scholarly journals Myeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Sunmi Jo ◽  
Hye-kyung Shim ◽  
Joo Yeon Kim ◽  
Sang Kyun Bae ◽  
Mi Ra Kim
Keyword(s):  
Salivary Gland ◽  
Literature Review ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Diagnostic Methods ◽  
Myeloid Sarcoma ◽  
Histopathologic Evaluation ◽  
High Index Of Suspicion ◽  
Sebaceous Lymphadenoma

Myeloid sarcoma (MS) is a rarely encountered extramedullary localized tumor that is composed of immature myeloid cells. We reported an extremely rare case of MS with concurrent bone marrow (BM) involvement that invaded into a preexisting sebaceous lymphadenoma in the parotid gland and neck lymph nodes. Prompted by this case, we also present a literature review of MS invasion into salivary glands. A 62-year-old man was initially diagnosed with carcinoma that arose in a sebaceous lymphadenoma in the parotid gland, through a total parotidectomy with neck dissection. After an extensive histopathological review that included immunohistochemistry, a pathologic diagnosis of MS with infiltration into the sebaceous lymphadenoma with concurrent BM involvement was confirmed. MS is difficult to diagnose accurately; herein, we analyzed the clinical presentations and effectiveness of the various diagnostic methods with a review of the literature. There are 17 cases, including our case, reported in 13 studies. Of the cases in which the salivary glands were affected, 10 involved the parotid gland, six involved the submandibular gland, and one involved both. Isolated invasion of the salivary gland was found in one case of parotid gland invasion and three cases of submandibular gland invasion. In 13 cases, the salivary glands were affected by various other lesions. Although there were no incidences of isolated MS, six patients were diagnosed with secondary MS and eight patients with MS with BM involvement, including this case. The diagnosis of MS is difficult given its rarity, and a high index of suspicion and integrated radiologic and careful histopathologic evaluation are required. Most cases of MS infiltrating the salivary gland might be indicated by the possibility of BM involvement. MS with BM involvement predicts poor prognosis and the need for intensive systemic treatment.

Two malignant salivary gland tumours of different type in one patient

1994 ◽  
Vol 108 (9) ◽  
pp. 798-800 ◽  
Author(s):  
A. Hosni ◽  
C. Fisher ◽  
P. Rhŷ-Evans
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Histological Type ◽  
Salivary Gland Tumours ◽  
Adenoid Cystic ◽  
The Right ◽  
Left Parotid Gland

AbstractThe synchronous or metachronous occurrence of two tumours of the salivary glands in one patient is rare. These are mainly benign and of the same histological type. Here we report a 56-year-old man who developed a mucoepidermoid tumour of the left parotid gland four years after diagnosis of adenoid cystic carcinoma of the right submandibular gland. This combination of neoplasms has not to our knowledge been reported before.

Terminal duct adenocarcinomas of the parotid gland

1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Minor Salivary Gland ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Biological Behaviour ◽  
Parotid Neoplasms ◽  
Clinicopathological Study

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.

scholarly journals Salivary gland tumours - a three years experience at King Edward Medical College, Lahore

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Asmaa Qureshi ◽  
Khalilur Rehman ◽  
Sohail Husain ◽  
Nasirul Hasan Khawaja ◽  
Ghulam Rasood Qureshi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Salivary Gland Tumours ◽  
Medical College ◽  
Common Location ◽  
Female Predominance

Salivary gland tumours make an important part of oral & maxillofacial pathology. Only few studies have been done in Pakistani population. The aim of this study was to describe morphological types of salivary gland tumours diagnosed at King Edward Medical College/ Mayo Hospital, Lahore during the years 1999-2001 and to compare their demographic data with those previously published. Material & Methods: This descriptive cross-sectional study was carried out at King Edward Medical College/ Mayo Hospital, Lahore. It reports 117 cases of salivary gland tumours diagnosed at Pathology Department during 1999-2001. Results: Of the 128 specimens of salivary glands, 117(91.4%) were confirmed as salivary neoplasms. Out of them, 62.7% were benign and 37.6% malignant and a slight female predominance (58.1%) was found. The most common location was the parotid gland (65.8%) followed by minor salivary glands (19.6%). Majority oft he t tumours was diagnosed during 3rd to 5 decades of life. Median age for benign tumours was 33 years (range 1-78) and a female predominance (58.9%) was seen again. Median age for malignant neoplasms was 45 years (range 9-70) with a female predilection ( 56.8%). However, 4 out o f 5 patients with Warthin`s tumour were men. Pleomorphic adenoma was the most frequent tumour (51.3%), followed by mucoepidermoid carcinoma (25.6%), adenoid cystic carcinoma (7.7)), Warthin`s tumour (4.3%) and monomorphic adenoma (2.6%). Two cases each of oncytoma & adenocarcinoma were recorded. Rare categories (single case each) of salivary tumours included lipoma, acinic cell carcinoma, basal cell adenoma, capillary haemangioma, metastatic carcinoma and non Hodgkin`s lymphoma. Conclusion: The principal site of salivary tumours was the parotid gland and females were most affected. Pleomorphic adenoma was the most frequent finding. The results of this study are comparable with other studies.

Salivary gland diseases

2018 ◽  
Author(s):  
Max Robinson ◽  
Keith Hunter ◽  
Michael Pemberton ◽  
Philip Sloan
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Neck Region ◽  
Normal Function ◽  
Minor Salivary Glands ◽  
Flow Rates ◽  
Endocrine Disturbances ◽  
Systemic Factors ◽  
Gland Function

The salivary glands consist of three paired major glands—parotid, sub­mandibular, and sublingual—and the countless minor salivary glands found in almost every part of the oral cavity, except the gingiva and anterior regions of the hard palate. The secretion of saliva is essential for the normal function and health of the mouth, and disorders of salivary gland function predispose to oral disease. Functional disorders in salivary secretion may be associated with primary salivary gland disease but in other cases are a consequence of systemic factors, such as medi­cations, endocrine disturbances, and neurological disease, which are discussed in Chapter 10. Developmental anomalies of the salivary glands are rare. Aplasia of one or more major glands and atresia of one or more major salivary gland ducts have been reported. Congenital aplasia of the parotid gland may be associated with other facial abnormalities, e.g. ectodermal dysplasia, mandibulofacial dysostosis, and hemifacial microsomia. Heterotopic salivary tissue has been reported from a variety of sites in the head and neck region, the most frequent being its inclusion at the angle, or within the body, of the mandible, called a Stafne bone cavity. It is usually an incidental radiological finding and appears as a round or oval, well-demarcated radiolucency between the premolar region and angle of the jaw, and is typically located beneath the inferior dental canal. The radiographic appearances are due to a saucer-shaped depression or concavity of varying depth on the lingual aspect of the mandible, which contains salivary tissue in continuity with the submandibular gland. Accessory parotid tissue within the cheek or masseter muscle is rela­tively common and is subject to the same diseases that may affect the main gland. Age changes can be detected in both major and minor salivary glands. Reduction in the weights of submandibular and parotid glands has been reported with increasing age, associated in the submandibular gland with an age-dependent reduction in flow rates. By contrast, sev­eral studies have demonstrated that there is no significant reduction in parotid flow rates in the elderly.

Surgical anatomy of the lymphatic drainage of the salivary glands: a systematic review

2020 ◽  
Vol 134 (10) ◽  
pp. 856-862
Author(s):  
A K Abou-Foul
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Lymph Nodes ◽  
Salivary Glands ◽  
Lymphatic Drainage ◽  
Nodal Metastasis ◽  
Surgical Anatomy ◽  
Complex Anatomy ◽  
Salivary Gland Malignancy ◽  
Metastasis Patterns

AbstractBackgroundNodal metastasis in salivary gland malignancies has important clinical implications; a good understanding of their complex anatomy is paramount to the head and neck surgeon.MethodsA contemporary and comprehensive literature review was conducted of the lymphatic drainage of the salivary glands, with special emphasis on its surgical applications.ResultsThe parotid gland has extraglandular and intraglandular nodes acting as a single functional drainage unit. Intraglandular parotid notes are unique to the parotid gland, and consist of a larger superficial group and a smaller deep group. The presence of intraglandular submandibular nodes, as described by early anatomists, is much debated nowadays. The sublingual glands drain to the lingual lymph nodes, which are divided into median, intermediate and lateral groups.ConclusionThis review highlights the complex arrangements of lymph nodes draining the salivary glands. It may provide a valid anatomical explanation for the nodal metastasis patterns commonly seen in salivary gland malignancy.

scholarly journals Unusually Large Submandibular Sialoliths: Report of Two Cases

2009 ◽  
Vol 03 (02) ◽  
pp. 135-139 ◽  
Author(s):  
Meryem Toraman Alkurt ◽  
Ilkay Peker
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Histopathological Examination ◽  
Floor Of The Mouth ◽  
Common Diseases ◽  
Wharton’S Duct

ABSTRACTSialoliths are the most common diseases of the salivary glands. They may occur in any of the salivary gland ducts but are most common in Wharton’s duct and the submandibular gland. This report presents clinical and radiographical signs of two unusually large sialoliths. There were painless swellings on the floor of the mouth in both cases. Radiographical examination revealed large irregular radioopaque mass superimposed right canine and premolar areas. After the lesions were removed, histopathological examination was performed and lesions were diagnosed as sialoliths. (Eur J Dent 2009;3:135-139)

scholarly journals Diagnostic Accuracy of Fine-Needle Biopsy for Salivary Gland Neoplasms in a Community Otolaryngology Practice

OTO Open ◽  
2020 ◽  
Vol 4 (3) ◽  
pp. 2473974X2094918
Author(s):  
Jennifer L. Harb ◽  
Dara Bakar ◽  
Jagdish K. Dhingra
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Diagnostic Accuracy ◽  
Submandibular Gland ◽  
Sensitivity And Specificity ◽  
Needle Biopsy ◽  
Fine Needle Biopsy ◽  
Salivary Gland Neoplasms ◽  
Community Practice ◽  
Fine Needle

Objective To assess the diagnostic accuracy of fine-needle biopsy (FNB) of salivary gland neoplasms via ultrasound (US) or palpation guidance by an otolaryngologist in a community practice. Study Design Retrospective chart review. Setting Community otolaryngology practice. Methods Retrospective analysis was conducted for all office-based salivary gland FNBs from a community practice from 2005 through 2018. There were 433 FNBs performed among 370 patients. The likelihood of achieving a diagnostic result based on method (US vs palpation guidance) was calculated. Of this cohort, 196 cases had surgical follow-up (parotid gland, n = 168; submandibular gland, n = 28). Correlation of preoperative FNB results to final surgical pathology was performed and measures of diagnostic accuracy computed. Results US-guided FNBs were more likely to achieve a diagnostic result than FNBs obtained via palpation guidance ( P = .00002). Parotid gland FNBs demonstrated a sensitivity and specificity of 78.57% and 92.44%, respectively. Submandibular FNBs demonstrated a sensitivity and specificity of 57.14% and 93.74%. Conclusion FNBs performed under US guidance are more likely to achieve a diagnostic specimen than those performed under palpation guidance. FNBs of parotid gland tumors may be assessed with diagnostic accuracy in the community setting that is similar to that achieved at tertiary care centers. Further research is needed to ascertain whether this finding extends to FNBs of submandibular gland tumors. Offering this procedure at point of care in the community may improve compliance and reduce wait time.

Electromyography Monitoring of Patients With Salivary Gland Diseases

2005 ◽  
Vol 133 (6) ◽  
pp. 869-873 ◽  
Author(s):  
Michael Vaiman ◽  
Oded Nahlieli ◽  
Samuel Segal ◽  
Ephraim Eviatar
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Healthy Volunteers ◽  
Submandibular Gland ◽  
Study Design ◽  
Flow Rate ◽  
Surface Electromyography ◽  
Salivary Flow ◽  
Reliable Data ◽  
Salivary Gland Diseases

OBJECTIVE: To provide a description of surface electromyography (sEMG) of spontaneous saliva swallowing (SSS) and monitoring of swallow rate in patients with salivary gland diseases. STUDY DESIGN: Numbers of SSS obtained during 2 hours of sEMG monitoring were compared with sialometry data for healthy volunteers (n = 100), patients with Sjögren syndrome (n = 10), and patients after parotid gland (n = 15) and submandibular gland (n = 16) surgery. RESULTS: Normative: 1 SSS every 2 minutes and 15 seconds; Sjögren: 1 SSS every 13 minutes ( P < 0.001); parotid gland surgery: 1 SSS every 3 minutes and 24 seconds ( P = 0.26); submandibular gland surgery: 1 SSS every 5 minutes and 04 seconds ( P < 0.05). Sjögren patients and patients after submandibular surgery had hyposalivation correlated with less SSS. CONCLUSION: The established normal rate of SSS makes this modality applicable for evaluating salivary flow for potentially identifying and ruling out abnormalities. Parotid gland surgery does not significantly affect salivary flow rate. Sialometry combined with sEMG monitoring give a clinician more reliable data to evaluate salivary gland disorders than sialometry alone. EBM RATING: B-2

Sign in / Sign up

Export Citation Format

Share Document