scholarly journals Synthesis, Characterization, and Antimicrobial Activity of Copper Oxide Nanoparticles

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Maqusood Ahamed ◽  
Hisham A. Alhadlaq ◽  
M. A. Majeed Khan ◽  
Ponmurugan Karuppiah ◽  
Naif A. Al-Dhabi
Keyword(s):  
Antimicrobial Activity ◽  
Electron Microscope ◽  
Copper Oxide ◽  
Field Emission ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Xrd Pattern ◽  
X Ray ◽  
Cuo Nps

We studied the structural and antimicrobial properties of copper oxide nanoparticles (CuO NPs) synthesized by a very simple precipitation technique. Copper (II) acetate was used as a precursor and sodium hydroxide as a reducing agent. X-ray diffraction patter (XRD) pattern showed the crystalline nature of CuO NPs. Field emission scanning electron microscope (FESEM) and field emission transmission electron microscope (FETEM) demonstrated the morphology of CuO NPs. The average diameter of CuO NPs calculated by TEM and XRD was around 23 nm. Energy dispersive X-ray spectroscopy (EDS) spectrum and XRD pattern suggested that prepared CuO NPs were highly pure. CuO NPs showed excellent antimicrobial activity against various bacterial strains (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumonia,Enterococcus faecalis,Shigella flexneri,Salmonella typhimurium,Proteus vulgaris,andStaphylococcus aureus). Moreover,E. coliandE. faecalisexhibited the highest sensitivity to CuO NPs whileK. pneumoniawas the least sensitive. Possible mechanisms of antimicrobial activity of CuO NPs should be further investigated.

scholarly journals Green Synthesis of Copper Oxide Nanoparticles Using Aerva javanica Leaf Extract and Their Characterization and Investigation of In Vitro Antimicrobial Potential and Cytotoxic Activities

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Fozia Amin ◽  
Fozia ◽  
Baharullah Khattak ◽  
Amal Alotaibi ◽  
Muhammad Qasim ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Fungal Pathogens ◽  
Leaf Extract ◽  
Antimicrobial Activities ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Antimicrobial Potential ◽  
Cuo Nps

The development of green technology is creating great interest for researchers towards low-cost and environmentally friendly methods for the synthesis of nanoparticles. Copper oxide nanoparticles (CuO-NPs) attracted many researchers due to their electric, catalytic, optical, textile, photonic, monofluid, and pharmacological activities that depend on the shape and size of the nanoparticles. This investigation aims copper oxide nanoparticles synthesis using Aerva javanica plant leaf extract. Characterization of copper oxide nanoparticles synthesized by green route was performed by three different techniques: X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR) Spectroscopy, and Scanning Electron Microscopy (SEM). X-ray diffraction (XRD) reveals the crystalline morphology of CuO-NPs and the average crystal size obtained is 15 nm. SEM images showed the spherical nature of the particles and size is lying in the 15–23 nm range. FTIR analysis confirms the functional groups of active components present in the extract which are responsible for reducing and capping agents for the synthesis of CuO-NPs. The synthesized CuO-NPs were studied for their antimicrobial potential against different bacterial as well as fungal pathogens. The results indicated that CuO-NPs show maximum antimicrobial activities against all the selected bacterial and fungal pathogens. Antimicrobial activities of copper oxide nanoparticles were compared with standard drugs Norfloxacin and amphotericin B antibiotics. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of copper oxide nanoparticles were 128 μg/mL against all selected bacterial pathogens. MIC of fungus and minimum fungicidal concentration (MFC) of CuO-NPs were 160 μg/mL. Thus, CuO-NPs can be utilized as a broad-spectrum antimicrobial agent. The cytotoxic activity of the synthesized CuO-NPs suggested that toxicity was negligible at concentrations below 60 μg/mL.

Biosynthesis of Copper Oxide Nanoparticles Using Lactobacillus casei Subsp. Casei and its Anticancer and Antibacterial Activities

2020 ◽  
Vol 16 (1) ◽  
pp. 101-111 ◽  
Author(s):  
Mehri Kouhkan ◽  
Parinaz Ahangar ◽  
Leila Ashrafi Babaganjeh ◽  
Maryam Allahyari-Devin
Keyword(s):  
Copper Oxide ◽  
Cancer Cells ◽  
Lactobacillus Casei ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
No Production ◽  
Cytotoxic Effects ◽  
Gram Negative ◽  
X Ray ◽  
Cuo Nps

Background:The present study reveals the synthesis of copper oxide nanoparticles (CuO NPs) by probiotic bacteria (Lactobacillus casei subsp. casei) and demonstrates the cytotoxic effects of these nanoparticles against gram negative and positive bacteria and cancer cell lines.Methods:The CuO NPs are biosynthesized from Lactobacillus casei subsp. casei (L. casei) in an eco-friendly and cost-effective process. These nanoparticles are characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and transmittance electron microscope (TEM) analysis. The antibacterial activity is examined by Well-diffusion, minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) assays using Broth microdilution. Anticancer effects of these nanoparticles are evaluated by methyl thiazolyl diphenyl-tetrazolium bromide (MTT) assay and Griess test.Results:Our results confirm the biosynthesis of CuO NPs from L. casei. Antibacterial assays demonstrate that treatment of gram-negative and gram-positive bacteria with CuO NPs inhibits the growth of these bacteria. Furthermore, the cell viability of human cancer cells decreases while treated by nanoparticles. These nanoparticles increase nitric oxide (NO) secretion determined by NO production measurement.Conclusion:These results suggest that CuO NPs may exert antibacterial effects as well as cytotoxic effects on cancer cells by suppressing their growth, increasing the oxidative stress and inducing apoptosis.

Copper oxide nanoparticles: an antidermatophytic agent for Trichophyton spp.

2015 ◽  
Vol 4 (5) ◽  
Author(s):  
Rajesh Kumar ◽  
Shashi Kant Shukla ◽  
Anand Pandey ◽  
Sanjeev Kumar Srivastava ◽  
Anupam Dikshit
Keyword(s):  
Copper Oxide ◽  
Transition Metal Oxides ◽  
Pathogenic Bacteria ◽  
Copper Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Cuo Nps ◽  
Crystalline Nature ◽  
Prevalent Species

AbstractCopper oxide (CuO) is one of the most important transition metal oxides due to its unique properties. It is used in various technological applications such as high critical temperature, superconductors, gas sensors, in photoconductive applications and so on. Recently, it has been used as an antimicrobial agent against various pathogenic bacteria. In the present investigation, we studied the structural and antidermatophytic properties of CuO nanoparticles (NPs) synthesized by a precipitation technique. Copper sulfate was used as a precursor and sodium hydroxide as a reducing agent. Scanning electron microscopy (SEM) showed flower-shaped CuO NPs and X-ray diffraction (XRD) pattern showed the crystalline nature of CuO NPs. These NPs were evaluated against two prevalent species of dermatophytes, i.e.

Synthesis, characterization and antibacterial activity of copper oxide nanoparticles

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Hemalatha D ◽  
Shanmugapriya B
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Copper Chloride ◽  
Chemical Precipitation ◽  
Copper Oxide Nanoparticles ◽  
Precipitation Method ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
X Ray ◽  
Chloride Dihydrate

Copper oxide nanoparticles were synthesized by Chemical Precipitation Method using Copper Chloride Dihydrate (CuCl2. 2H2O), Sodium hydroxide (NaOH) as a precipitating agent. The Synthesized Copper Oxide nanoparticles were characterized by X-ray diffraction (XRD), Scanning Electron Microscope (SEM), Energy Dispersive X-ray (EDX) Spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR). The Antibacterial activity of copper Oxide nanoparticles was tested against both gram positive and negative bacteria. In XRD, the crystal size and dislocation density of Copper Oxide nanoparticles were calculated, Element’s purity was determined by EDX spectra. The SEM image confirms the presence of homogeneous spherical distribution of copper oxide nanoparticles. The nanoparticles shows interactions between copper and oxygen atoms were supported by FTIR studies. Copper Oxide nanoparticles have exhibits good antibacterial activity against Klebsiella pneumonia, Escherichia coli,Staphylococcus, and Bacillus cereus.

Green Synthesis of Copper Oxide Nanoparticles (CuO NPs) From Aqueous Extract of Seeds of Eletteria Cardamomum and Its Antimicrobial Activity against Pathogens

2020 ◽  
Vol 09 ◽  
Author(s):  
Akshaya Venkatramanan ◽  
Akila Ilangovan ◽  
Pakutharivu Thangarajan ◽  
Anitha Saravanan ◽  
Balachandar M
Keyword(s):  
Antimicrobial Activity ◽  
Copper Oxide ◽  
Green Synthesis ◽  
Aqueous Extract ◽  
Dye Sensitized Solar Cells ◽  
Copper Oxide Nanoparticles ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Vis Spectroscopy

Background: The Nanomaterials/Nanoparticles are of great interest today because of their small size and large surface area, modular and easily tunable morphology and size. Copper oxide (CuO) nanoparticles are widely used in dye-sensitized solar cells (DSSCs). Research on the synthesis and properties of metallic nanomaterials is a growing field of nanotechnology due to the use of nanoparticles in the scientific, technical, pharmaceutical, and biomedical fields. Green synthesis is an emerging technology for the production of nanoparticles due to its many advantages over traditional physical processes and the method of chemical synthesis. Methods: In this study, we report the cost-effective, long-lasting, stable, and regenerative aqueous extract of Eletteria cardamom seeds to target the synthesis of copper oxide nanoparticles (CuO NPs). This method is completely green, free from toxic and harmful solvents. CuO NPs were synthesized from a cupric nitrate mixture and the aqueous extracts of Eletteria cardamom seeds were kept at room temperature for 24 h. CuO NPs were characterized using UV-visible spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), dynamic light scattering (DLS), and Fourier Transfer infra-red spectroscopy (FTIR) analyzes. UV - Vis spectroscopy revealed the presence of CuO NPs. Results: SEM images stated that the particles were spherical and ranged in size from 1–100nm. FTIR spectra of control (seed extract) and synthesized CuO NPs identify functional groups of active components. In addition, the synthesized CuO NPs were tested for antimicrobial activity by standard disc diffusion method. Conclusion: Nanoparticles found that Escherichia coli and Staphylococcus aureus resistant areas were observed around each well with antimicrobial activity against disease-causing pathogenic strains.

scholarly journals Facial Eco-Friendly Synthesis of Copper Oxide Nanoparticles Using Chia Seeds Extract and Evaluation of Its Electrochemical Activity

Processes ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 2027
Author(s):  
Noha Al-Qasmi
Keyword(s):  
Copper Oxide ◽  
Photoelectron Spectroscopy ◽  
Electrochemical Impedance ◽  
Analytical Techniques ◽  
Copper Oxide Nanoparticles ◽  
Seed Extract ◽  
Oxide Nanoparticles ◽  
X Ray ◽  
Cuo Nps ◽  
Chia Seed

In the current study, copper oxide nanoparticles (CuO NPs) were synthesized using chia seed extract in a simple, rapid, and eco-friendly manner for the first time. The synthesized CuO NPs were characterized using different analytical techniques. The images of field emission scanning electron microscopy revealed that the CuO NPs were triangular and pyramid in structure, with a mean particle size of 61.5 nm. The absorption peak of the synthesized CuO NPs was measured using ultraviolet-visible spectroscopy and was recorded at a wavelength of 291 nm. The results of energy-dispersive X-ray analysis confirmed that the CuO NPs synthesized using chia seed extract yielded high-purity CuO NPs. Moreover, the X-ray diffraction analysis indicated the highly crystalline nature of the CuO NPs, and the X-ray photoelectron spectroscopy results indicated that the CuO NPs were prepared successfully. Additionally, electrochemical impedance spectroscopy measurements revealed excellent electrocatalytic conductivity and fast electron transfer at the electrode/electrolyte interface of the synthesized CuO NP-modified glassy carbon electrode.

ANTIBIOTIC PROFILE AND ANTIBACTERIAL ACTIVITY OF COPPER OXIDE NANOPARTICLES AGAINST Pseudomonas fluorescens ISOLATED FROM WOUND INFECTION

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Haider Qassim Raheem ◽  
Takwa S. Al-meamar ◽  
Anas M. Almamoori
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Pseudomonas Fluorescens ◽  
Wide Spectrum ◽  
Copper Oxide Nanoparticles ◽  
Morphological Properties ◽  
Clinical Samples ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Disk Diffusion Assay

Fifty specimens were collected from wound patients who visited Al-Hilla Teaching Hospital. The samples were grown on Blood and MacConkey agar for 24-48 hr at 37oC. The bacterial isolates which achieved as a pure and predominant growth from clinical samples as Pseudomonas fluorescens, were identified using morphological properties and Vitek2 system. The anti-bacterial activity of copper oxide nanoparticles (CuO NPs) against was tested by (disk diffusion assay) using dilutions of (400, 200, 100, 50, 25, and 12.5‎µ‎g/ml). The (MIC and MBC) of each isolate was determined. CuO NPs shows wide spectrum antibacterial activity against tested bacteria with rise zone of inhibition diameter that is proportionate with the increase in nanoparticle concentration. The MIC of CuO NPs extended from 100-200‎µ‎g/ml and the MBC ranged from 200-400‎µ‎g/ml. The antibiotic profile was determined by Viteck 2 compact system (Biomérieux). CuO NPs‎ found highly effective and safe in P. fluorescens wounds infections comparing with used antibiotics.

Green synthesis of copper oxide nanoparticles using aloe vera extract

2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Hemalatha D ◽  
Saraswath S
Keyword(s):  
Copper Oxide ◽  
Biomedical Application ◽  
Aloe Vera ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Cupric Sulfate ◽  
X Ray Diffraction ◽  
Fouriertransform Infrared Spectroscopy ◽  
Effective Use

In material science, green method for synthesis of nanomaterials is feasible, cheaper and eco-friendly protocol. To accomplish this phenomenon, present study was aimed to synthesize Copper oxide nanoparticles using leaf extract of Aloevera with two different precursors CuCl2.2H2O (Cupric chloride) and CuSo4.5H2O (Cupric sulfate). The extraction of Aloevera is employed as reducing and stabilizing agent for this synthesis.Copper oxide Nanoparticles is effective use of biomedical application due to their antibacterial function. The synthesized Copper oxide nanoparticles were characterized by X-Ray Diffraction Spectroscopy (XRD), Energy Dispersive Spectroscopy (EDX), FourierTransform Infrared Spectroscopy (FT- IR) and Scanning Electron Microscope(SEM). XRD studies reveal the crystallographic nature of Copper oxide nanoparticles. Furthermore the Copper oxide nanoparticles have good Antibacterial activity against both gram negative (E.Coli, Klebsiella pneumonia) and gram positive (Bacillus cereus, Staphylococcus aureus)bacteria.

scholarly journals Green copper oxide nanoparticles for lead, nickel, and cadmium removal from contaminated water

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alaa El Din Mahmoud ◽  
Khairia M. Al-Qahtani ◽  
Sahab O. Alflaij ◽  
Salma F. Al-Qahtani ◽  
Faten A. Alsamhan
Keyword(s):  
Experimental Data ◽  
Copper Oxide ◽  
Copper Oxide Nanoparticles ◽  
Bet Surface Area ◽  
Oxide Nanoparticles ◽  
Cadmium Removal ◽  
Cuo Nps ◽  
Pseudo Second Order ◽  
Isotherm And Kinetic Models ◽  
Lead Nickel

AbstractEnvironmentally friendly copper oxide nanoparticles (CuO NPs) were prepared with a green synthesis route without using hazardous chemicals. Hence, the extracts of mint leaves and orange peels were utilized as reducing agents to synthesize CuO NPs-1 and CuO NPs-2, respectively. The synthesized CuO NPs nanoparticles were characterized using scanning electron microscopy (SEM), Energy Dispersive X-ray Analysis (EDX), BET surface area, Ultraviolet–Visible spectroscopy (UV–Vis), and Fourier Transform Infrared Spectroscopy (FT-IR). Various parameters of batch experiments were considered for the removal of Pb(II), Ni(II), and Cd(II) using the CuO NPs such as nanosorbent dose, contact time, pH, and initial metal concentration. The maximum uptake capacity (qm) of both CuO NPs-1 and CuO NPs-2 followed the order of Pb(II) > Ni(II) > Cd(II). The optimum qm of CuO NPs were 88.80, 54.90, and 15.60 mg g−1 for Pb(II), Ni(II), and Cd(II), respectively and occurred at sorbent dose of 0.33 g L−1 and pH of 6. Furthermore, isotherm and kinetic models were applied to fit the experimental data. Freundlich models (R2 > 0.97) and pseudo-second-order model (R2 > 0.96) were fitted well to the experimental data and the equilibrium of metal adsorption occurred within 60 min.

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