scholarly journals DKA with Severe Hypertriglyceridemia and Cerebral Edema in an Adolescent Boy: A Case Study and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Tansit Saengkaew ◽  
Taninee Sahakitrungruang ◽  
Suttipong Wacharasindhu ◽  
Vichit Supornsilchai

A 13-year-old adolescent boy with type 1 diabetes mellitus (1b) presented with diabetic ketoacidosis (DKA) and cerebral edema. Grossly lipemic serum and lipemia retinals due to extremely high triglyceride (TG) level were observed without evidence of xanthoma or xanthelasma. Cerebral edema was treated by appropriate ventilation and mannitol administration. Normal saline was carefully given and regular insulin was titrated according to blood sugar levels. Triglyceride levels were reduced from 9,800 mg/dL to normal range within 9 days after conventional treatment was commenced without antilipid medication. Based on our review of the literature, this is the first reported case of confirmed pediatric DKA with severe hypertriglyceridemia and cerebral edema. In patients with DKA and hypertriglyceridemia, clinicians should be mindful of the possibility of associated acute pancreatitis and cerebral edema.

2021 ◽  
Vol 2 (1) ◽  
pp. 22
Author(s):  
Phaneendra Kumar

This case study is of a Diabetic person who works as an IT software engineer in Bangalore. Yoga Therapy Workshop was organized for 3 weeks (15 working days) in IT Company. The person showed interest in implementing the yoga therapy protocol for a longer duration to control her Diabetes. Her sense of well-being improved within one week of following the protocol which included Asanas, Meditation, Pranayam and Home Remedies such as Amla juice with Turmeric. She practiced yoga regularly and consumed 2 tablespoons of Amla Juice with 1 gram of Turmeric on an empty stomach for 90 consecutive days. She was not on any medication since she was diagnosed as a diabetic. Yoga has shown significant improvement in reversing the patient’s diabetes condition and returning her blood sugar levels to normal range.


2016 ◽  
Vol 29 (1) ◽  
pp. 43-45
Author(s):  
Rokshana Ivy ◽  
Rawshan Hosne Jahan ◽  
Anjuman Ara

We report a case of a 33 years primigravida who had regular antenatal check up and her pregnancy was uneventful till 30 weeks of pregnancy when she developed hypertension and her blood pressure was 150/90 mm of Hg. At that time urinary protein was trace and she was treated conservatively. At 33 weeks of pregnancy, her blood pressure raised to 160/105 mm of Hg along with mild proteinuria. Serum creatinine and uric acid levels were within normal range. Ultrasonography revealed 32 weeks pregnancy with fetal weight 1800 gm and AFI 7 cm. The patient was treated conservatively. At 36 weeks of pregnancy, the patient perceived less fetal movement and Biophysical profile was found 6. Emergency caesarean section was done. During operation, blood was found pinkish in colour and after keeping the placenta on kidney dish, milky fluid was accumulated around the placenta. Urgently lipid profile of the patient was done and the report revealed high Triglyceride (3012mg/dl) and cholesterol levels (348 mg/dl). The postoperative period was uneventful and she was treated with injection Heparin in the immediate postoperative period followed by low fat diet and lipid lowering agents.Bangladesh J Obstet Gynaecol, 2014; Vol. 29(1) : 43-45


2014 ◽  
Vol 155 (30) ◽  
pp. 1203-1206
Author(s):  
Tatjána Ábel ◽  
Katalin Sándor ◽  
Anna Tremmel ◽  
István Pénzes ◽  
Eldin_Mohamed Gamal ◽  
...  

The authors present the case of a 38-year-old woman with severe hypertriglyceridemia-induced acute recurrent pancreatitis (triglyceride 16 761 mg/dl, 189.4 mmol/l). According to the knowledge of the authors, such a high triglyceride has not been previously reported in Hungarian and international scientific literature. The patient received conventional treatment (fluid replacement, analgesic, antibiotics, discontinuation of oral intake) and plasmapheresis too. After two sessions of plasmapheresis with one month interval the clinical and laboratory parameters greatly improved. Severe hypertriglyceridemia (triglyceride level more than 1000 mg/dl, ≈11.3 mmol/l) is an independent risk factor for acute pancreatitis. Plasmapheresis seems to be safe and effective to rapidly decrease triglyceride levels and to remove the causative agent for pancreatitis in a patient with severe hypertriglyceridemia. Orv. Hetil., 2014, 155(30), 1203–1206.


2013 ◽  
Vol 44 (12) ◽  
pp. 2861-2864 ◽  
Author(s):  
Jennifer K. Sehn ◽  
Lindsay M. Kuroki ◽  
Margaret M. Hopeman ◽  
Ryan E. Longman ◽  
Colleen P. McNicholas ◽  
...  

Author(s):  
Melike Şahinol ◽  
Gülşah Başkavak

AbstractThe conventional treatment of Type 1 Diabetes (T1D) is especially demanding for children, both physically and psychologically (Iversen et al. Int J Qual Stud Health Well-being,13(1), 1487758, 2018). Continuous Glucose Monitoring Systems (CGM) are an important aid for children and their families in dealing with the disease. In their work, however, Şahinol and Başkavak (2020) point out that CGM carry the risk of viewing T1D as a technologically solvable problem instead of considering the disease as a whole. This is mainly creating confidence in technology due to CGM experiences while neglecting significant dietary measures and exercises needed to be integrated into daily routines. During the current pandemic, this problem seems to take on a whole new level. Based on two periods of in-depth interviews and observations conducted with 8 families with T1D children aged 6 to 14 living in Istanbul and Ankara (Turkey) from May to November 2019 and again from May to June 2020, we compare and focus on the experiences prior to and during the pandemic time. We argue that despite the possibility of technological regulation of the disease, the vulnerability of children is increased and, more than ever, depends on socio-bio-technical entanglements.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alicia J. Jenkins ◽  
Barbara H. Braffett ◽  
Arpita Basu ◽  
Ionut Bebu ◽  
Samuel Dagogo-Jack ◽  
...  

AbstractIn type 2 diabetes, hyperuricemia is associated with cardiovascular disease (CVD) and the metabolic syndrome (MetS), but associations in type 1 diabetes (T1D) have not been well-defined. This study examined the relationships between serum urate (SU) concentrations, clinical and biochemical factors, and subsequent cardiovascular events in a well-characterized cohort of adults with T1D. In 973 participants with T1D in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC), associations were defined between SU, measured once in blood collected 1997–2000, and (a) concurrent MetS and (b) incident ‘any CVD’ and major adverse cardiovascular events (MACE) through 2013. SU was higher in men than women [mean (SD): 4.47 (0.99) vs. 3.39 (0.97) mg/dl, respectively, p < 0.0001], and was associated with MetS features in both (men: p = 0.0016; women: p < 0.0001). During follow-up, 110 participants (11%) experienced “any CVD”, and 53 (5%) a MACE. Analyzed by quartiles, SU was not associated with subsequent CVD or MACE. In women, SU as a continuous variable was associated with MACE (unadjusted HR: 1.52; 95% CI 1.07–2.16; p = 0.0211) even after adjustment for age and HbA1c (HR: 1.47; 95% CI 1.01–2.14; p = 0.0467). Predominantly normal range serum urate concentrations in T1D were higher in men than women and were associated with features of the MetS. In some analyses of women only, SU was associated with subsequent MACE. Routine measurement of SU to assess cardiovascular risk in T1D is not merited.Trial registration clinicaltrials.gov NCT00360815 and NCT00360893.


Author(s):  
Yakhya Cisse ◽  
El Hadji Cheikh Ndiaye Sy ◽  
Abdoulaye Diop ◽  
Habibou Sarr ◽  
Louncény Fatoumata Barry ◽  
...  

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