scholarly journals Comparison between the Traditional and a Rapid Screening Test for Cryoimmunoglobulins Detection

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Federica Romitelli ◽  
Leopoldo Paolo Pucillo ◽  
Umberto Basile ◽  
Enrico Di Stasio
Keyword(s):  
Screening Test ◽  
Low Cost ◽  
Rapid Test ◽  
Rapid Screening ◽  
Serum Samples ◽  
Rapid Screening Test ◽  
Design And Methods ◽  
Kinetics Of ◽  
Maximum Turbidity

Objectives. A new rapid, automatic, and sensitive screening test useful to detect cryoglobulins in serum samples is proposed.Design and Methods. The increase of turbidity during the cryoglobulin aggregation was monitored spectrophotometrically in sera from 400 patients with clinical evidence of cryoglobulinemia related disorders and 100 controls. Results were correlated to those obtained by the traditional method.Results. Kinetics of the aggregation curves were described by their maximum turbidity increase, lag time, and slope. Despite a partial correspondence between the traditional and the rapid test, patients with symptomatic cryoglobulinemia showed turbidity values significantly higher than the determined cutoff. Moreover, a functional classification of cryoglobulins is proposed.Conclusions. Due to its high reproducibility, operator independence, low cost, and results obtained within 2 hours, the rapid test can be used as a “real time” monitoring of cryoglobulinemia related diseases and for the evaluation of plasmapheresis efficacy.

Rapid Screening Test for the Evaluation of Quaternary Ammonium Compounds by Triphenyltetrazolium Chloride Reduction by Microorganisms

1970 ◽  
Vol 53 (6) ◽  
pp. 1224-1228
Author(s):  
Raymond J Sitkiewicz
Keyword(s):  
Quaternary Ammonium ◽  
Screening Test ◽  
Rapid Test ◽  
Test System ◽  
Quaternary Ammonium Compounds ◽  
Rapid Screening ◽  
Ammonium Compound ◽  
Triphenyltetrazolium Chloride ◽  
Rapid Screening Test ◽  
Ammonium Compounds

Abstract A rapid screening test has been developed to determine killing dilutions of quaternary ammonium compounds. Two factors, Letheen broth as a quaternary ammonium compound neutralizer and triphenyltetrazolium chloride as a microbial growth indicator, resulted in a rapid test system for the evaluation of quaternary ammonium compounds. This rapid test system takes from 4 to 8 hr to complete as opposed to the 24 to 48 hr for other tests. A new germicide can be bacteriologically screened in one day.

scholarly journals A rapid screening test by the latex antistreptolysin O test for streptococcal infections in CMS Teaching Hospital, Bharatpur, Nepal

1970 ◽  
Vol 6 (2) ◽  
pp. 24-28
Author(s):  
BL Dewasy ◽  
YI Singh ◽  
BK Jha ◽  
J Kapil
Keyword(s):  
Rheumatic Fever ◽  
Screening Test ◽  
Serological Test ◽  
Latex Agglutination ◽  
Rapid Screening ◽  
Streptococcal Infections ◽  
Serum Samples ◽  
Rheumatic Arthritis ◽  
Rapid Screening Test ◽  
Group A

Streptococcus pyogenes (group A Streptococci) infection is diagnosed by either bacterial culture or serological test. For the serodiagnosis, antistreptolysin O (ASO) and antideoxyribonuclease B (DNAase B) are the most widely accepted tests. To measure the antibodies (ASO) of Streptococcus with the help of Rapitex antistreptolysin as a screening test is widely used in cases of suspected streptococcal infections and its sequelae. There were 4230 serum samples of rheumatic fever, glomerulonephritis, rheumatic heart disease and rheumatic arthritis. They were tested for Antistreptolysin O (ASO) antibodies by latex agglutination test. The test is very simple, cheap, rapid, convenient and reliable. Correlation with the clinical diagnosis is possible for routine use. Key Words: ASO; rheumatic fever; latex agglutination DOI: 10.3126/jcmsn.v6i2.3613 Journal of college of Medical Sciences-Nepal, 2010, Vol.6, No-2, 24-28

scholarly journals Significance of screening tests in diagnosis of infectious mononucleosis

2008 ◽  
Vol 61 (9-10) ◽  
pp. 489-496
Author(s):  
Gordana Kovacevic ◽  
Ivana Hrnjakovic-Cvjetkovic ◽  
Vesna Milosevic ◽  
Vera Jerant-Patic ◽  
Jelena Radovanov-Tadic ◽  
...  
Keyword(s):  
Virus Infection ◽  
Young Children ◽  
Screening Test ◽  
Rapid Test ◽  
Elisa Test ◽  
Screening Tests ◽  
Rapid Screening ◽  
Specific Antibodies ◽  
Ebv Infection ◽  
Rapid Screening Test

The investigation included 91 patients in who an acute or previous EBV infection was established by ELISA test. All patients were also subjected to the Paul-Bunnell-Davidsohn test, while 20 patients were tested by the rapid screening test Clearview IM. The diagnosis of acute infective mononucleosis was in 61 patients (67%) confirmed by the Elisa test, and in 12 patients (19.67 %) by the Paul-Bunnell-Davidsohn test, while the rapid screening test Clearview IM demonstrated too low a detection of heterophile antibodies. The rapid screening test was not reliable. In 25% cases, the test was invalid, at early infection stages the rapid test failed to diagnose any case of the EBV virus infection. Paull-Bunell-Davidsohn was often negative, especially with young children. Therefore, priority should be given to virology tests based on the detection of specific antibodies to EBV antigen.

scholarly journals D-karyo—A New Prenatal Rapid Screening Test Detecting Submicroscopic CNVs and Mosaicism

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 337
Author(s):  
Osamu Shimokawa ◽  
Masayoshi Takeda ◽  
Hiroyasu Ohashi ◽  
Akemi Shono-Ota ◽  
Mami Kumagai ◽  
...  
Keyword(s):  
Screening Test ◽  
Low Cost ◽  
Screening Method ◽  
Turnaround Time ◽  
Copy Number Variations ◽  
Rapid Screening ◽  
High Price ◽  
Chromosomal Microarray ◽  
Chromosomal Microarray Analysis ◽  
Rapid Screening Test

Chromosomal microarray analysis (CMA), recently introduced following conventional cytogenetic technology, can detect submicroscopic copy-number variations (CNVs) in cases previously diagnosed as “cytogenetically benign”. At present, rapid and accurate chromosomal analysis is required in prenatal diagnostics, but prenatal CMA is not widely used due to its high price and long turnaround time. We introduced a new prenatal screening method named digital karyotyping (D-karyo), which utilizes a preimplantation genetic test for the aneuploidy (PGT-A) platform. First, we conducted a preliminary experiment to compare the original PGT-A method to our modified method. Based on the preliminary results, we decided to implement the modified strategy without whole-genome amplification (WGA) and combined it with three analytical software packages. Next, we conducted a prospective study with 824 samples. According to the indication for invasive tests, the D-karyo positive rates were 2.5% and 5.0%, respectively, in the screening positive group with NT ≥ 3.5 mm and the group with fetal abnormalities by ultrasound. D-karyo is a breakthrough modality that can detect submicroscopic CNVs ≥ 1.0 Mb accurately in only 10.5 h for 24 samples at a low cost. Implementing D-karyo as a prenatal rapid screening test will reduce unnecessary CMA and achieve more accurate prenatal genetic testing than G-banding.

Rapid screening test for porphyrinuria

1970 ◽  
Vol 102 (2) ◽  
pp. 237-237
Author(s):  
R. M. McDonald
Keyword(s):  
Screening Test ◽  
Rapid Screening ◽  
Rapid Screening Test

A Rapid Screening Test for Detection of Poisons in Blood

Nature ◽  
1962 ◽  
Vol 193 (4822) ◽  
pp. 1298-1298 ◽  
Author(s):  
H. V. STREET
Keyword(s):  
Screening Test ◽  
Rapid Screening ◽  
Rapid Screening Test

Erythrocyte adenosine transport a rapid screening test for cardiovascular drugs

1993 ◽  
Vol 30 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Pollen K.F. Yeung ◽  
Susan J. Mosher ◽  
Rongshi Li ◽  
Patrick S. Farmer ◽  
Gerald A. Klassen ◽  
...  
Keyword(s):  
Screening Test ◽  
Cardiovascular Drugs ◽  
Rapid Screening ◽  
Rapid Screening Test ◽  
Adenosine Transport
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