scholarly journals Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior

2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Wei Zhou ◽  
Yugen Yi ◽  
Yuan Gao ◽  
Jiangyan Dai

Accurate optic disc and optic cup segmentation plays an important role for diagnosing glaucoma. However, most existing segmentation approaches suffer from the following limitations. On the one hand, image devices or illumination variations always lead to intensity inhomogeneity in the fundus image. On the other hand, the spatial prior knowledge of optic disc and optic cup, e.g., the optic cup is always contained inside the optic disc region, is ignored. Therefore, the effectiveness of segmentation approaches is greatly reduced. Different from most previous approaches, we present a novel locally statistical active contour model with the structure prior (LSACM-SP) approach to jointly and robustly segment the optic disc and optic cup structures. First, some preprocessing techniques are used to automatically extract initial contour of object. Then, we introduce the locally statistical active contour model (LSACM) to optic disc and optic cup segmentation in the presence of intensity inhomogeneity. Finally, taking the specific morphology of optic disc and optic cup into consideration, a novel structure prior is proposed to guide the model to generate accurate segmentation results. Experimental results demonstrate the advantage and superiority of our approach on two publicly available databases, i.e., DRISHTI-GS and RIM-ONE r2, by comparing with some well-known algorithms.

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Ming Gu ◽  
Renfang Wang

A novel active contour model is proposed for segmentation images with inhomogeneity. Firstly, fractional order filter is defined by eight convolution masks corresponding to the image orientation in the eight compass directions. Then, the fractional order differentiation image is obtained and applied to the level set method. Secondly, we defined a new energy functional based on local image information and fractional order differentiation image; the proposed model not only can describe the input image more accurately but also can deal with intensity inhomogeneity. Local fitting term can enhance the ability of the model to deal with intensity inhomogeneity. The defined penalty term is used to reduce the occurrence of false boundaries. Finally, in order to eliminate the time-consuming step of reinitialization and ensure stable evolution of level set function, the Gaussian filtering method is used. Experiments on synthetic and real images show that the proposed model is efficient for images with intensity inhomogeneity and flexible to initial contour.


2021 ◽  
pp. 1-19
Author(s):  
Maria Tamoor ◽  
Irfan Younas

Medical image segmentation is a key step to assist diagnosis of several diseases, and accuracy of a segmentation method is important for further treatments of different diseases. Different medical imaging modalities have different challenges such as intensity inhomogeneity, noise, low contrast, and ill-defined boundaries, which make automated segmentation a difficult task. To handle these issues, we propose a new fully automated method for medical image segmentation, which utilizes the advantages of thresholding and an active contour model. In this study, a Harris Hawks optimizer is applied to determine the optimal thresholding value, which is used to obtain the initial contour for segmentation. The obtained contour is further refined by using a spatially varying Gaussian kernel in the active contour model. The proposed method is then validated using a standard skin dataset (ISBI 2016), which consists of variable-sized lesions and different challenging artifacts, and a standard cardiac magnetic resonance dataset (ACDC, MICCAI 2017) with a wide spectrum of normal hearts, congenital heart diseases, and cardiac dysfunction. Experimental results show that the proposed method can effectively segment the region of interest and produce superior segmentation results for skin (overall Dice Score 0.90) and cardiac dataset (overall Dice Score 0.93), as compared to other state-of-the-art algorithms.


2014 ◽  
Vol 513-517 ◽  
pp. 3463-3467
Author(s):  
Li Fen Zhou ◽  
Chang Xu Cai

The Chan-Vese (C-V) active contour model has low computational complexity, initialization and insensitive to noise advantagesand utilizes global region information of images, so it is difficult to handle images with intensity inhomogeneity. The Local binary fitting (LBF) model based on local region information has its certain advantages in mages segmentation of weak boundary or uneven greay.but , the segmentation results are very sensitive to the initial contours, In order to address this problem, this paper proposes a new active contour model with a partial differential equation, which integrates both global and local region information. Experimental results show that it has a distinctive advantage over C-V model for images with intensity inhomogeneity, and it is more efficient than LBF.


IEEE Access ◽  
2018 ◽  
Vol 6 ◽  
pp. 54224-54240 ◽  
Author(s):  
Qing Cai ◽  
Huiying Liu ◽  
Yiming Qian ◽  
Jing Li ◽  
Xiaojun Duan ◽  
...  

Author(s):  
Mouri Hayat ◽  
Fizazi Hadria

<p>Global and local image information is crucial for accurate segmentation of images with intensity inhomogeneity valuable minute details and multiple objects with various intensities. We propose a region-based active contour model which is able to utilize together local and global image information. The major contribution of this paper is to expand the LIF model which is includes only local image infofmation to a local and global model. The introduction of a new local and global signed pressure force function enables the extraction of accurate local and global image information and extracts multiple objects with several intensities. Several tests performed on some synthetic and real images indicate that our model is effective as well as less sensitivity to the initial contour location and less time compared with the related works. </p><p><em> </em></p>


Author(s):  
Shigang Liu ◽  
Yali Peng ◽  
Guoyong Qiu ◽  
Xuanwen Hao

This paper presents a local statistical information (LSI) active contour model. Assuming that the distribution of intensity belonging to each region is a Gaussian distribution with spatially varying statistical information, and defining an energy function, the authors integrate the entire image domain. Then, this energy is incorporated into a variational level set formulation. Finally, by minimizing the energy functional, a curve evolution equation can be obtained. Because the image local information is considered, the proposed model can effectively deal with the image with intensity inhomogeneity. Experimental results on synthetic and real images demonstrate that the proposed model can effectively segment the image with intensity inhomogeneity.


Author(s):  
Guimei Zhang ◽  
Yangang Zhu ◽  
Jianxin Liu ◽  
YangQuan Chen

Intensity inhomogeneity or weak texture region image segmentation plays an important role in computer vision and image processing. RSF (Region-Scalable Fitting) active contour model has been proved to be an effective method to segment intensity inhomogeneity. However RSF model is sensitive to the initial location of evolution curve , it tends to fall into local optimal. Aiming at the problem, this paper proposed a new method for image segmentation based on fractional differentiation and RSF model. The proposed method adds the global Grünwald-Letnikov fractional gradient into the RSF model. Thus the gradient of the intensity inhomogeneity and weak texture regions is strengthened. As a result, both the robustness of initial location of evolution curve and efficiency of image segmentation are improved. Theoretical analysis and experimental results demonstrate that the proposed algorithm is capable of segmenting the intensity inhomogeneities and weak texture images. It is robust to curve initial location, furthermore the efficiency of segmentation is improved.


2015 ◽  
Vol 15 (03) ◽  
pp. 1550010
Author(s):  
Hao Liu ◽  
Hongbo Qian ◽  
Ning Dai ◽  
Jianning Zhao

It is an important segmentation approach of CT/MRI images to automatically extract contours in every slice using active contour models. The key point of the segmentation approach is to automatically construct initial contours for active contour models because any active contour model is sensitive to its initial contour. This paper presents an algorithm to construct such initial contours using a heuristic method. Assume that the contour in previous slice (previous contour) is accurate. The contour in the current slice (current contour) is constructed according to the previous contour using the way: Recognition and link of edge points of tissues according to the previous contour. The contour linking edge points is used as the initial contour of the distance regularized level set evolution (DRLSE) method and then an accurate contour can be extracted in the current slice.


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