scholarly journals Gastric Linitis Plastica and Peritoneal Carcinomatosis as First Manifestations of Occult Breast Carcinoma: A Case Report and Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Mara Mantiero ◽  
Giovanni Faggioni ◽  
Alice Menichetti ◽  
Matteo Fassan ◽  
Valentina Guarneri ◽  
...  

Gastric linitis plastica is a diffuse involvement of the stomach walls by neoplastic cells. It represents about 3–19% of primitive gastric adenocarcinomas, but it can also be the manifestation of a metastatic disease. Breast cancer is the most frequent malignancy in women, and the metastatic spread to the stomach occurs in less than 10% of the cases. We present an unusual case of gastric linitis plastica and peritoneal carcinomatosis as manifestations of an occult breast cancer in a 53-year-old woman. Imaging and endoscopic evaluation were not able to discriminate a primary from a secondary gastric lesion. The histological evaluation excluded the diagnosis of a primary gastric neoplasia. The IHC profile was consistent with the diagnosis of metastases from the breast cancer. Due to the hormonal receptors’ positivity, we started therapy with fulvestrant (500 mg, day 0, 14, and 28 and every 28 days thereafter by intramuscular injection). After 20 months, the same therapy is still ongoing and well tolerated, while the patient is in good condition with improvement of the dysphagia. Almost 2 years after the diagnosis of linitis plastica, the primitive breast lesion is still occult.

2017 ◽  
Vol 10 (3) ◽  
pp. 992-997 ◽  
Author(s):  
Ricardo L.B. Costa ◽  
Rubens B. Costa-Filho ◽  
Marilin Rosa ◽  
Brian J. Czerniecki

Breast cancer is the most common tumor among women, and approximately 6% of the patients have de novo metastatic breast cancer. Occult breast cancer accounts for only 0.1–0.8% of the cases and most commonly presents with axillary lymphadenopathy. Scalp metastases are rare and have been described as a sign of progression or widespread metastatic disease. Here, we describe a rare case of de novo metastatic breast cancer to the scalp as the single site of spread and without an identifiable primary breast tumor.


2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Lonzetta Neal ◽  
Nicole Sookhan ◽  
Carol Reynolds

Occult breast cancer has frequently been described as presenting as axillary lymph node metastases but rarely as gastrointestinal metastases, Varadarajan et al. (2007). In extremely rare situations, cancerous lesions identified in the gastrointestinal tract have been determined to be metastatic lesions from primary breast cancers, Taal et al. (2000). We report a case of an occult lobular adenocarcinoma presenting as gastrointestinal metastases. It is essential that the possibility of lesions found in the gastrointestinal tract originating from distant or occult cancers be considered in order that appropriate therapeutic options may be discussed and considered early after diagnosis.


1994 ◽  
Vol 32 (3) ◽  
pp. 327-330 ◽  
Author(s):  
Peter L. Davis ◽  
Thomas B. Julian ◽  
Melinda Staiger ◽  
Kathleen B. Harris ◽  
Dennis Borochovitz ◽  
...  

1980 ◽  
Vol 191 (1) ◽  
pp. 8-12 ◽  
Author(s):  
GORDON F. SCHWARTZ ◽  
ARTHUR S. PATCHEFSKY ◽  
STEPHEN A. FEIG ◽  
GARY S. SHABER ◽  
AMORY B. SCHWARTZ

Author(s):  
Inês Morais Rodrigues ◽  
Fernando Igreja ◽  
Isabel Riscado ◽  
Rosa Madureira ◽  
Ana Nobre Pinto

2001 ◽  
Vol 8 (10) ◽  
pp. 850-855 ◽  
Author(s):  
P. J. Tanis ◽  
E. E. Deurloo ◽  
R. A. Vald�s Olmos ◽  
E. J.Th. Rutgers ◽  
O. E. Nieweg ◽  
...  

2009 ◽  
Vol 70 (3) ◽  
pp. 552-553 ◽  
Author(s):  
Advitya Malhotra ◽  
Praveen Guturu ◽  
Mohammed S. Basim ◽  
Gottumukkala S. Raju

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