical plates and responding the inclusion criteria. Fractures of the distal humerus were distributed according to the AO classification of Müller and Nazarian. The functional results were evaluated according to the Mayo Clinic score based on 4 criteria: pain, mobility bow, stability and functional capacity.<strong></strong></p><p class="abstract"><strong>Results:</strong> There were 8 men and 3 women. The average age was 35 years (range 23 to 50 years). Causes of the trauma were a road accident in 7 patients and a fall in 4 patients. The site involved in the trauma was lateral right in 7 patients and left in 4 patients. The average time to surgery was 7 days (range 5 to 12 days). All our patients have consolidated in first intention. The average time to consolidation was 3 months (range 3 to 4 months). Results at the average follow-up of 9 months were considered excellent in 3 patients, good in 6 patients and average in 2 patients.</p><p class="abstract"><strong>Conclusions:</strong> Osteosynthesis of fractures of the distal humerus remains a challenge in developing countries. Our experience shows that surgical treatment of fractures of the distal humerus by non-anatomic plates can give good results when bone stabilization is satisfactory and rehabilitation is undertaken early.</p>


2020 ◽  
Vol 9 (3) ◽  
pp. 97-102
Author(s):  
Robert Ślusarz ◽  
◽  
Karolina Filipska ◽  
Beata Haor ◽  
Agnieszka Królikowska ◽  
...  

Introduction. Discopathic lesions of the lumbosacral spine are the most frequently recorded diseases of the osteoarticular and peripheral nervous system. Aim. The main aim of the study was to evaluate the influence of selected demographic and clinical factors on the social and economic situation of patients after surgical treatment of the lumbosacral discopathy. Material and Methods. The research was carried out at the Department of Neurosurgery, University Hospital in Bydgoszcz on a group of 137 patients diagnosed with lumbosacral discopathy. The study consisted of double assessment of the patient’s condition, taking into account the social and economic situation of the respondents. The Prolo Scale was used for this purpose. Results. It was found that both the social and economic situation of the respondents after the surgery was definitely better than before the surgery (p < 0.001). Final results were independent of gender, age and location of the lesion (p > 0.05). A statistically significant dependence of the final results on the type of work performed, the intensity of pain and the patient’s body weight was demonstrated (p < 0.05). Conclusions. The social and economic situation of patients with diagnosed lumbosacral discopathy improves significantly after surgery. There was a relationship between the type of work performed and the social and economic situation of the respondents. Among the clinical factors, the degree of pain intensity and the patient’s body weight significantly influenced the social and economic situation of the respondents. (JNNN 2020;9(3):97–102) Key Words: clinical factors, demographic factors, lumbosacral discopathy, socioeconomic situation


2019 ◽  
pp. 27-35
Author(s):  
Alexandr Neznamov

Digital technologies are no longer the future but are the present of civil proceedings. That is why any research in this direction seems to be relevant. At the same time, some of the fundamental problems remain unattended by the scientific community. One of these problems is the problem of classification of digital technologies in civil proceedings. On the basis of instrumental and genetic approaches to the understanding of digital technologies, it is concluded that their most significant feature is the ability to mediate the interaction of participants in legal proceedings with information; their differentiating feature is the function performed by a particular technology in the interaction with information. On this basis, it is proposed to distinguish the following groups of digital technologies in civil proceedings: a) technologies of recording, storing and displaying (reproducing) information, b) technologies of transferring information, c) technologies of processing information. A brief description is given to each of the groups. Presented classification could serve as a basis for a more systematic discussion of the impact of digital technologies on the essence of civil proceedings. Particularly, it is pointed out that issues of recording, storing, reproducing and transferring information are traditionally more «technological» for civil process, while issues of information processing are more conceptual.


2012 ◽  
pp. 58-65
Author(s):  
Duy Thai Truong ◽  
Van Dung Phan ◽  
Tu The Nguyen

Objective: Study on clinical characteristics and result of treatment benign vocal cord tumor with suspensive laryngeal endoscopic surgery. Materials and Methods: A prospective study was undertaken in 43 patients who had benign vocal cord tumor and performed a suspensive laryngeal endoscopic surgery at ENT Dept. of Hue University Hospital, from 3/2010 to 5/2011. Results: The most common was group was 31 - 45 (44.2%). There was no difference of gender. Moderate hoarness was 67.4%. Classification of benign laryngeal tumor: vocal nodules (13 cases), vocal cyst (18 cases), vocal polyp (10 cases) and Reinke’s edema (2 cases). The successful treatment rate of vocal benign tumor was 88.4%. Conclusions: Suspensive laryngeal endoscopic surgery was the best method to cure benign vocal cord tumor. The surgeon had a clear operative field, easy manoeuver, high rate of cure and less complication.


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