scholarly journals Pharmacological Relaxation of the Ureter When Using Ureteral Access Sheaths during Ureterorenoscopy: A Randomized Feasibility Study in a Porcine Model

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Søren Kissow Lildal ◽  
Kim Hovgaard Andreassen ◽  
Frederikke Eichner Christiansen ◽  
Helene Jung ◽  
Malene Roland Pedersen ◽  
...  
Keyword(s):  
Success Rate ◽  
Feasibility Study ◽  
Classification System ◽  
Porcine Model ◽  
Muscle Tone ◽  
Saline Group ◽  
The Other ◽  
Intraluminal Pressure ◽  
Irrigation Fluid ◽  
Intrarenal Pressure

Objective. High intraluminal pressure during ureterorenoscopy (URS) increases risk of infectious and haemorrhagic complications. Intrarenal pressure may be reduced by the use of ureteral access sheaths (UASs), which on the other hand may cause ureteral damage. We have previously shown that the β-agonist isoproterenol (ISO), when administered topically in the irrigation fluid, is able to inhibit ureteral muscle tone and lower intrarenal pressure during URS. The aim of this study was to examine the effect of ISO on the success rate of UAS insertion in a porcine model. Materials and Methods. 22 pigs in which a UAS could not initially be placed were randomized to endoluminal irrigation with either ISO (0.1 μg/mL) or saline before a new insertion trial. Subsequently, it was registered whether the UAS could be passed without resistance. During extraction of the sheath, any ureteral lesions were characterized ureteroscopically using the PULS classification system. Surgeons were blinded to randomization. Results. In the ISO group, the observed effect of irrigation was 63% successful UAS insertions, compared to 27% in the saline group. No serious lesions (<PULS grade 2) were observed in the ISO group. Conclusions. Endoluminal irrigation with ISO may facilitate UAS insertion and potentially decrease UAS related ureteral lesions.

scholarly journals Determinants of valve gating in collecting lymphatic vessels from rat mesentery

2011 ◽  
Vol 301 (1) ◽  
pp. H48-H60 ◽  
Author(s):  
Michael J. Davis ◽  
Elaheh Rahbar ◽  
Anatoliy A. Gashev ◽  
David C. Zawieja ◽  
James E. Moore
Keyword(s):  
Pressure Gradient ◽  
Muscle Tone ◽  
Lymphatic Vessels ◽  
Vessel Diameter ◽  
Intraluminal Pressure ◽  
Pressure Gradients ◽  
Rat Mesentery ◽  
Temporal Relationships ◽  
Wide Range ◽  
Valve Opening

Secondary lymphatic valves are essential for minimizing backflow of lymph and are presumed to gate passively according to the instantaneous trans-valve pressure gradient. We hypothesized that valve gating is also modulated by vessel distention, which could alter leaflet stiffness and coaptation. To test this hypothesis, we devised protocols to measure the small pressure gradients required to open or close lymphatic valves and determine if the gradients varied as a function of vessel diameter. Lymphatic vessels were isolated from rat mesentery, cannulated, and pressurized using a servo-control system. Detection of valve leaflet position simultaneously with diameter and intraluminal pressure changes in two-valve segments revealed the detailed temporal relationships between these parameters during the lymphatic contraction cycle. The timing of valve movements was similar to that of cardiac valves, but only when lymphatic vessel afterload was elevated. The pressure gradients required to open or close a valve were determined in one-valve segments during slow, ramp-wise pressure elevation, either from the input or output side of the valve. Tests were conducted over a wide range of baseline pressures (and thus diameters) in passive vessels as well as in vessels with two levels of imposed tone. Surprisingly, the pressure gradient required for valve closure varied >20-fold (0.1–2.2 cmH2O) as a passive vessel progressively distended. Similarly, the pressure gradient required for valve opening varied sixfold with vessel distention. Finally, our functional evidence supports the concept that lymphatic muscle tone exerts an indirect effect on valve gating.

Effects of pharyngeal lubrication on the opening of obstructed upper airway

1992 ◽  
Vol 72 (6) ◽  
pp. 2311-2316 ◽  
Author(s):  
H. Miki ◽  
W. Hida ◽  
Y. Kikuchi ◽  
T. Chonan ◽  
M. Satoh ◽  
...  
Keyword(s):  
Hypoglossal Nerve ◽  
Muscle Tone ◽  
Upper Airway ◽  
Intraluminal Pressure ◽  
Lower Airway ◽  
Before And After ◽  
Airway Opening ◽  
Cervical Trachea ◽  
Artificial Surfactant ◽  
Stimulation Of

We examined the effect of electrical stimulation of the hypoglossal nerve and pharyngeal lubrication with artificial surfactant (Surfactant T-A) on the opening of obstructed upper airway in nine anesthetized supine dogs. The upper airway was isolated from the lower airway by transecting the cervical trachea. Upper airway obstruction was induced by applying constant negative pressures (5, 10, 20, and 30 cmH2O) on the rostral cut end of the trachea. Peripheral cut ends of the hypoglossal nerves were electrically stimulated by square-wave pulses at various frequencies from 10 to 30 Hz (0.2-ms duration, 5–7 V), and the critical stimulating frequency necessary for opening the obstructed upper airway was measured at each driving pressure before and after pharyngeal lubrication with artificial surfactant. The critical stimulation frequency for upper airway opening significantly increased as upper airway pressure became more negative and significantly decreased with lubrication of the upper airway. These findings suggest that greater muscle tone of the genioglossus is needed to open the occluded upper airway with larger negative intraluminal pressure and that lubrication of the pharyngeal mucosa with artificial surfactant facilitates reopening of the upper airway.

Intraarterial indocyanine green (ICG) fluorescence augmentation by marking embryonal resection areas in colorectal surgery: a feasibility study in a porcine model

2018 ◽  
Vol 28 (6) ◽  
pp. 321-325 ◽  
Author(s):  
Christian Heiliger ◽  
Jerzy Piecuch ◽  
Alexander Frank ◽  
Dorian Andrade ◽  
Viktor Von Ehrlich-Treuenstätt ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Indocyanine Green ◽  
Feasibility Study ◽  
Porcine Model

scholarly journals SOSIALISASI TEMPE SEBAGAI MAKANAN ORGANIK DAN SEHAT KEPADA IBU RUMAH TANGGA DI KOTA TANGERANG SELATAN

2018 ◽  
Vol 2 (2) ◽  
pp. 92-103
Author(s):  
Anastasi Tatik Hartanti ◽  
Yasinta Ratna Esti Wulandari ◽  
Rory Anthony Hutagalung ◽  
Tati Barus
Keyword(s):  
Success Rate ◽  
Community Service ◽  
Food Processing ◽  
Healthy Food ◽  
The Other ◽  
Survey Method ◽  
Community Knowledge ◽  
Survey Results ◽  
Strongly Agree

Tempeh is a traditional Indonesian food that has many advantages as food and the process of making it is quite simple. However, the community knowledge about tempeh and the skills to produce healthy tempeh are still low. This community service aimed to increase the knowledge about tempeh and to improve the skills of its manufacturers in making healthy and good quality tempeh. The activities were carried out for mothers living in Villa Dago Tol complex, Ciputat, South Tangerang 15414, by using the methods of counseling, demonstration, and mentoring. Monitoring was conducted to measure the success rate of participants in producing healthy tempeh. The level of community knowledge about tempeh was evaluated through survey method. The results of counseling, demonstration, and mentoring succeeded in improving the participant skills as seen from the participants' success in following the healthy tempeh-making procedure. The results were also reinforced by the results of monitoring where all participants managed to create healthy tempeh. Survey results showed participants’ increasing knowledge of healthy tempeh and motivation in producing healthy tempeh. Assessment of participants showed good results, especially in improving knowledge (73% stated strongly agree and the rest agree). The ability of the facilitators in delivering the material was also considered good by the participants (92% stated strongly agree and the rest agree). As a follow-up, the participants suggested that the training be extended to the other communities and the training also include a variety of topics such as the manufacturing of tofu, healthy food processing, sewing, and many others.

scholarly journals The Genetic Speciation of Archaeological Fish Bone: A Feasibility Study from Southeast Queensland

2002 ◽  
Vol 13 ◽  
pp. 71 ◽  
Author(s):  
Vojtech Hlinka ◽  
Sean Ulm ◽  
Tom Loy ◽  
Jay Hall
Keyword(s):  
Success Rate ◽  
Feasibility Study ◽  
Late Holocene ◽  
Dna Analysis ◽  
Fish Bone ◽  
Genetic Identification ◽  
Identification Methods ◽  
Specific Identification ◽  
Southeast Queensland

Current genetic methods enable highly specific identification of DNA from modern fish bone. The applicability of these methods to the identification of archaeological fish bone was investigated through a study of a sample from late Holocene southeast Queensland sites. The resultant overall success rate of 2% indicates that DNA analysis is, as yet, not feasible for identifying fish bone from any given site. Taphonomic issues influencing the potential of genetic identification methods are raised and discussed in light of this result.

SPECIAL ARTICLE

PEDIATRICS ◽  
1956 ◽  
Vol 18 (5) ◽  
pp. 841-852
Author(s):  
W. L. Minear
Keyword(s):  
Cerebral Palsy ◽  
American Academy ◽  
Medical Record ◽  
Muscle Tone ◽  
Brain Lesion ◽  
Good Deal ◽  
The Other ◽  
Anatomical Site ◽  
First Choice

The majority of the members of the American Academy for Cerebral Palsy voted to exclude progressive neurological diseases and neoplastic diseases of the brain from the classification of cerebral palsy. The lesion left by the removal of a brain tumor, however, is still considered one of the etiological factors of cerebral palsy. Cerebral palsy comprises the motor and other symptom complexes caused by a non-progressive brain lesion (or lesions). The nomenclature and classification questionnaires indicate that the members of the American Academy for Cerebral Palsy wish to accept a motor classification, listing each type of cerebral palsy separately: Spastic, Athetoid, Tremor, Rigidity, Ataxic, Atonic, and Mixed. The following choices as a basis for classification of cerebral palsy were made by the American Academy for Cerebral Palsy: First choice: Motor Symptoms Second choice: Topographic Involvement Third choice: Etiology Fourth choice: Anatomical Site (of lesion) Fifth choice: Severity of Involvement Sixth choice: Degree of Muscle Tone Seventh choice: Supplemental Data The first 3 choices above should be used by the medical record librarian and by doctors discharging patients with cerebral palsy from hospitals or institutions so as to establish a common understanding and uniformity to hospital records. It is understood that the neuroanatomical classification (Fourth choice) is to be used when it can be proven, but not by presumption. The majority of the members approve of tension, non-tension, dystonic, and tremor-like types of athetosis. The other types were rejected for various reasons. Probably, some of the other types would have been accepted if understood by the members. Each type is described and defined herein. There is a general lack of agreement on the various terms used in cerebral palsy. Definitions of these terms are now being made by a committee for a meeting in 1955. There is a good deal of evidence that neurological signs and symptoms change in the child with cerebral palsy as the nervous system matures and that one must be cautious in making a final descriptive or symptomatic diagnosis in infancy. The pattern of changing neurological symptoms from infancy through childhood should be studied. The high cervical syndrome described by Fay is being confused with cerebral palsy. This syndrome needs further study. It should be determined whether the term cerebrospinal palsy would not be more appropriate for the entire neurological group. The American Medical Association's Standard Nomenclature of Diseases and Operations (Fourth Edition), commonly used by medical record librarians, is not suitable for the classification of cerebral palsy. In this edition, all cerebral palsy is coded "Cerebral spastic infantile paralysis" with supplementary terms added to denote various types. A complete classification for cerebral palsy is presented, using the majority opinion from questionnaires sent to the members of the American Academy for Cerebral Palsy during 1953 as a basis.

Impact of Social Media Readiness on Social Media Usage and Competitive Advantage

2019 ◽  
pp. 246-267
Author(s):  
Apoorv Durga ◽  
M. L. Singla
Keyword(s):  
Social Media ◽  
Competitive Advantage ◽  
Success Rate ◽  
Failure Rate ◽  
Media Use ◽  
The Other ◽  
Value Chains ◽  
Media Usage ◽  
Effective Implementation ◽  
Use Of Social Media

Usage of social media within organizations' value chains has been increasing rapidly. There are several benefits and savings projected due to usage of social media. As a result, there is also a lot of hype that is typical of any new web phenomenon. On the other hand, saner voices are cautioning against excessive hype and point to high failure rate of social media initiatives. Lack of best practices or frameworks and incomplete understanding of how to make best use of social media are some of the reasons cited for this high failure of social media initiatives. In addition, there are several other aspects related to governance, people, and processes that need to be addressed to improve success rate of these initiatives. Therefore, effective implementation of a social media initiative includes addressing all those aspects that relate to governance, people, and processes. The authors use a construct, “Social Media Readiness,” that encapsulates these aspects. This chapter summarizes research that shows how readiness can impact social media use.

Linnaeus, Carl von (1707–78)

2018 ◽  
Author(s):  
P.F. Stevens
Keyword(s):  
Classification System ◽  
Natural System ◽  
The Other ◽  
European Countries ◽  
Ecological Interactions ◽  
Wide Range ◽  
Divine Retribution ◽  
The World ◽  
Artificial Classification

Linnaeus was educated in Sweden, and became a doctor of medicine in Harderwijk, Holland, in 1735. He visited other European countries then, but he never left Sweden after his return in 1738. After practising as a physician in Stockholm, he moved to Uppsala University as professor of medicine and botany in 1741. He articulated four different but complementary ways of understanding nature – through two kinds of classification, and through what can be called developmental and functional/ecological interactions. Linnaeus is best known for his classificatory work, for which he received material from all over the world. His classificatory precepts are elaborated in the Philosophia botanica of 1751, an enlarged version of the 365 aphorisms of his Fundamenta botanica of 1735; the other aspects of his work are diffused through his writings. His artificial classification system, initially very popular, was replaced by the ’natural’ system, more slowly in botany than in zoology, and more slowly in England than in some other countries. Current biological nomenclature is based on his Species plantarum, edition 1 (for plants), and Systema naturae, edition 10 (for animals). His codification of botanical terms remains influential. Almost 200 dissertations, most written by Linnaeus, were defended by his students. In these and other less well-known works, including the unpublished Nemesis divina (Stories of Divine Retribution), he covered a wide range of subjects. Quinarian thinking is noticeable in Linnaeus’ work – there are five ranks in systems, five years’ growth in flowers – and in some of the occult works that he knew. He also shows a strong combinatorial bent and a tendency to draw close analogies between the parts of animals and plants.

A community clearing house for technological awareness information

1984 ◽  
Vol 8 (1) ◽  
pp. 13-17
Author(s):  
T.S. Eisenschitz ◽  
L.J. Wedlake
Keyword(s):  
Technology Transfer ◽  
Feasibility Study ◽  
Questionnaire Survey ◽  
Information Transfer ◽  
The Other ◽  
Clearing House ◽  
Member States ◽  
National Centre ◽  
Awareness Information ◽  
Transfer Agents

A feasibility study was carried out for the EEC to examine the possibility of establishing an international Clearing House to aid technology transfer. Recent and related initiatives to promote innovation and communications within the Commun ity are described. A scheme is put forward, based on the activities of Industrial Information Transfer agents who would collect information for a National Centre which would then forward it to the Clearing House. In return, National Centres would receive information from the other member states and disseminate it to users. Enthusiasm for such a scheme was demonstrated by means of a questionnaire survey which il lustrated problems but indicated basic approval of the scheme. Finally, suggestions are made for a more thorough evaluation of the scheme.

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