scholarly journals Photothermal Effect of Superparamagnetic Fe3O4 Nanoparticles Irradiated by Near-Infrared Laser

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Shawei Fu ◽  
Yuchun Man ◽  
Fuquan Jia
Keyword(s):  
Cancer Treatment ◽  
Power Density ◽  
Infrared Absorption ◽  
Fe3o4 Nanoparticles ◽  
Near Infrared ◽  
Infrared Laser ◽  
Photothermal Effect ◽  
Transduction Efficiency ◽  
Large Power ◽  
Fe3o4 Nps

Fe3O4 nanoparticles (NPs) have been widely used in biomedicine due to their unique magnetism, biocompatibility, and biodegradability. Magnetic hyperthermia of Fe3O4 NPs for cancer treatment has attracted more attention. However, it could interfere with magnetic field-sensitive devices of patients, such as pacemakers. Therefore, it is necessary to find a new method for clinical therapy. In this study, the superparamagnetic Fe3O4 NPs were fabricated. Visible-near-infrared absorption spectra indicated that the Fe3O4 NPs have near-infrared absorption. The influences of Fe3O4 NP concentrations, power density, and wavelength of near-infrared laser irradiation on the photothermal performance of Fe3O4 NPs were investigated. The results revealed that high concentrations, large power density, and short irradiation wavelength could improve the photothermal performance of Fe3O4 NPs. The temperature variation and the absorption intensity simultaneously determined the photothermal transduction efficiency of Fe3O4 NPs. The application of the photothermal performance of Fe3O4 NPs would provide a new opportunity for clinic cancer treatment.

Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles

Biomaterials ◽  
2013 ◽  
Vol 34 (16) ◽  
pp. 4078-4088 ◽  
Author(s):  
Maoquan Chu ◽  
Yuxiang Shao ◽  
Jinliang Peng ◽  
Xiangyun Dai ◽  
Haikuo Li ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Laser Light ◽  
Infrared Laser ◽  
Photothermal Effect ◽  
Fe3o4 Magnetic Nanoparticles

Highly efficient thermogenesis from Fe3O4 nanoparticles for thermoplastic material repair both in air and underwater

2017 ◽  
Vol 5 (3) ◽  
pp. 1221-1232 ◽  
Author(s):  
Xiangyu Yin ◽  
Yue Zhang ◽  
Peng Lin ◽  
Yupeng Liu ◽  
Zuankai Wang ◽  
...  
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Photothermal Effect ◽  
Thermoplastic Material ◽  
Highly Efficient ◽  
Fe3o4 Nps ◽  
The Matrix

A robust photothermal healing method relies on the NIR photothermal effect of Fe3O4 NPs in the matrix. It allows thermoplastic materials and coatings to be repaired in air, and the coatings to be repaired more effectively underwater.

scholarly journals Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yoochan Hong ◽  
Eugene Lee ◽  
Jihye Choi ◽  
Seung Jae Oh ◽  
Seungjoo Haam ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Laser Power ◽  
Near Infrared ◽  
Gold Nanorod ◽  
Photothermal Effect ◽  
Transduction Efficiency ◽  
Dead Cell ◽  
Photothermal Ablation ◽  
Power Densities ◽  
Nir Laser

We estimated the photothermal transduction efficiency of gold nanorod (GNR) solutions for different GNR concentrations and irradiation laser power. In particular, we verified that the degree of cell death area could be modulated by GNR concentration and irradiation laser power. The efficacy of GNR-produced photothermal ablation of cancer cells was evaluated by irradiating GNRs in the presence of MDA-MB-231 breast cancer cells with a near-infrared (NIR) laser at different laser power densities and irradiation times. GNR-induced photothermal ablation was applied successfully to cancer cells at various NIR laser power densities and irradiation times and was characterized with live-dead cell staining. Through these techniques, we established the system for not only verification of induced photothermal effect using NIR laser and thermocouple, but also identification of uptake efficiency for GNRs and cell viability using dark field and fluorescence imaging, respectively.

Photothermal effects and toxicity of Fe3O4 nanoparticles via near infrared laser irradiation for cancer therapy

2015 ◽  
Vol 46 ◽  
pp. 97-102 ◽  
Author(s):  
Andrew W. Dunn ◽  
Sadat M. Ehsan ◽  
David Mast ◽  
Giovanni M. Pauletti ◽  
Hong Xu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Laser Irradiation ◽  
Fe3o4 Nanoparticles ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation ◽  
Photothermal Effects

scholarly journals An Internal Cross-Linked Polymeric Nanoparticle with Dual Sensitivity for Combination Therapy of Muscle-Invasive Bladder Cancer

2020 ◽  
Author(s):  
Guanchen Zhu ◽  
Kaikai Wang ◽  
Haixiang Qin ◽  
Xiaozhi Zhao ◽  
Wei Chen ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Laser Irradiation ◽  
Tumor Cells ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Infrared Laser ◽  
Photothermal Effect ◽  
Bladder Cancer Cells ◽  
Infrared Laser Irradiation

Abstract Chemotherapy is an emerging effective treatment for cancer. However, one of the reasons why chemotherapy has a limited therapeutic effect in bladder cancer is that higher levels of glutathione in invasive bladder cancer cells. We have fabricated nanoparticles that sensitive to high concentrations of glutathione and near-infrared laser irradiation, which increases the drug accumulation at the tumor site and combines chemotherapy with photothermal therapy to overcome the challenges of bladder cancer treatment.Methods: The DOX&IR780@PEG-PCL-SS NPs were prepared by co-precipitation method. We investigated the tumor targeting of NPs in vitro and in vivo. The orthotopic bladder cancer model in C57BL/6 mice was established for in vivo study and photothermal effect of NPs were demonstrated. Therapeutic efficacy of NPs for bladder cancer was evaluated.Results: The DOX&IR780@PEG-PCL-SS NPs we synthesized use internal cross-linking strategy to increase the stability of nanoparticles. Nanoparticles can be ingested by tumor cells in a short time. The DOX&IR780@PEG-PCL-SS NPs have dual sensitivity to high levels of glutathione in bladder cancer cells and near-infrared laser irradiation. Glutathione triggers chemical structural changes in nanoparticles and preliminarily releases drugs, Near-infrared laser irradiation can promote the complete release of the drug from the nanoparticles, producing a photothermal effect and further killing the tumor cells. Given the excellent tumor-targeting ability and negligible toxicity, DOX&IR780@PEG-PCL-SS NPs can greatly increase the concentration of drugs in tumor cells. The mice in the experimental group can be found to have a significant reduction in tumor volume. The DOX&IR780@PEG-PCL-SS NPs can be tracked by small animal imaging and have good imaging results, to facilitate our assessment during the experiment.Conclusion: A dual sensitivity to glutathione and near-infrared laser irradiation. Long-circulating nanoparticle was developed for delivering IR780 and DOX, which could achieve NIR laser-controlled drug release and imaging guidance for chemo-photothermal synergistic therapy of both primary bladder cancer and their metastases.

Photobiostimulation effect on diabetic wound at different power density of near infrared laser

2015 ◽  
Vol 151 ◽  
pp. 201-207 ◽  
Author(s):  
PikSuan Lau ◽  
Noriah Bidin ◽  
Ganesan Krishnan ◽  
Sana Mohammed AnaybBaleg ◽  
Mohamad Bin Md Sum ◽  
...  
Keyword(s):  
Power Density ◽  
Near Infrared ◽  
Infrared Laser ◽  
Diabetic Wound

Study on the Near-infrared Absorption Properties of ZnGeP2 Single Crystals

2010 ◽  
Vol 25 (10) ◽  
pp. 1029-1033
Author(s):  
Shi-Xing XIA ◽  
Chun-Hui YANG ◽  
Chong-Qiang ZHU ◽  
Tian-Hui MA ◽  
Meng WANG ◽  
...  
Keyword(s):  
Single Crystals ◽  
Infrared Absorption ◽  
Near Infrared ◽  
Absorption Properties
Sign in / Sign up

Export Citation Format

Share Document