scholarly journals Coexisting Situs Inversus Totalis and Immune Thrombocytopenic Purpura

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Kemal Gundogdu ◽  
Fatih Altintoprak ◽  
Mustafa Yener Uzunoğlu ◽  
Enis Dikicier ◽  
İsmail Zengin ◽  
...  
Keyword(s):  
Autoimmune Disease ◽  
Surgical Approach ◽  
Situs Inversus ◽  
Immune Thrombocytopenic Purpura ◽  
Mirror Symmetry ◽  
Congenital Abnormality ◽  
Situs Inversus Totalis ◽  
Thrombocytopenic Purpura ◽  
Abdominal Organs ◽  
Rare Congenital Abnormality

Situs inversus totalis is a rare congenital abnormality with mirror symmetry of mediastinal and abdominal organs. Immune thrombocytopenic purpura is an autoimmune disease with destruction of thrombocytes. This paper is presentation of surgical approach to a case with coexistence of these two conditions.

scholarly journals Surgical Repair of a Unileaflet Mitral Valve: A Rare Congenital Abnormality and a Novel Surgical Approach

CASE ◽  
2020 ◽  
Vol 4 (5) ◽  
pp. 420-428
Author(s):  
Kisoth Arasaratnam ◽  
Stephen Tomlinson ◽  
Arun Dahiya ◽  
Ada Lo ◽  
Homyaoun Jalali ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Surgical Approach ◽  
Congenital Abnormality ◽  
Surgical Repair ◽  
Rare Congenital Abnormality

scholarly journals Three-Port Laparoscopic Cholecystectomy in a Brazilian Amazon Woman with Situs Inversus Totalis: Surgical Approach

2008 ◽  
Vol 2 (2) ◽  
pp. 170-174 ◽  
Author(s):  
Mauro Neiva Fernandes ◽  
Ivan Nazareno Campos Neiva ◽  
Francisco de Assis Camacho ◽  
Lucas Crociati Meguins ◽  
Marcelo Neiva Fernandes ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Surgical Approach ◽  
Situs Inversus ◽  
Brazilian Amazon ◽  
Situs Inversus Totalis

scholarly journals Laparoscopic Cholecystectomy for Severe Acute Cholecystitis in a Patient with Situs Inversus Totalis and Posterior Cystic Artery

2008 ◽  
Vol 2008 ◽  
pp. 1-3 ◽  
Author(s):  
Theodoros E. Pavlidis ◽  
Kyriakos Psarras ◽  
Apostolos Triantafyllou ◽  
Georgios N. Marakis ◽  
Athanasios K. Sakantamis
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Acute Cholecystitis ◽  
Situs Inversus ◽  
Anatomical Variations ◽  
Situs Inversus Totalis ◽  
Mirror Image ◽  
Cystic Artery ◽  
Quadrant Pain ◽  
Abdominal Organs ◽  
Thoracic And Abdominal

Situs inversus totalis is an inherited condition characterized by a mirror-image transposition of thoracic and abdominal organs. It often coexists with other anatomical variations. Transposition of the organs imposes special demands on the diagnostic and surgical skills of the surgeon. We report a case of a 34-year-old female patient presented with left upper quadrant pain, signs of acute abdomen, and unknown situs inversus totalis. Severe acute cholecystitis was diagnosed, and an uneventful laparoscopic cholecystectomy was performed. A posterior cystic artery was identified and ligated. Laparoscopic cholecystectomy is feasible in patients with severe acute calculus cholecystitis and situs inversus totalis; however, the surgeon should be alert of possible anatomic variations.

scholarly journals Safety and Efficacy of Azathioprine as a Second Line Therapy for Primary Immune Thrombocytopenic Purpura

2016 ◽  
Vol 55 (203) ◽  
pp. 16-21 ◽  
Author(s):  
Bishesh Sharma Poudyal ◽  
Binaya Sapkota ◽  
Gentle Sunder Shrestha ◽  
Sujan Thapalia ◽  
Bishal Gyawali ◽  
...  
Keyword(s):  
Autoimmune Disease ◽  
Low Income ◽  
Immune Thrombocytopenic Purpura ◽  
P Value ◽  
Solid Organ ◽  
Second Line ◽  
Thrombocytopenic Purpura ◽  
Azathioprine Therapy ◽  
Platelet Counts ◽  
Steroid Refractory

Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily available and well tolerated medicine. This study was carried out to evaluate efficacy and safety of azathioprine as a second line medicine for primary ITP patients who were refractory to steroid therapy.Methods: The observational, pre-post study was conducted at Government of Nepal Civil Service Hospital, Kathmandu from January to October 2014. Twenty four primary ITP patients who were steroid refractory were treated with Azathioprine. Patients were termed steroid refractory if platelet counts were less than 30,000/ul on day 21st of steroid therapy. From day 22 onwards oral azathioprine 2mg/kg was started and steroids were tapered 10mg/week and stopped. Platelet counts of more than 30000/ul after one month of stopping steroid, while still on azathioprine, were termed response to azathioprine. Platelet count of more than 100,000/ul was termed complete response. The associations among age, gender, duration and platelets counts were analyzed by chi square test and Fisher's exact test (when individual cell frequency was less than 5). The comparison of platelets counts among the start and day 90 of Azathioprine therapy was performed by the paired t-test. Results: The study showed that there was not significant association among age and gender of the patients and their platelets count on the start of Azathioprine therapy (p value 0.354 and 0.725 respectively) and on day 90 of Azathioprine therapy (p value 0.082 and 0.762 respectively). The duration-wise comparisons of platelets count on both the start and day 90 of Azathioprine therapy were significant (p values 0.029 and 0.008 respectively). The paired comparison among platelets count on the start and day 90 of Azathioprine therapy was highly significant (p value 0.000).Conclusions: The study showed the therapeutic implication of azathioprine in ITP patients. It also showed that efficacy of azathioprine was comparable with other modes of treatment. In low income countries like Nepal azathioprine can be considered as second line treatment for steroid refractory ITP patients.Keywords: Immune thrombocytopenic purpura; autoimmune disease; steroids; azathioprine; Nepal. | PubMed

scholarly journals Laparoscopic Cholecystectomy in Kartagener Syndrome

2017 ◽  
Vol 51 (4) ◽  
pp. 192-194
Author(s):  
Rahul Gupta ◽  
Harjeet Singh ◽  
Ganga R Verma
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Laparoscopic Surgery ◽  
Magnetic Resonance ◽  
Situs Inversus ◽  
Autosomal Recessive ◽  
Epigastric Pain ◽  
Autosomal Recessive Disorder ◽  
Situs Inversus Totalis ◽  
Kartagener Syndrome ◽  
Abdominal Organs

ABSTRACT Kartagener syndrome is a rare autosomal recessive disorder in which there is situs inversus involving abdominal or thoracic viscera or both. Anatomy of the abdominal organs in such a patient is distorted making laparoscopic surgery very difficult. A 45-year-old lady, a known case of Kartagener syndrome, presented with epigastric pain. Ultrasound of abdomen revealed situs inversus with mild hepatomegaly and multiple gallbladder calculi. Magnetic resonance pancreatocholangiography (MRCP) confirmed situs inversus totalis with cholelithiasis and mild central intrahepatic biliary dilatation. Patient was treated successfully with laparoscopic cholecystectomy. How to cite this article Gupta R, Singh H, Verma GR. Laparoscopic Cholecystectomy in Kartagener Syndrome. J Postgrad Med Edu Res 2017;51(4):192-194.

scholarly journals Living donor hand-assisted laparoscopic nephrectomy in a healthy individual with situs inversus totalis: no need to turn down the donor

2020 ◽  
Vol 13 (1) ◽  
pp. e233523
Author(s):  
Stan Benjamens ◽  
Tamar Alice Johanne van den Berg ◽  
Johan Frédéric Michel Lange ◽  
Robert Alexander Pol
Keyword(s):  
Situs Inversus ◽  
Living Donor ◽  
Sagittal Plane ◽  
High Volume ◽  
Situs Inversus Totalis ◽  
Laparoscopic Nephrectomy ◽  
Close Relative ◽  
Living Kidney Donors ◽  
Abdominal Organs ◽  
Thoracic And Abdominal

A 70-year-old healthy male individual offered to undergo a living donor hand-assisted laparoscopic nephrectomy to enable kidney transplantation for a close relative. As required for all living transplant donor candidates, extensive screening was performed to exclude potential contraindications for donation. Tests revealed a situs inversus totalis, meaning a complete transposition of the thoracic and abdominal organs in the sagittal plane. As other contraindications for living kidney donation were absent, the feasibility of this procedure was determined multidisciplinary. A successful donation procedure was performed without surgical complications for the donor and good short-term transplant outcomes. In line with current developments that have resulted in more liberal criteria for potential living kidney donors, major anatomical deviations should not automatically be a contraindication. With multidisciplinary efforts and thorough surgical preparation at a high-volume transplant centre, this procedure is feasible and safe.

scholarly journals Minimally invasive esophagectomy with intrathoracic anastomosis in a situs inversus totalis patient

2020 ◽  
Vol 2020 (11) ◽  
Author(s):  
Yunchong Meng ◽  
Han Xiao ◽  
Zheng Zhang ◽  
Kuo Li ◽  
Quanfu Huang ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Situs Inversus ◽  
Minimally Invasive Esophagectomy ◽  
Rare Condition ◽  
Situs Inversus Totalis ◽  
Intrathoracic Anastomosis ◽  
Invasive Esophagectomy ◽  
Abdominal Organs ◽  
Congenital Condition ◽  
Thoracic And Abdominal

Abstract Situs inversus totalis (SIT) is a rare congenital condition, which is characterized by abnormal placement of the thoracic and abdominal organs. The incidence of this condition is estimated to be from 1/8000 to 1/25,000. There have been minimal reports on SIT patients with esophageal cancer. In this report, we discuss a patient with SIT complicated by middle and lower esophageal cancer who underwent laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis, and provide useful information with regards to treatment of this rare condition.

scholarly journals Laparoscopic simple nephrectomy patient wıth situs inversus totalis and left renal hypoplasia: A case report

2015 ◽  
Vol 9 (7-8) ◽  
pp. 521 ◽  
Author(s):  
Haci Ibrahim Cimen ◽  
Yavuz Tarik Atik ◽  
Oztug Adsan
Keyword(s):  
Case Report ◽  
Situs Inversus ◽  
Situs Inversus Totalis ◽  
Renal Hypoplasia ◽  
Normal Side ◽  
Laparoscopic Procedures ◽  
Abdominal Organs ◽  
Opposite Position ◽  
Thoracic And Abdominal

Situs inversus totalis (SIT) is a relatively rare anatomical condition characterized by the transposition of thoracic and abdominal organs from the normal side to the opposite position. Most reports of laparoscopic procedures in patients with SIT cite technical difficulties and longer operative times due to disorientation because of the reversed abdominal organs and necessary modification of the surgeon’s movements and techniques. We present a case of a patient with SIT in whom a transperitoneal laparoscopic simple nephrectomy was performed.

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