scholarly journals The Role and Impact of Salivary Zn Levels on Dental Caries

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Milaim Sejdini ◽  
Agim Begzati ◽  
Sami Salihu ◽  
Sokol Krasniqi ◽  
Nora Berisha ◽  
...  

Introduction. Minimal attention has been given to the role of salivary microelements, the importance they have in reducing the intensity of caries, and the effect of caries prophylaxes.Aim. This research aimed to determine the concentration and quantity of Zn and its impact on the prevention and the reduction of the intensity of caries in schoolchildren aged 12-13 years with permanent dentition.Methods. For this research, we analyzed the stimulated and nonstimulated full saliva of 106 schoolchildren divided into three groups by mean decayed, missing, and filled teeth (DMFT) index. The control group consisted of 25 caries-free children, the second group had 47 children with mean DMFT index of 1 to 6, and the third group had 34 children with DMFT index of ≥ 6. Complete saliva was collected from all children in a sterile test tube.Results. The concentration of Zn in saliva before stimulation in caries-free children has variations of the order of 0.001+ to 0.01 mmol/l. The maximum concentration after stimulation is 6.72 mmol/l, while the maximum value is 64.38 mmol/l.Conclusion. The Zn concentration in the stimulated saliva showed a significant increase in the group of caries-free children and could be described as a positive value for the reduction of caries.

2009 ◽  
Vol 46 (5) ◽  
pp. 529-531 ◽  
Author(s):  
Mahmoud Al-Dajani

Objective: To evaluate the prevalence of dental caries in patients with cleft lip and/or palate and their cleft-free sibling controls. Methods: The two subject groups (patient and control) comprised 106 participants. The former group consisted of 53 patients with cleft lip and/or palate, aged 12 to 29 years, who visited the Oral and Maxillofacial Surgery Hospital at Damascus University of Syria. The control group consisted of the patients’ siblings who had no clefts, and they were sex matched to the patient group. Dental caries were examined clinically and were reported using the decayed, missing, and filled permanent teeth (DMFT) index. The DMFT scores were compared between the two groups. Results: The author found an overall association of dental caries with the presence of cleft lip and/or palate (odds ratio  =  2.52; 95% confidence interval  =  1.389–4.574; p < .05). The DMFT index scores were proportionally higher in patients with cleft lip and/or palate compared with the control group (p < .001). Conclusion: Subjects with cleft lip and palate are susceptible to dental caries independently of socioeconomic status.


2021 ◽  
Vol 17 (8) ◽  
pp. 47-50
Author(s):  
O.O. Havrylov ◽  
M.L. Gomon

Background. The role of magnesium in the treatment of alcohol withdrawal with delirium is indefinite, although it is well known about its participation in the pathogenesis of this severe condition. The study was aimed to reveal the benefits and disadvantages of the sedation with added magnesium sulfate in comparison with traditional sedative therapy. Materials and methods. In our study, we tested 40 treated patients, which were randomized in two groups. We controlled the level of sedation by the Richmond agitation-sedation scale. The target level of sedation was between 0 and –2 points. We maintained this level in all the patients. In all groups, we evaluated the following values: duration of delirium, mean arterial pressure, pulse, the level of serum magnesium, cortisol and serotonin, laboratory indicators of kidneys, and liver condition. In the control group, we carried out the sedation with 10–20 mg of diazepam every 4–6 hours with infusion of barbiturates as needed. The treatment in the research group was identical with addition of magnesium sulfate 50 mg/kg every 8 hours. Results. The results of the study demonstrated that the duration of delirium is significantly lower in the research group in comparison with the control (p < 0.05). We found hypomagnesemia in almost half of the patients. The indicators of haemodynamics such as mean arterial pressure and pulse were significantly lower in both groups on the third day (p < 0.05). We found 4 cases (20 %) of hypotension in the research group and 2 cases (10 %) in the control group. The study of the dynamics of serum cortisol and serotonin showed the significant difference on the third day in both groups (p < 0.05). We found no difference in these laboratory parameters on the third day between groups (p ≥ 0.05). There was no significant difference between the laboratory indicators of kidneys and liver condition in both groups (p ≥ 0.05). Conclusions. The use of magnesium sulfate allowed decreasing the duration of delirium but had an excessive effect on haemodynamics. Such biomarkers as serum cortisol and serotonin didn’t verify the effect of magnesium sulfate.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1208-1212
Author(s):  
Kuzhalvaimozhi P ◽  
Vignesh Ravindran ◽  
Subhashini V C

Anterior crossbite is a type of malocclusion involving anteroposterior alignment, which results from an abnormal axial inclination of the anterior maxillary teeth. Dental caries is a chronic disease affecting patients and adults. Due to improper oral hygiene management in individuals with a crossbite, the incidence of caries could be higher. Hence a study was conducted to assess the dental caries status in patients with anterior crossbite and also compare with patients without anterior crossbite. The present study consisted of 56 patients divided into two groups: patients with anterior crossbite and patients without anterior crossbite. 89000 Case sheets were reviewed from the dental treatment records for DMFT index in patients with and without anterior crossbite from June 2019 to March 2020. In both groups, parameters such as Decayed- Missing - Filled (DMFT) score was recorded. Data were subjected to the Mann Whitney U test in SPSS software. Results showed higher DMFT score was seen in patients without anterior crossbite. Mean DMFT Index for case group (patients with anterior crossbite) is 2.04, and Mean DMFT Index for the control group (patients without anterior crossbite) is 2.93. The difference was not statistically significant (P-value - 0.072). Within the limitations of the study, dental caries status in patients with anterior crossbite is good compared with patients without anterior crossbite.


2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Sri Raharso ◽  
Sri Surjani Tjahjawati ◽  
Maya Setiawardani

The purpose of this research was to determine the role of music and genre of music that produces the fastest typing speeds in words per minute. Respondent of this research divided into two groups. The first group is a control group that learned keyboarding skill without music, the rest group learned keyboarding skill with music. The music that used in that experiments coming from Mavis Beacon Teaches Typing 26. The number of the word per minute for each respondent was recorded, three times, at the beginning, in the middle, and the end of the course; labeled by Kstart, Kmiddle, and Kend. In spite of identifying role of genre music to typing performance, the second group typed predetermined line while listening to different predetermined music. The genre categories uses were jazz, blues, rock, reggae, degung (Sundanese music), and classic. The number of words per minute for each respondent was recorded. Every respondent has three trials were run. The recorded information was compared. The result of this experiment showed that music played a significant role to shape typing performance. Second, this experiment showed that rock music produced the fastest typing speeds. Blues produced the second fastest typing speed. Jazz produces the third fastest typing speed.


2012 ◽  
Vol 02 (02) ◽  
pp. 06-09 ◽  
Author(s):  
Mithra N. Hegde ◽  
Suchetha Kumari ◽  
Nidarsh Hegde ◽  
Shilpa Shetty ◽  

AbstractThe aim of the present study is to evaluate the status of salivary nitric oxide in patients with dental caries. The study consisted of 80 individuals. According to DFMT index, the subjects were divided into control group (DMFT=0) and study group (DMFT>5). Saliva sample was collected from each subject. Nitric oxide concentration was measured as total nitrates and nitrites by the Griess reaction method. The results of this study show that the presence of NO and its metabolites in saliva of adults with natural healthy teeth is significantly higher compared to high risk group, suggesting the protective role of NO in relation to caries. From the study it can be concluded that highly significant increase of nitrates and nitrites in stimulated saliva of high caries risk group could be the host defense response opposing bacterial growth. The obtained results support the role of NO as modulator of bacterial proliferation and suggest that increased NO production might contribute to lower caries incidence in adults.


2021 ◽  
Vol 45 (4) ◽  
pp. 265-268
Author(s):  
Akhilesh Sharma ◽  
Priya Subramaniam

Background and objectives: Role of salivary zinc to dental caries and body weight has not been studied extensively in children. The aim of the present study was to evaluate the relationship between salivary zinc and caries in overweight/obese Indian children. Study design: One hundred and sixty children aged 8–12 years of both genders were divided into two groups of eighty each based on their body mass index into normal weight and overweight/obese. Each child was assessed for their caries experience in primary and permanent dentition. Unstimulated salivary samples were collected from each child to estimate zinc levels by atomic absorption spectrophotometer. Data was subjected to statistical analysis. Results: The mean caries score among the overweight/obese children was 2.2±3.9 and 0.7±1.5 in the primary and permanent dentition respectively compared to the 2.0±2.6 and 0.2±0.5 respectively among normal weight children. Mean salivary zinc levels in overweight/obese children were 0.36±0.27 ppm compared to normal weight children of 0.81±0.46 ppm. Conclusion: Overweight/obese children demonstrated significantly lower salivary zinc levels and higher caries experience in permanent dentition. Salivary zinc levels showed a positive but weak association to caries in permanent dentition in both groups. Salivary zinc levels showed a negative non-significant correlation to caries in primary dentition among the children with higher BMI.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S622-S623
Author(s):  
D Piątek ◽  
S Jarmakiewicz-Czaja ◽  
I Korona-Głowniak ◽  
A Malm ◽  
J Sztembis ◽  
...  

Abstract Background Inflammatory bowel disease (IBD), including patients’ diet, way of treatment and general health may have an impact on teeth condition. Due to multifactorial nature of caries that its linked to susceptibility of hard tooth tissues, cariogenic microorganisms and presence of fermentable carbohydrates, the course of disease can be modified at many levels. The aim of the study was to assess dental caries experience in adult patients with Crohn’s disease (CD) and ulcerative colitis (UC). Methods The study involved 224 individuals: 98 with diagnosed CD, 75 with UC and 51 of control group (CG) with mean age 34.7. The complete assessment of the hard tooth tissues based on the DMFT index (decayed D, missing M, filled F teeth) was performed. Results There were no statistically significant differences between the examined groups in terms of DMFT index values, however, a statistically significant difference was found in the number of teeth with caries (D) (mean 3.99, 3.05 and 1.96 for CD, UC and CG respectively; H=13.55 p &lt; 0.05). All groups had higher mean D values in men than women, and achieved the highest mean value in CD group (4.78) compared with UC (3.68) and healthy controls (2.06)(H=8.71 p &lt; 0.05). The results of D values for CG obtained in our study confirm the literature data for healthy population aged 35–44 in Poland (mean D~2). The number of lost teeth (M) in the studied population was high and amounted to 5.47, 5.25 and 3.94 for the examined groups, respectively. A thorough analysis showed that in the group of men the difference in the M value was statistically significant at 5.83, 5.94 and 1.11 for CD, UC and CG respectively (H=15.84 p &lt; 0.05). Statistically significant differences (H=6.21 p &lt; 0.05) were observed in the number of filled teeth (F), without secondary caries, which highest value was recorded in CG (10.76) and the lowest in the CD group (8.93). Conclusion The highest D and M values were observed in patients with CD, especially in men, which proves the intensity and activity of dental caries disease in this group.


2020 ◽  
pp. 32-36
Author(s):  
А.Ф. Бухаров ◽  
Д.Н. Балеев ◽  
П.О. Маврина ◽  
А.В. Корнев ◽  
Н.А. Еремина

Показаны перспективы семейственного отбора по комплексу морфометрических параметров. Объектом исследований служили семена четырех сортов столовой моркови. Изучены семена индивидуально отобранных растений сортов Шантене 2461 (стандарт), Рогнеда, Лосиноостровская 13, Арго. Измерения проводили с использованием штангенциркуля, видеоокуляра DCM 300 MD микроскопа Микромед 1 при 40-кратном увеличении. Показаны существенные различия по размерам семян, эндосперма и зародыша как на уровне сортовых популяций, так и на уровне отобранных из них семей. Выявлены семьи, которые существенно превышали среднее значение сортовой популяции на 4,8–6,9% по длине семени, 5,4–6,3% по длине эндосперма и 9,2–16,0% по длине зародыша. Коэффициент вариации в пределах сортовых популяций изменялся от 8,1% до 12,8% по длине семени, от 9,9% до 11,4% по длине эндосперма и от 12,2% до 16,1% по длине зародыша, указывая на относительно низкую степень изменчивости изученных параметров. Однако лимиты изменчивости изученных признаков обеспечивают возможности для проведения эффективного отбора. Выявлена тесная корреляционная связь между линейными размерами семени и эндосперма от 0,724 до 0,925. Отсутствие жестких корреляционных связей между линейными размерами зародыша и эндосперма обеспечивают широкие возможности для комбинационной селекции. Значению индекса IЗ/Э большая часть семей (65%) принадлежит к третьему классу, и только отдельные семьи преодолели 40%-й барьер по этому показателю и их можно отнести к четвертому классу. Максимальное значение индекса IЗ/Э имели: семья №3 (0,43) из сорта Арго, семьи №1 (0,42) и №2 (0,41) из сорта Лосиноостровская 13, семьи №2 (0,41) и №5 (0,41) из сорта Рогнеда. Показана важная роль индекса IЗ/Э (отношение длины зародыша к длине эндосперма) для оценки семян по степени недоразвития зародыша и использования его при отборе. The prospects of family breeding by a complex of morphometric parameters are shown. The object of research was the seeds of four varieties of carrots. The seeds of individually selected plants of varieties Chantene 2461 (standard), Rogneda, Losinoostrovskaya 13, Argo were studied. Measurements were carried out using a caliper, DCM 300 MD microscope Micromed 1 video eyepiece at 40 magnification. Significant differences in the sizes of seeds, endosperm and embryo are shown both at the level of varietal populations and at the level of families selected from them. Families were identified that significantly exceeded the average value of the varietal population by 4.8–6.9% along the length of the seed, 5.4–6.3% along the length of the endosperm and 9.2–16.0% along the length of the embryo. The coefficient of variation within varietal populations varied from 8.1% to 12.8% along the length of the seed, from 9.9% to 11.4% along the length of the endosperm and from 12.2% to 16.1% along the length of the embryo a relatively low degree of variability of the studied parameters. However, the variability limits of the studied traits provide opportunities for effective breeding. A close correlation between the linear sizes of the seed and endosperm from 0.724 to 0.925 was revealed. The absence of rigid correlation between the linear dimensions of the embryo and endosperm provides ample opportunities for combinational selection. Most of the families (65%) belong to the third class with the IZ/E index value, and only individual families have overcome the 40% barrier in this indicator and can be attributed to the fourth class. The maximum value of the IE/E index was for the selected family No. 3 (0.43) from the Argo variety, family No1 (0.42) and No2 (0.41) from the Losinoostrovskaya 13 variety, family No2 (0.41) and No5 (0.41) from the Rogneda variety. The important role of the IE/E index (the ratio of the length of the embryo to the length of the endosperm) for assessing seeds by the degree of underdevelopment of the embryo and its use in selection is shown.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Esat Korgali ◽  
Gokce Dundar ◽  
Kubra Acikalin Coskun ◽  
Melih Akyol ◽  
Yusuf Tutar ◽  
...  

Introduction. Strontium salts are anti-irritants for chemically induced sensory irritation. Interstitial cystitis is a painful disease without definitive therapy. The aim of the study was to determine the effect of strontium in bladder with experimental interstitial cystitis model. Material and Methods. Rats’ bladders in control group were instilled with NaCl. Second group was instilled with E. coli LPS. Third group was instilled with strontium. Fourth group was initially instilled with strontium and then LPS. Fifth group was instilled with LPS initially and then strontium. Urine of rats was collected at the beginning and end of the study. Results. Histamine and TNF-α changes were statistically significant in the second group but were not significant in the third group. When we compared the histamine levels of second via fourth and fifth groups the changes were statistically not significant. When we compared the TNF-α levels of second via fourth and fifth groups the changes were statistically significant. Conclusions. In our model, strontium did not make any significant changes in histopathology or histamine levels; however, it significantly reduced the levels of TNF-α. Given the role of TNF-α in the physiopathology of interstitial cystitis, these results suggested that further studies are required to evaluate the potential use of strontium in the management of interstitial cystitis.


Author(s):  
Olga Borisovna Zhdanova ◽  
Amina Aslanovna Haidarova ◽  
Ludmila Alexandrovna Napisanova ◽  
Dimitri Rossohin ◽  
Olga Lozhenicina

Background Trichinosis is a parasitic disease caused by ingestion larvae of Trichinella spiralis (TS). In Russia trichinosis of pigs is widely spreaded. Invasion occurs when human or animal eat contaminated meat. TS is adapted to many hosts, and due to its wide spread, there has always been a demand of safe alternatives for this infection. A lot of information has been gathered about sharp decreasing of quantity of trichinae in muscles at repeated invasion of predators. We took a chance of applying antigen to TS as a vaccine, however, rate of immunogenetic effect wasn't high. Therefore, in an experimental work, we decided to inject vaccine and immunomodulators together at the same time. Material and Methods We subjected rats infected with TS to conventional treatment (vaccine) along with Cina 6cH. There were five groups as follows: The first group was injected antigen alone and no immunomodulators; the second group was injected antigen and Ronkoleikin; the third group was injected antigen and Sodium nucleinate, the fourth group was injected antigen and Cina C6cH; and the fifth group was a control group, which was injected neither antigen nor immunomodulators. After 21 days of vaccination (or giving homeopathic medicine) rats were contaminated TS in a dose of 200germs/animal. Results The rats were euthanized after two months. They we then analysed for stomach contents and quantity of worms in muscles. The highest number of worms were found in fifth group (no antigen and no immunomodulators) (more than 2600 worms/animal. The quantity of worms in the second group (injection of antigen and Ronkoleikin) was in four times less than in the control group. The most efficient substance was Ronkoleikin (900+160 worms/animal); Sodium nucleinate (1100+100 worms/per animal); Cina C6cH (1400+50 worms/animal). Conclusion Cina C6cH along with and others immunomodulators was able to exhibit protective effect against experimental trichinosis. Further research with rigorous designs is needed to explore the role of Cina in Trichinella spiralis.


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