scholarly journals Surviving All Odds: A Unique Case of Multiple Congenital Unruptured Sinus of Valsalva Aneurysms Involving Both Left and Right Coronary Sinuses with Biventricular Dysfunction and Heart Block

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Aniketh Vijay B ◽  
Vikrant Vijan ◽  
Navin Mathew

Aneurysms of the sinus of Valsalva are very uncommon, with an incidence ranging from 0.1 to 3.5% of all congenital heart defects. Very few cases have been reported in the literature that presented with involvement of two or more sinuses. We report a case of 27-year-old male with a history of exertional breathlessness of one-month duration. After complete evaluation using transesophageal echocardiography (TEE) and multiple detector computed tomography (MDCT) scanning, the patient was diagnosed to have large congenital unruptured sinus of Valsalva aneurysms involving both left and right coronary sinuses with extension into the interventricular septum. The patient also displayed second-degree heart block (Mobitz type 2) and biventricular dysfunction. The patient was managed successfully. We present the case with an aim to highlight the management challenges including intraoperative and postoperative complications that are associated with unruptured sinus of Valsalva aneurysms of ≥2 sinuses.

2005 ◽  
Vol 13 (3) ◽  
pp. 283-286 ◽  
Author(s):  
Durgaprasad Rajashekar ◽  
Gangapatnam Subramanyam ◽  
Rao Panchamukheswar ◽  
Maddirala Praveen ◽  
Sonuguri Guruprasad

We present a patient with bilateral unruptured sinus of Valsalva aneurysms involving both the left and right coronary sinuses. The large left sinus aneurysm protruded into the left atrium and the right sinus aneurysm extended into the interventricular septum, producing a transient complete heart block.


2017 ◽  
Vol 31 (12) ◽  
pp. 1691-1697 ◽  
Author(s):  
Alessandro Mantovani ◽  
Riccardo Rigolon ◽  
Isabella Pichiri ◽  
Giovanni Morani ◽  
Stefano Bonapace ◽  
...  

Circulation ◽  
1971 ◽  
Vol 44 (6) ◽  
pp. 1087-1095 ◽  
Author(s):  
JOSEPH F. SPEAR ◽  
E. NEIL MOORE

1971 ◽  
Vol 27 (6) ◽  
pp. 682-686 ◽  
Author(s):  
Jacob I. Haft ◽  
Murray Weinstock ◽  
Ramiro DeGuia

Author(s):  
Gurkirat Singh ◽  
Mahesh Bodkhe ◽  
Aditya Gupta ◽  
Narender Omprakash Bansal

The dissection of the sinus of Valsalva aneurysm into the interventricular septum leading to complete heart block is a rare complication with only few cases reported in the literature. We report a case of young farm laborer, who presented with multiple episodes of syncope. Upon clinical evaluation, we found third-degree atrioventricular block due the rupture of right sinus of Valsalva into the interventricular septum.


2018 ◽  
Vol 35 (12) ◽  
pp. 2109-2112 ◽  
Author(s):  
Hala Fennich ◽  
Nawal Doghmi ◽  
Fagouri Rim ◽  
Saad Belhaj ◽  
Fatima Cheikhi ◽  
...  

2018 ◽  
Vol 52 (6) ◽  
pp. 505-512 ◽  
Author(s):  
Bridgette Kram ◽  
Maegan Greenland ◽  
Mollie Grant ◽  
Michael E. Campbell ◽  
Charlotte Wells ◽  
...  

Background: Neostigmine is traditionally administered intravenously for treatment of acute colonic pseudo-obstruction (ACPO), though use is associated with administration constraints and adverse effects. Objective: To evaluate whether an alternative route of administration for neostigmine via subcutaneous (SQ) delivery is safe and effective in a broad cohort of medical and surgical patients. Methods: This multicenter, retrospective observational study included adult patients administered SQ neostigmine for ileus, ACPO, or refractory constipation. Efficacy indicators were time to first bowel movement (BM) following initiation of the medication, total SQ neostigmine dose administered to produce a BM, and administration of a rescue intervention to produce a BM. Safety events evaluated were cardiac arrest, bradycardia, bronchospasm requiring intervention, nausea requiring intervention, or severe salivation, lacrimation, or diarrhea. Results: A total of 182 patients were eligible for inclusion. The most commonly utilized dosing strategy of neostigmine was 0.25 mg SQ 4 times daily. The median time to first BM following initiation of SQ neostigmine was 29.19 hours (interquartile range = 12.18-56.84) with a median dose administered before first BM of 1.25 mg. Three patients (1.65%) experienced an adverse drug event leading to drug discontinuation, with 2 developing bradycardia that resolved with drug discontinuation alone. Conclusions: SQ neostigmine may be reasonable for management of ileus, ACPO, or refractory constipation, though use should be avoided in patients with new-onset heart block, a history of second-degree heart block, or following bowel resection with primary anastomosis. Despite the low incidence of adverse drug events observed, monitoring for bradycardia with telemetry may be considered.


Sign in / Sign up

Export Citation Format

Share Document