scholarly journals Synthesis of Copper Oxide Nanoparticles Using Plant Leaf Extract of Catha edulis and Its Antibacterial Activity

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Worku Wubet Andualem ◽  
Fedlu Kedir Sabir ◽  
Endale Tsegaye Mohammed ◽  
Hadgu Hailekiros Belay ◽  
Bedasa Abdisa Gonfa
Keyword(s):  
Copper Oxide ◽  
Low Cost ◽  
Copper Nitrate ◽  
Solution Concentration ◽  
Antimicrobial Activities ◽  
Copper Oxide Nanoparticles ◽  
Green Technology ◽  
Catha Edulis ◽  
X Ray ◽  
Cuo Nps

Development of green technology is generating interest of researchers towards ecofriendly and low-cost methods for biosynthesis of nanoparticles (NPs). In this study, copper oxide (CuO) NPs were synthesized using a copper nitrate trihydrate precursor and Catha edulis leaves extract as a reducing and capping agent during the synthesis. The biosynthesized CuO NPs were characterized using an X-ray diffractometer (XRD), scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDS), transmission electron microscope (TEM), Ultraviolet visible spectroscopy (UV-Vis), and Fourier transform infrared (FTIR) spectroscopy. XRD characterization confirmed that the biosynthesized CuO NPs possessed a good crystalline nature which perfectly matched the monoclinic structure of bulk CuO. Furthermore, the results obtained from SEM and TEM showed that the biosynthesized CuO NPs were spherical in shape. EDS characterization of the biosynthesized NPs also indicated that the reaction product was composed of highly pure CuO NPs. Moreover, the antimicrobial activities of different concentrations of CuO NPs synthesized using Catha edulis extract were also tested. Accordingly, the result showed that the highest zone of inhibitions measured were for CuO NPs synthesized using 1 : 2 ratios at 40 mg/ml solution concentration and observed to be 22 ± 0.01 mm, 24 ± 0.02 mm, 32 ± 0.02 mm, and 29 ± 0.03 mm for S. aureus, S. pyogenes, E. coli, and K. pneumonia, respectively.

scholarly journals Green Synthesis of Copper Oxide Nanoparticles Using Aerva javanica Leaf Extract and Their Characterization and Investigation of In Vitro Antimicrobial Potential and Cytotoxic Activities

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Fozia Amin ◽  
Fozia ◽  
Baharullah Khattak ◽  
Amal Alotaibi ◽  
Muhammad Qasim ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Fungal Pathogens ◽  
Leaf Extract ◽  
Antimicrobial Activities ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Antimicrobial Potential ◽  
Cuo Nps

The development of green technology is creating great interest for researchers towards low-cost and environmentally friendly methods for the synthesis of nanoparticles. Copper oxide nanoparticles (CuO-NPs) attracted many researchers due to their electric, catalytic, optical, textile, photonic, monofluid, and pharmacological activities that depend on the shape and size of the nanoparticles. This investigation aims copper oxide nanoparticles synthesis using Aerva javanica plant leaf extract. Characterization of copper oxide nanoparticles synthesized by green route was performed by three different techniques: X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR) Spectroscopy, and Scanning Electron Microscopy (SEM). X-ray diffraction (XRD) reveals the crystalline morphology of CuO-NPs and the average crystal size obtained is 15 nm. SEM images showed the spherical nature of the particles and size is lying in the 15–23 nm range. FTIR analysis confirms the functional groups of active components present in the extract which are responsible for reducing and capping agents for the synthesis of CuO-NPs. The synthesized CuO-NPs were studied for their antimicrobial potential against different bacterial as well as fungal pathogens. The results indicated that CuO-NPs show maximum antimicrobial activities against all the selected bacterial and fungal pathogens. Antimicrobial activities of copper oxide nanoparticles were compared with standard drugs Norfloxacin and amphotericin B antibiotics. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of copper oxide nanoparticles were 128 μg/mL against all selected bacterial pathogens. MIC of fungus and minimum fungicidal concentration (MFC) of CuO-NPs were 160 μg/mL. Thus, CuO-NPs can be utilized as a broad-spectrum antimicrobial agent. The cytotoxic activity of the synthesized CuO-NPs suggested that toxicity was negligible at concentrations below 60 μg/mL.

scholarly journals Synthesis, Characterization, and Antimicrobial Activity of Copper Oxide Nanoparticles

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Maqusood Ahamed ◽  
Hisham A. Alhadlaq ◽  
M. A. Majeed Khan ◽  
Ponmurugan Karuppiah ◽  
Naif A. Al-Dhabi
Keyword(s):  
Antimicrobial Activity ◽  
Electron Microscope ◽  
Copper Oxide ◽  
Field Emission ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Xrd Pattern ◽  
X Ray ◽  
Cuo Nps

We studied the structural and antimicrobial properties of copper oxide nanoparticles (CuO NPs) synthesized by a very simple precipitation technique. Copper (II) acetate was used as a precursor and sodium hydroxide as a reducing agent. X-ray diffraction patter (XRD) pattern showed the crystalline nature of CuO NPs. Field emission scanning electron microscope (FESEM) and field emission transmission electron microscope (FETEM) demonstrated the morphology of CuO NPs. The average diameter of CuO NPs calculated by TEM and XRD was around 23 nm. Energy dispersive X-ray spectroscopy (EDS) spectrum and XRD pattern suggested that prepared CuO NPs were highly pure. CuO NPs showed excellent antimicrobial activity against various bacterial strains (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumonia,Enterococcus faecalis,Shigella flexneri,Salmonella typhimurium,Proteus vulgaris,andStaphylococcus aureus). Moreover,E. coliandE. faecalisexhibited the highest sensitivity to CuO NPs whileK. pneumoniawas the least sensitive. Possible mechanisms of antimicrobial activity of CuO NPs should be further investigated.

scholarly journals Facile Synthesis of Copper Oxide Nanoparticles via Electrospinning

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Abdullah Khalil ◽  
Mustapha Jouiad ◽  
Marwan Khraisheh ◽  
Raed Hashaikeh
Keyword(s):  
Copper Oxide ◽  
Large Scale ◽  
Low Cost ◽  
Copper Acetate ◽  
Electrospun Nanofibers ◽  
Copper Oxide Nanoparticles ◽  
One Dimensional ◽  
Cuo Nps ◽  
Novel Approach ◽  
Transmission Electron

A novel approach for synthesizing copper oxide (CuO) nanoparticles (NPs) through electrospinning is reported. The approach is based on producing rough and discontinuous electrospun nanofibers from a precursor based on copper acetate salt and polyvinyl alcohol (PVA) polymer. Selectively removing the polymeric phase from the fibers produced highly rough CuO nanofibers, which were composed of NPs that are weakly held together in a one-dimensional (1D) manner. Sonication in a suitable liquid under controlled conditions completely disintegrated the nanofibers into NPs, resulting in the formation of uniform CuO NPs suspension. Aberration corrected high resolution transmission electron microscope (HRTEM) showed that the obtained NPs are highly crystalline and nearly sphere-like with a diameter of 30 to 70 nm. Thus, electrospinning, which is a low cost and industrially scalable technique, can also be employed for economic and large scale synthesis of NPs.

Biosynthesis of Copper Oxide Nanoparticles Using Lactobacillus casei Subsp. Casei and its Anticancer and Antibacterial Activities

2020 ◽  
Vol 16 (1) ◽  
pp. 101-111 ◽  
Author(s):  
Mehri Kouhkan ◽  
Parinaz Ahangar ◽  
Leila Ashrafi Babaganjeh ◽  
Maryam Allahyari-Devin
Keyword(s):  
Copper Oxide ◽  
Cancer Cells ◽  
Lactobacillus Casei ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
No Production ◽  
Cytotoxic Effects ◽  
Gram Negative ◽  
X Ray ◽  
Cuo Nps

Background:The present study reveals the synthesis of copper oxide nanoparticles (CuO NPs) by probiotic bacteria (Lactobacillus casei subsp. casei) and demonstrates the cytotoxic effects of these nanoparticles against gram negative and positive bacteria and cancer cell lines.Methods:The CuO NPs are biosynthesized from Lactobacillus casei subsp. casei (L. casei) in an eco-friendly and cost-effective process. These nanoparticles are characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and transmittance electron microscope (TEM) analysis. The antibacterial activity is examined by Well-diffusion, minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) assays using Broth microdilution. Anticancer effects of these nanoparticles are evaluated by methyl thiazolyl diphenyl-tetrazolium bromide (MTT) assay and Griess test.Results:Our results confirm the biosynthesis of CuO NPs from L. casei. Antibacterial assays demonstrate that treatment of gram-negative and gram-positive bacteria with CuO NPs inhibits the growth of these bacteria. Furthermore, the cell viability of human cancer cells decreases while treated by nanoparticles. These nanoparticles increase nitric oxide (NO) secretion determined by NO production measurement.Conclusion:These results suggest that CuO NPs may exert antibacterial effects as well as cytotoxic effects on cancer cells by suppressing their growth, increasing the oxidative stress and inducing apoptosis.

Copper oxide nanoparticles: an antidermatophytic agent for Trichophyton spp.

2015 ◽  
Vol 4 (5) ◽  
Author(s):  
Rajesh Kumar ◽  
Shashi Kant Shukla ◽  
Anand Pandey ◽  
Sanjeev Kumar Srivastava ◽  
Anupam Dikshit
Keyword(s):  
Copper Oxide ◽  
Transition Metal Oxides ◽  
Pathogenic Bacteria ◽  
Copper Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Cuo Nps ◽  
Crystalline Nature ◽  
Prevalent Species

AbstractCopper oxide (CuO) is one of the most important transition metal oxides due to its unique properties. It is used in various technological applications such as high critical temperature, superconductors, gas sensors, in photoconductive applications and so on. Recently, it has been used as an antimicrobial agent against various pathogenic bacteria. In the present investigation, we studied the structural and antidermatophytic properties of CuO nanoparticles (NPs) synthesized by a precipitation technique. Copper sulfate was used as a precursor and sodium hydroxide as a reducing agent. Scanning electron microscopy (SEM) showed flower-shaped CuO NPs and X-ray diffraction (XRD) pattern showed the crystalline nature of CuO NPs. These NPs were evaluated against two prevalent species of dermatophytes, i.e.

scholarly journals Facial Eco-Friendly Synthesis of Copper Oxide Nanoparticles Using Chia Seeds Extract and Evaluation of Its Electrochemical Activity

Processes ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 2027
Author(s):  
Noha Al-Qasmi
Keyword(s):  
Copper Oxide ◽  
Photoelectron Spectroscopy ◽  
Electrochemical Impedance ◽  
Analytical Techniques ◽  
Copper Oxide Nanoparticles ◽  
Seed Extract ◽  
Oxide Nanoparticles ◽  
X Ray ◽  
Cuo Nps ◽  
Chia Seed

In the current study, copper oxide nanoparticles (CuO NPs) were synthesized using chia seed extract in a simple, rapid, and eco-friendly manner for the first time. The synthesized CuO NPs were characterized using different analytical techniques. The images of field emission scanning electron microscopy revealed that the CuO NPs were triangular and pyramid in structure, with a mean particle size of 61.5 nm. The absorption peak of the synthesized CuO NPs was measured using ultraviolet-visible spectroscopy and was recorded at a wavelength of 291 nm. The results of energy-dispersive X-ray analysis confirmed that the CuO NPs synthesized using chia seed extract yielded high-purity CuO NPs. Moreover, the X-ray diffraction analysis indicated the highly crystalline nature of the CuO NPs, and the X-ray photoelectron spectroscopy results indicated that the CuO NPs were prepared successfully. Additionally, electrochemical impedance spectroscopy measurements revealed excellent electrocatalytic conductivity and fast electron transfer at the electrode/electrolyte interface of the synthesized CuO NP-modified glassy carbon electrode.

scholarly journals Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 564
Author(s):  
Devanthiran Letchumanan ◽  
Sophia P. M. Sok ◽  
Suriani Ibrahim ◽  
Noor Hasima Nagoor ◽  
Norhafiza Mohd Arshad
Keyword(s):  
Copper Oxide ◽  
Low Cost ◽  
Metal Oxide Nanoparticles ◽  
Cost Effective ◽  
Copper Oxide Nanoparticles ◽  
Synthesis Process ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Metal Metal ◽  
Reducing Properties

Plants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows the production of the desired NPs in different sizes and shapes by manipulating parameters during the synthesis process. The most commonly used metals and oxides are gold (Au), silver (Ag), and copper (Cu). Among these, Cu is a relatively low-cost metal that is more cost-effective than Au and Ag. In this review, we present an overview and current update of plant-mediated Cu/copper oxide (CuO) NPs, including their synthesis, medicinal applications, and mechanisms. Furthermore, the toxic effects of these NPs and their efficacy compared to commercial NPs are reviewed. This review provides an insight into the potential of developing plant-based Cu/CuO NPs as a therapeutic agent for various diseases in the future.

ANTIBIOTIC PROFILE AND ANTIBACTERIAL ACTIVITY OF COPPER OXIDE NANOPARTICLES AGAINST Pseudomonas fluorescens ISOLATED FROM WOUND INFECTION

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Haider Qassim Raheem ◽  
Takwa S. Al-meamar ◽  
Anas M. Almamoori
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Pseudomonas Fluorescens ◽  
Wide Spectrum ◽  
Copper Oxide Nanoparticles ◽  
Morphological Properties ◽  
Clinical Samples ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Disk Diffusion Assay

Fifty specimens were collected from wound patients who visited Al-Hilla Teaching Hospital. The samples were grown on Blood and MacConkey agar for 24-48 hr at 37oC. The bacterial isolates which achieved as a pure and predominant growth from clinical samples as Pseudomonas fluorescens, were identified using morphological properties and Vitek2 system. The anti-bacterial activity of copper oxide nanoparticles (CuO NPs) against was tested by (disk diffusion assay) using dilutions of (400, 200, 100, 50, 25, and 12.5‎µ‎g/ml). The (MIC and MBC) of each isolate was determined. CuO NPs shows wide spectrum antibacterial activity against tested bacteria with rise zone of inhibition diameter that is proportionate with the increase in nanoparticle concentration. The MIC of CuO NPs extended from 100-200‎µ‎g/ml and the MBC ranged from 200-400‎µ‎g/ml. The antibiotic profile was determined by Viteck 2 compact system (Biomérieux). CuO NPs‎ found highly effective and safe in P. fluorescens wounds infections comparing with used antibiotics.

A Facile Synthesis of Cu2O and CuO Nanoparticles Via Sonochemical Assisted Method

2018 ◽  
Vol 15 (2) ◽  
pp. 209-213 ◽  
Author(s):  
Sathish Mohan Botsa ◽  
Ramadevi Dharmasoth ◽  
Keloth Basavaiah
Keyword(s):  
Diffuse Reflectance Spectroscopy ◽  
Cupric Oxide ◽  
Copper Acetate ◽  
Chemical Properties ◽  
Copper Oxide Nanoparticles ◽  
Reducing Agents ◽  
Sonochemical Method ◽  
Phase Purity ◽  
X Ray ◽  
Cuo Nps

Background: During past two decades, functional nanomaterials have received great attention for many technological applications such as catalysis, energy, environment, medical and sensor due to their unique properties at nanoscale. However, copper oxide nanoparticles (NPs) such as CuO and Cu2O have most widely investigated for many potential applications due to their wide bandgap, high TC, high optical absorption and non-toxic in nature. The physical and chemical properties of CuO and Cu2O NPs are critically depending on their size, morphology and phase purity. Therefore, lots of efforts have been done to prepare phase CuO and Cu2O NPs with different morphology and size. Method: The synthesis of cupric oxide (CuO) and cuprous oxide (Cu2O) NPs using copper acetate as a precursor by varying the reducing agents such as hydrazine sulphate and hydrazine hydrate via sonochemical method. The phase, morphology and crystalline structure of a prepared CuO and Cu2O NPs were investigated by X-ray diffraction (XRD), Fourier transform infrared (FTIR), Field emission scanning electron microscopy (FESEM), Energy dispersive X-ray (EDS) and UV-Visible Diffuse reflectance spectroscopy (DRS). Results: The phase of NPs was tuned as a function of reducing agents.XRD patterns confirmed the formation of pure phase crystalline CuO and Cu2O NPs. FTIR peak at 621 cm-1 confirmed Cu(I)-O vibrations, while CuO vibrations confirmed by the presence of two peaks at 536 and 586 cm-1. Further investigation was done by Raman, which clearly indicates the presence of peaks at 290, 336, 302 cm-1 and 173, 241 cm-1 for CuO and Cu2O NPs, respectively. The FESEM images revealed rod-like morphology of the CuO NPs while octahedral like shape for Cu2O NPs. The presence of elemental Cu and O in stoichiometric ratios in EDS spectra confirms the formation of both CuO and Cu2O NPs. In summary, CuO and Cu2O NPs were successfully synthesized by a sonochemical method using copper acetate as a precursor at different reducing agents. The bandgap of CuO and Cu2O NPs was 2.38 and 1.82, respectively. Furthermore, the phase purity critically depends on reducing agents.

scholarly journals Green copper oxide nanoparticles for lead, nickel, and cadmium removal from contaminated water

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alaa El Din Mahmoud ◽  
Khairia M. Al-Qahtani ◽  
Sahab O. Alflaij ◽  
Salma F. Al-Qahtani ◽  
Faten A. Alsamhan
Keyword(s):  
Experimental Data ◽  
Copper Oxide ◽  
Copper Oxide Nanoparticles ◽  
Bet Surface Area ◽  
Oxide Nanoparticles ◽  
Cadmium Removal ◽  
Cuo Nps ◽  
Pseudo Second Order ◽  
Isotherm And Kinetic Models ◽  
Lead Nickel

AbstractEnvironmentally friendly copper oxide nanoparticles (CuO NPs) were prepared with a green synthesis route without using hazardous chemicals. Hence, the extracts of mint leaves and orange peels were utilized as reducing agents to synthesize CuO NPs-1 and CuO NPs-2, respectively. The synthesized CuO NPs nanoparticles were characterized using scanning electron microscopy (SEM), Energy Dispersive X-ray Analysis (EDX), BET surface area, Ultraviolet–Visible spectroscopy (UV–Vis), and Fourier Transform Infrared Spectroscopy (FT-IR). Various parameters of batch experiments were considered for the removal of Pb(II), Ni(II), and Cd(II) using the CuO NPs such as nanosorbent dose, contact time, pH, and initial metal concentration. The maximum uptake capacity (qm) of both CuO NPs-1 and CuO NPs-2 followed the order of Pb(II) > Ni(II) > Cd(II). The optimum qm of CuO NPs were 88.80, 54.90, and 15.60 mg g−1 for Pb(II), Ni(II), and Cd(II), respectively and occurred at sorbent dose of 0.33 g L−1 and pH of 6. Furthermore, isotherm and kinetic models were applied to fit the experimental data. Freundlich models (R2 > 0.97) and pseudo-second-order model (R2 > 0.96) were fitted well to the experimental data and the equilibrium of metal adsorption occurred within 60 min.

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