scholarly journals Occult Breast Carcinoma Presenting as Gastrointestinal Metastases

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Lonzetta Neal ◽  
Nicole Sookhan ◽  
Carol Reynolds

Occult breast cancer has frequently been described as presenting as axillary lymph node metastases but rarely as gastrointestinal metastases, Varadarajan et al. (2007). In extremely rare situations, cancerous lesions identified in the gastrointestinal tract have been determined to be metastatic lesions from primary breast cancers, Taal et al. (2000). We report a case of an occult lobular adenocarcinoma presenting as gastrointestinal metastases. It is essential that the possibility of lesions found in the gastrointestinal tract originating from distant or occult cancers be considered in order that appropriate therapeutic options may be discussed and considered early after diagnosis.

The Breast ◽  
1997 ◽  
Vol 6 (3) ◽  
pp. 143-145 ◽  
Author(s):  
C.I. Perre ◽  
V.C.M. Koot ◽  
E.P.A. van der Heijden ◽  
V. Vossen ◽  
J.R. de Jong ◽  
...  

Oncology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Vilma Madekivi ◽  
Antti Karlsson ◽  
Pia Boström ◽  
Eeva Salminen

Background: Nomograms can help in estimating the nodal status among clinically node-negative patients. Yet their validity in external cohorts over time is unknown. If the nodal stage can be estimated preoperatively, the need for axillary dissection can be decided. Objectives: The aim of this study was to validate three existing nomograms predicting 4 or more axillary lymph node metastases. Method: The risk for ≥4 lymph node metastases was calculated for n = 529 eligible breast cancer patients using the nomograms of Chagpar et al. [Ann Surg Oncol. 2007;14:670–7], Katz et al. [J Clin Oncol. 2008;26(13):2093–8], and Meretoja et al. [Breast Cancer Res Treat. 2013;138(3):817–27]. Discrimination and calibration were calculated for each nomogram to determine their validity. Results: In this cohort, the AUC values for the Chagpar, Katz, and Meretoja models were 0.79 (95% CI 0.74–0.83), 0.87 (95% CI 0.83–0.91), and 0.82 (95% CI 0.76–0.86), respectively, showing good discrimination between patients with and without high nodal burdens. Conclusion: This study presents support for the use of older breast cancer nomograms and confirms their current validity in an external population.


2004 ◽  
Vol 90 (1) ◽  
pp. 107-111 ◽  
Author(s):  
Görken Bilkay İlknur ◽  
Alanyali Hilmi ◽  
Canda Tülay ◽  
Çetinayak Oguz ◽  
Sengiz Selma ◽  
...  

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