scholarly journals Novel Approaches for Diagnosing and Management of Cardiovascular Disorders Mediated by Oxidative Stress

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Adrian Doroszko ◽  
Aneta Radziwon-Balicka ◽  
Robert Skomro
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disorders ◽  
Novel Approaches

Aging, Oxidative Stress, and Cardiovascular Disorders

2010 ◽  
pp. 259-275
Author(s):  
Yi Shi ◽  
Giovanni G. Camici ◽  
Thomas F. Lüscher
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disorders

Role of Polyherbal Formulations of Medicinal Plants From Himalayan Regions in the Management of Diabetes

2022 ◽  
pp. 212-229
Author(s):  
Ashfaq Ahmad Shah ◽  
Sumaira Qayoom ◽  
Amit Gupta ◽  
Aqueel Ur Rehman
Keyword(s):  
Quality Of Life ◽  
Oxidative Stress ◽  
Metabolic Diseases ◽  
Polyphenolic Compounds ◽  
Health Concern ◽  
Glucose Measurement ◽  
Diabetes Research ◽  
Cardiovascular Disorders

Current research on phytochemicals is mainly focused on novel phenolic and polyphenolic compounds expressing their potential as therapeutic agents in various diseases like cancer, autoimmune diseases, cardiovascular disorders, diabetes, oxidative stress-related diseases, as well as their properties to inhibit the growth and proliferation of infectious agents. Among the human physiological disorders, one of the most severe endocrine metabolic diseases is Diabetes mellitus which is a clinical disease distinguished by a deficit in the production of insulin or resistance to the action of insulin. Globally, diabetes is an increasing health concern which is now emerging as an epidemic. About 700-800 plants are exhibiting anti-diabetic activity that has been studied. As far as nanotechnology in diabetes research is concerned, it has made possible the buildout of novel glucose measurement as well as insulin delivery modalities that possess the potential to excellently enhance the quality of life of the diabetic patient.

scholarly journals Biomarkers of oxidative and nitro-oxidative stress: conventional and novel approaches

2017 ◽  
Vol 174 (12) ◽  
pp. 1771-1783 ◽  
Author(s):  
Ana Cipak Gasparovic ◽  
Neven Zarkovic ◽  
Kamelija Zarkovic ◽  
Khrystyna Semen ◽  
Danylo Kaminskyy ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Novel Approaches

scholarly journals Recent novel approaches to limit oxidative stress and inflammation in diabetic complications

2018 ◽  
Vol 7 (4) ◽  
pp. e1016 ◽  
Author(s):  
Raelene J Pickering ◽  
Carlos J Rosado ◽  
Arpeeta Sharma ◽  
Shareefa Buksh ◽  
Mitchel Tate ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications ◽  
Novel Approaches

scholarly journals Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Fidèle Ntchapda ◽  
Christian Bonabe ◽  
Albert Donatien Atsamo ◽  
David Romain Kemeta Azambou ◽  
Yannick Bekono Fouda ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Aqueous Extract ◽  
Stem Bark ◽  
Cardiovascular Disorders ◽  
Oxidative Stress Markers ◽  
Adansonia Digitata ◽  
Stress Markers ◽  
Arterial Blood

Background. Adansonia digitata is a plant used against cardiovascular disorders in African folk medicine. We assessed the effects of the aqueous extract of its stem bark on the development of hypertension in L-NAME-induced hypertensive rats. Methods. The animals were administered L-NAME once daily for 3 weeks (25 mg/kg, i.p.), concomitantly with aqueous extract of A. digitata stem bark (100 and 200 mg/kg, p.o.) or captopril (20 mg/kg, p.o.). Then, hemodynamic and electrocardiographic parameters, oxidative stress markers, and the lipid profile were assessed in the blood and heart, aorta, and kidney homogenates, and histopathological analyses were performed. Results. L-NAME-induced hypertensive control animals, but not the animals concomitantly treated with A. digitata extract, displayed increases in the mean arterial blood pressure (21.64% difference, p<0.001, vs. dose 200 mg/kg), systolic arterial blood pressure (21.33%, p<0.001), and the diastolic arterial blood pressure (21.84%, p<0.001). In addition, hypertensive control animals displayed (i) increases in serum triglycerides, total cholesterol, LDL, and creatinine levels, malondialdehyde and transaminase activities, and atherogenic index; (ii) decreases in serum HDL, catalase, reduced glutathione, and nitric oxide; and (iii) aorta wall thickening, inflammatory cell infiltration, and cell loss in the cardiac muscle and renal tissues. As captopril, the extract prevented hypertension-like changes in lipid profile, cardiac, hepatic, and renal affection indicators, and oxidative stress markers. Conclusion. Our findings suggest that the extract of A. digitata has antihypertensive and antioxidant effects in L-NAME-induced hypertension rat models. These effects partly justify the traditional medicine use against cardiovascular disorders.

scholarly journals Novel Approaches in Diagnosing the Role of Inflammation in the Onset Cardiovascular Disorders

2018 ◽  
Vol 2018 ◽  
pp. 1-2
Author(s):  
Adrian Doroszko ◽  
Piotr Dobrowolski ◽  
Aneta Radziwon-Balicka ◽  
Robert Skomro
Keyword(s):  
Cardiovascular Disorders ◽  
Novel Approaches

scholarly journals Culinary–medicinal mushrooms: a review of organic compounds and bioelements with antioxidant activity

2020 ◽  
Author(s):  
Adrian Podkowa ◽  
Agata Kryczyk-Poprawa ◽  
Włodzimierz Opoka ◽  
Bożena Muszyńska
Keyword(s):  
Oxidative Stress ◽  
Central Nervous System ◽  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Cardiovascular Disorders ◽  
Indole Derivatives ◽  
Medicinal Mushrooms ◽  
Digestive Juice ◽  
The Central Nervous System ◽  
Artificial Digestive Juice

AbstractThere are about 3000 species of mushrooms, which have a high amount of substances that are beneficial to human health, such as antioxidants. It is well known that oxidative stress plays an important role in the etiopathogenesis of many diseases, including cancer, cardiovascular disorders, and diseases of the central nervous system. One way to prevent homeostasis disorders that occur as a result of excessive production of pro-oxidative substances is to include the ingredients having antioxidant properties in the diet. Several compounds, such as those with phenolic and indole derivatives as well as carotenoids and some vitamins, exhibit antioxidant activity. These substances are present in many foods, including mushrooms. In addition, they have certain unique compounds that are not found in other sources (e.g., norbadione A). The present work discusses selected ingredients exhibiting antioxidant activity, which are found in various species of mushrooms as wells as describes the content of these compounds in the extracts obtained from mushrooms using artificial digestive juice.

Sign in / Sign up

Export Citation Format

Share Document