scholarly journals Green and Efficient Extraction of Resveratrol from Peanut Roots Using Deep Eutectic Solvents

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Jingnan Chen ◽  
Xingxing Jiang ◽  
Guolong Yang ◽  
Yanlan Bi ◽  
Wei Liu
Keyword(s):  
Choline Chloride ◽  
Deep Eutectic Solvents ◽  
Extraction Yield ◽  
Box Behnken Design ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Efficient Extraction ◽  
Ultrasonic Assisted Extraction ◽  
Solid Liquid ◽  
Total Extraction

Deep eutectic solvents (DESs), a new group of ecofriendly solvent combined with the ultrasonic-assisted extraction (UAE) technique, were first successfully used for extraction of resveratrol from peanut roots. Resveratrol in the extract was analyzed and quantified using a HPLC-UV method. A series of DESs consisting of choline chloride (ChCl) and 1,4-butanediol, citric acid, and ethylene glycol were formulated, finding ChCl/1,4-butanediol was a most proper extraction system. The optimal extraction parameters were obtained using a Box–Behnken design (BBD) test combined with response surface methodology as follows: 40% of water in ChCl/1,4-butanediol (1/3, g/g) at 55°C for 40 min and solid/liquid ratio of 1:30 g/mL. The total extraction content and extraction yield of resveratrol from peanut roots could reach 38.91 mg/kg and 88.19%, respectively, under such optimal conditions. The present study will provide a typical example for using DESs to extract natural bioactive compounds from plants.

scholarly journals Efficient Extraction of Anti-Inflammatory Active Ingredients from Schefflera octophylla Leaves Using Ionic Liquid-Based Ultrasonic-Assisted Extraction Coupled with HPLC

Molecules ◽  
2019 ◽  
Vol 24 (16) ◽  
pp. 2942 ◽  
Author(s):  
Xuqiang Liu ◽  
Yun Niu ◽  
Jieqing Liu ◽  
Mengjun Shi ◽  
Ruian Xu ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Extraction Yield ◽  
Extraction Rate ◽  
Optimal Conditions ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Efficient Extraction ◽  
Ultrasonic Assisted Extraction ◽  
Anti Inflammatory ◽  
Solid Liquid

Schefflera octophylla (Lour.) Harms, a kind of traditional Chinese medicine (TCM), is commonly used for anti-inflammatory, analgesic, rheumatism, fever, and hemostasis therapy. In our previous studies, two major triterpenoids were isolated and identified from leaves of S. octophylla, and evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide production in RAW264.7 cells; both of them displayed significant anti-inflammatory activities at their noncytotoxic concentrations. Therefore, it is very useful to establish an efficient and green extraction method to isolated the two major triterpenoids from leaves of S. octophylla. In this paper, ionic liquid based ultrasonic-assisted extraction (ILUAE) was successfully applied to extract the two major triterpenoids from leaves of S. octophylla. Four single factors (ionic liquids (ILs) concentration, solid–liquid ratio, centrifugal speed, mesh number), with a greater impact on extraction rate, were selected from a variety of influencing factors, and the optimal conditions were obtained by Box–Behnken response surface methodology (RSM). Under optimal conditions, the total extraction yield and extraction rate of two triterpenoids were 288.03 mg/g and 28.80%, respectively, which was 6.80% higher than that of 70% Ethanol (220 mg/g and 22%, respectively).

Comparative Evaluation of Total Flavonoid Contents in Different Parts of Ficus microcarpa

2012 ◽  
Vol 560-561 ◽  
pp. 423-427
Author(s):  
Qiang Lin ◽  
Hao Yue Du ◽  
You Bin Liu ◽  
Yu Kai Chen ◽  
Jing Xu
Keyword(s):  
Extraction Yield ◽  
Total Flavonoid ◽  
Extraction Temperature ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ficus Microcarpa ◽  
Ultrasonic Assisted Extraction ◽  
Pharmaceutical Properties ◽  
Solid Liquid ◽  
Different Parts

This study was designed to comparative evaluate total flavonoid contents (TFC) in leaf, aerial root, twig, root and bark parts of Ficus microcarpa L.f. (Moraceace). Ultrasonic-assisted extraction was adopted using benign solvent: ethanol and water to determine the extraction efficiency under the condition of ethanol concentration 40%, solid/liquid ratio of 1:25, extraction time 35 min and extraction temperature at 60 °C. According to the experimental results, the TFC values varied considerably and the extraction yield of 2.67±0.02%, 3.70±0.043%, 2.99±0.04%, 6.56±0.83% and 4.26±0.18% were obtained from different parts, respectively. The root part was characterized as containing a high amount of flavonoids, which might be the active compounds responsible for the pharmaceutical properties of the plant. The study offers theoretic basis for further utilization of the traditional folk herb F. microcarpa.

scholarly journals A Study of the Ionic Liquid-Based Ultrasonic-Assisted Extraction of Isoliquiritigenin from Glycyrrhiza uralensis

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Jingwei Hao ◽  
Jiahui Liu ◽  
Lei Zhang ◽  
Yunrong Jing ◽  
Yubin Ji
Keyword(s):  
Ionic Liquid ◽  
Extraction Procedure ◽  
Extraction Yield ◽  
Glycyrrhiza Uralensis ◽  
Extraction Temperature ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
The Times ◽  
Solid Liquid

We successfully extracted isoliquiritigenin from Glycyrrhiza uralensis through the utilization of an ionic liquid-based ultrasonic-assisted extraction (ILUAE) approach. Briefly, we utilized the solution of 1-butyl-3-methylimidazolium bromide ([BMIM]Br) as solvent and optimized key ILUAE parameters such as solid-liquid ratios, concentrations of ionic liquids, and the times of ultrasonication. Based on a single-factor experiment, we utilized the response surface method (RSM) approach to optimize the extraction procedure. The approach revealed that the optimal energy consumption time was 120 min, with the ultrasonic extraction temperature of 60°C. Using these optimized parameters together with the solid-liquid ratio (dried G. uralensis powder: [BMIM]Br of 0.3 mol/L) of 1 : 16.163 and the [BMIM]Br of 0.3 mol/L, we achieved a 0.665 mg/g extraction yield. Overall, these findings thus indicate that we were able to effectively use ILUAE as an efficient approach to reliably extract isoliquiritigenin in a reproducible and environmentally friendly manner.

scholarly journals Optimization Studies on the Extraction of Flavone Di-C-glycosides from Premna fulva Craib by Deep Eutectic Solvents

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Yueyuan Chen ◽  
Jiaoyang Dang ◽  
Xiaojie Yan ◽  
Fenglai Lu ◽  
Dianpeng Li
Keyword(s):  
Choline Chloride ◽  
Deep Eutectic Solvents ◽  
Microstructural Alterations ◽  
Solid Ratio ◽  
Macroporous Resins ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Extraction Solvents ◽  
Ultrasonic Assisted Extraction ◽  
Novel Strategy

Deep eutectic solvents (DESs) are emerging as new extraction solvents for the extraction of bioactive compounds from natural plants. In this work, a total of thirteen choline chloride-based DESs were synthesized and evaluated for the simultaneous extraction of five bioactive flavone di-C-glycosides from Premna fulva Craib. DES-F, which was composed of choline chloride and 1,3-propanediol, showed the best extraction efficiency for the flavone di-C-glycosides, exceeding that of the conventional industrial solvent (40% ethanol). Subsequently, the extraction parameters for ultrasonic-assisted extraction (liquid-solid ratio, water content (%) in the selected DES, and extraction time) were optimized using response surface methodology. Furthermore, the microstructural alterations in the samples after extraction were evaluated using scanning electron microscopy. In addition, we further verified the recovery of flavone di-C-glycosides from the DESs using macroporous resins and evaluated the reusability of the DESs as solvents. The results indicated that DES-F was an efficient and sustainable solvent for the extraction of bioactive flavone di-C-glycosides from Premna fulva Craib. Therefore, this novel strategy may represent a sustainable approach for the extraction of bioactive products and could make phytochemistry more attractive and environmentally friendly.

scholarly journals Ionic Liquid-Based Ultrasonic-Assisted Extraction to Analyze Seven Compounds in Psoralea Fructus Coupled with HPLC

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1699 ◽  
Author(s):  
Mengjun Shi ◽  
Juanjuan Zhang ◽  
Cunyu Liu ◽  
Yiping Cui ◽  
Changqin Li ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Extraction Yield ◽  
Environmentally Benign ◽  
Clinical Effects ◽  
Ultrasonic Power ◽  
Assisted Extraction ◽  
Ultrasonic Time ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
Solid Liquid

Psoralea Fructus is widely used in traditional Chinese medicine (TCM), and the content of psoralen, isopsoralen, neobavaisoflavone, bavachin, psoralidin, isobavachalcone, and bavachinin A is the main quality control index of Psoralea Fructus because of its clinical effects. Thus, a fast and environmentally-benign extraction method of seven compounds in Psoralea Fructus is necessary. In this work, an ionic liquid-based ultrasonic-assisted method (ILUAE) for the extraction of seven compounds from Psoralea Fructus was proposed. Several ILs of different types and parameters, including the concentration of ILs, concentration of ethanol (EtOH), solid–liquid ratio, particle size, ultrasonic time, centrifugal speed, and ultrasonic power, were optimized by the Placket–Burman (PB) design and Box–Behnken response surface analysis. Under this optimal condition, the total extraction yield of the seven compounds in Psoralea Fructus was 18.90 mg/g, and significantly greater than the conventional 75% EtOH solvent extraction.

scholarly journals Optimization of ultrasonic-assisted extraction of inulin from Jerusalem artichoke

2019 ◽  
Vol 78 ◽  
pp. 02007
Author(s):  
Lina Yang ◽  
Hongyun Zhang ◽  
Jinghang Huang ◽  
Yafan Zhao ◽  
Danshi Zhu ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Jerusalem Artichoke ◽  
Hot Water ◽  
Ultrasonic Power ◽  
Hot Water Extraction ◽  
Box Behnken Design ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction

An efficient ultrasonic-assisted extraction of inulin from Jerusalem artichoke was investigated by Response Surface Methodology (RSM). The results showed that the yield of ultrasonic-assisted extraction was 62.07 ± 0.39% over the microwave (40.85 ± 0.28%) and hot water extraction (27.42 ± 0.42%). The Box-Behnken Design (BBD) was used to optimize the effects of three parameters (temperature-X1, ultrasonic power-X2 and time-X3) on inulin yield. Analysis of variance showed that the contributions of X1, X3, X12, X13, X22 were significant. The optimal yield of inulin was 82.93 ± 1.03% at 82 °, 120 W and 18 min.

scholarly journals Green and Efficient Extraction of Polysaccharides From Poria cocos F.A. Wolf by Deep Eutectic Solvent

2020 ◽  
Vol 15 (2) ◽  
pp. 1934578X1990070 ◽  
Author(s):  
Weida Zhang ◽  
Shaobo Cheng ◽  
Xiaona Zhai ◽  
Junshe Sun ◽  
Xuefang Hu ◽  
...  
Keyword(s):  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Deep Eutectic Solvents ◽  
Extraction Yield ◽  
Hot Water ◽  
Poria Cocos ◽  
Extraction Solvent ◽  
Molecular Weight Distributions ◽  
Efficient Extraction ◽  
Run Test

Deep eutectic solvents (DESs) were proposed for the extraction of polysaccharides from Poria cocos (PCPs). Six types of DESs were prepared, and the DES composed of choline chloride and oxalic acid was proved to be suitable. Based on the results of single-factor test, the Box-Behnken experimental design with response surface methodology was carried out, giving the optimal extraction conditions including mole ratio of 1:2 (choline chloride:oxalic acid) and extraction 15 minutes at 100°C. Under the optimal extraction conditions, the extraction yield (46.24% ± 0.13%) was 8.6 times higher than that of hot water. The reusability of DES was demonstrated by a 6-run test, and an extraction yield of PCP was 38.40% ± 0.23% after reusing for 6 times without adding any additional chemicals. Moreover, molecular weight distributions of the resulting PCP were analyzed, and then mainly distributed in the range of 753 to 3578 g/mol. Therefore, DESs were proved to be an excellent extraction solvent alternative to the extraction of PCP.

scholarly journals Optimization of Extraction Conditions of Bioactive Compounds by Ultrasonic-Assisted Extraction from Artichoke Wastes

2021 ◽  
Vol 68 (3) ◽  
pp. 658-666
Author(s):  
Izzet Turker ◽  
Hilal Isleroglu
Keyword(s):  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Extraction Process ◽  
Extraction Yield ◽  
Extraction Time ◽  
Total Phenolic ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Extraction Processes ◽  
Ultrasonic Assisted Extraction

In this study, bioactive compounds were extracted by ultrasonic-assisted extraction and classical extraction processes using distilled water as solvent from artichoke leaves which are considered as agricultural wastes. Antioxidant capacity, total phenolic and total flavonoid content values of the obtained bioactive extracts were determined, and extraction yields and times were evaluated to compare the extraction processes. Also, the optimum extraction conditions of ultrasonic-assisted extraction (extraction time and ultrasonic power) which provide the highest extraction yield were determined using D-optimal design by ‘desirability’ function approach. According to the results, bioactive extracts having high antioxidant capacity were obtained at shorter times and higher extraction yields were achieved by ultrasonic-assisted extraction process than classical extraction. The highest extraction yield was estimated as 98.46% with an application of 20.05 minutes of extraction time and 65.02% of ultrasonic amplitude for the ultrasonic-assisted extraction process.

scholarly journals Study on the Extraction of Polyphenols from Blueberry Leaves and their antioxidant properties

2021 ◽  
Vol 251 ◽  
pp. 02059
Author(s):  
Fenghong Liu ◽  
Xianhao Cheng ◽  
Wenguang Liu ◽  
Jing Miu ◽  
Jiahui Wang ◽  
...  
Keyword(s):  
Ethanol Concentration ◽  
Orthogonal Experiment ◽  
Antioxidant Properties ◽  
High Yield ◽  
Assisted Extraction ◽  
Ultrasonic Time ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
Solid Liquid ◽  
Blueberry Leaves

Blueberry leaf as materials, ethanol ultrasonic assisted extraction of blueberry polyphenols, ethanol concentration and solid-liquid ratio on blueberry ultrasonic time leaves influence the yield of polyphenols were researched, and the orthogonal experiment to optimize the ethanol ultrasonic assisted extraction technological conditions of blueberry leaf polyphenol polyphenols was used. The results showed that the optimal extraction conditions of polyphenols from blueberry leaves were as follows, 9.06% with 4min ultrasonic time, 80% ethanol concentration and 1:45 (g/mL) ratio. Ultrasonic assisted extraction is a convenient and high yield method, which is suitable for the extraction of polyphenols from blueberry leaves.

Ultrasonic-Assisted Extraction and Antioxidant Activities of Polysaccharides from Radix astragali

2013 ◽  
Vol 864-867 ◽  
pp. 549-552 ◽  
Author(s):  
Ming Wu ◽  
Chuan Fu Ma ◽  
Jun Man Kan ◽  
Li Quan Guo
Keyword(s):  
Superoxide Anion ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Ultrasonic Power ◽  
Extraction Temperature ◽  
Radix Astragali ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
Solid Liquid

Ultrasonic-assisted extraction (UAE) method was used to polysaccharides from Radix Astragali (RAP), and the orthogonal test was applied to optimize extraction conditions. Furthermore, the antioxidant activities of RAP were evaluated by DPPH and superoxide anion radical scavenging activities assay. The results indicated that the optimal conditions for RAP extraction as followings: solid/liquid ratios of 1:20, extraction time of 10 min, ultrasonic power of 65 W and extraction temperature of 60°C. Meanwhile, RAP had relatively higher scavenging activities on DPPH and superoxide anion radicals.

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