scholarly journals Tensile Properties of Three Selected Collagen Membranes

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Perry Raz ◽  
Tamar Brosh ◽  
Guy Ronen ◽  
Haim Tal
Keyword(s):  
Mechanical Properties ◽  
Alveolar Bone ◽  
Tensile Force ◽  
Maximum Load ◽  
Collagen Membrane ◽  
Mechanical Resistance ◽  
Standard Size ◽  
Maximum Extension ◽  
Collagen Membranes ◽  
Membrane Density

Background. Biological barriers are commonly used to treat alveolar bone defects and guide tissue regeneration. Understanding the biological and mechanical properties of the available membranes is crucial for selecting the one that is optimal for enhancing clinical outcomes. Purpose. To evaluate the mechanical behavior of three different collagen membranes to increasing tensile force in dry and wet conditions. Materials and Methods. Three commercially collagen membranes were selected for analysis: Bio-Gide® (Geistlich Biomaterials, Baden-Baden, Germany), Remaix™ (RX; Matricel GmbH, Herzogenrath, Germany), and Ossix Plus® (Datum Dental Biotech, Lod, Israel). Increasing tensile forces were applied on 10 dry and wet membranes of standard size via a loading machine. Force and extension values were acquired up to maximum load before failure, and maximum stress, maximum extension, and amount of energy needed for membrane tearing were analyzed. Membranes’ densities were also calculated. Results. The Remaix membrane exhibited the highest values of maximum load tensile strength, maximum extension, and maximum energy required for membrane tearing, followed by Bio-Gide. Ossix Plus had the lowest scores in all these parameters. Dry membranes had the highest scores for all parameters except extension. Membrane density was directly and significantly correlated with all tested parameters. Conclusions. The study was undertaken to provide clinicians with data upon which to base the selection of collagen membranes in order to achieve optimal clinical results. It emerged that the mechanical properties of dry and wet collagen membranes were significantly different from one another. Among the 3 tested membranes, Remaix exhibited higher performance results in all the mechanical tests. Collagen membrane density seems to have a significant influence upon mechanical resistance. These findings may also guide manufacturers in improving the quality of their product.

scholarly journals The effect of acellular dermal matrix therapy on biphasic calsium sulfate bone graft

2020 ◽  
Vol 6 (1) ◽  
pp. 48
Author(s):  
Angga Febriharta ◽  
Kwartarini Murdiastuti
Keyword(s):  
Disease Transmission ◽  
Alveolar Bone ◽  
Acellular Dermal Matrix ◽  
Gingival Recession ◽  
Collagen Membrane ◽  
Dermal Matrix ◽  
Attachment Loss ◽  
Collagen Membranes ◽  
Acellular Dermal ◽  
Bone Height

Infrabony pocket therapy is needed to eliminate pocket wall, creating easy to clean conditions for new attachment, and bone regeneration. Biphasic calcium sulfate (BCS) bone grafts combined with collagen membranes are known to regenerate bone tissue and have good osteoconductive effects. The addition of collagen membranes promotes migration and proliferation of fibroblast cells, osteoblasts, and homeostasis. However, the collagen membrane is a rapidbioresynthesis and may cause disease transmission from animal. Acellular dermal matrix (ADMA) membrane contains a bioactive matrix that has the ability to support normal revascularization, cell repopulation, and tissue remodeling. Combination of BCS with ADMA membrane are proven to induce bone and tissue regeneration. The objective of this study is to determine the therapeutic effect of BSC and ADMA combination to eradicate pocket, gingival recession, bone recession and attachment loss. The samples were taken from 20 infrabony pocket sites divided into 2 groups. The first was treated by combination of BCS and ADMA, while the second group was treated by the combination of BCS and collagen membrane. After 1 and 3 months of flap surgery, the result was observed by probing depth(PD), relative attachment loss (RAL), gingival recession, alveolar bone height and radiological examination. The result showed the decrease of PD, RAL, gingival recession, and alveolar bone height in both two groups. However, there wereno significant differences between those two groups. In conclusion, the combination of BCS and ADMA or BCS and collagen decreased the PD, RAL, gingival recession and alveolar bone height.

Structural features and strength behavior of TRIP/TWIP steels

2020 ◽  
pp. 5-18
Author(s):  
D. V. Prosvirnin ◽  
◽  
M. S. Larionov ◽  
S. V. Pivovarchik ◽  
A. G. Kolmakov ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Chemical Composition ◽  
Thermomechanical Processing ◽  
Maximum Load ◽  
Structural Features ◽  
Stacking Fault ◽  
Stacking Fault Energy ◽  
Structural And Functional Properties ◽  
Twip Steels ◽  
The Creation

A review of the literature data on the structural features of TRIP / TWIP steels, their relationship with mechanical properties and the relationship of strength parameters under static and cyclic loading was carried out. It is shown that the level of mechanical properties of such steels is determined by the chemical composition and processing technology (thermal and thermomechanical processing, hot and cold pressure treatment), aimed at achieving a favorable phase composition. At the atomic level, the most important factor is stacking fault energy, the level of which will be decisive in the formation of austenite twins and / or the formation of strain martensite. By selecting the chemical composition, it is possible to set the stacking fault energy corresponding to the necessary mechanical characteristics. In the case of cyclic loads, an important role is played by the strain rate and the maximum load during testing. So at high loading rates and a load approaching the yield strength under tension, the intensity of the twinning processes and the formation of martensite increases. It is shown that one of the relevant ways to further increase of the structural and functional properties of TRIP and TWIP steels is the creation of composite materials on their basis. At present, surface modification and coating, especially by ion-vacuum methods, can be considered the most promising direction for the creation of such composites.

scholarly journals Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jila Nasirzade ◽  
Zahra Kargarpour ◽  
Goran Mitulović ◽  
Franz Josef Strauss ◽  
Layla Panahipour ◽  
...  
Keyword(s):  
Cellular Response ◽  
Alveolar Bone ◽  
Quantitative Polymerase Chain Reaction ◽  
Genomic Analysis ◽  
Type I ◽  
Gingival Fibroblasts ◽  
Nadph Oxidase 4 ◽  
Major Response ◽  
Collagen Membranes ◽  
Β Receptor

AbstractParticulate autologous tooth roots are increasingly used for alveolar bone augmentation; however, the proteomic profile of acid dentin lysate and the respective cellular response have not been investigated. Here we show that TGF-β1 is among the 226 proteins of acid dentin lysate (ADL) prepared from porcine teeth. RNA sequencing identified 231 strongly regulated genes when gingival fibroblasts were exposed to ADL. Out of these genes, about one third required activation of the TGF-β receptor type I kinase including interleukin 11 (IL11) and NADPH oxidase 4 (NOX4). Reverse transcription-quantitative polymerase chain reaction and immunoassay confirmed the TGF-β-dependent expression of IL11 and NOX4. The activation of canonical TGF-β signaling by ADL was further confirmed by the phosphorylation of Smad3 and translocation of Smad2/3, using Western blot and immunofluorescence staining, respectively. Finally, we showed that TGF-β activity released from dentin by acid lysis adsorbs to titanium and collagen membranes. These findings suggest that dentin particles are a rich source of TGF-β causing a major response of gingival fibroblasts.

scholarly journals Diffuse approximation for identification of the mechanical properties of microcapsules

2020 ◽  
pp. 108128652097760
Author(s):  
Carlos Quesada ◽  
Claire Dupont ◽  
Pierre Villon ◽  
Anne-Virginie Salsac
Keyword(s):  
Mechanical Properties ◽  
Active Material ◽  
Liquid Core ◽  
Constitutive Law ◽  
Data Driven ◽  
Membrane Properties ◽  
Mechanical Resistance ◽  
Data Set ◽  
Diffuse Approximation ◽  
Capsule Size

A novel data-driven real-time procedure based on diffuse approximation is proposed to characterize the mechanical behavior of liquid-core microcapsules from their deformed shape and identify the mechanical properties of the submicron-thick membrane that protects the inner core through inverse analysis. The method first involves experimentally acquiring the deformed shape that a given microcapsule takes at steady state when it flows through a microfluidic microchannel of comparable cross-sectional size. From the mid-plane capsule profile, we deduce two characteristic geometric quantities that uniquely characterize the shape taken by the microcapsule under external hydrodynamic stresses. To identify the values of the unknown rigidity of the membrane and of the size of the capsule, we compare the geometric quantities with the values predicted numerically using a fluid-structure-interaction model by solving the three-dimensional capsule-flow interactions. The complete numerical data set is obtained off-line by systematically varying the governing parameters of the problem, i.e. the capsule-to-tube confinement ratio, and the capillary number, which is the ratio of the viscous to elastic forces. We show that diffuse approximation efficiently estimates the unknown mechanical resistance of the capsule membrane. We validate the data-driven procedure by applying it to the geometric and mechanical characterization of ovalbumin microcapsules (diameter of the order of a few tens of microns). As soon as the capsule is sufficiently deformed to exhibit a parachute shape at the rear, the capsule size and surface shear modulus are determined with an accuracy of 0.2% and 2.7%, respectively, as compared with 2–3% and 25% without it, in the best cases (Hu et al. Characterizing the membrane properties of capsules flowing in a square-section microfluidic channel: Effects of the membrane constitutive law. Phys Rev E 2013; 87(6): 063008). Diffuse approximation thus allows the capsule size and membrane elastic resistance to be provided quasi-instantly with very high precision. This opens interesting perspectives for industrial applications that require tight control of the capsule mechanical properties in order to secure their behavior when they transport active material.

Study on the Mechanical Properties and Handle of PTT/Wool Blended Fabrics

2010 ◽  
Vol 150-151 ◽  
pp. 1810-1813
Author(s):  
Guang Biao Xu ◽  
Lian Ying Zhao ◽  
Fu Mei Wang
Keyword(s):  
Mechanical Properties ◽  
Friction Coefficient ◽  
Surface Friction ◽  
Maximum Load ◽  
Wool Fabrics

The low-stress properties of PTT/wool blended fabrics were investigated by comparing with PET/wool blended fabrics. The results show that, the elongation of PTT/wool fabrics at the maximum load is higher, especially in filling wise, which means PTT/wool fabrics have better elastic. The bending hysteresis, shearing rigidity and shearing hysteresis of PTT/wool fabrics are higher than those of PET/wool fabrics, determining the fabrics having good formability. PTT/wool fabrics are easier to be compressed, and has a little higher surface friction coefficient, giving the fabrics better feeling of softness and fullness. The hand values show that PTT/wool blended fabrics are softer, and have the good bulkiness but not as good as that of PET/wool fabrics.

In Vitro and In Vivo Degradation, Mechanical Properties, and Histocompatibility of Weft-Knitted Silk Mesh-Like Grafts

2022 ◽  
Vol 12 (2) ◽  
pp. 411-416
Author(s):  
Liang Tang ◽  
Si-Yu Zhao ◽  
Ya-Dong Yang ◽  
Geng Yang ◽  
Wen-Yuan Zhang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Degradation Rate ◽  
Maximum Load ◽  
Artificial Ligament ◽  
In Vivo Degradation

To investigate the degradation, mechanical properties, and histocompatibility of weft-knitted silk mesh-like grafts, we carried out the In Vitro and In Vivo silk grafts degradation assay. The In Vitro degradation experiment was performed by immersing the silk grafts in simulated body fluid for 1 year, and the results showed that the degradation rate of the silk mesh-like grafts was very slow, and there were few changes in the mechanical properties and quality of the silk mesh-like graft. In Vivo degradation assay was taken by implantation of the silk mesh-like grafts into the subcutaneous muscles of rabbits. At 3, 6, and 12 months postoperation, the rate of mass loss was 19.36%, 31.84%, and 58.77%, respectively, and the maximum load was 63.85%, 34.63%, and 10.76%, respectively of that prior to degradation. The results showed that the degradation rate of the silk graft and the loss of mechanical properties In Vivo were faster than the results obtained in the In Vitro experiments. In addition, there were no significant differences in secretion of serum IL-6 and TNF-α between the experimental and normal rabbits (P >0.05), suggesting no obvious inflammatory reaction. The findings suggest that the weft-knitted silk mesh-like grafts have good mechanical properties, histocompatibility, and In Vivo degradation rate, and therefore represent a candidate material for artificial ligament

scholarly journals Postoperative Pericardial Adhesion Prevention Using Collagen Membrane in Pigs: A Pilot Study

2017 ◽  
Vol 9 ◽  
pp. 117906521772090 ◽  
Author(s):  
Noppon Taksaudom ◽  
Metus Ketwong ◽  
Nirush Lertprasertsuke ◽  
Aphisek Kongkaew
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
The Body ◽  
Adhesion Prevention ◽  
Control Group ◽  
Collagen Membrane ◽  
Pericardial Cavity ◽  
True Value ◽  
Collagen Membranes ◽  
Experimental Group

Objective: The operating procedure of a resternotomy in open-heart surgery is a complicated procedure with potentially problematic outcomes partly due to potential adhesions in the pericardial cavity and retrosternal space. Use of a collagen membrane has shown encouraging results in adhesion prevention in several regions of the body. This study was designed to evaluate the effectiveness of the use of this collagen membrane in the prevention of pericardial adhesions. Materials and methods: A total of 12 pigs were divided randomly into 2 groups: an experimental group in which collagen membranes were used and a control group. After sternotomy and an anterior pericardiectomy, the epicardial surface was exposed to room air and irrigated with saline, and an epicardial abrasion was performed using a sponge. The pericardial defect was repaired using a collagen membrane in the experimental group or left uncovered in the control group. After 8 to 12 weeks, the pigs were killed, and a resternotomy was performed by a single-blinded surgeon enabling the evaluation of adhesions. The heart was then removed and sent for microscopic assessment conducted by a single-blinded pathologist. Results: The resternotomy operations performed using a collagen membrane demonstrated a nonstatistically significant trend of fewer macroscopic and microscopic adhesions in all regions ( P > .05), particularly in the retrosternal and defect regions. Conclusions: This study showed nonstatistically significant differences between the outcomes in the collagen membrane group and the control group in both macroscopic and microscopic adhesion prevention. Due to the many limitations in animal study design, further studies in human models will be needed before the true value of this procedure can be evaluated.

scholarly journals Automatic Evaluation of the Mechanical Properties of Steels Maraging using Digital Image Processing Techniques

2020 ◽  
Author(s):  
Angélica Alves Viana ◽  
Savio Lopes Rabelo ◽  
José Daniel de Alencar Santos ◽  
Venceslau Xavier de Lima Filho ◽  
Douglas De Araújo Rodrigues ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Fracture Toughness ◽  
Maraging Steel ◽  
Raw Material ◽  
High Fracture Toughness ◽  
Mechanical Resistance ◽  
High Fracture ◽  
Traditional System ◽  
Transformation Methods ◽  
Processing Techniques

Some strategic sectors of the economy require that the raw material of their machines and equipment have mechanical properties that satisfy their use. Maraging steel is a material of great concern since it is necessary to have a high mechanical resistance associated with high fracture toughness. The traditional tests to determine the fracture toughness of this material before use in applications are the Charpy and KIC tests. However, this process is characterized by being exhaustive and requiring specialized and trained professionals. Thus, to reverse this situation, this work proposes a new approach to determine the mechanical properties of maraging steel. For this, initially, the method removes any artifacts present in the image resulting from the mode of acquisition. In sequence, this works tested the method Extended Minimum Transformation (EMT) and mathematical morphology to find these markers of the regions of the dimples. Then, the Adaptive Thresholding, Optimal Global Thresholdusing the Otsu Method and Watershed transformation methods were used to segment the dimples. In the end, the diameter of the dimples and the toughness of the material were calculated. Tests are carried out and compared with the result obtained by specialists using the traditional system to evaluate the proposed approach. The results obtained were satisfactory for the application because the proposed approach presented speed and precision to the conventional methods.

scholarly journals EXPERIMENTAL STUDY OF THE USE OF BIODEGRADABLE COLLAGEN MEMBRANES IN THE CLOSURE OF POSTOPERATIVE DEFECTS OF THE RABBIT ORAL MUCOUS MEMBRANE

2019 ◽  
Vol 23 (5) ◽  
pp. 192-196
Author(s):  
S. V Tarasenko ◽  
A. B Shehter ◽  
E. V Istranova ◽  
E. A Morozova ◽  
Nataliya A. Blagushina
Keyword(s):  
Mucous Membrane ◽  
Wound Repair ◽  
Hard Palate ◽  
Control Group ◽  
Collagen Membrane ◽  
Research Groups ◽  
Dental Patients ◽  
Oral Mucous Membrane ◽  
Secondary Tissue ◽  
Collagen Membranes

The aim is to increase the efficiency of surgical treatment of dental patients with the use of bioresorbable collagen membranes to close postoperative wound defects of the oral mucous membrane. Material and methods. The experimental model was created on 18 laboratory rabbits. The animals were divided into 3 groups: in the control group the healing of the mucous membrane defect on the hard palate was carried out by secondary tissue tension, in the research groups - under the xenopericardium membrane (1) and collagen membrane (2). The morphological study was based on biopsy of all animals' mucous membranes of the hard palate. Microvolume slices 4-5 microns thick were examined on a light microscope. Results. The results testify to the formation of granulation tissue an d epithelization of defects both in the research groups and in the control group. When using collagen materials, a noticeable activatio n of the wound process, shortening of epithelialization were found. A certain advantage of pericardium in activation of wound repair was noted. Conclusion. Application of collagen membranes can be recommended as a method of choice at closing of postoperative defects of the oral mucous membrane after clinical studies.

scholarly journals Effect of nano-solid particles on the mechanical properties of shear thickening fluid (STF) and STF-Kevlar composite fabric

2021 ◽  
Vol 16 ◽  
pp. 155892502110448
Author(s):  
Mingmei Zhao ◽  
Jinqiu Zhang ◽  
Zhizhao Peng ◽  
Jian Zhang
Keyword(s):  
Mechanical Properties ◽  
High Speed ◽  
Split Hopkinson Pressure Bar ◽  
Tensile Force ◽  
Shear Thickening ◽  
Solid Particles ◽  
Time Range ◽  
Shear Thickening Fluid ◽  
Pull Out ◽  
Diamond Particles

To analyze the effect of nano-solid particles on the mechanical properties of shear thickening fluid (STF) and its Kevlar composite fabric. In this study, nano-silica and polyethylene glycol (PEG 200) were used as dispersed and continuous phases. Nano-graphite and nano-diamond particles were used as additives to prepare STF and Kevlar composite fabric. Study the friction characteristics and rheological characteristics of STF at different temperatures. Explore the STF’s mechanical response under transient high-speed impact conditions through the split Hopkinson pressure bar experiment. The mechanical properties of STF-Kevlar fabric are studied through yarn pull-out test and burst experiments. The experimental results show that the intermolecular repulsive force of STF is enhanced under a high-temperature environment, and shear thickening effect is reduced. Nano-diamond particles strengthen the contact coupling force and contact probability between the particle clusters, so that the maximum viscosity of the system reaches 1679 Pa s, the thickening ratio reaches 318 times, and the rheological properties of the shear thickening fluid are improved. The results of the SHPB experiment show that the STF can complete a dynamic response within a 50–75 µs time range, and the maximum stress can reach 78 MPa. The bullet’s incident kinetic energy is not only transformed into thermal energy and phase change energy of solid-liquid conversion, but also into frictional energy between particles. The mechanical experiments of STF-Kevlar composite fabrics show that the tensile force value of STF5-Kevlar is the largest (10.3 N/13.5 N), and the tensile force of neat Kevlar was the smallest (4.3 N/4.9 N). The maximum bearing capacity (0.3 kN) and absorption energy (51.8 J) of Neat Kevlar are less than those of STF1-Kevlar (3.2 kN, 116.7 J) and STF3-Kevlar (1.9 kN, 88.2 J), and STF5-Kevlar (4.7 kN, 143.3 J). Fabric’s failure mode is converted from partial yarn extraction to overall deformation and rupture of the fabric. Therefore, by changing the solid additives’ parameters, the STF and the composite fabric’s mechanical properties can be effectively controlled, which provides a reference for preparing the STF and fabric composite materials.

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