scholarly journals Lung Transplant Recipient with Pulmonary Alveolar Proteinosis

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Sofya Tokman ◽  
M. Frances Hahn ◽  
Hesham Abdelrazek ◽  
Tanmay S. Panchabhai ◽  
Vipul J. Patel ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Lung Transplant ◽  
Pulmonary Alveolar Proteinosis ◽  
Mammalian Target Of Rapamycin ◽  
Organ Transplant ◽  
Lung Transplant Recipient ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Solid Organ Transplant Recipients ◽  
Alveolar Proteinosis

Pulmonary alveolar proteinosis (PAP) is a progressive lung disease characterized by accumulated surfactant-like lipoproteinaceous material in the alveoli and distal bronchioles. This accumulation is the result of impaired clearance by alveolar macrophages. PAP has been described in 11 solid organ transplant recipients, 9 of whom were treated with mammalian target of rapamycin inhibitors. We report a case of a lung transplant recipient treated with prednisone, mycophenolate mofetil (MMF), and tacrolimus who ultimately developed PAP, which worsened when MMF was replaced with everolimus.

scholarly journals FusariumInfection in a Kidney Transplant Recipient Successfully Treated with Voriconazole

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Ahmed M. Alkhunaizi ◽  
Ali M. Bazzi ◽  
Ali A. Rabaan ◽  
Elwaleed A. Ahmed
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
High Mortality ◽  
Kidney Transplant Recipient ◽  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Organ Transplant Recipients ◽  
Solid Organ Transplant Recipients

Fusariuminfections in solid-organ transplant recipients are rare and carry high mortality. We report a case of a kidney transplant recipient who developed infection withFusariumspecies. The patient received treatment with oral voriconazole for five months with good response.

Providing post-lung transplant care during the time of COVID-19

2021 ◽  
Vol 30 (16) ◽  
pp. 976-980
Author(s):  
Sara Winward ◽  
Iain Lawrie ◽  
Susan Talbot Towell ◽  
Nina Sheridan ◽  
Patricia Ging
Keyword(s):  
Lung Transplant ◽  
Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Model Of Care ◽  
Community Based Interventions ◽  
Community Based ◽  
Solid Organ Transplant Recipients ◽  
Remote Monitoring Systems ◽  
Lung Transplant Recipients

The COVID-19 pandemic is a public health emergency of international concern. Solid organ transplant recipients have been identified as being at high risk of acquiring the virus SARS-CoV-2 and having a more severe COVID-19 disease. This article describes the experience of the National Lung Transplant Centre in Ireland in changing established care pathways for lung transplant recipients during the pandemic. The innovations which were put in place to protect this clinically vulnerable group are discussed. With the advancement of technology and remote monitoring systems available, patient-focused strategies and community-based interventions were implemented. Additional strategies have been implemented so that the new model of care can be safely maintained.

Aspergillus Infections among Solid Organ Transplant Recipients: A Case Study

1997 ◽  
Vol 7 (4) ◽  
pp. 187-189
Author(s):  
Joann Pfundstein
Keyword(s):  
Mortality Rate ◽  
Transplant Recipient ◽  
Heart Transplant ◽  
Organ Transplant ◽  
Heart Transplant Recipient ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Solid Organ Transplant Recipients

Infection remains a major cause of morbidity and mortality among transplant recipients. Aspergillus infections in particular are associated with a high mortality rate. The diagnosis of Aspergillus among transplant recipients may be difficult, because many patients have multiple complications. This article presents a case of Aspergillus in a heart transplant recipient. The discussion provides an overview of the presentation, diagnosis, and treatment of Aspergillus infections.

scholarly journals InvasiveMicroascus trigonosporusSpecies Complex Pulmonary Infection in a Lung Transplant Recipient

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Kelly E. Schoeppler ◽  
Martin R. Zamora ◽  
Noelle M. Northcutt ◽  
Gerard R. Barber ◽  
Gayle O’Malley-Schroeder ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Lung Transplant ◽  
Drug Exposure ◽  
Fungal Infections ◽  
Organ Transplant ◽  
Antifungal Prophylaxis ◽  
Lung Transplant Recipient ◽  
Invasive Infection ◽  
Solid Organ ◽  
High Incidence

Because of the high incidence of morbidity and mortality associated with invasive fungal infections, antifungal prophylaxis is often used in solid organ transplant recipients. However, this prophylaxis is not universally effective and may contribute to the selection of emerging, resistant pathogens. Here we present a rare case of invasive infection caused byMicroascus trigonosporusspecies complex in a human, which developed during voriconazole prophylaxis in a lung transplant recipient. Nebulized liposomal amphotericin B was used in addition to systemic therapy in order to optimize antifungal drug exposure; this regimen appeared to reduce the patient’s fungal burden. Despite this apparent improvement, the patient’s pulmonary status progressively declined in the setting of multiple comorbidities, ultimately leading to respiratory failure and death.

scholarly journals An Atypical Subcutaneous Cytomegalovirus Infection Mimicking a Post-transplant Lymphoproliferative Disorder in a Solid Organ Transplant Recipient

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Tae Young Park ◽  
Su Young Kim ◽  
Suk Hyun Bae ◽  
Sang Youb Han
Keyword(s):  
Transplant Recipient ◽  
Lymphoproliferative Disorder ◽  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Cmv Infection ◽  
Organ Transplant Recipients ◽  
Post Transplant ◽  
Solid Organ Transplant Recipients

: Cytomegalovirus (CMV) infection is a common cause of morbidity and mortality in solid organ transplant recipients and immunocompromised hosts. However, tissue-invasive CMV infection, causing cutaneous or subcutaneous diseases, has been rarely reported in the literature, and proper diagnosis can be easily delayed due to the rarity. Here, we report a rare case of a 45-year-old male renal transplant recipient, presenting with subcutaneous nodules. The nodules were initially suspected as a post-transplant lymphoproliferative disorder (PTLD) on CT scan. However, biopsy later indicated a CMV infection. Based on the present findings, clinicians and radiologists are suggested to consider CMV infection as a differential diagnosis of subcutaneous nodular lesions in solid organ transplant recipients.

scholarly journals Heart transplant recipient survivor from COVID-19: The first case of Turkey

2020 ◽  
Vol 28 (4) ◽  
pp. 674-679
Author(s):  
Güle Çınar
Keyword(s):  
Transplant Recipient ◽  
Heart Transplant ◽  
Organ Transplant ◽  
Heart Transplant Recipient ◽  
Solid Organ Transplant ◽  
Primary Concern ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Organ Transplant Recipients ◽  
Solid Organ Transplant Recipients

Any highly infectious and rapidly spreading disease is a primary concern for immunocompromised solid organ transplant recipients. The number of data about the spectrum of clinical illness, the treatment modalities, and the outcomes of COVID-19 in this vulnerable population is scant and still remains empirical. Herein, we report the first COVID-19 case of a heart transplant recipient in Turkey who presented with fever, postnasal discharge, and myalgias for two days. The possibility of lung involvement was ruled out by thoracic computed tomography. Despite stable vital signs, we reduced the intensity of immunosuppressive therapy and maintained home self-isolation promptly. We also commenced a five-day course of hydroxychloroquine 200 mg q12h initially. After confirmation of real-time reverse-transcriptase-polymerase-chain-reaction testing of the nasopharyngeal swab positive for COVID-19, the patient was hospitalized. After a loading dose of favipiravir 1,600 mg b.i.d., the patient received a five-day course of favipiravir 600 mg q12h. He was discharged with cure after 23 days of hospital isolation and treatment. In conclusion, treatment process can be affected by the daily electrocardiography, hand-held portable echocardiography, myocardial injury markers, and pulse oximeter for self-monitoring in the follow-up of previous heart transplant recipients suffering from COVID-19. The lack of treatment protocols in the solid organ transplant recipients with COVID-19 infection and the controversies about the protective effect of immunosuppression invite a global and update discussion.

Urban Spread of Flaviviruses: A New Challenge in Solid-organ Transplant Recipients

2019 ◽  
Vol 70 (1) ◽  
pp. 149-151
Author(s):  
Paolo Antonio Grossi
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Yellow Fever ◽  
Kidney Transplant Recipient ◽  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
The World ◽  
Solid Organ Transplant Recipients

Abstract Yellow fever has never previously been reported in transplant recipients. The first reported case of yellow fever in a kidney transplant recipient in Brazil and the re-emergence of arboviruses in many areas of the world dictate the need of studies aimed to answer multiple unanswered questions.

Sign in / Sign up

Export Citation Format

Share Document