scholarly journals Lycium barbarumReduces Abdominal Fat and Improves Lipid Profile and Antioxidant Status in Patients with Metabolic Syndrome

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Mayara Zagonel de Souza Zanchet ◽  
Geisson Marcos Nardi ◽  
Letícia de Oliveira Souza Bratti ◽  
Fabíola Branco Filippin-Monteiro ◽  
Claudriana Locatelli
Keyword(s):  
Metabolic Syndrome ◽  
Lipid Profile ◽  
Biochemical Parameters ◽  
Antioxidant Status ◽  
Nutritional Value ◽  
Antioxidant Activities ◽  
Natural Antioxidants ◽  
Abdominal Fat ◽  
Natural Form ◽  
Goji Berry

Natural antioxidants present in fruits have attracted considerable interest due to their presumed safety and potential nutritional value. Even though antioxidant activities of many fruits have been reported, the effects of phytochemicals of goji berry (GB) in patients with metabolic syndrome have not been investigated. In this study, we examined anthropometric and biochemical parameters in patients with metabolic syndrome after the consumption of GB. The patients were divided into two groups, control (C) and supplemented (S), and followed up for 45 days. Participants were individually instructed to carry out a healthy diet, but additionally, an inclusion of 14 g of the natural form of goji berry in the diet during 45 days for the S group was proposed. After 45 days of study, a significant reduction in transaminases as well as an improvement in lipid profile in the S group was observed. Likewise, a significant reduction in the waist circumference of the S group was observed when compared with that of the C group, and increased glutathione and catalase levels associated with a reduction of lipid peroxidation. These results suggest that this is an effective dietary supplement for the prevention of cardiovascular diseases in individuals with metabolic syndrome.

scholarly journals Antioxidant Activity in Bee Products: A Review

Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 71
Author(s):  
Marianna Martinello ◽  
Franco Mutinelli
Keyword(s):  
Analytical Methods ◽  
Nutritional Value ◽  
Royal Jelly ◽  
Antioxidant Activities ◽  
Natural Antioxidants ◽  
Bioactive Substances ◽  
Current State ◽  
Wide Range ◽  
Ancient Times ◽  
Antioxidant Characteristics

Bee products have been used since ancient times both for their nutritional value and for a broad spectrum of therapeutic purposes. They are deemed to be a potential source of natural antioxidants that can counteract the effects of oxidative stress underlying the pathogenesis of many diseases. In view of the growing interest in using bioactive substances from natural sources to promote health and reduce the risk of developing certain illnesses, this review aims to update the current state of knowledge on the antioxidant capacity of bee products such as honey, pollen, propolis, beeswax, royal jelly and bee venom, and on the analytical methods used. The complex, variable composition of these products and the multitude of analytical methods used to study their antioxidant activities are responsible for the wide range of results reported by a plethora of available studies. This suggests the need to establish standardized methods to more efficiently evaluate the intrinsic antioxidant characteristics of these products and make the data obtained more comparable.

Hematologic, lipid profile, immunity, and antioxidant status of growing rabbits fed black seed as natural antioxidants

2019 ◽  
Vol 52 (3) ◽  
pp. 999-1004
Author(s):  
Yassmine El-Gindy ◽  
Hassan Zeweil ◽  
Soliman Zahran ◽  
Mohamed Abd El-Rahman ◽  
Fawzi Eisa
Keyword(s):  
Lipid Profile ◽  
Antioxidant Status ◽  
Natural Antioxidants ◽  
Black Seed

Lipid profile and plasma antioxidant status in sweet carbonated beverage-induced metabolic syndrome in rat

2011 ◽  
Vol 146 (1) ◽  
pp. 106-109 ◽  
Author(s):  
Matilde E. Otero-Losada ◽  
Daniel R. Grana ◽  
Angélica Müller ◽  
Graciela Ottaviano ◽  
Giuseppe Ambrosio ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Lipid Profile ◽  
Antioxidant Status ◽  
Carbonated Beverage ◽  
Plasma Antioxidant

scholarly journals Costus afer Protects Cardio-, Hepato-, and Reno-Antioxidant Status in Streptozotocin-Intoxicated Wistar Rats

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Armelle D. Tchamgoue ◽  
Lauve R. Y. Tchokouaha ◽  
Nole Tsabang ◽  
Protus A. Tarkang ◽  
Jules-Roger Kuiate ◽  
...  
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Antioxidant Status ◽  
Antioxidant Activities ◽  
Histopathological Examination ◽  
High Dose ◽  
Drug Induced ◽  
Normal Ranges ◽  
Hydroethanolic Extract ◽  
Costus Afer

Medicinal plants are efficient modulators of oxidative stress associated with diabetes mellitus. This study evaluated the cardio-, reno-, and hepato-antioxidant status of hydroethanolic extract of Costus afer on streptozotocin-intoxicated diabetic rats. Experimental animals were daily administered with hydroethanolic extract of C. afer by oral intubation for eight weeks (60 days), after which the levels of catalase (CAT), superoxide dismutase (SOD), glutathione (GSH), and lipid peroxidation marker (MDA) were evaluated in the heart, liver, and kidney homogenates. Plasma biochemical parameters such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), total protein, creatinine, and urea were determined. Meanwhile, parts of the heart, kidneys, and liver were histopathologically examined. Streptozotocin administration induced toxicity in the cardiac, hepatic, and renal tissues by stimulating significant increases (p<0.05) in the levels of CAT and SOD, GSH, and MDA. Similarly, significant increases (P<0.05) in the levels of ALT, AST, urea, and total protein were observed in streptozotocin treated rats, whereas decreases were observed in the levels of ALP, LDH, and creatinine. Following the treatments with C. afer hydroethanolic extract prevented the effect of streptozotocin by maintaining the tissue antioxidant status (CAT, SOD, GSH, and MDA) and the plasma biochemical parameters (AST, ALT, ALP, LDH, creatinine, and urea) towards the normal ranges. The histopathological examination revealed hepatovascular congestion and leucocyte infiltration as well as renovascular congestion, glomerulosclerosis, and tubular clarification in the untreated diabetic control and their absence in the group of animals treated with a high dose of C. afer extract. The findings of the present investigation suggest that C. afer possesses antioxidant activities capable of regulating drug induced tissue damage.

Anti-inflammatory, anti-oxidant and anti-lipaemic effects of daily dietary coenzyme-Q10 supplement in a mouse model of metabolic syndrome

2021 ◽  
Vol 20 ◽  
Author(s):  
Olakunle J. Onaolapo ◽  
Sarafa A. Omotoso ◽  
Anthony T. Olofinnade ◽  
Adejoke Y. Onaolapo
Keyword(s):  
Metabolic Syndrome ◽  
Lipid Peroxidation ◽  
Mouse Model ◽  
Lipid Profile ◽  
Antioxidant Status ◽  
Management Interventions ◽  
Tnf Α ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
The Impact

Background: The dietary model of metabolic syndrome has continued to aid our understanding of its pathogenesis and possible management interventions. However, despite progress in research, therapy continues to be challenging in humans; hence, the search for newer treatment and prevention options. Objective: To evaluate the impact of dietary CQ10 supplementation on metabolic, oxidative and inflammatory markers in a diet-induced mouse model of metabolic syndrome. Methods: Mouse groups were fed standard diet (SD), high-fat high-sugar (HFHS) diet, and SD or HFHS diet (with incorporated CQ10) at 60 and 120 mg/kg of feed respectively. At the completion of the study (8 weeks), blood glucose levels, superoxide dismutase (SOD) activity, plasma insulin, leptin, adiponectin, TNF-α, IL-10, serum lipid profile, and lipid peroxidation (LPO) levels were assessed. The liver was either homogenised for the assessment of antioxidant status or processed for general histology. Results: Dietary CQ10 mitigated HFHS diet-induced weight gain, decreased glucose, insulin and leptin levels; and increased adiponectin levels in mice. Coenzyme-Q10 improved the antioxidant status of the liver and blood in HFHS diet fed mice, while also decreasing lipid peroxidation. Lipid profile improved, level of TNF-α decreased and IL-10 increased following CQ10 diet. A mitigation of HFHS diet-induced alteration in liver morphology was also observed with CQ10. Conclusion: Dietary CQ10 supplementation mitigates HFHS diet-induced changes in mice possibly through its anti-oxidant, anti-lipaemic and anti-inflammatory potential.

Punica granatum as a Source of Natural Antioxidant and Antimicrobial Agent; a Comprehensive Review on Related Investigations

2020 ◽  
Vol 17 ◽  
Author(s):  
Atefeh Jalali ◽  
Mohammadreza Kiafar ◽  
Masih Seddigh ◽  
Mohammad M. Zarshenas
Keyword(s):  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Natural Antioxidants ◽  
Punica Granatum ◽  
Antimicrobial Activities ◽  
Natural Antioxidant ◽  
Antiviral Activities ◽  
Natural Foods

Background: The consumption of natural antioxidants is increasing due to the demand and tendency to natural foods. Punica granatum L. [Punicaceae] is a fruit with various bioactive ingredients. The effectiveness of this plant has been proved against various disorders such as hyperglycemia, hyperlipidemia, blood coagulation, infections, cancer, and dentistry. Among them, there are numerous researches on antimicrobial and antioxidant properties. Subsequently, the present study aimed to compile a review of those properties to outline this herb as a possible natural antioxidant and preservative. Methods: Synchronically, keywords "Punica granatum" with antimicrobial, or antibacterial, antifungal, antiviral, antioxidant and radical scavenging were searched through "Scopus" database up to 31st September 2019. Papers focusing on agriculture, genetics, chemistry, and environmental sciences were excluded and also related papers were collected. Results: Among 201 papers focusing on related activities, 111 papers have dealt with antioxidant activities focusing based on DPPH assay, 59 with antibacterial, on both gram+ and gram- bacteria, 24 with antifungal effects, mostly on Aspergillus niger and Candida albicans, and 7 papers with antiviral activities. There were about 50 papers focusing on in-vivo antioxidant activities of this plant. Conclusion: Taken together, botanical parts of P. granatum have possessed notable radical scavenging and antimicrobial activities that with these properties, this plant can be introduced as a natural safe source of preservative and antioxidant. Accordingly, P. granatum can be applied as excipient with the aforementioned properties in the pharmaceutical and food industries.

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