scholarly journals Halo Gravity Traction Is Associated with Reduced Bone Mineral Density of Patients with Severe Kyphoscoliosis

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Xiao Han ◽  
Weixiang Sun ◽  
Yong Qiu ◽  
Leilei Xu ◽  
Shifu Sha ◽  
...  
Keyword(s):  
Bone Mineral ◽  
Total Body Weight ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Femur Neck ◽  
The Mean ◽  
Baseline Characteristics ◽  
Total Body ◽  
Mineral Loss

Background. Halo gravity traction (HGT) is one of the most commonly used perioperative techniques for the treatment of severe kyphoscoliosis. This study was to explore the influence of HGT on the BMD of these patients.Methods. Patients with severe kyphoscoliosis treated by preoperative HGT for at least 2 months were included. Patients’ BMD were assessed by dual-energy X-ray absorptiometry at lumbar spine (LS, L2–L4) and femur neck (FN) of the nondominant side. The weight and duration of traction, as well as baseline characteristics, were recorded.Results. Twenty patients were recruited. The average traction duration was77.9±13.0days while the mean traction weight was39.9%±11.1% of total body weight. Remarkable decrease of BMD was observed at LS of 17 (85%) patients and at FN of 18 (90%) patients. After HGT, 75% of patients were found to have osteoporosis, the incidence of which was significantly higher than that before HGT (35%). The correlation analysis revealed BMD reduction was only significantly correlated with the traction duration.Conclusions. The current study showed that preoperative HGT can have obvious impact on the BMD. The BMD reduction is associated with traction duration, suggesting that long traction duration may bring more bone mineral loss.

scholarly journals AB0609 RADIOFREQUENCY ECHOGRAPHIC MULTI-SPECTROMETRY FOR THE ASSESSMENT OF BOTH FEMORA IN PREGNANT WOMEN

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1340.1-1340
Author(s):  
E. Kirilova ◽  
N. Kirilov ◽  
S. Vladeva
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Pregnant Women ◽  
Bone Mineral ◽  
Dual Energy ◽  
Z Score ◽  
Mineral Density ◽  
X Ray ◽  
The Mean ◽  
The Right

Background:Radiofrequency Echographic Multi-Spectrometry (REMS) is a non-ionizing innovative approach for the assessment of REMS-based bone mineral density (BMD) of the axial skeleton. The principle of the REMS technology is based on the analysis of native raw unfiltered ultrasound signals during an echographic scan of the lumbar spine or the femoral neck [1]. Several studies demonstrated the high concordance with dual energy X-ray absorptiometry (DXA) in terms of measured BMD with this novel technology [2,3]. In previous published literature it was envisaged to apply this technology for the examination of the axial bone density in pregnant women. Pregnancy-associated bone loss has been demonstrated as decreased bone mineral density (BMD) in previous studies [4].Objectives:The aim of the current study is to compare the BMD values of both femora between pregnant and non-pregnant women matched for age and BMI using the novel REMS technology.Methods:Of total fifty women twenty pregnant women (40%) and thirty non-pregnant women (60%) were included in the study. The mean age of the pregnant women was 32 years ± 5 standard deviations (SD), (range 25-41 years) and the mean age of the non-pregnant women was 30 years ± 6 standard deviations (SD), (range 24-39 years). REMS approach was used to assess REMS-based BMD and REMS-based Z-score values of the femoral neck. Furthermore, body mass index (BMI) and gestational age in weeks were evaluated.Results:The mean BMI of the pregnant women was 26 kg/m2 ± 7 kg/m2 (range 14 kg/m2-42 kg/m2) and those of the non-pregnant women was 25 kg/m2 ± 5 kg/m2 (range 16 kg/m2-35 kg/m2). The mean gestational age was 20 weeks’ gestation ± 5 weeks’ gestation (range 13-27 weeks’ gestation). REMS-based mean BMD of the left femoral neck of the pregnant women was 0.793 g/cm2 ± 0.167 g/cm2 (range 0.563 g/cm2-1.154 g/cm2). REMS-based mean BMD of the right femoral neck of the pregnant women was 0.828 g/cm2 ± 0.153 g/cm2 (range 0.570 g/cm2-1.161 g/cm2). After comparing left femoral neck BMD with the right femoral neck BMD of the pregnant women, we found a linear correlation (R=0.764). Left femoral neck BMD value (0.793 g/cm2) of the pregnant women was significantly lower than those of the non-pregnant women (0.854 g/cm2), p=0.002. The mean left femoral Z-score of the pregnant women (-0.1 SD with range -2.5 SD-2.9 SD) was also significantly lower compared to those of the non-pregnant women (1.2 SD with range -1.5 SD-3.1 SD), p=0.003.Conclusion:This is the first study which provides data about BMD and Z-score values of both femora in pregnant women assessed with the radiation-free REMS technology. Pregnant women demonstrated significantly lower femoral neck BMD values and Z-scores compared to those of the non-pregnant women. Innovative REMS method could be very helpful for making decision about the treatment of pregnant women who are at risk of lower BMD due to concomitant diseases and/or treatment associated with osteoporosis.References:[1]Casciaro S, Conversano F, Pisani P, Muratore M. New perspectives in echographic diagnosis of osteoporosis on hip and spine. Clin Cases Miner Bone Metab. 2015; 12(2):142-150.[2]Nikolov M, Nikolov N. AB0908 Assessment of the impact of the lean mass with body composition by dual-energy x-ray absorptiometry on the bone mineral density. Annals of the Rheumatic Diseases 2020; 79:1756.[3]Chakova M., Chernev D., Kashukeeva P., Krustev P., Abedinov F. Lumbar Sympathectomy - Literature Review. International Journal of Science and Research (IJSR) Volume 7 Issue 8, August 2018 ISSN (Online): 2319-7064.[4]Degennaro, V. A.; Cagninelli, G.; Lombardi, F. A. “VP34.12: First assessment of maternal status during pregnancy by means of radiofrequency echographic multi-spectrometry technology”. Ultrasound in Obstetrics & Gynecology. 2020, 56 (S1): 199.Disclosure of Interests:None declared.

scholarly journals Relationship between body mass index and osteoporosis

2016 ◽  
Vol 69 (suppl. 1) ◽  
pp. 85-88
Author(s):  
Radmila Matijevic ◽  
Vladimir Harhaji ◽  
Srdjan Ninkovic ◽  
Zoran Gojkovic ◽  
Predrag Rasovic ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Mass Index ◽  
Body Mass ◽  
Bone Mineral ◽  
Dual Energy ◽  
Normal Body Mass Index ◽  
Mineral Density ◽  
X Ray ◽  
T Score ◽  
The Mean

Introduction. Osteoporosis is a metabolic skeletal disease characterized by bone mineral density reduction, which may lead to an increased risk of bone fractures. Obesity is a condition of excessive body fat that causes or aggravates many public health problems. As it is easy to be measured, body mass index is widely used as an index of the degree of obesity. Material and Methods. The study included 1.372 female orthopedic patients between the ages of 30 to 79 years who visited the Clinical Centre of Vojvodina in Novi Sad to have a dual-energy x-ray absorptiometry (DEXA) examination in the period from March, 2010 to June, 2013. The following anthropometric data were collected: body mass index, body weight, height, dual-energy x-ray absorptiometry T-score and bone mineral density (BMD), as well as some other data. Results. The mean age was 62.08 years, the mean weight was 73.59 kg and the mean height was 1.6 m. There were 392 participants in the group of normal body mass index, 14 participants were underweight, and 966 were overweight and obese. In the overweight and obese group, 25.25% participants had osteoporosis, 35.4% had osteopenia and 39.33% had the normal T-score. In the normal body mass index group, 42.34% of the participants had osteoporosis, 29.3% had osteopenia and 28.31 had the normal T-score. In the underweight group, 57.14% of the participants had osteoporosis, 21.42% had osteopenia and 21.42% had the normal T-score. Conclusion. No strong correlation between body mass index and bone mineral density was found in our study, but it is obvious that there was a stronger correlation between body mass index and bone mineral density of the total hip than between body mass index and bone mineral density of the lumbar spine.

scholarly journals Comparison of Bone Mineral Densitometry at 2 Sites Versus 3 Sites in Patients Suspicious for Osteoporosis

2019 ◽  
Vol 12 ◽  
pp. 117954411984901 ◽  
Author(s):  
Ahad Azami ◽  
Hasan Anari ◽  
Manouchehr Iranparvar ◽  
Amin Azizi ◽  
Afshin Habibzadeh
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
T Score ◽  
Femur Neck ◽  
Bone Mineral Densitometry

Objectives: In this study, we aim to evaluate the bone mineral density (BMD) results of 2 standard sites with 3 sites including wrist in diagnosing osteoporosis. Methods: We evaluated the BMD results of 1272 individuals referred for suspected osteoporosis between 2012 and 2015. Those individuals were included with BMD at lumbar spine, femur neck, and wrist. Bone mineral density was measured using a dual-energy X-ray absorptiometry (DXA) device. Bone mineral density and T score were measured for all 3 sites. Results: There was significant correlation between wrist T score with hip T score ( r = 0.606, P < .001) and lumbar T score ( r = 0.527, P < .001). With BMD of 2 sites, patients had osteopenia in 46.3% and osteoporosis in 23.7%, while by adding wrist T-BMD, subjects had osteopenia in 46.6% and osteoporosis in 33%. Between BMD at 2 sites and 3 sites, there was concordance in 81.9%, minor discordance in 17.6%, and major discordance in 0.5%. Conclusions: We observed discordance between BMD measurements of 2 sites and 3 sites, with latter detecting more cases with osteoporosis. In fact, measurement of T scores of wrist along with lumbar and femur neck improves the diagnosis.

scholarly journals Impact of degenerative radiographic abnormalities and vertebral fractures on spinal bone density of women with osteoporosis

2002 ◽  
Vol 120 (1) ◽  
pp. 09-12 ◽  
Author(s):  
Lúcia Costa Paiva ◽  
Silvana Filardi ◽  
Aarão Mendes Pinto-Neto ◽  
Adil Samara ◽  
João Francisco Marques Neto
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Density ◽  
Bone Mineral ◽  
Vertebral Fractures ◽  
Dual Energy ◽  
X Rays ◽  
Mineral Density ◽  
X Ray ◽  
The Mean

CONTEXT: Measurements of bone density taken by dual-energy x-ray absorptiometry are the most accurate procedure for the diagnosis of osteoporosis. This procedure has the disadvantage of measuring the density of all mineral components, including osteophytes, vascular and extra vertebral calcifications. These alterations can influence bone density results and densitometry interpretation. OBJECTIVE: To correlate radiography and densitometry findings from women with osteoporosis, analyzing the influence of degenerative processes and vertebral fractures on the evaluation of bone density. DESIGN: Retrospective study. SETTING: Osteoporosis outpatients' clinic at Hospital das Clínicas, Universidade Estadual de Campinas. PARTICIPANTS: Ninety-six postmenopausal women presenting osteoporosis diagnosed by bone density. MAIN MEASUREMENTS: Bone mineral density of the lumbar spine and femoral neck were measured by the technique of dual-energy x-ray absorptiometry, using a LUNAR-DPX densitometer. Fractures, osteophytes and aortic calcifications were evaluated by simple x-rays of the thoracic and lumbar spine. RESULTS: The x-rays confirmed vertebral fractures in 41.6%, osteophytes in 33.3% and calcifications of the aorta in 30.2%. The prevalence of fractures and aortic calcifications increased with age. The mean bone mineral density was 0.783g/cm² and the mean T-score was --3.47 DP. Neither fractures nor aortic calcifications had significant influence on bone mineral density (P = 0.36 and P = 0.09, respectively), despite the fractured vertebrae having greater bone mineral density (P < 0.02). Patients with lumbar spine osteophytes showed greater bone mineral density (P = 0.04). Osteophytosis was associated with lumbar spine bone mineral density after adjustment for fractures and aortic calcifications by multiple regression (P = 0.01). CONCLUSION: Osteophytes and lumbar spine fractures can overestimate bone density interpretation. The interpretation of densitometry results should be carried out together with the interpretation of a simple lumbar spine x-ray in elderly women.

scholarly journals Η επίδραση της διατροφής και της άσκησης στην κατάσταση των οστών σε παιδιά πρώτης σχολικής ηλικίας

2020 ◽  
Author(s):  
Θεόδωρος Σταμπουλής
Keyword(s):  
Bone Mineral ◽  
Mineral Content ◽  
Vigorous Physical Activity ◽  
Hierarchical Cluster ◽  
Dual Energy ◽  
Bone Area ◽  
Mineral Density ◽  
X Ray ◽  
Total Body ◽  
One Way Anova

Η βελτίωση της κατάστασης των οστών επηρεάζεται από τη διατροφή και την άσκηση, χωρίς ωστόσο να έχουν τεκμηριωθεί οι επιδράσεις τους σε παιδιά πρώτης σχολικής ηλικίας. Σκοπός της παρούσας διδακτορικής διατριβής ήταν η μελέτη της επίδρασης της διατροφής και της άσκησης στους δείκτες οστικής περιεκτικότητας (Bone Mineral Content, BMC), οστικής πυκνότητας (Bone Mineral Density, BMD) και οστικής επιφάνειας (Bone Area, BA) σε παιδιά πρώτης σχολικής ηλικίας. Στη μελέτη συμμετείχαν 208 προ-έφηβα παιδιά (ηλικία: 8.59±0.92 έτη, ύψος: 136.12±10.58cm, βάρος: 33.99±9.38kg, ΔΜΣ: 18.08±3.17kg/m2, Σωματικό Λίπος: 28.93±10.11%). τα οποία υποβλήθηκαν σε αξιολόγηση των δεικτών οστικής κατάστασης BMC, BMD και ΒΑ στο σύνολο του σώματος (Total Body Less Head, TBLH), στην οσφυϊκή μοίρα της σπονδυλικής στήλης (Lumbar Sipne 1-4, L1-L4), στο σύνολο του μηριαίου οστού (Total Femur, TF) και στον αυχένα του μηριαίου οστού (Femoral Neck, FN) τόσο στο κυρίαρχο (Dominant, D) όσο και στο μη κυρίαρχο κάτω άκρο (Νon Dominant, ND) με τη χρήση της μεθόδου απορροφησιομετριάς ακτίνων Χ διπλής ενέργειας (Dual energy X-ray Absorptiometry, DXA). Η διαιτητική πρόσληψη των μακρο- και μικροθρεπτικών συστατικών αξιολογήθηκε με τη χρήση ημερολογίου καταγραφής τροφίμων, τα οποία αναλύθηκαν με τη χρήση του Science Fit Diet 200A. Για τον αντικειμενικό προσδιορισμό της άσκησης, ως σύνολο της ημερήσιας μέτριας προς έντονης φυσικής δραστηριότητας (moderate-to-vigorous physical activity, MVPA), πραγματοποιήθηκε καταγραφή της για 7 συνεχόμενες μέρες με τη χρήση επιταχυνσιομέτρου ActiGraph GT3X+. Για την ομαδοποίηση των παιδιών στις ομάδες συνδυασμού άσκησης και διατροφής και στις ομάδες διατροφής χρησιμοποιήθηκε η Ιεραρχική Ανάλυση Ομαδοποίησης (Hierarchical Cluster Analysis) και για την ομαδοποίηση των ομάδων άσκησης χρησιμοποιήθηκε η τεχνική ομαδοποίησης visual binning. Οπότε προέκυψαν οι ομάδες συνδυαστικής επίδρασης διατροφής κι άσκησης Α και Β, οι διατροφικές ομάδες χαμηλής πρόσληψης (ΧΠ), μέτριας πρόσληψης (ΜΠ) και υψηλής πρόσληψης (ΥΠ) των θρεπτικών συστατικών σχετικών με την οστική κατάσταση (πρωτεΐνη, ασβέστιο, βιταμίνη D και φώσφορος) και οι ισόποσες ομάδες άσκησης 1,2 και 3. Για την ανάλυση των επιδράσεων χρησιμοποιήθηκε η ανάλυση διακύμανσης ως προς έναν παράγοντα (One-Way ANOVA). Τα αποτελέσματα έδειξαν ότι η ομάδα Β είχε σημαντικά υψηλότερη διαφορά με την ομάδα Α στο δείκτη BMD του TF και FN τόσο στο D όσο και στο ND (p<0.005), με επιπλέον υψηλότερη διαφορά στο δείκτη BMC του FN του ND (p<0.05). Η ομάδα ΥΠ είχε σημαντικά υψηλότερες διαφορές στο δείκτη BMD του TF και FN τόσο του D όσο και του ND (p<0.05) με την ομάδα ΧΠ. Αναφορικά με την επίδραση της άσκησης, η ομάδα 3 είχε σημαντικά υψηλότερες διαφορές την ομάδα 1 στο δείκτη BMD του TF τόσο στο D όσο και στο ND, και στο FN του ND (p<0.05). Δεν εντοπίστηκαν σημαντικές διαφοροποιήσεις στο TBLH και στην L1-L4 σε κάποιο από του δείκτες BMC, BMD και ΒΑ. Συμπερασματικά, η συνδυαστική επίδραση διατροφής και άσκησης βελτίωσε BMD και BMC στα κάτω άκρα, η διατροφή βελτίωσε μόνο το δείκτη BMD στα κάτω άκρα ενώ η άσκηση επέδρασε κυρίως στο BMD του ND.

Effect of tamoxifen on bone mineral density measured by dual-energy x-ray absorptiometry in healthy premenopausal and postmenopausal women.

1996 ◽  
Vol 14 (1) ◽  
pp. 78-84 ◽  
Author(s):  
T J Powles ◽  
T Hickish ◽  
J A Kanis ◽  
A Tidy ◽  
S Ashley
Keyword(s):  
Breast Cancer ◽  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Premenopausal Women ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
The Mean

PURPOSE Tamoxifen is an effective treatment for metastatic and primary breast cancer and is now being evaluated as a chemoprevention agent in healthy women. Any long-term effects on estrogen-sensitive tissues such as bone may have important therapeutic implications. METHODS We measured bone mineral density (BMD) in the lumbar spine and hip using dual-energy x-ray absorptiometry (DXA) in premenopausal and postmenopausal healthy women who participated in our placebo-controlled tamoxifen chemoprevention of breast cancer trial. RESULTS BMD data are now available from 179 women for this analysis. In premenopausal women, BMD decreased progressively in the lumbar spine (P < .001) and in the hip (P < .05) for women on tamoxifen, but not those on placebo. The mean annual loss in lumbar BMD per year over the 3-year study period in tamoxifen-treated compliant women who remained premenopausal throughout the study period was 1.44% (1.88% calculated on an intent-to-treat basis) compared with a small gain of 0.24% per annum for women on placebo (P < .001). Tamoxifen had the opposite effect in postmenopausal women. The mean annual increase in BMD for women on tamoxifen was 1.17% in the spine (P < .005) and 1.71% in the hip (P < .001) compared with a noninsignificant loss for women on placebo. CONCLUSION These results indicate that tamoxifen treatment is associated with a significant loss of BMD in premenopausal women, whereas it prevents bone loss in postmenopausal women. These adverse and beneficial effects of tamoxifen should be considered in the assessment of the therapeutic benefits for both the adjuvant treatment and the chemoprevention of breast cancer.

scholarly journals Cross-Calibration of GE Healthcare Lunar Prodigy and iDXA Dual-Energy X-Ray Densitometers for Bone Mineral Measurements

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
J. Saarelainen ◽  
M. Hakulinen ◽  
T. Rikkonen ◽  
H. Kröger ◽  
M. Tuppurainen ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Linear Correction ◽  
Bone Mineral Measurements ◽  
Total Body ◽  
Cross Calibration

In long-term prospective studies, dual-energy X-ray absorptiometry (DXA) devices need to be inevitably changed. It is essential to assess whether systematic differences will exist between measurements with the new and old device. A group of female volunteers (21–72 years) underwent anteroposterior lumbar spine L2–L4 (n=72), proximal femur (n=72), and total body (n=62) measurements with the Prodigy and the iDXA scanners at the same visit. The bone mineral density (BMD) measurements with these two scanners showed a high linear association at all tested sites (r=0.962–0.995;p<0.0001). The average iDXA BMD values were 1.5%, 0.5%, and 0.9% higher than those of Prodigy for lumbar spine (L2–L4) (p<0.0001), femoral neck (p=0.048), and total hip (p<0.0001), respectively. Total body BMD values measured with the iDXA were −1.3% lower (p<0.0001) than those measured with the Prodigy. For total body, lumbar spine, and femoral neck, the BMD differences as measured with these two devices were independent of subject height and weight. Linear correction equations were developed to ensure comparability of BMD measurements obtained with both DXA scanners. Importantly, use of equations from previous studies would have increased the discrepancy between these particular DXA scanners, especially at hip and at spine.

scholarly journals Bone mineral density in healthy Syrian women measured by dual energy X-ray absorptiometry

2018 ◽  
Vol 81 (1) ◽  
pp. 18-28
Author(s):  
Mohamed Adel Bakir ◽  
Kholoud B Hammad ◽  
Khuzama M Habil
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Reference Values ◽  
Standard Technique ◽  
Dual Energy ◽  
Specific Reference ◽  
Mineral Density ◽  
X Ray ◽  
Femur Neck

Abstract Assessment of bone mineral density (BMD) using dual energy X-ray absorptiometry (DXA) technique is considered as a standard technique for diagnosing osteopenia and osteoporosis and evaluating the severity of such diseases. Numerous studies have demonstrated the necessity to establish an ethnic-specific reference data for Bone mineral density measurements. Such data are lacking for the Syrian population. The objectives of this study are (1) to establish BMD reference values in a group of healthy Syrian women using DXA technique, (2) to compare with values from other populations, (3) to study the prevalence of osteopenia and osteoporosis in Syrian women using the manufacturer reference values. A total of 951 healthy Syrian women aged 20-79 years participated in this study. Weight, height, and BMI have been determined. BMD measurements were performed using Lunar Prodigy Advance System (GE). The data were compared with those from other populations. The results have demonstrated the expected decline in BMD with age after peaking at 30-39 years old group. The peak values of the lumbar spine and femur neck were 1.16 (0.12), and 0.95 (0.13) g/cm2, respectively. The results of the Syrian women were compared with those from other populations and the differences were presented. Osteopenia was diagnosed in 35.80% and 60.31% and osteoporosis in 6.23% and 2.72% in lumbar spine and femur neck, respectively, of women 50-59 years of age. These ratios increased to 36.84%, 68.42% and 23.68%, 13.10%, respectively, in the age group more than 59 years. BMD values of the Syrian women were determined for the first time. The results demonstrate the importance of establishing population-specific reference range for BMD values for an accurate assessment of Osteoporosis. High prevalence of osteopenia and osteoporosis was demonstrated in Syrian using the manufacturer reference values.

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