scholarly journals Nitric Oxide Concentration and Other Salivary Changes after Insertion of New Complete Dentures in Edentulous Subjects

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Maria de Lourdes Breseghelo ◽  
Lídia Andreu Guillo ◽  
Túlio Eduardo Nogueira ◽  
Cláudio Rodrigues Leles

Objective. To assess changes in levels of salivary nitric oxide (NO) after insertion of new complete dentures and its association with clinical and salivary parameters.Methods. Nineteen fully edentulous subjects were included, mean age 64.4. Unstimulated whole saliva was collected before and after insertion of the dentures, at follow-up visits, and after 12 months. The concentration of the final stable NO product (nitrite) was measured by a colorimetric assay based on the Griess reaction. Clinical parameters were assessed during all clinical visits.Results. Functional adaptation to the dentures progressively improved, with no complaints at the long-term follow-up. NO concentration was not influenced by the level of functional adaptation, presence of injuries to the mucosa, salivary flow, and saliva viscosity. Pairwise comparison showed a reduction in NO concentration at the first follow-up compared to baseline values but differences were not statistically significant. Significant differences were observed in NO concentrations at the long-term follow-up when compared to the first (p=0.024) and second (p=0.027) visits.Conclusion. NO concentration reduced after denture insertion and returned to baseline levels in the long-term follow-up. This appears to be an autonomic response of the body and provides valuable complementary information for the management of the edentulous patient.

2016 ◽  
Vol 88 (4) ◽  
pp. 249 ◽  
Author(s):  
Kemal Sarica ◽  
Fatma Narter ◽  
Kubilay Sabuncu ◽  
Ahmet Akca ◽  
Utku Can ◽  
...  

Objective: To investigate the possible effects of dietary, patient and stone related factors on the clinical course of the stone disease as well as the body and renal growth status of the infants. Patients and Methods: A total of 50 children with an history of stone disease during infancy period were studied. Patient (anatomical abnormalities, urinary tract infection - UTI, associated morbidities), stone (obstruction, UTI and required interventions) and lastly dietary (duration of sole breast feeding, formula feeding) related factors which may affect the clinical course of the disease were all evaluated for their effects on the body and renal growth during long-term follow-up. Results: Mean age of the children was 2.40 ± 2.65 years. Our findings demonstrated that infants receiving longer period of breast feeding without formula addition seemed to have a higher rate of normal growth percentile values when compared with the other children. Again, higher frequency of UTI and stone attacks affected the growth status of the infants in a remarkable manner than the other cases. Our findings also demonstrated that thorough a close follow-up and appropriately taken measures; the possible growth retardation as well as renal growth problems could be avoided in children beginning to suffer from stone disease during infancy period. Conclusions: Duration of breast feeding, frequency of UTI, number of stone attacks and stone removal procedures are crucial factors for the clinical course of stone disease in infants that may affect the body as well as kidney growth during long-term follow-up.


1996 ◽  
Vol 1 (5) ◽  
pp. E4
Author(s):  
Paul M. Kanev ◽  
Catherine M. Foley ◽  
Dan Miles

Functional hemispherectomy techniques have been designed to minimize the long-term complications of anatomical resection without reducing the effectiveness of seizure control. The authors have used an ultrasound-guided approach tailored to combine temporal lobectomy with frontal and occipital disconnections with a central topectomy of the lateral, insular, and interhemispheric cortex. This technique achieves a comprehensive functional disconnection and minimizes entrance and manipulation within the body of the lateral ventricle. Eight patients ranging in age from 10 months to 23 years with congenital paresis and medically intractable seizures underwent functional hemispherectomy via this technique. The average surgical time was 4.5 hours, and blood loss ranged from 90 to 400 ml. All but one patient was discharged after 5 days. Postoperative fever syndromes, aseptic meningitis, and infection were avoided. On long-term follow-up evaluation (range l8-60 months, mean 38 months), seven of eight patients remain seizure free and were not on a course of anticonvulsant agents. Advantages of this technique include avoiding entrance within the ventricle, a more predictable postoperative period, and reduced postoperative complications.


2020 ◽  
Vol 33 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Zhilei Zhang ◽  
Yanyun Wang ◽  
Dingyuan Ma ◽  
Wei Cheng ◽  
Yun Sun ◽  
...  

AbstractBackgroundHypermethioninemia is a group of diseases with elevated plasma methionine (Met) caused by hereditary and non-hereditary factors, although it could also be caused by administration of the amino acid Met. Among these, the disease caused by methionine adenosyltransferase (MAT) I/III deficiency is the most common, and is characterized by persistent, isolated hypermethioninemia as well as slightly elevated homocysteine. S-adenosylmethionine is the product of Met, which can be used as a direct methyl donor of many substances, such as choline and nucleotide, and essential in the development of the body. Among the patients, most have no symptoms, and a small number have central nervous system complications with high levels of plasma Met, including mental retardation, cognitive impairment and special breathing odor.MethodsIn this study, five cases of MAT I/III deficiency were diagnosed and retrospectively analyzed among 220,000 newborns. Patients with high Met levels received a Met-restricted diet treatment. Results and conclusionsMAT I/III deficiency is a common reason for Met elevation in neonatal screening by tandem mass spectrometry (MS/MS), which needs long-term follow-up except for these patients with explicitly benign mutations.


2018 ◽  
Vol 22 (4) ◽  
pp. 102-107 ◽  
Author(s):  
K. A. Vishnevsky ◽  
A. Sh. Rumyantsev ◽  
N. Yu. Korosteleva

The article reflects modern ideas about the causes and mechanisms of the physical functioning disorders in patients with chronic kidney  disease receiving program hemodialysis. Various types of physical  activity are considered and the rationale for their use in dialysis  patients is justified. The diagnostics possibilities of the protein- energy deficiency main variants are presented. Possible directions  for their correction are outlined. The possibilities and methods of  regular physical training in such a complex cohort of patients with  changes in almost all the basic systems of the body are described in  detail. For patients who cannot perform physical exercises in a  training mode, a new rehabilitation technique was developed and  tested on a representative sample, and a new rehabilitation  technique that was not previously used in nephrology – a cutaneous  bilateral electrostimulation of the muscles of the lower extremities –  was justified and considered in detail. The authors give their own data on long-term follow-up of patients, which confirm the  possibilities of the presented methods not only in terms of improving physical performance, but also in improving the adequacy  of dialysis and the quality of life.


2012 ◽  
Vol 21 (3) ◽  
pp. 224-229 ◽  
Author(s):  
Candida Geerdens ◽  
Johan Vanderlinden ◽  
Guido Pieters ◽  
Amber De Herdt ◽  
Michel Probst

Author(s):  
Manu S. Sharma ◽  
Ives Cavalcante Passos ◽  
André F. Carvalho

Adverse effects are an unavoidable risk of medication treatment. Clinical trials alone do not adequately assess the entire side effect profile, and it is important to pay attention to post-marketing surveillance and long-term follow up studies. Psychotropic medications are responsible for a wide variety of adverse effects, which can affect almost any part/system of the body. Adverse effects can vary from mild nausea and vomiting to life-threatening blood dyscrasias and arrhythmias. A high number of adverse effects are associated with the action of the psychotropic medications on their primary targets outside the brain, and the additional action on the autonomic nervous system. In order to minimize the risk of adverse effects most psychotropic medications should be started with low-dose trials followed by slow titration. Care should be taken to look for drug-drug interactions and pre-existing medical and metabolic conditions which may pre-dispose a patient to certain adverse effects.


Vascular ◽  
2013 ◽  
Vol 21 (4) ◽  
pp. 261-265 ◽  
Author(s):  
M Al-Natour ◽  
A Renno ◽  
M El-Fedaly ◽  
J Abbas ◽  
M Nazzal

Stents are commonly used as a tool for revascularization of different vascular beds in the body. However, many pitfalls have been reported with their use, such as thrombosis, migration, restenosis or fractures. The latter have been strongly correlated to in-stent restenosis with long-term follow-up. We report a rare case of an early stent fracture in the brachiocephalic trunk with in-stent restenosis and recurrence of symptoms. To our knowledge there has been only one case report of a delayed brachiocephalic stent fracture in the English literature. We believe that our case is the first report of an early stent fracture in the brachiocephalic trunk.


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