scholarly journals Response to: Comment on “Sex Differences in the Association between Night Shift Work and the Risk of Cancers: A Meta-Analysis of 57 Articles”

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Wen Liu ◽  
Zhonghan Zhou ◽  
Dahai Dong ◽  
Lijiang Sun ◽  
Guiming Zhang
Keyword(s):  
Sex Differences ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Night Shift Work

scholarly journals Sex Differences in the Association between Night Shift Work and the Risk of Cancers: A Meta-Analysis of 57 Articles

2018 ◽  
Vol 2018 ◽  
pp. 1-20 ◽  
Author(s):  
Wen Liu ◽  
Zhonghan Zhou ◽  
Dahai Dong ◽  
Lijiang Sun ◽  
Guiming Zhang
Keyword(s):  
Sex Differences ◽  
Cancer Risk ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Case Control ◽  
Sensitivity Analyses ◽  
Response Analysis ◽  
Night Shift Work ◽  
Risk Of Cancer

Objectives. To identify the association between night shift work and the risk of various cancers with a comprehensive perspective and to explore sex differences in this association. Methods. We searched PubMed, Embase, and Web of Science for studies on the effect of night shift work on cancer, including case-control, cohort, and nested case-control studies. We computed risk estimates with 95% confidence intervals (CIs) in a random or fixed effects model and quantified heterogeneity using the I2 statistic. Subgroup, metaregression, and sensitivity analyses were performed to explore potential sources of heterogeneity. Contour-enhanced funnel plots and the trim and fill method were used together to analyze bias. Linear dose–response analysis was used to quantitatively estimate the accumulative effect of night shift work on the risk of cancer. Results. Fifty-eight studies were eligible for our meta-analysis, including 5,143,838 participants. In the random effects model, the pooled odds ratio (OR) of cancers was 1.15 (95% CI = 1.08–1.22, P<0.001; I2=76.2%). Night shift work increased the cancer risk in both men (OR = 1.14, 95% CI = 1.05–1.25, P=0.003) and women (OR = 1.12, 95% CI = 1.04–1.20, P=0.002). Subgroup analyses showed that night shift work positively increased the risk of breast (OR = 1.22, 95% CI = 1.08–1.38), prostate (OR = 1.26, 95% CI = 1.05–1.52), and digestive system (OR = 1.15, 95% CI = 1.01–1.32) cancers. For every 5 years of night shift work, the cancer risk increased by 3.2% (OR = 1.032, 95% CI = 1.013–1.051). Conclusion. This is the first meta-analysis identifying the positive association between night shift work and the risk of cancer and verifying that there is no sex difference in the effect of night shift work on cancer risk. Cancer risk increases with cumulative years of night shift work.

Association between Night-Shift-Work and Level of Melatonin: Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Tao Wei ◽  
Cancan Li ◽  
Yuanyuan Heng ◽  
Xiang Gao ◽  
Guimei Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Night Shift Work

scholarly journals 0147 Meta-analysis on night shift work and risk of metabolic syndrome

2014 ◽  
Vol 71 (Suppl 1) ◽  
pp. A78.3-A78 ◽  
Author(s):  
Feng Wang ◽  
Liuzhuo Zhang ◽  
Yanfang Zhang ◽  
Bo Zhang ◽  
Yonghua He ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Night Shift Work

Is shift-work associated with increased risk of rectal cancer? A meta-analysis.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e15600-e15600
Author(s):  
Chenyu Sun ◽  
Ce Cheng ◽  
Kelly Kozma ◽  
Gopika Chandra ◽  
Na Hyun Kim ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cancer Risk ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Fixed Effect Model ◽  
Night Shift Work ◽  
Increased Risk ◽  
Rotating Shift Work ◽  
Trim And Fill

e15600 Background: Globally, more than 1.8 million people were diagnosed of colorectal cancer (CRC) in 2018, with over 30% of CRC in the rectum. Shift-work, involving circadian disruption, sleep deprivation and lifestyle changes, was designated as a probable cause of cancer by The International Agency for Research on Cancer. Previous studies investigating the impact of permanent night-shift work and rotating shift-work on rectal cancer risk showed controversial results. Thus, this meta-analysis was conducted. Methods: A comprehensive literature search on PubMed was conducted to identify all relevant studies published prior to January 2021 according to the established inclusion criteria. The quality assessment was performed by the Newcastle-Ottawa Scale (NOS). The pooled odds ratio (OR) and 95% confidence intervals (CI) were calculated to estimate the association between the shift-work and rectal cancer risk. Based on heterogeneity significance, random-effect or fixed-effect model was used. Subgroup analyses were conducted to explore the night-shift and rotating-shift, respectively. Sensitivity analysis and publication bias detection were performed, and trim and fill analysis was also conducted. All statistical analyses were performed using RevMan software (version 5.3; Cochrane library) and STATA 15.0 statistical software (Stata Corp., College Station, TX), and all P values were two-tailed, the test level was 0.05. Results: Thirty-seven articles were obtained from database searching. Three articles involving 1,063 rectal cancer cases were included. All studies were considered moderate to high quality. All included studies investigated on the association between shift-work and rectal cancer risk. A statistically significant association between shift-work and increased rectal cancer risk was found (OR 1.53, 95%CI: 1.31, 1.79, P< 0.00001, I 2 = 35%). In subgroup analyses, night-shift work was associated with a non-statistically significant increased risk of rectal cancer (OR 1.25, 95%CI: 0.47, 3.32, P = 0.66, I 2 = 93%). In contrast, Rotating-shift was associated with a statistically significant increased rectal cancer risk (OR 1.35, 95%CI: 1.10, 1.65, P = 0.004, I 2 = 6%). Sensitivity analysis confirmed the stability of the result. Funnel plot, Egger's test (t = 1.69, P = 0.341), and Begg's test (z = 1.04, P = 0.296) found no publication bias of analysis. Trim and fill analysis on fixed-effect model showed the pooled OR kept stable after adding two “missing” studies (OR 1.403, 95%CI: 1.224, 1.609, P <0.05). Conclusions: The current meta-analysis demonstrates that shift-work is associated with increased rectal cancer risk. However, no association between night-shift work and rectal cancer risk was found. In contrast, association between rotating-shift work and increased rectal cancer risk was found. More original studies on this topic are needed to further explore shift-work impacts on rectal cancer risk.

Night-shift work increases morbidity of breast cancer and all-cause mortality: a meta-analysis of 16 prospective cohort studies

2015 ◽  
Vol 16 (11) ◽  
pp. 1381-1387 ◽  
Author(s):  
Xiaoti Lin ◽  
Weiyu Chen ◽  
Fengqin Wei ◽  
Mingang Ying ◽  
Weidong Wei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Studies ◽  
Shift Work ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Night Shift ◽  
Night Shift Work ◽  
Prospective Cohort Studies ◽  
All Cause Mortality

scholarly journals Association Between Night-Shift Work and Cancer Risk: Updated Systematic Review and Meta-Analysis

2020 ◽  
Vol 10 ◽  
Author(s):  
Aishe Dun ◽  
Xuan Zhao ◽  
Xu Jin ◽  
Tao Wei ◽  
Xiang Gao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Risk ◽  
Shift Work ◽  
Meta Analysis ◽  
Night Shift ◽  
Night Shift Work
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