scholarly journals A High Protein Diet Has No Harmful Effects: A One-Year Crossover Study in Resistance-Trained Males

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Jose Antonio ◽  
Anya Ellerbroek ◽  
Tobin Silver ◽  
Leonel Vargas ◽  
Armando Tamayo ◽  
...  
Keyword(s):  
Blood Lipids ◽  
High Protein Diet ◽  
Normal Diet ◽  
High Protein ◽  
Protein Diet ◽  
Bod Pod ◽  
Self Reports ◽  
Liver And Kidney ◽  
One Year ◽  
Harmful Effects

The purpose of this investigation was to determine the effects of a high protein diet over a one-year period. Fourteen healthy resistance-trained men completed the study (mean ± SD; age26.3±3.9 yr; height178.5±8.4 cm; and average years of training8.9±3.4 yr). In a randomized crossover design, subjects consumed their habitual or normal diet for 2 months and 4 months and alternated that with a higher protein diet (>3 g/kg/d) for 2 months and 4 months. Thus, on average, each subject was on their normal diet for 6 months and a higher protein diet for 6 months. Body composition was assessed via the Bod Pod®. Each subject provided approximately 100–168 daily dietary self-reports. During the subjects’ normal eating phase, they consumed (mean ± SD)29.94±5.65 kcals/kg/day and2.51±0.69 g/kg/day of protein. This significantly increased (p<0.05) during the high protein phase to34.37±5.88 kcals/kg/day and3.32±0.87 g/kg/day of protein. Our investigation discovered that, in resistance-trained men that consumed a high protein diet (~2.51–3.32 g/kg/d) for one year, there were no harmful effects on measures of blood lipids as well as liver and kidney function. In addition, despite the total increase in energy intake during the high protein phase, subjects did not experience an increase in fat mass.

scholarly journals The Effects of a High-Protein Diet on Bone Mineral Density in Exercise-Trained Women: A 1-Year Investigation

2018 ◽  
Vol 3 (4) ◽  
pp. 62
Author(s):  
Jose Antonio ◽  
Anya Ellerbroek ◽  
Cassandra Carson
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mineral ◽  
Mineral Content ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Whole Body ◽  
Mineral Density ◽  
One Year

The effects of long-term high-protein consumption (i.e., >2.2 g/kg/day) are unclear as it relates to bone mineral content. Thus, the primary endpoint of this investigation was to determine if consuming a high-protein diet for one year affected various parameters of body composition in exercise-trained women. This investigation is a follow-up to a prior 6-month study. Subjects were instructed to consume a high-protein diet (>2.2 g/kg/day) for one year. Body composition was assessed via dual-energy X-ray absorptiometry (DXA). Subjects were instructed to keep a food diary (i.e., log their food ~three days per week for a year) via the mobile app MyFitnessPal®. Furthermore, a subset of subjects had their blood analyzed (i.e., basic metabolic panel). Subjects consumed a high-protein diet for one year (mean ± SD: 2.3 ± 1.1 grams per kilogram body weight daily [g/kg/day]). There were no significant changes for any measure of body composition over the course of the year (i.e., body weight, fat mass, lean body mass, percent fat, whole body bone mineral content, whole body T-score, whole body bone mineral density, lumbar bone mineral content, lumbar bone mineral density and lumbar T-score). In addition, we found no adverse effects on kidney function. Based on this 1-year within-subjects investigation, it is evident that a diet high in protein has no adverse effects on bone mineral density or kidney function.

scholarly journals Ameliorative effects of high-protein diet on hepatotoxic alterations in Swiss albino mice exposed to mobile phone radiation

2021 ◽  
Vol 64 ◽  
pp. 258-264
Author(s):  
Debajyoti Bhattacharya ◽  
Prerona Biswas ◽  
Somnath Gangopadhyay ◽  
Mausumi Sikdar Bhakta
Keyword(s):  
Electromagnetic Radiation ◽  
Mobile Phone ◽  
Mobile Phones ◽  
High Protein Diet ◽  
Normal Diet ◽  
Exposed Group ◽  
High Protein ◽  
Protein Diet ◽  
Swiss Albino Mice ◽  
Mobile Phone Radiation

Objectives: Nowadays, mobile phones have become a prime necessity. At present, various advance networking connections such as 3G and 4G are available in the market to get a faster service. However, these mobile phones emit harmful electromagnetic radiations which have various ill effects on different physiological systems. The present study has been done to find out the extent of damage caused by mobile phone radiation on liver cells, and, whether high-protein diet (HPD) has any ameliorative effect on such changes. Materials and Methods: Male Swiss Albino mice were divided into four groups. Two groups of animals were exposed to mobile phone radiation at global system for mobile communications like frequencies at 1.8 GHz for 3 h continuously per day for 90 days. One of these radiation exposed groups received a normal diet (containing 5% casein) and the other exposed group received a HPD (supplemented with 20% casein). The control group animals received only a normal diet, while the animals of the remaining group received only a HPD. The serum biochemical and histological parameters of liver tissues and ladder assay of hepatic DNA were studied. Results: A significantly elevated level (P < 0.05) of aspartate aminotransferase, alanine transaminase, bilirubin and serum caspase-3 levels was observed in the group of animals exposed to electromagnetic radiation emitted from mobile phone. Histological changes were also observed in the experimental groups. Moreover, in genomic DNA ladder assay, fragmented DNA was observed in exposed group, which is a probable sign of cell apoptosis. Recovery symptoms were observed in the animals supplemented with high casein diet. Conclusion: From the present study, it may be concluded that electromagnetic radiation emitted from mobile phones has damaging effects on hepatocytes which may be ameliorated by HPD.

scholarly journals EFFECT OF HIGH PROTEIN DIET IN ACTIVITY OF ANTIOXIDANTS AND LEVEL OF INFLAMMATION ON SPRINT ATHLETE

2021 ◽  
Author(s):  
Endang Sri Wahjunia ◽  
Soetanto Hartono
Keyword(s):  
High Protein Diet ◽  
Normal Diet ◽  
High Protein ◽  
Protein Diet ◽  
Control Group ◽  
Multivariate Technique ◽  
Tnf Α ◽  
Low Carbohydrate ◽  
Photo Camera ◽  
Laboratory Examinations

This study aims to analyze the effect of a low-carbohydrate high-protein diet to increase the level of antioxidant, decrease inflammation and improve performance of athlete. The research was carried out by experimental research methods, within the design of "Randomized Control Group Pretest Posttest Design".A sample was taken from 20 people who met the inclusion and exclusion criteria from 30 teenage athletes in PASI East Java sprints. The Data were collected by measuring the sprint results by finish photo camera and laboratory examinations to determine the levels of antioxidants (SOD) and the inflammation degree (TNF α)in blood. The data were analyzed using multivariate technique (Manova) Hotelling's method (T2). Hypothesis testing using α0.05. The results and conclusions of the study stated that the normal diet had no effect on the variables of sprint running speed, SOD and TNF-α levels. While low-carbohydrate and high-protein diet can increase SOD levels of 211.44 /gHb, reduce (TNF α) at least 0.309 pg/ml, and the average increase in antioxidant activity caused by low-carbohydrate-high-protein diet is 24,989 / gHb higher than normal diet, the decrease in the degree of inflammation is 0.196 pg/ml, however, it has no effect on the speed of sprint.

scholarly journals Effect of high protein diet in activity of antioxidants and level of inflammation on sprint athlete

2021 ◽  
Vol 57 (2) ◽  
pp. 185-194
Author(s):  
Endang Sri Wahjuni ◽  
Soetanto Hartono
Keyword(s):  
High Protein Diet ◽  
Normal Diet ◽  
High Protein ◽  
Protein Diet ◽  
Control Group ◽  
Multivariate Technique ◽  
Tnf Α ◽  
Low Carbohydrate ◽  
Photo Camera ◽  
Laboratory Examinations

This study aims to analyze the effect of a low-carbohydrate high-protein diet to increase the level of antioxidant, decrease inflammation and improve performance of athlete. The research was carried out by experimental research methods, within the design of “Randomized Control Group Pretest Posttest Design”. A sample was taken from 20 people who met the inclusion and exclusion criteria from 30 teenage athletes in PASI East Java sprints. The Data were collected by measuring the sprint results by finish photo camera and laboratory examinations to determine the levels of antioxidants (SOD) and the inflammation degree (TNF-α) in blood. The data were analyzed using multivariate technique (Manova) Hotelling’s method (T2). Hypothesis testing using α = 0.05. The results and conclusions of the study stated that the normal diet had no effect on the variables of sprint running speed, SOD and TNF-α levels. While low-carbohydrate and high-protein diet can increase SOD levels of 211.44/gHb, reduce (TNF-α) at least 0.309 pg/ml, and the average increase in antioxidant activity caused by low-carbohydrate-high-protein diet is 24.989/gHb higher than normal diet, the decrease in the degree of inflammation is 0.196 pg/ml, however, it has no effect on the speed of sprint.

Copper supplementation of pig diets. The effect of protein level and zinc supplementation on the response to added copper

1968 ◽  
Vol 10 (4) ◽  
pp. 423-432 ◽  
Author(s):  
T. J. Hanrahan ◽  
J. F. O'Grady
Keyword(s):  
Protein Level ◽  
Copper Sulphate ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Copper Toxicosis ◽  
Low Protein ◽  
Copper And Zinc ◽  
Copper Supplementation ◽  
Liver And Kidney

1. Five hundred and fifty-two pigs were used in an experiment having six treatments. High and low protein rations were given (a) unsupplemented, (b) supplemented with 0·1% copper sulphate (CuSO4·5H2O) and (c) supplemented with 0·1% copper sulphate and 0·025% zinc carbonate (ZnCO3).2. Performance was significantly reduced and 18 pigs died from copper toxicosis, when the low protein ration supplemented with copper sulphate was fed.3. There were no indications of toxicity and performance was equal to the controls when the low protein diet supplemented with copper and zinc was fed.4. The addition of copper to the high protein diet slightly reduced performance and six pigs died from copper toxicosis.5. The addition of copper and zinc to the high protein diet improved growth rate and eliminated the toxicity associated with copper supplementation.6. No significant treatment effects on haemoglobin or packed cell volume were observed, other than a small effect of protein level on PCV.7. Copper supplementation of the diets significantly increased liver and kidney copper levels and liver zinc levels. It reduced liver and kidney iron contents. The addition of copper and zinc to the diet reduced the increase in liver copper associated with copper supplementation, and increased the level of zinc in both livers and kidneys.

High Protein Diet and Phenylalanine Hydroxylase Activities in Rats

Pteridines ◽  
1989 ◽  
Vol 1 (4) ◽  
pp. 235-238 ◽  
Author(s):  
Michael P. Carty ◽  
Edel Beirne ◽  
John Donlon
Keyword(s):  
Rat Liver ◽  
Phenylalanine Hydroxylase ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Casein Diet ◽  
Dependent Activity ◽  
Liver And Kidney ◽  
Phenylalanine Metabolism

SummaryThe effects of a diet of 85% casein on the activities of the phenylalanine hydroxylases of rat liver and kidney have been compared. Whereas only the tetrahydrobiopterin-dependent activity of rat hepatic phenylalanine hydroxylase is significantly stimulated, both the tetrahydrobiopterin-dependent and the dimethyltetrahydropterin- dependent activities of the renal enzyme are significantly decreased, after five days of feeding a casein diet. The animals fed a high protein diet for seven days have an increased rate of phenylalanine catabolism in vivo, which is also reflected in increased flux of label from phenylalanine into glucose. The regulation of phenylalanine metabolism, under these conditions, is discussed.

Dietary protein does not alter intrinsic reactivity of renal microcirculation to angiotensin II in rodents

1995 ◽  
Vol 268 (2) ◽  
pp. F302-F308 ◽  
Author(s):  
S. R. Inman ◽  
N. T. Stowe ◽  
J. V. Nally ◽  
B. H. Brouhard ◽  
D. G. Vidt
Keyword(s):  
Angiotensin Ii ◽  
Dietary Protein ◽  
Vascular Reactivity ◽  
High Protein Diet ◽  
Normal Diet ◽  
High Protein ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Renal Microcirculation ◽  
Low Protein

The effect of dietary protein on renal function and on renal microvascular reactivity to angiotensin II was determined in rats fed a high-protein diet (40% protein), a low-protein diet (6% protein), or a normal diet (23% protein). Inulin clearance was higher in high-protein-fed rats (n = 7) than in rats fed a low-protein diet (n = 7), 0.88 +/- 0.14 (means +/- SE) vs. 0.54 +/- 0.07 ml.min-1.g kidney wt-1 (P < 0.05). We also used videomicroscopy to assess the effect of angiotensin II on the renal microcirculation in a hydronephrotic kidney preparation. The afferent and efferent arterioles constricted to angiotensin II and norepinephrine in both high- and low-protein-fed rats; this constriction was diminished to angiotensin II but not to norepinephrine, in rats fed a high-protein diet (-24.3 +/- 4.5, -20.2 +/- 4.2%) compared with rats fed a low-protein diet (-39 +/- 5.1, -39.1 +/- 5.7%). The vasoconstrictor responses to angiotensin II in rats fed a high-protein diet and a normal diet were significantly greater following inhibition of angiotensin II formation with captopril but not in low-protein-fed rats. The apparent high-endogenous level of angiotensin II among rats fed a high-protein diet may account for the diminished reactivity to exogenous angiotensin II. Thus alterations in intrinsic vascular reactivity to angiotensin II are not responsible for the altered hemodynamics associated with dietary protein.

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