scholarly journals A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Alexandra Chow ◽  
Noah J. Switzer ◽  
Jerry Dang ◽  
Xinzhe Shi ◽  
Christopher de Gara ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Meta Analysis ◽  
Insulin Requirement ◽  
Study Endpoint ◽  
Inclusion Criteria ◽  
Comprehensive Search ◽  
Bariatric Surgical Procedure

Background. The utility of bariatric surgery in type 1 diabetes remains controversial. The aim of the present study is to evaluate glycemic control outcomes in obese patients with type 1 diabetes after bariatric surgery.Methods. A comprehensive search of electronic databases was completed. Inclusion criteria included human adult subjects with BMI ≥35 kg/m2and a confirmed diagnosis of type 1 diabetes who underwent a bariatric surgical procedure.Results. Thirteen primary studies (86 patients) were included. Subjects had a mean age of41.16±6.76years with a mean BMI of42.50±2.65 kg/m2. There was a marked reduction in BMI postoperatively at 12 months and at study endpoint to29.55±1.76 kg/m2(P<0.00001) and30.63±2.09 kg/m2(P<0.00001), respectively. Preoperative weighted mean total daily insulin requirement was98±26 IU/d, which decreased significantly to36±15 IU/d (P<0.00001) and42±11 IU/d (P<0.00001) at 12 months and at study endpoint, respectively. An improvement inHbA1cwas also seen from8.46±0.78% preoperatively to7.95±0.55% (P=0.01) and8.13±0.86% (P=0.03) at 12 months and at study endpoint, respectively.Conclusion. Bariatric surgery in patients with type 1 diabetes leads to significant reductions in BMI and improvements in glycemic control.

scholarly journals Bone Mineral Density and Type 1 Diabetes in Children and Adolescents: A Meta-analysis

2021 ◽  
Author(s):  
Phoebe Loxton ◽  
Kruthika Narayan ◽  
Craig F Munns ◽  
Maria E Craig
Keyword(s):  
Bone Mineral Density ◽  
Type 1 Diabetes ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Meta Analysis ◽  
Inclusion Criteria ◽  
Mineral Density ◽  
Multiple Modalities ◽  
Meta Regression

<u>Background</u> <p>There is substantial evidence that adults with type 1 diabetes have reduced bone mineral density (BMD), however findings in youth are inconsistent.</p> <p><u>Purpose</u></p> <p>Systematic review and meta-analysis of BMD in youth with type 1 diabetes using multiple modalities: dual energy X-ray absorptiometry (DXA), peripheral quantitative computed tomography (pQCT) and/or quantitative ultrasound (QUS).</p> <p><u>Data Sources</u></p> <p>PubMed, Embase, Scopus and Web of Science from 01/01/1990 to 31/12/2020, limited to humans, without language restriction.</p> <p><u>Study Selection</u></p> <p>Inclusion criteria: cross sectional or cohort studies that included BMD measured either by DXA, pQCT and/or QUS in youth (age <20 years) with type 1 diabetes and matched controls. </p> <p><u>Data extraction</u></p> <p>Total body (TB), lumbar spine (LS) and femoral BMD (DXA); tibia, radius and lumbar spine (pQCT); and phalanx and calcaneum (QUS). Weighted mean difference (WMD) or standardized mean difference (SMD) were estimated and meta-regression was performed using age, diabetes duration and HbA1c as covariates.</p> <p><u>Data Synthesis </u></p> <p>We identified 1300 non-duplicate studies; 46 met the inclusion criteria, including 2617 cases and 3851 controls. Mean age was 12.6 ± 2.3 years. Youth with type 1 diabetes had lower BMD: TB (WMD -0.04 g/cm<sup>2</sup>, 95% CI -0.06 to -0.02, <i>P</i>=0.0006); LS (-0.02 g/cm<sup>2</sup>, -0.03 to -0.0, <i>P = 0.01</i>); femur (-0.04 g/cm<sup>2</sup>, -0.05 to -0.03, <i>P</i><0.00001); tibial trabecular (-11.32 g/cm<sup>3</sup>,-17.33 to -5.30, <i>P</i>=0.0002), radial trabecular (-0.91, -1.55 to -0.27, <i>P=0.005</i>); phalangeal (-0.32, -0.38 to -0.25, <i>P</i><0.00001) and calcaneal (SMD -0.69, -1.11 to -0.26, <i>P</i>=0.001). Using meta-regression TB BMD was associated with older age (coefficient -0.0063, -0.0095 to -0.0031, <i>P</i>=0.002), but not longer diabetes duration or HbA1c.</p> <p><u>Limitations</u></p> <p>Meta-analysis was limited by the small number of studies using QUS and pQCT and lack of use BMD z-scores in all studies. </p> <p><u>Conclusions</u></p> <p>Bone development is abnormal in youth with type 1 diabetes, assessed by multiple modalities. Routine assessment of BMD should be considered in all youth with type 1 diabetes.</p>

Bariatric Surgery in Patients with Type 1 Diabetes: A Meta-analysis of 104 Cases

2015 ◽  
Vol 11 (6) ◽  
pp. S166-S168
Author(s):  
Ali Aminian ◽  
John Kirwan ◽  
Bartolome Burguera ◽  
Sangeeta Kashyap ◽  
Philip Schauer ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Type 1 Diabetes ◽  
Meta Analysis

scholarly journals Type 1 Diabetes Mellitus and Bariatric Surgery: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 26 (8) ◽  
pp. 1697-1704 ◽  
Author(s):  
Hutan Ashrafian ◽  
Leanne Harling ◽  
Tania Toma ◽  
Christina Athanasiou ◽  
Nikolaos Nikiteas ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Bariatric Surgery ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Meta Analysis

scholarly journals Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis

2020 ◽  
Vol 10 (2) ◽  
pp. 98-115 ◽  
Author(s):  
Majid Mobasseri ◽  
Masoud Shirmohammadi ◽  
Tarlan Amiri ◽  
Nafiseh Vahed ◽  
Hossein Hosseini Fard ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 1 Diabetes ◽  
Web Of Science ◽  
Meta Analysis ◽  
Inclusion Criteria ◽  
Glucose Levels ◽  
The World ◽  
Multiple Levels ◽  
English Articles

Background: Diabetes is referred to a group of diseases characterized by high glucose levels in blood. It is caused by a deficiency in the production or function of insulin or both, which can occur because of different reasons, resulting in protein and lipid metabolic disorders. The aim of this study was to systematically review the prevalence and incidence of type 1 diabetes in the world. Methods: A systematic search of resources was conducted to investigate the prevalence and incidence of type 1 diabetes in the world. The databases of Medline (via PubMed and Ovid),ProQuest, Scopus, and Web of Science from January 1980 to September 2019 were searched to locate English articles. The located articles were screened in multiple levels of title, abstract,and full-text and final studies that met the inclusion criteria were retrieved and included in the study. Results: From 1202 located articles, 193 studies were included in this systematic review. The results of meta-analysis showed that the incidence of type 1 diabetes was 15 per 100,000 people and the prevalence was 9.5% (95% CI: 0.07 to 0.12) in the world, which was statistically significant. Conclusion: According to the results, the incidence and prevalence of type 1 diabetes are increasing in the world. As a result, insulin will be difficult to access and afford, especially in underdeveloped and developing countries.

scholarly journals Bariatric Surgery Induces Weight Loss but Does Not Improve Glycemic Control in Patients With Type 1 Diabetes

Diabetes Care ◽  
2014 ◽  
Vol 37 (8) ◽  
pp. e173-e174 ◽  
Author(s):  
Matthias Lannoo ◽  
Bruno Dillemans ◽  
Yves Van Nieuwenhove ◽  
Steffen Fieuws ◽  
Chantal Mathieu ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Type 1 Diabetes ◽  
Glycemic Control

Association Between Adherence and Glycemic Control in Pediatric Type 1 Diabetes: A Meta-analysis

PEDIATRICS ◽  
2009 ◽  
Vol 124 (6) ◽  
pp. e1171-e1179 ◽  
Author(s):  
K. K. Hood ◽  
C. M. Peterson ◽  
J. M. Rohan ◽  
D. Drotar
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Meta Analysis ◽  
Pediatric Type 1 Diabetes
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