scholarly journals Towards Analysis and Optimization of Electrospun PVP (Polyvinylpyrrolidone) Nanofibers

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Utkarsh ◽  
Hussien Hegab ◽  
Muhammad Tariq ◽  
Nabeel Ahmed Syed ◽  
Ghaus Rizvi ◽  
...  
Keyword(s):  
Sound Absorption ◽  
Fiber Diameter ◽  
Polymer Concentration ◽  
Electrospinning Process ◽  
Average Model ◽  
Model Accuracy ◽  
Electrospinning Technique ◽  
Array Design ◽  
Polymeric Nanofibers ◽  
Experimental Trials

In this study, the polymeric nanofibers of polyvinylpyrrolidone (PVP) were manufactured using the electrospinning technique. The electrospinning process parameters such as voltage, polymer concentration, rotational speed of the collecting drum, collecting distance, and flow rate were optimized to obtain the minimum fiber diameter for sound absorption applications. The effects of these parameters on the fiber diameter as output responses were investigated by analysis of variance (ANOVA) and Taguchi’s array design. Furthermore, a mathematical model was generated using response surface methodology (RSM) to model the electrospinning process. The high voltage and polymer concentration were observed to be the most significant parameters at 95% and 99% confidence level. The average model accuracy of 83.4% was observed for the predictive model of electrospinning which is considered acceptable as it is composed of complete experimental trials of 27 out of 243 runs. The experimental study offers a promising attempt in the open literature to carefully understand the effect of various electrospinning parameters when producing PVP nanofibers.

Optimizing Process Variables to Control Fiber Diameter of Electrospun Polycaprolactone Nanofiber Using Factorial Design

2011 ◽  
Vol 1316 ◽  
Author(s):  
Saida P. Khan ◽  
Kadambari Bhasin ◽  
Golam M. Newaz
Keyword(s):  
Dielectric Constant ◽  
Factorial Design ◽  
Fiber Diameter ◽  
Polymer Concentration ◽  
Engineering Application ◽  
Electrospinning Process ◽  
Solution Flow Rate ◽  
Tissue Engineering Application ◽  
Electrospinning Technique ◽  
Solution Flow

ABSTRACTIn the electrospinning process, fibers ranging from 50 nm to 1000 nm or greater can be produced by applying an electric potential to a polymeric solution [1, 2]. Our group has studied the fabrication of electro-spun Poly-caprolactone (PCL) nanofiber consisting of a range of fiber diameter (nm-um) and pore sizes. PCL is a biocompatible, FDA approved and biodegradable [3, 4] polymer. As a solvent we have used 2,2,2-trifluoroethanol (TFE) for its biocompatibility, conductivity and high dielectric constant. The electrospinning technique consists of a simple setup with a number of variables working in a complex and unpredictable way. The variables affecting fiber diameter are polymer concentration in the solution, flow rate, applied voltage, tip to collector distance, diameter of the needle/capillary, polymer/solvent dielectric constant etc. In our study we have found that concentration of the solution and molecular weight of the polymer are the most important parameters for forming the nanofibers and viscosity is important for the fiber diameter. To optimize so many variables to control the fiber diameter, we have used the factorial design method. The study is important for the fabrication of biomimetic scaffold for vascular implant and tissue engineering application.

scholarly journals Electrospun Nylon-6 Nanofibers and Their Characteristics

2020 ◽  
Vol 9 (1) ◽  
pp. 9-19
Author(s):  
Ida Sriyanti ◽  
Meily P Agustini ◽  
Jaidan Jauhari ◽  
Sukemi Sukemi ◽  
Zainuddin Nawawi
Keyword(s):  
Fiber Diameter ◽  
Peak Shift ◽  
Nylon 6 ◽  
Electrospinning Process ◽  
Electrospinning Technique ◽  
Fiber Concentration ◽  
Air Filters ◽  
Xrd Pattern ◽  
Electrospinning Method ◽  
Small Wave

The purposes of this research were to investigate the synthesized Nylon-6 nanofibers using electrospinning technique and their characteristics. The method used in this study was an experimental method with a quantitative approach. Nylon-6 nanofibers have been produced using the electrospinning method. This fiber was made with different concentrations, i.e. 20% w/w (FN1), 25% w/w (FN2), and 30% w/w (FN3). The SEM results show that the morphology of all nylon-6 nanofibers) forms perfect fibers without bead fiber. Increasing fiber concentration from 20% w/w to 30% w/w results in bigger morphology and fiber diameter. The dimensions of the FN1, FN2, and FN3 fibers are 1890 nm, 2350 nm, and 2420 nm, respectively. The results of FTIR analysis showed that the increase in the concentration of nylon-6 (b) and the electrospinning process caused a peak shift in the amide II group (CH2 bond), the carbonyl group and the CH2 stretching of the amide III group from small wave numbers to larger ones. The results of XRD characterization showed that the electrospinning process affected the changes in the XRD pattern of nylon-6 nanofiber (FN1, FN2, and FN3) in the state of semi crystal. Nylon-6 nanofibers can be used for applications in medicine, air filters, and electrode for capacitors

scholarly journals Designing Multifunctional Protective PVC Electrospun Fibers with Tunable Properties

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2086
Author(s):  
Pedro J. Rivero ◽  
Iker Rosagaray ◽  
Juan P. Fuertes ◽  
José F. Palacio ◽  
Rafael J. Rodríguez
Keyword(s):  
Fiber Diameter ◽  
Electrospinning Process ◽  
Operating Parameters ◽  
Electrospun Fibers ◽  
Polymeric Precursor ◽  
Operational Parameters ◽  
Electrospinning Technique ◽  
Coating Morphology ◽  
Hydrophobic Nature ◽  
First Time

In this work, the electrospinning technique is used for the fabrication of electrospun functional fibers with desired properties in order to show a superhydrophobic behavior. With the aim to obtain a coating with the best properties, a design of experiments (DoE) has been performed by controlling several inputs operating parameters, such as applied voltage, flow rate, and precursor polymeric concentration. In this work, the reference substrate to be coated is the aluminum alloy (60661T6), whereas the polymeric precursor is the polyvinyl chloride (PVC) which presents an intrinsic hydrophobic nature. Finally, in order to evaluate the coating morphology for the better performance, the following parameters—such as fiber diameter, surface roughness (Ra, Rq), optical properties, corrosion behavior, and wettability—have been deeply analyzed. To sum up, this is the first time that DoE has been used for the optimization of superhydrophobic or anticorrosive surfaces by using PVC precursor for the prediction of an adequate surface morphology as a function of the input operational parameters derived from electrospinning process with the aim to validate better performance.

Polycaprolactone Fiber Bundles Prepared by Self-Bundling Electrospinning

2012 ◽  
Vol 622-623 ◽  
pp. 271-275 ◽  
Author(s):  
Patcharaporn Thitiwongsawet ◽  
Tanwa Tiyajalearn ◽  
Aumnart Klinchan ◽  
Chaninporn Thanatthammachote
Keyword(s):  
Electrical Conductivity ◽  
Fiber Diameter ◽  
Average Diameter ◽  
Electrospinning Process ◽  
Fiber Bundles ◽  
Electrospun Fibers ◽  
Average Fiber Diameter ◽  
Electrospinning Technique

Polycaprolactone (PCL) fiber bundles were successfully prepared by self-bundling electrospinning technique from two different concentrations (i.e. 12% and 15% w/v) of PCL solution. Self-bundling of electrospun fibers was induced by used of a grounded needle tip at the beginning of electrospinning process. Electrical conductivity of PCL solutions were increased and average fiber diameter were decreased by addition and increasing amount of pyridinium formate (PF) at concentration of 3, 4, and 5% w/v into either 12% or 15% w/v PCL solutions. The average diameter of electrospun fibers and bundles were in range of 2.1-3.3 m and 100-120 m, respectively.

Using Orthogonal Design in Optimizing Parameters for Bubble Electrospinning of Polyvinyl Alcohol (PVA) Nanofibers

2010 ◽  
Vol 29-32 ◽  
pp. 1943-1947 ◽  
Author(s):  
Liang Dong ◽  
Wan Shou ◽  
Yong Liu ◽  
Rui Wang ◽  
Ru Dong Chen
Keyword(s):  
Polyvinyl Alcohol ◽  
Process Parameters ◽  
Applied Voltage ◽  
Orthogonal Design ◽  
Solution Concentration ◽  
Electrospinning Process ◽  
Electrospinning Technique ◽  
Array Design ◽  
Nanofiber Diameter ◽  
Lower Medium

The present work was aimed at studying the effects of process parameters on morphologies of Polyvinyl alcohol (PVA) nanofibers in a novel electrospinning technique, bubble electrospinning. The process was optimized by constructing L 9(34) orthogonal experimental array design. Three factors were investigated and nine tests were run under lower, medium and higher levels of these factors. The results showed that PVA solution concentration plays an important role in affecting the morphologies of PVA nanofibers in bubble electrospinning process. With the increase of the concentration of PVA solution, the morphologies of fibers were changed from beaded fibers to uniform cylinder fibers and the average nanofiber diameter also increased. The optimization process was 12w% for PVA solution, 30kV for applied voltage and 10cm for spinning distance.

Effect of Process Parameters on Poly(butylene adipate co-terephthalate) Nanofibers Development by Electrospinning Technique

2014 ◽  
Vol 894 ◽  
pp. 360-363 ◽  
Author(s):  
J. Prasanna ◽  
T. Monisha ◽  
V. Ranjithabala ◽  
Ravikant Gupta ◽  
E. Vijayakumar ◽  
...  
Keyword(s):  
Experimental Study ◽  
Electron Microscope ◽  
Experimental Design ◽  
Scanning Electron Microscope ◽  
Process Parameters ◽  
Fiber Diameter ◽  
Electrospinning Process ◽  
Electrospinning Technique ◽  
Optimal Setting ◽  
Scanning Electron

Electrospinning process is proved to be one of the finest fabrication techniques to produce nanofibers. This research deals with the experimental study on the effect of various process parameters of electrospinning technique such as voltage, flow rate, distance (nozzle to collector distance) and concentration, on the development of nanofibers from a new polymer, namely PBAT. Taguchis experimental design was implemented to carry out this research by conducting an L-18 orthogonal array. Taguchi method and Analysis of Variance (ANOVA) were employed to examine the effect of different process parameters simultaneously on the fabrication of nanofibers. The fibers were characterized through scanning electron microscope (SEM) for the measurement of its diameter. The experimental results indicate that all the chosen process parameters had significant influence on the fiber diameter. It was inferred that the concentration and voltage had a very notable impact on the fiber diameter. Confirmation experimental run was performed on the identified optimal setting of the process parameters.

PVA-Ketoprofen Nanofibers Manufacturing Using Electrospinning Method for Dissolution Improvement of Ketoprofen

2013 ◽  
Vol 737 ◽  
pp. 166-175 ◽  
Author(s):  
Jessie S. Pamudji ◽  
Khairurrijal ◽  
Rachmat Mauludin ◽  
Titi Sudiati ◽  
Maria Evita
Keyword(s):  
Dissolution Rate ◽  
Solid Dispersion ◽  
Flow Rate ◽  
Polymer Concentration ◽  
Electrospinning Process ◽  
X Ray Diffraction ◽  
Electrospinning Technique ◽  
Electrospinning Method ◽  
Rate Improvement

Background and purpose: Ketoprofen is an NSAIDs agent which has analgesic and anti inflammation effects. Ketoprofen is classified into class II in the biopharmaceutical classification system that has a high permeability but low solubility. Hence, the absorption rate of this substance is governed by its dissolution rate. Electrospinning is a method that combine solid dispersion technology and nanotechnology. This method can be selected to enhance the dissolution rate of active substances. The aim of this research is to improve the dissolution rate of ketoprofen through the preparation of polymeric nanofiber polivinyl alcohol (PVA) containing ketoprofen using electrospinning process. Methods: Preparation of nanofibers with various of PVA-ketoprofen ratio, flow rate, and PVA concentration in the solution were accomplished using electrospinning instrument. Casting solid dispersion film were also prepared by solvent evaporation method and used as a reference. The rates of dissolution of ketoprofen from each of nanofibers, casting films, and pure ketoprofen were conducted in HCl pH 1.2 medium at 37oC. Characterization of nanofibers was carried out using Scanning Electron Microscope (SEM) and X-ray Diffraction (XRD). Results: Nanofibers which contained of PVA-ketoprofen 1:1 in ratio w/w showed a significant improvement in dissolution (p<0.05) compared to the pure ketoprofen. Meanwhile, nanofibers obtained from a solution containing 7.5 % PVA (w/v) and 4 ml/h in flow rate showed the best dissolution rate improvement and significantly different (p<0.05) with either the casting film or the pure ketoprofen. The improvement of ketoprofen dissolution was due to the increasing of surface area of nanofiber and the change of ketoprofen from crystalline into amorphous form. Conclusion: Electrospinning technique can be used to improve the dissolution rate of ketoprofen through the PVA-ketoprofen nanofiber formation by choosing the appropriate polymer concentration and manufacturing process.

scholarly journals A novel coaxial nozzle for in-process adjustment of electrospun scaffolds’ fiber diameter

2015 ◽  
Vol 1 (1) ◽  
pp. 104-107 ◽  
Author(s):  
A. Becker ◽  
H. Zernetsch ◽  
M. Mueller ◽  
B. Glasmacher
Keyword(s):  
Fiber Diameter ◽  
Polymer Concentration ◽  
Electrospinning Process ◽  
Coaxial Electrospinning ◽  
Nozzle Design ◽  
Fiber Alignment ◽  
Scaffold Fabrication ◽  
Electrospun Scaffolds ◽  
Process Adjustment ◽  
Coaxial Nozzle

AbstractElectrospinning is a versatile method of producing micro- and nanofibers deposited in mats used as scaffolds for tissue engineering. Depending on the application, single or coaxial electrospinning can be used. Coaxial electrospinning enables the use of a broad spectrum of materials, the fabrication of hollow or core/shell fibers and an automatisation of the entire electrospinning process. In this regard, the design of coaxial nozzles plays a major role in a standardized as well as tailor-made scaffold fabrication. For this purpose an optimised coaxial nozzle has been designed and fabricated. Furthermore, tests have been carried out to validate the new nozzle design. With the use of the costum-made nozzle polymer concentration could be varied in a gradual manner. The variation in polymer concentration lead to fiber diameters between 0.75 to 3.25 μm. In addition, an increase in rotating velocity lead to an increase in fiber alignment as well as a slight decrease in fiber diameter. The demonstrated modifications of coaxial electrospinning proved to be a powerful tool for in-process adjustments of scaffold fabrication.

Alternative solvent systems for polycaprolactone nanowebs via electrospinning

2016 ◽  
Vol 47 (1) ◽  
pp. 57-70 ◽  
Author(s):  
Ipek Y Enis ◽  
Jakub Vojtech ◽  
Telem G Sadikoglu
Keyword(s):  
Formic Acid ◽  
Fiber Diameter ◽  
Polymer Concentration ◽  
Solvent System ◽  
Fiber Morphology ◽  
Solution System ◽  
Electrospinning Technique ◽  
Average Pore ◽  
Pore Analysis ◽  
Solvent Systems

In this study, polycaprolactone (PCL) was dissolved in 9:1 chloroform:ethanol mixture at 14%, 16%, 18% and 20% w/v concentrations. Then, acetic acid and formic acid were added at pre-determined amounts to 18% PCL/chloroform:ethanol solution system separately. Before production, viscosity and conductivity of prepared solutions were measured. Electrospinning technique was used for fabrication of fibrous webs. Morphology of produced webs was observed under a scanning electron microscope while fiber diameter measurements and pore analysis were realized via Image J Software System. The effect of polymer concentration and acidic solvent additions to mostly used chloroform solvent was investigated based on fiber morphology. Results indicate that the increase in polymer concentration increases the fiber diameter which leads to larger average pore area. Electrospinning of PCL with 16% to 20% polymer concentrations in chloroform:ethanol solvent system results in micro fibers. On the other hand, fiber diameter reduced from microscales to nanoscales with the addition of either acetic or formic acid. Fibers produced from PCL/chloroform:ethanol solution at 18% polymer concentration have 2.22 µm average fiber diameter, whereas 158 nm and 256 nm diameter fibers were successfully produced without a bead-like structure by 120 µl of acetic and formic acid additions to the same solution system.

scholarly journals Surface Morphology Analysis and Mechanical Characterization of Electrospun Nanofibrous Structure

2016 ◽  
Vol 701 ◽  
pp. 89-93 ◽  
Author(s):  
Dannee Wong ◽  
Andri Andriyana ◽  
Bee Chin Ang ◽  
Ying Rui Chan ◽  
Jacky Jia Li Lee ◽  
...  
Keyword(s):  
Surface Morphology ◽  
Polyvinylidene Fluoride ◽  
Mechanical Characterization ◽  
Polymer Concentration ◽  
Real Life ◽  
Electrospinning Process ◽  
Electrospinning Technique ◽  
Morphology Analysis ◽  
Nanofibrous Structure

The extraordinary properties of nanofibrous structure have gained ever-increasing appeal as an attractive candidate in a myriad of applications, especially for the water filtration. This type of structure has permeability due to its porous structure. Electrospinning is one of the most viable approaches in fabricating nanofibrous web that exhibits novel and outstanding performance in membrane separation as compared to those produced through conventional methods. Thus, the optimization of electrospinning processes is actively pursued by many researchers in order to obtain the best structure suitable for real-life applications. In this study, the surface morphology analysis and mechanical characterization of nanofibrous structure are addressed. For this purpose, polyvinylidene fluoride (PVDF) is considered. The polymeric nanofibrous structures are fabricated through electrospinning technique. Parameters such as polymer concentration and applied voltage for electrospinning process were varied and the resulting morphology of the structure were observed using SEM. In addition, the macroscopic mechanical responses of the structure were probed by means of tensile tests with special attention given to membrane anisotropy and behavior under cyclic loading.

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