scholarly journals Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Ahmed M. Khalil ◽  
Reham A. Abdel-Monem ◽  
Osama M. Darwesh ◽  
Ahmed I. Hashim ◽  
Afaf A. Nada ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Antimicrobial Activities ◽  
Carboxymethyl Chitosan ◽  
Acidic Media ◽  
Tem Analysis ◽  
Inhibition Zones ◽  
In Situ Reactions

Schiff-bases of chitosan (CS) and carboxymethyl chitosan (CMCS)/silver nanoparticles (AgNPs) have been synthesized, characterized, and evaluated as antimicrobial agents against two Gram +ve bacteria (Bacillus cereus and Staphylococcus aureus) and two Gram −ve bacteria (Escherichia coli and Pseudomonas aeruginosa) in addition to Candida albicans as a fungus. The in situ reactions of CS and/or CMCS with some pyrazole aldehyde derivatives in acidic media containing silver nitrate to yield silver nanoparticles loaded onto CS and CMCS/Schiff-bases were carried out. Characterizations of the prepared compounds via FTIR spectroscopy, SEM, TEM, and TGA were carried out. Schiff-bases/silver nanoparticles of CS and CMCS showed higher antimicrobial activity than the blank CS and CMCS. The presence of AgNO3 (3% wt%) displayed high antibacterial efficiencies with inhibition zones in the extent of 19–39 mm. TEM analysis showed that the size of the silver nanoparticles is in the range of 4–28 nm for the prepared nanocomposites.

scholarly journals Synthesis and Evaluation of Schiff Bases of 4-Amino-5-(chlorine substituted phenyl)-4H-1,2,4-triazole-3-thione as Antimicrobial Agents

2020 ◽  
Vol 41 (1) ◽  
pp. 26-35
Author(s):  
Kishor Devkota ◽  
Govinda Pathak ◽  
Bhushan Shakya
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Triazole Ring ◽  
Antimicrobial Activities ◽  
Biologically Active ◽  
Spectral Techniques ◽  
Schiff Base Derivatives ◽  
Bacteria And Fungi ◽  
Different Strains

Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems. Schiff bases are also considered as one of the most biologically active compounds.  The aim of the present study was to synthesize new Schiff bases bearing triazole nucleus and to assess their antimicrobial activities. Four new Schiff base derivatives of 1,2,4-triazole-3-thione were synthesized by combining two different pharmacophores viz. triazole nucleus and Schiff base moiety and were characterized by spectral techniques (UV, FT-IR, and NMR). The Schiff bases were evaluated for antibacterial (Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae) and antifungal (Candida albicans) activities. The synthesized compounds exhibited good to moderate activities against different strains of bacteria and fungi tested.

scholarly journals Green synthesis of silver nanoparticles using plant extracts and their antimicrobial activities: a review of recent literature

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2804-2837
Author(s):  
Chhangte Vanlalveni ◽  
Samuel Lallianrawna ◽  
Ayushi Biswas ◽  
Manickam Selvaraj ◽  
Bishwajit Changmai ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Plant Extracts ◽  
Antimicrobial Agents ◽  
Recent Literature ◽  
Antimicrobial Activities ◽  
New Findings ◽  
Potential Applications ◽  
Research Domain

Herein, we have reviewed new findings in the research domain of the green synthesis of silver nanoparticles using different plant extracts and their potential applications as antimicrobial agents covering the literature since 2015.

scholarly journals Assessment of Antioxidant and Antimicrobial Activities of Silver Nanoparticles Biosynthesized by Haplophyllum Obtusifolium

2020 ◽  
Vol 8 (2) ◽  
pp. 94-98
Author(s):  
Mohammad Reza Rezaei ◽  
Ali Es-haghi ◽  
Parichehreh Yaghmaei ◽  
Maryam Ghobeh
Keyword(s):  
Antioxidant Activity ◽  
Silver Nanoparticles ◽  
Antimicrobial Agents ◽  
Antioxidant Activities ◽  
Antimicrobial Activities ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
The North ◽  
Chamber Temperature ◽  
Pharmaceutical Industries

Background: Plants comprise great antioxidant sources as a result of their redox and biochemical components, which are rich in secondary metabolites such as phenolic acids, flavonoids, and other constituents. Haplophyllum obtusifolium from polygonaceae is widely used for preventing and managing diabetes. This study investigated the antibacterial and antioxidant activities of silver nanoparticles (AgNPs) biosynthesized by H. obtusifolium. Methods: The aerial parts of H. obtusifolium were gathered from the north of Khorasan Razavi province, Iran and desiccated at the chamber temperature. The shoots were powdered by grinding, 5 g of the powder was mixed with 250 mL of deionized water, and the resultant blend was then filtered. Bactericidal properties and antioxidant activity of the nanoparticles were assessed using disk diffusion and DPPH (2, 2-diphenyl-1-picrylhydrazyl) tests, respectively. Results: The results of this study showed that the biosynthesized nanoparticles exhibited antibacterial activity against a gram-negative (Klebsiella pneumoniae) bacterium, but they had no effects on gram-positive Staphylococcus epidermidis. Antioxidant test results showed that these nanoparticles were capable of eliminating DPPH radicals in a concentration-dependent manner so that a more potent antioxidant activity was seen in higher concentrations of the nanoparticles. Conclusion: Our results suggested that H. obtusifolium can be used as a key source of antioxidants/ antimicrobial agents in food and pharmaceutical industries.

In Situ Synthesis of Silver Nanoparticles onto Cotton Fibers Modified with Carboxymethyl Chitosan

2020 ◽  
Vol 208 (1) ◽  
pp. 10-16
Author(s):  
Zhenming Qi ◽  
Ruizhi Zhang ◽  
Jingchun Lv ◽  
Dawei Gao ◽  
Chunxia Wang
Keyword(s):  
Silver Nanoparticles ◽  
Carboxymethyl Chitosan ◽  
In Situ Synthesis ◽  
Cotton Fibers

scholarly journals Synthesis, Structural Investigation and Antimicrobial Properties of Macrocyclic Zinc(II) Complexes with N2O2-Donor Schiff Bases Incorporating 1,2,4-Triazole Ring

2020 ◽  
Vol 32 (12) ◽  
pp. 3151-3156
Keyword(s):  
Schiff Bases ◽  
Structural Investigation ◽  
Thermal Studies ◽  
Antimicrobial Properties ◽  
Triazole Ring ◽  
Pathogenic Fungi ◽  
Elemental Analyses ◽  
Coordinated Water ◽  
In Situ Reactions

A novel series of nano-sized zinc(II) complexes of type [{Zn(M)(H2O)2}(CH3COO–)2] (where M = macrocyclic ligands) has been synthesized by the in situ reactions of Schiff bases derived from 3-(phenyl/substituted phenyl)-4-amino-5-hydrazino-1,2,4-triazoles, salicyldehyde/2-hydroxy-1- naphthaldehyde and 1,4-dibromobutane/1,5-dibromopentane in presence of zinc(II) acetate dihydrate in absolute ethanol. The structures of all these zinc(II) complexes were established on the basis of elemental analyses and spectral data (IR, 1H NMR and 13C NMR). Scanning electron microscopy studies have been carried out to investigate the particle size and surface morphology of a particular complex while thermal studies confirm the presence of coordinated water molecules in all the zinc(II) complexes. The antimicrobial effects of all the synthesized complexes were studied against different species of pathogenic fungi and bacteria.

scholarly journals Multifaceted Phytogenic Silver Nanoparticles by a Rare Insectivorous Plant Drosera Spatulata Labill Var.bakoensis and its Enhanced Antioxidant, Antibacterial, Antifungal and in Vitro Cytotoxic Studies

2021 ◽  
Author(s):  
Susmila Aparna Gaddam ◽  
Venkata Subbaiah Kotakadi ◽  
Gunasekhar. Kalavakunta ◽  
Josthna Penchalaneni ◽  
Varadarajulu Naidu Challagundla ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Radical Scavenging ◽  
Human Colon ◽  
Xrd Analysis ◽  
Antimicrobial Activities ◽  
Human Colon Cancer ◽  
Tem Analysis ◽  
Insectivorous Plant ◽  
Average Size

Abstract The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var.bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natural phytoconstituents which reduce the monovalent silver were identified by FTIR. The particle size of the Ds-AgNPs was detected by the Nanoparticle size analyzer confirms that the average size of nanoparticles was around 23 ± 2 nm. Ds-AgNPs exhibit high stability because of their high negative zeta potential (-34.1 mV). AFM studies also revealed that the Ds-AgNPs were spherical in shape and average size ranges from 10 to 20 ± 5 nm. TEM analysis also revealed that the average size of Ds-AgNPs was also around 21 ± 4 nm and the shape is roughly spherical and well dispersed. The crystal nature of Ds-AgNPs was detected as a face-centered cube by the XRD analysis. Furthermore, studies on antibacterial and antifungal activities manifested outstanding antimicrobial activities of Ds-AgNPs compared with standard antibiotic Amoxyclav. In addition, demonstration of superior free radical scavenging efficacy coupled with potential in vitro cytotoxic significance on Human colon cancer cell lines (HT-29) suggests that the Ds-AgNPs attain excellent multifunctional therapeutic applications.

Antimicrobial Activity of Myrtus communis L., Cinnamomum verum and Eugenia caryophyllata Alcoholic Mixtures

2020 ◽  
Vol 16 (2) ◽  
pp. 207-212
Author(s):  
Wissam Zam ◽  
Ali Ali ◽  
Walaa Ibrahim
Keyword(s):  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Myrtus Communis ◽  
Myrtus Communis L ◽  
Inhibition Zones ◽  
Alcoholic Mixtures

Background and Objective: With the significant increase in the prevalence of infectious diseases and the development of drug resistance by human pathogenic bacteria, there is a continuous need to discover new antimicrobial compounds from plants. Methods: Four extracts of wild Myrtus communis L. berries (myrtle berries) were prepared with the addition of Cinnamomum verum and Eugenia caryophyllata. The extracts were screened in vitro for their antimicrobial activities using agar-well diffusion method against Escherichia coli, Staphylococcus aureus, Enterobacter cloacae, Listeria monocytogenes, Pseudomonas aeruginosa and Proteus mirabilis cultures. Results: The inhibition zones ranged from 12 to 22 mm. The MICs values of extracts lies between the ranges of 30 to 100 mg/ml. Of the extracts studied, the most active ones were those obtained from the myrtle berries:cloves, myrtle berries:cinnamon:cloves with the highest inhibition zones 22 mm and 17mm against S. aureus and L. monocytogenes at 50 mg/ml and 80 mg/ml, respectively. None of the extracts was active against E. coli and P. mirabilis. Conclusion: The present investigations have exposed that the myrtle berries:cloves, myrtle berries: cinnamon:cloves extracts could be used in traditional medicine as natural antimicrobial agents in treatment the bacterial infections.

scholarly journals Characterization of Silver NanoparticleIn SituSynthesis on Porous Sericin Gel for Antibacterial Application

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Gang Tao ◽  
Lina Liu ◽  
Yejing Wang ◽  
Huaipu Chang ◽  
Ping Zhao ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Irradiation Time ◽  
Inhibition Zone ◽  
Antimicrobial Activities ◽  
Scanning Calorimetry ◽  
Structure And Property ◽  
Gram Positive Bacteria ◽  
Synthesis Approach

Sericin fromBombyx moricocoon has good hydrophilicity, reaction activity, biocompatibility, and biodegradability, which has shown great potentials for biomedical materials. Here, an ultraviolet light-assistedin situsynthesis approach is developed to immobilize silver nanoparticles on the surface of sericin gel. The amount of silver nanoparticles immobilized on the surface of sericin gel could be regulated by the irradiation time. The porous structure and property of sericin gel were not affected by the modification of AgNPs, as evidenced by the observation of scanning electron microscopy, X-ray diffractometry, and Fourier transform infrared spectroscopy. Differential scanning calorimetry analysis showed that the modification of AgNPs increased the thermal stability of sericin gel. The growth curve of bacteria and inhibition zone assays suggested that the sericin gel modified with AgNPs had good antimicrobial activities against both Gram-negative and Gram-positive bacteria. This novel sericin has shown a great potential for biomedical purpose.

scholarly journals Synthesis, Characterization and In Vitro Antibacterial Evaluation of Pyrenacantha grandiflora Conjugated Silver Nanoparticles

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1568
Author(s):  
Arinao Murei ◽  
Karen Pillay ◽  
Patrick Govender ◽  
Ntevheleni Thovhogi ◽  
Wilson M. Gitari ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antimicrobial Agents ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Biological Synthesis ◽  
Klebsiella Pneumonia ◽  
Drug Resistant ◽  
Biological Methods ◽  
Mic Value

In the present study, silver nanoparticles (AgNPs) were synthesized using both the chemical and biological methods and conjugated with Pyrenacantha grandiflora extracts. These were then characterized and evaluated for antimicrobial activities against multi-drug resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia, and Escherichia coli. Nanoparticles were analyzed with UV-visible spectrophotometer, transmission electron microscopy (TEM), and energy dispersive X-ray analysis (EDX). Silver nanoparticles, P. grandiflora extracts, and the conjugates were also analyzed with Fourier transform infrared spectroscopy (FTIR). As a result, quasi-sphere-shaped AgNPs with sizes ranging from 5 to 33 nm and spherically shaped AgNPs with sizes ranging from 3 to 25 nm were formed from chemical and biological synthesis, respectively. A well diffusion assay showed that the activity of silver nanoparticles was most improved with acetone extract against all tested bacteria with diameters in the range of 19–24 mm. The lowest MIC value of 0.0063 mg/mL against MRSA was observed when biologically synthesized AgNPs were conjugated with acetone and water extracts. Chemically synthesized silver nanoparticles showed the lowest MIC value of 0.0063 mg/mL against E. coli when conjugated with acetone and methanol extracts. This study indicates that silver nanoparticles conjugated with P. gandiflora tubers extracts exhibit strong antibacterial activities against multi-drug resistant bacterial pathogens. Therefore, biosynthesized conjugates could be utilized as antimicrobial agents for effective disease management due to the synergistic antibacterial activity that was observed.

scholarly journals Green synthesis, characterization, and antimicrobial activity of silver nanoparticles prepared using Trigonella foenum-graecum L. leaves grown in Saudi Arabia

2021 ◽  
Vol 10 (1) ◽  
pp. 421-429
Author(s):  
Humaira Rizwana ◽  
Mona S. Alwhibi ◽  
Hadeel A. Aldarsone ◽  
Manal Ahmed Awad ◽  
Dina A. Soliman ◽  
...  
Keyword(s):  
Particle Size ◽  
Silver Nanoparticles ◽  
Saudi Arabia ◽  
Green Synthesis ◽  
Antimicrobial Agents ◽  
Average Particle Size ◽  
Antimicrobial Activities ◽  
Average Particle ◽  
Pathogenic Yeast ◽  
Trigonella Foenum Graecum L

Abstract Silver nanoparticles (AgNPs) are widely used for medical applications particularly as antimicrobial agents against multidrug-resistant microbial strains. Some plants stimulate the reduction of Ag ions to AgNPs. In this study, we prepared AgNPs via the green synthesis approach using fenugreek leaves grown in Saudi Arabia. Furthermore, we characterized these AgNPs and evaluated their antimicrobial activities against pathogenic yeast, bacteria, and fungi. The ultraviolet-visible peak at 380 nm confirmed the biosynthesis of NPs. Transmission electron microscopy analyses revealed particle size in the range of 9–57 nm with a spherical shape. Dynamic light scattering results confirm slight aggregation as the average particle size was shown as 68.71 nm and a polydispersity index of 0.083. The energy-dispersive X-ray spectroscopy results showed an intense peak at 3 keV, indicating the presence of elemental AgNPs. The synthesized AgNPs efficiently inhibit the growth of both Gram-positive and Gram-negative bacteria; however, varying degree of inhibition was shown toward fungi. The potent antimicrobial ability of the synthesized NPs can be attributed to their small size and round shape. Among all test organisms, the growth of Candida albicans and Helminthosporium sativum was remarkably affected by AgNPs treatment.

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