scholarly journals Dynamical Analysis of SIR Epidemic Model with Nonlinear Pulse Vaccination and Lifelong Immunity

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Wencai Zhao ◽  
Juan Li ◽  
Xinzhu Meng

SIR epidemic model with nonlinear pulse vaccination and lifelong immunity is proposed. Due to the limited medical resources, vaccine immunization rate is considered as a nonlinear saturation function. Firstly, by using stroboscopic map and fixed point theory of difference equations, the existence of disease-free periodic solution is discussed, and the globally asymptotical stability of disease-free periodic solution is proven by using Floquet multiplier theory and differential impulsive comparison theorem. Moreover, by using the bifurcation theorem, sufficient condition for the existence of positive periodic solution is obtained by choosing impulsive vaccination period as a bifurcation parameter. Lastly, some simulations are given to validate the theoretical results.

2007 ◽  
Vol 2007 ◽  
pp. 1-10 ◽  
Author(s):  
Shujing Gao ◽  
Zhidong Teng ◽  
Juan J. Nieto ◽  
Angela Torres

Pulse vaccination, the repeated application of vaccine over a defined age range, is gaining prominence as an effective strategy for the elimination of infectious diseases. An SIR epidemic model with pulse vaccination and distributed time delay is proposed in this paper. Using the discrete dynamical system determined by the stroboscopic map, we obtain the exact infection-free periodic solution of the impulsive epidemic system and prove that the infection-free periodic solution is globally attractive if the vaccination rate is larger enough. Moreover, we show that the disease is uniformly persistent if the vaccination rate is less than some critical value. The permanence of the model is investigated analytically. Our results indicate that a large pulse vaccination rate is sufficient for the eradication of the disease.


2016 ◽  
Vol 2016 ◽  
pp. 1-18
Author(s):  
Xiangsen Liu ◽  
Binxiang Dai

An SIR epidemic model with saturated treatment function and nonlinear pulse vaccination is studied. The existence and stability of the disease-free periodic solution are investigated. The sufficient conditions for the persistence of the disease are obtained. The existence of the transcritical and flip bifurcations is considered by means of the bifurcation theory. The stability of epidemic periodic solutions is discussed. Furthermore, some numerical simulations are given to illustrate our results.


2008 ◽  
Vol 01 (02) ◽  
pp. 147-160 ◽  
Author(s):  
YONGZHEN PEI ◽  
SHAOYING LIU ◽  
LANSUN CHEN ◽  
CHUNHUA WANG

Two different vaccination and treatment strategies in the SIR epidemic model with saturation infectious force are analyzed. With the continuous vaccination and treatment, it is obtained that the disease free equilibrium and endemic equilibrium are globally asymptotically stable by using Lassall theorem and Pioncare–Bendixon trichotomy. Moreover, with pulse vaccination and treatment at different time, the dynamics of the epidemic model is globally investigated by using Floquet theory and comparison theorem of impulsive differential equation and analytic method. We obtain the conditions of global asymptotical stability of the infection-free periodic solution and permanence of the model. Finally, we compare the two different vaccination and treatment strategies, and obtain that the elimination of disease is independent of treatment in the case of the pulse vaccination.


2016 ◽  
Vol 462 ◽  
pp. 816-826 ◽  
Author(s):  
Qun Liu ◽  
Daqing Jiang ◽  
Ningzhong Shi ◽  
Tasawar Hayat ◽  
Ahmed Alsaedi

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