scholarly journals Characterization Method for 3D Substructure of Nuclear Cell Based on Orthogonal Phase Images

2015 ◽  
Vol 2015 ◽  
pp. 1-8
Author(s):  
Ying Ji ◽  
Minjie Liang ◽  
Tingting Hua ◽  
Yuanyuan Xu ◽  
Zhiduo Xin ◽  
...  
Keyword(s):  
Mononuclear Cell ◽  
Blood Cells ◽  
Cell Model ◽  
Simulation Technique ◽  
Biological Cells ◽  
Phase Images ◽  
Phase Mutation ◽  
Nuclear Cell ◽  
Orthogonal Phase ◽  
Different Parts

A set of optical models associated with blood cells are introduced in this paper. All of these models are made up of different parts possessing symmetries. The wrapped phase images as well as the unwrapped ones from two orthogonal directions related to some of these models are obtained by simulation technique. Because the phase mutation occurs on the boundary between nucleus and cytoplasm as well as on the boundary between cytoplasm and environment medium, the equation of inflexion curve is introduced to describe the size, morphology, and substructure of the nuclear cell based on the analysis of the phase features of the model. Furthermore, a mononuclear cell model is discussed as an example to verify this method. The simulation result shows that characterization with inflexion curve based on orthogonal phase images could describe the substructure of the cells availably, which may provide a new way to identify the typical biological cells quickly without scanning.

Sub-surface quick imaging of typical blood cells based on orthogonal phase images by rotating method

Optik ◽  
2015 ◽  
Vol 126 (24) ◽  
pp. 5026-5029
Author(s):  
Yawei Wang ◽  
Linlin Zhang ◽  
Yuanyuan Xu ◽  
Ying Ji ◽  
Li Zhang ◽  
...  
Keyword(s):  
Blood Cells ◽  
Phase Images ◽  
Orthogonal Phase

scholarly journals Numerical simulations of blood cell flow in non-Newtonian fluid

2020 ◽  
Vol 306 ◽  
pp. 01006
Author(s):  
Kazuhiro Shitara ◽  
Toru Hyakutake
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Newtonian Fluid ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Cell Model ◽  
Flow Behavior ◽  
Shear Thinning ◽  
Mutual Interference ◽  
Axial Concentration

We investigated how non-Newtonian viscosity behavior affects the flow characteristics of blood cells. Our findings offer insight about how shear thinning affects the dispersion of liposome-encapsulated hemoglobin and red blood cells in blood. The lattice Boltzmann method was used for fluid calculations, and the rheological properties of the non-Newtonian fluid were modeled with power-law relationships. The deformable three-dimensional red blood cell model was applied. First, we investigated the effects of shear thinning on the flow behavior of single blood cell. Simulation results indicate that shear thinning promotes the axial concentration of red blood cells. Next, varied the hematocrit to see how mutual interference between blood cells affects flow. At low hematocrit, shear thinning clearly promotes the axial concentration of red blood cells. As the hematocrit increases, in contrast, mutual interference has a greater effect, which counteracts shear thinning so the red blood cell distribution resembles the distribution within a Newtonian fluid.

Autologous Red Blood Cells Potentiate Antibody Synthesis by Unfractionated Human Mononuclear Cell Cultures

1987 ◽  
Vol 26 (2) ◽  
pp. 119-127 ◽  
Author(s):  
M. T. RUGELES ◽  
M. LA VIA ◽  
J.-M. GOUST ◽  
J. M. KILPATRICK ◽  
B. HYMAN ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Mononuclear Cell ◽  
Cell Cultures ◽  
Blood Cells ◽  
Antibody Synthesis ◽  
Human Mononuclear Cell

Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia

Blood ◽  
2001 ◽  
Vol 98 (5) ◽  
pp. 1577-1584 ◽  
Author(s):  
Kitty de Jong ◽  
Renee K. Emerson ◽  
James Butler ◽  
Jacob Bastacky ◽  
Narla Mohandas ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Blood Cells ◽  
Cell Model ◽  
Red Cell ◽  
Sickle Cells ◽  
Red Cell Survival ◽  
Transgenic Murine Models

Several transgenic murine models for sickle cell anemia have been developed that closely reproduce the biochemical and physiological disorders in the human disease. A comprehensive characterization is described of hematologic parameters of mature red blood cells, reticulocytes, and red cell precursors in the bone marrow and spleen of a murine sickle cell model in which erythroid cells expressed exclusively human α, γ, and βS globin. Red cell survival was dramatically decreased in these anemic animals, partially compensated by considerable enhancement in erythropoietic activity. As in humans, these murine sickle cells contain a subpopulation of phosphatidylserine-exposing cells that may play a role in their premature removal. Continuous in vivo generation of this phosphatidylserine-exposing subset may have a significant impact on the pathophysiology of sickle cell disease.

Electro-Optical Frequency Mapping Phase Image Simulation Technique for Failure Analysis

2017 ◽  
Author(s):  
Junpei Nonaka ◽  
Nakaba Matsui ◽  
Seiichi Honbu ◽  
Kazuki Shigeta ◽  
Yukihisa Funatsu
Keyword(s):  
Failure Analysis ◽  
Simulation Method ◽  
Simulation Technique ◽  
Phase Image ◽  
Optical Frequency ◽  
Image Simulation ◽  
Circuit Layout ◽  
Phase Images ◽  
Logic Cells

Abstract We propose a phase image simulation method for Electro-Optical Frequency Mapping (EOFM). The proposed method eases the matching of phase images and circuit layout data, which was previously difficult because phase images are very complex. Physical failure analysis based on this matching result is enabled. Further works are required for understandings of simulated phase images in compound logic cells having many states or high-Z states.

A Comparison of the Number of Circulating Blood Cells in Different Parts of the Circulatory System

Science ◽  
1951 ◽  
Vol 113 (2935) ◽  
pp. 363-364 ◽  
Author(s):  
D. L. Azarnoff ◽  
T. V. Batty ◽  
P. G. Roofe ◽  
M. Maffet
Keyword(s):  
Blood Cells ◽  
Circulatory System ◽  
Different Parts
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