scholarly journals Multifactorial Etiology Pulmonary Hypertension in a Patient with Sarcoidosis

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Barreto Ana Terra Fonseca ◽  
Barreto Lucas Vinícius da Fonseca ◽  
Cavalcante Felipe Naze Rodrigues ◽  
Oliveira Joselina Luzia Menezes ◽  
Almeida-Santos Marcos Antônio ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Differential Diagnosis ◽  
Case Report ◽  
Clinical Practice ◽  
Clinical Outcome ◽  
Adult Patient ◽  
Diastolic Heart Failure ◽  
Poor Clinical Outcome ◽  
Worse Prognosis

Differential diagnosis between pre- and postcapillary pulmonary hypertension (PH) in patients with diastolic heart failure (DHF) is a challenge in clinical practice. The presence of PH is implicated in worse prognosis in patients with this disease. This case report approaches the process of investigation of pulmonary hypertension in adult patient with DHF, double mitral lesion, and sarcoidosis with poor clinical outcome.

Sheehan Syndrome Leading to Acute Systolic and Diastolic Heart Failure: A Case Report

2021 ◽  
Vol 40 (4) ◽  
pp. S476-S477
Author(s):  
A.T. Lemieux ◽  
K. Kopecky ◽  
W. Sovic ◽  
A. Patel ◽  
A. Bindra
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Diastolic Heart Failure ◽  
Sheehan Syndrome

Abstract 14608: Prognostic Value of Diuretic Resistance in Patients Admitted for Acute Decompensated Heart Failure With Reduced, Mid-range, or Preserved Left Ventricular Ejection Fraction

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Takanari Kimura ◽  
Takahisa Yamada ◽  
Tetsuya Watanabe ◽  
Takashi Morita ◽  
Yoshio Furukawa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Ejection Fraction ◽  
Clinical Outcome ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Poor Clinical Outcome ◽  
Ventricular Ejection Fraction ◽  
Diuretic Resistance

Background: Diuretic resistance is associated with poor clinical outcome in patients with acute decompensated heart failure (ADHF). However, little information is available on the prognostic significance of diuretic resistance in ADHF patients, relating to reduced, mid-range, or preserved left ventricular ejection fraction (LVEF). Methods: We studied 400 consecutive patients who were admitted for ADHF and survived to discharge. Diuretic resistance (DR) was defined by furosemide dose per body weight (BW) at discharge. Patients were classified by DR, and high dose group (higher DR) was defined by furosemide dose of > median value of DR (0.580). The endpoint was a composite of all-cause mortality and unplanned hospitalization for worsening heart failure. Results: There were 139 patients with heart failure with reduced LVEF (HFrEF, LVEF<40%), 86 with mid-range LVEF (HFmrEF, 40%≤LVEF<50%) and 175 with preserved LVEF (HFpEF, LVEF≥50%). There was no significant difference in DR among the three groups (HFrEF; median 0.541 [IQR 0.360-0.786] mg/kg vs HFmrEF; 0.606 [0.398-0.820] mg/kg vs HFpEF; 0.624 [0.380-0.935] mg/kg, p=NS). During follow-up of 2.4±1.6 years, 195 patients reached the endpoint (HFrEF, n=67, HFmrEF, n=44, and HFpEF, n=84). In multivariate Cox analysis, DR was significantly associated with the endpoint independently of age, estimated glomerular filtration rate, plasma brain natriuretic peptide level and LVEF only in HFpEF patients (p<0.0001). Kaplan-Meier analysis showed that the risk of the endpoint was significantly higher in the patients with higher DR in HFpEF patients, but not in HFrEF or HFmrEF patients (Figure). Conclusions: In this study, higher DR was shown to be associated with poor clinical outcome in HFpEF patients admitted with ADHF.

scholarly journals Gastroblastoma in Adulthood—A Rarity among Rare Cancers—A Case Report and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Giovanni Centonze ◽  
Alessandro Mangogna ◽  
Tiziana Salviato ◽  
Beatrice Belmonte ◽  
Laura Cattaneo ◽  
...  
Keyword(s):  
Young Adults ◽  
Differential Diagnosis ◽  
Case Report ◽  
Clinical Approach ◽  
Review Of The Literature ◽  
Adult Age ◽  
Rare Cancers ◽  
Mesenchymal Neoplasm ◽  
Worse Prognosis

Gastroblastoma (GB) is a rare gastric epithelial-mesenchymal neoplasm, first described by Miettinen et al. So far, all reported cases described the tumor in children or young adults, and similarities with other childhood blastomas have been postulated. We report a case of GB in a 43-year-old patient with long follow up and no recurrence up to 100 months after surgery. So far, this is the second case of GB occurring in the adult age >40-year-old. Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.

scholarly journals Diastolic heart failure - case report

2005 ◽  
Vol 130 (19) ◽  
pp. 1207-1207
Author(s):  
A G Schmidt ◽  
B Pieske
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Diastolic Heart Failure ◽  
Heart Failure Case

scholarly journals Acute Myeloid Leukemia With a Rare t(7;14)(q21;q32) and Trisomy 4 With Poor Clinical Outcome: A Case Report

2017 ◽  
Vol 48 (4) ◽  
pp. 376-380
Author(s):  
Seema B Jabbar ◽  
Sara Monaghan ◽  
Weina Chen ◽  
Prasad Koduru ◽  
Kirthi Kumar
Keyword(s):  
Acute Myeloid Leukemia ◽  
Case Report ◽  
Clinical Outcome ◽  
Myeloid Leukemia ◽  
Poor Clinical Outcome ◽  
Acute Myeloid

scholarly journals LncRNA RHPN1-AS1 promotes cholangiocarcinoma progression and predicts poor clinical outcome through miR-345-5p/YAP1 axis

2020 ◽  
Author(s):  
Lifeng Ma ◽  
Tao Li ◽  
Guochao Liu ◽  
Jianlong Wang ◽  
Zhaoqiang Yin ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Clinical Practice ◽  
Clinical Outcome ◽  
Carcinoma Cell ◽  
Poor Clinical Outcome ◽  
Xenograft Growth ◽  
Poor Outcome ◽  
New Strategies

Abstract Background LncRNAs have proven to be involved in the initiation and progression of cholangiocarcinoma (CCA), although the mechanism by which this occurs remains unknown. Methods The current study reveals that RHPN1-AS1 was overexpressed in CCA patient samples, which predicted poor outcome of CCA patients. RHPN1-AS1 increased in vitro pancreatic carcinoma cell proliferation as well as promoted xenograft growth in vivo. Mechanistically, DANCR upregulated expression of YAP1 by competitively binding to miR-345-5p. Importantly, RHPN1-AS1 level was positively correlated with YAP1 expression level in CCA tissues. Moreover, YAP1 overexpression could predicted a poor outcome of CCA patients. Results Taken together, our results suggested that RHPN1-AS1 might be a remarkable biomarker to evaluate prognosis in CCA. Conclusion The RHPN1-AS1/YAP1 axis may provide new strategies for CCA clinical practice.

scholarly journals Giant Intrapericardial Bronchogenic Cyst Associated with Congestive Heart Failure and Atrial Fibrillation:  A Case Report

2020 ◽  
Author(s):  
Javier Maldonado ◽  
German Molina ◽  
Francisco M- Rincón T ◽  
Lina M. Acosta Buitrago ◽  
Carlos J- Perez Rivera
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Congestive Heart Failure ◽  
Differential Diagnosis ◽  
Case Report ◽  
Bronchogenic Cyst ◽  
De Novo ◽  
Pathological Findings ◽  
Case Presentation ◽  
Bronchogenic Cysts

Abstract Background: Large intracardiac bronchogenic cysts are rare mediastinal masses, however they must always be considered in the differential diagnosis of heart failure. Case Presentation: We present a 60-year-old female patient with de novo atrial fibrillation and heart failure, resulting from an incidental large intrapericardial mass. The patient underwent successful surgical resection, with pathological findings confirming a bronchogenic cyst.Conclusions: Large bronchogenic cysts located intrapericardially are very rare, however they should be included in the differential diagnosis of patients presenting with atrial fibrillation and heart failure.

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