scholarly journals Development of an Amperometric Glucose Biosensor Based on the Immobilization of Glucose Oxidase on the Se-MCM-41 Mesoporous Composite

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Sabriye Yusan ◽  
Mokhlesur M. Rahman ◽  
Nasir Mohamad ◽  
Tengku M. Arrif ◽  
Ahmad Zubaidi A. Latif ◽  
...  
Keyword(s):  
Glucose Oxidase ◽  
Ph Value ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Calibration Plot ◽  
Carbon Paste ◽  
Linear Calibration ◽  
Effects Of Ph ◽  
Paste Electrode ◽  
Mcm 41

A new bioenzymatic glucose biosensor for selective and sensitive detection of glucose was developed by the immobilization of glucose oxidase (GOD) onto selenium nanoparticle-mesoporous silica composite (MCM-41) matrix and then prepared as a carbon paste electrode (CPE). Cyclic voltammetry was employed to probe the catalytic behavior of the biosensor. A linear calibration plot is obtained over a wide concentration range of glucose from 1 × 10−5 to 2 × 10−3 M. Under optimal conditions, the biosensor exhibits high sensitivity (0.34 µA·mM−1), low detection limit (1 × 10−4 M), high affinity to glucose (Km = 0.02 mM), and also good reproducibility (R.S.D. 2.8%, n=10) and a stability of about ten days when stored dry at +4°C. Besides, the effects of pH value, scan rate, mediator effects on the glucose current, and electroactive interference of the biosensor were also discussed. As a result, the biosensor exhibited an excellent electrocatalytic response to glucose as well as unique stability and reproducibility.

Glucose biosensor based on immobilization of glucose oxidase on a carbon paste electrode modified with microsphere-attached l -glycine

2017 ◽  
Vol 64 (5) ◽  
pp. 745-753 ◽  
Author(s):  
Soner Donmez ◽  
Fatma Arslan ◽  
Nurşen Sarı ◽  
Elvan Hasanoğlu Özkan ◽  
Halit Arslan
Keyword(s):  
Glucose Oxidase ◽  
Carbon Paste Electrode ◽  
Glucose Biosensor ◽  
Carbon Paste ◽  
Paste Electrode

scholarly journals Electrochemical determination of atenolol and propranolol using a carbon paste sensor modified with natural ilmenite

2021 ◽  
Vol 19 (1) ◽  
pp. 875-883
Author(s):  
Nevila Broli ◽  
Majlinda Vasjari ◽  
Loreta Vallja ◽  
Sonila Duka ◽  
Alma Shehu ◽  
...  
Keyword(s):  
Carbon Paste Electrode ◽  
Beta Blockers ◽  
High Sensitivity ◽  
Modified Carbon Paste Electrode ◽  
Current Response ◽  
Carbon Paste ◽  
Linear Calibration ◽  
Pharmaceutical Tablets ◽  
Paste Electrode

Abstract In this study, a simple voltammetric method was reported for independent determination of propranolol (PROP) and atenolol (ATN) in pharmaceutical tablets using carbon paste electrode modified with natural Ilmenite (CPE-I). The analytical performance of the modified sensor was evaluated using the square wave voltammetry and cyclic voltammetry for determination of both β(beta) blockers in 0.1 mol L−1 of sulfuric acid solution (H2SO4). The signal obtained with modified carbon paste electrode in 0.1 mol L−1 of H2SO4 showed a good electrocatalytic activity toward the oxidations of PROP and ATN compared with the bare one. The enhanced oxidation peak current response can be attributed to the catalytic effect of the ilmenite nanomaterial incorporated into the carbon paste electrode. Under optimal condition, good linear calibration curves were obtained ranging from 0.20 to 8.9 mmol L−1 for PROP and 2.0 to 9.9 µmol L−1 for ATN, with detection limits of 80 and 0.31 µmol L−1, respectively. The CPE-I sensor had good repeatability and reproducibility (RSD ≤ 3.2%) and high sensitivity for the detection of both ATN and PROP. The proposed sensor was applied for detection of these drugs in pharmaceutical tablets. The obtained results indicate that the voltammetric CPE-I sensor could be an alternative method for the routine quality control of the β blockers in complex matrices.

scholarly journals Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3757
Author(s):  
Gabriela Valdés-Ramírez ◽  
Laura Galicia
Keyword(s):  
Ferulic Acid ◽  
Glucose Oxidase ◽  
Aqueous Media ◽  
Glucose Biosensor ◽  
Single Step ◽  
Coefficient Of Determination ◽  
The Novel ◽  
Carbon Paste ◽  
Glucose Response ◽  
Glucose Biosensors

A biosensing membrane base on ferulic acid and glucose oxidase is synthesized onto a carbon paste electrode by electropolymerization via cyclic voltammetry in aqueous media at neutral pH at a single step. The developed biosensors exhibit a linear response from 0.082 to 34 mM glucose concentration, with a coefficient of determination R2 equal to 0.997. The biosensors display a sensitivity of 1.1 μAmM−1 cm−2, a detection limit of 0.025 mM, and 0.082 mM as glucose quantification limit. The studies reveal stable, repeatable, and reproducible biosensors response. The results indicate that the novel poly-ferulic acid membrane synthesized by electropolymerization is a promising method for glucose oxidase immobilization towards the development of glucose biosensors. The developed glucose biosensors exhibit a broader linear glucose response than other polymer-based glucose biosensors.

Iron Nanoparticles Coated with Nanostructured Carbon: Synthesis and Application in Glucose Biosensors

2017 ◽  
Vol 899 ◽  
pp. 216-220
Author(s):  
R.L. Roman ◽  
J.P.Z. Gonçalves ◽  
S.C. Fernandes ◽  
Lucinao Luiz Silva ◽  
J. Dal Magro ◽  
...  
Keyword(s):  
Glucose Biosensor ◽  
Performance Evaluations ◽  
Carbon Paste ◽  
Hydrothermal Route ◽  
Sensor Performance ◽  
Carbon Coated ◽  
New Type ◽  
Co Precipitation ◽  
Paste Electrode ◽  
Oxidation Of Glucose

Nanowires of carbon coated ferric oxide (Fe2O3/C) have been studied to be applied at an electrochemical glucose biosensor as a new type of carbon paste electrode (CPE) modifier. The Fe2O3/C was synthesized by adapting co-precipitation hydrothermal route. Firstly, amperometric sensor based on a modified CPE doped with Fe2O3 has been developed and compared with CPE doped with Fe2O3/C for hydrogen peroxide (H2O2) determination. The performance evaluations for the modified materials and sensors were studied in detail through cyclic voltammetry (CV) method. After, the electrochemical sensor performance was also evaluated for glucose oxidase (GOx) response biosensor due to considerable interest in the blood sugar control. The results demonstrate that the GOx retains its biocatalytic activity toward the oxidation of glucose and that the bioelectrode modified by the Fe2O3/C matrix has potential for use in biosensors and other bioelectronics devices.

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