scholarly journals Giant Abdominoperineal Malignant Schwannoma: An Unusual Presentation and Surgical Challenge

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Pankaj Panwar ◽  
Santosh Kumar ◽  
Shivanshu Singh ◽  
Ajjoor Shankargowda Sriharsha ◽  
Kirti Gupta
Keyword(s):  
Peripheral Nerves ◽  
Benign Tumor ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
Malignant Schwannoma ◽  
Atypical Presentation ◽  
First Case ◽  
Pelvic Tumors ◽  
Pelvic Nerves ◽  
Initial Biopsy

Schwannoma is a benign tumor arising from the Schwann cells of peripheral nerves. These are usually benign but malignant transformation can occur in larger lesions. The definitive diagnosis of malignancy can only be made after final histopathological report. The literature reports large pelvic and perineal schwannomas with few being malignant. We report the first case of such giant malignant abdominoperineal schwannoma which was benign on initial biopsy but final histopathology revealed it to be malignant. In view of proximity of perineal and pelvic tumors to urogenital organs and pelvic nerves, such cases represent a challenge to surgical excision. This case brings to highlight another atypical presentation of such tumors.

scholarly journals Breast schwannoma – a rare entity

Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Juliana Lopes de Aguiar Araujo ◽  
Ubiratan Wagner de Sousa ◽  
Ana Tereza Diniz Marinho de França ◽  
Lourdes Maria Dantas de Góis
Keyword(s):  
Skin Lesion ◽  
Schwann Cells ◽  
Myelin Sheath ◽  
Peripheral Nerves ◽  
Cellular Proliferation ◽  
Benign Tumor ◽  
Spindle Cell ◽  
Surgical Excision ◽  
Metaplastic Carcinoma ◽  
Spindle Cell Neoplasm

Introduction: Schwannoma is a benign tumor originating from Schwann cells present in the myelin sheath of peripheral nerves. Breast presentation is rare, and its clinical manifestation can mimic that of breast carcinoma. Objectives: To report the case of a patient with breast Schwannoma. Method/Case report: T.S.L., 14 years old, presented a nodule in the left breast (LB) with local growth for 2 months. Ultrasound (US) revealed a cystic formation in the lower outer quadrant of 1.8x1.3 cm, BI-RADS 2. Physical examination indicated a nodular skin lesion next to the LB fold, with 2 cm at 5 h, 7 cm from the nipple. After the surgical excision of the nodule, anatomopathological examination showed a spindle cell neoplasm without nodular-pattern atypia or malignancy characteristics. Immunohistochemistry (IHC) confirmed the Schwannoma diagnosis. Considering this scenario, annual control was started, and the patient has no evidence of the disease after 5 years of diagnosis. Results/Discussion: Schwannoma is a typically benign tumor originating from Schwann cells in the myelin sheath of the nerves. It may result from the parasympathetic or sympathetic division of the autonomic nervous system of the organ. It is one of the few truly encapsulated tumors of the human body and almost always solitary. It is usually located in the trunk, flexor surfaces, retroperitoneum, and rarely in the breast, representing approximately 2.6% of Schwannoma cases. It affects individuals aged 30 to 50 years, with equal incidence in both men and women. The skin lesion presents as a sessile, asymptomatic nodule of 1–3 cm and slow growth. Pain and sensitivity may be present when tumor growth causes nerve compression. Mammography (MMG) shows well-circumscribed opacity, with a density similar to that of soft tissue. US usually reveals well-defined, hypoechoic, solid lesions and can include the target sign, posterior acoustic enhancement, and continuity with peripheral nerves. The definitive diagnosis is made histologically, and the differential diagnosis involves other spindle cell neoplasms, such as fibroadenoma, phyllodes tumor, leiomyoma, fibromatosis, and, rarely, metaplastic carcinoma. Fine-needle aspiration biopsy (FNAB) showed palisading fibrillar cells with non-atypical spindle-shaped nuclei forming Verocay bodies. IHC indicates intense and uniform expression of S-100 protein. Malignant transformation occurs in 3–10% of cases, with high cellular proliferation, atypical mitotic activity, cellular and nuclear pleomorphism, and foci of necrosis. The treatment of choice is surgical excision of the lesion. Tumor recurrence is low and associated with the mitotic index. Conclusion: The case reported and publications found bring to light the discussion on diagnosis and treatment of breast Schwannoma, a rare and benign neoplasm in this location.

scholarly journals A Rare Schwannoma Of The Submandibular Gland: A Case Report

2018 ◽  
Vol 2 (1) ◽  
pp. 38
Author(s):  
Mohd Shaiful Nizam Mamat Nasir ◽  
Bathma Dhevi Susibalan ◽  
Mohd Najeb Md Soleh ◽  
Nor Hafliza Md Salleh ◽  
Irfan Mohamad
Keyword(s):  
Case Report ◽  
Submandibular Gland ◽  
Peripheral Nerves ◽  
East Coast ◽  
Neck Region ◽  
Surgical Excision ◽  
Tertiary Hospital ◽  
Benign Tumors ◽  
Head And Neck Region ◽  
First Case

Schwannomas are benign tumors arising from Schwann cells of the sheaths of peripheral nerves. Although vagus nerve and sympathetic chain composed of sympathetic fibers is one of the most common sites of schwannomas in extracranial head and neck region, many cases of origin unknown schwannomas were reported. We report an unusual rare case of a submandibular gland schwannoma in a 67-year-old lady, who was successfully treated by surgical excision with no cranial nerve deficits and complete resolution of the symptoms postoperatively. In this report, we establish a rare findings of schwannoma of the submandibular gland and to the best of our knowledge, this is the first case-report of schwannoma of submandibular gland reported from a tertiary hospital in the east coast of Malaysia.International Journal of Human and Health Sciences Vol. 02 No. 01 Jan’18. Page : 38-40

scholarly journals Surgical Removal of a Focal Fibrous Hyperplasia: Two Case Reports

2021 ◽  
Vol 6 (03) ◽  
pp. 188-191
Author(s):  
Zemmouri Yousra ◽  
Chbicheb Saliha
Keyword(s):  
Oral Cavity ◽  
Histological Examination ◽  
Oral Mucosa ◽  
Benign Tumor ◽  
Case Reports ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
Surgical Removal ◽  
Local Irritation

Focal fibrous hyperplasia is the most common epithelial benign tumor of the oral cavity. It is a localized reactive progressive, proliferation of oral mucosa in response to injury or local irritation. Females are twice more likely to develop fibroma than male. Surgical excision is performed and histological examination of the excised specimen and definitive diagnosis was obtained. This paper reports two cases of focal fibrous hyperplasia in both maxillary and mandibular locations.

Fibrolipomatous Hamartoma of Nerve in the Great Toe

2014 ◽  
Vol 104 (5) ◽  
pp. 531-534 ◽  
Author(s):  
Praya Mam ◽  
Ebony B. Lewis ◽  
Tex Song ◽  
Bradley W. Bakotic
Keyword(s):  
Peripheral Nerves ◽  
Benign Tumor ◽  
Soft Tissue Mass ◽  
Fluid Collection ◽  
Surgical Excision ◽  
Foot And Ankle ◽  
Great Toe ◽  
Tissue Mass ◽  
Fibrolipomatous Hamartoma ◽  
Rare Benign Tumor

Fibrolipomatous hamartoma is a rare benign tumor characterized by infiltration of fibrous and adipose tissue found within the epineurium and perineurium of the distal peripheral nerves. Most commonly seen in the upper extremities and median nerve, it is rarely involved in the foot and ankle. We report a rare case of fibrolipomatous hamartoma found in the great toe of a 25-year-old patient. Magnetic resonance imaging demonstrated a heterogeneous mass, confirming the mass was solid rather than a fluid collection. Surgical excision revealed a fatty, fibrous, well-demarcated, encapsulated, solid soft-tissue mass. A surgical excision was performed and a pathologic diagnosis of fibrolipomatous hamartoma was made.

scholarly journals A Case of Schwannoma of the Lateral Aspect of the Superficial Peroneal Nerve

2021 ◽  
Vol 111 (2) ◽  
Author(s):  
Adi Pajazetovic ◽  
Amram Dahukey
Keyword(s):  
Peripheral Nerves ◽  
Peroneal Nerve ◽  
Benign Tumor ◽  
Surgical Excision ◽  
Superficial Peroneal Nerve ◽  
Lateral Aspect ◽  
Neurogenic Origin ◽  
Pathologic Analysis ◽  
Neural Sheath

A schwannoma is a benign tumor with a neurogenic origin that affects peripheral nerves. It arises from the neural sheath of the peripheral nerves. We present a case of a 54-year-old woman who presented to our clinic with a painful schwannoma of her superficial peroneal nerve at the level of the ankle. The patient was treated with surgical excision, and diagnosis was confirmed with pathologic analysis.

scholarly journals Lipofibromatous Hamartoma of the Palmar Cutaneous Branch of the Median Nerve

2018 ◽  
Vol 10 (02) ◽  
pp. 109-112 ◽  
Author(s):  
Jason Hoellwarth ◽  
Robert Goitz
Keyword(s):  
Median Nerve ◽  
Peripheral Nerves ◽  
Benign Tumor ◽  
Excisional Biopsy ◽  
Mass Effect ◽  
First Case ◽  
Palmar Cutaneous Branch ◽  
Patient Reported ◽  
Cutaneous Branch ◽  
Lipofibromatous Hamartoma

Abstract Background Lipofibromatous hamartoma (LFH) is a benign tumor of peripheral nerves, most commonly reported in the median nerve, and often associated with carpal tunnel symptoms. There have been nearly 200 reported cases of LFH in the median nerve, but to the authors’ knowledge, this 10-year-old girl represents the first case report involving the palmar cutaneous branch. Methods An excisional biopsy of the mass was performed via a standard midline palmar incision. The tumor was found encapsulating the palmar cutaneous branch, and thus it was sacrificed. Results The incision healed without issue, but the patient reported numbness in the palm of her hand as was expected. Conclusion LFH is a benign tumor, although it can cause symptoms due to mass effect. If the diagnosis is uncertain or a patient is symptomatic, excisional biopsy can be performed even if involving a cutaneous nerve.

scholarly journals An Exceptional Case of Intraparotid Plexiform Neurofibroma Originating from Autonomic Fibers of the Auriculotemporal Nerve

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Sarantis Blioskas ◽  
Sotiris Sotiriou ◽  
Katerina Rizou ◽  
Triantafyllia Koletsa ◽  
Petros Karkos ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Plexiform Neurofibroma ◽  
Surgical Excision ◽  
Neurofibromatosis Type ◽  
Exceptional Case ◽  
Benign Tumors ◽  
First Case ◽  
Superficial Lobe ◽  
The Right ◽  
Auriculotemporal Nerve

Plexiform neurofibromas are benign tumors that tend to occur in patients suffering from neurofibromatosis type 1 (NF-1). This report addresses a rare case where the tumor affected the parotid gland, deriving almost exclusively from the peripheral portion of the facial nerve. A 6-year-old male was referred to us complaining about a gradually enlarging swelling over the right parotid area. Imaging localized the lesion to the superficial lobe of the parotid gland, suggesting a neurofibroma. Cosmetic disfigurement and a functional deficit led us to perform complete surgical resection. Meticulous surgical dissection as well as auriculotemporal nerve origin made complete extirpation possible with almost zero morbidity and ensured alleviation of both aesthetic impairment and pain. This is the first case of an intraparotid PN in a pediatric NF-1 patient, which originated from branches of the auriculotemporal nerve and particularly from fibers of the autonomic nervous system. Radical surgical excision was decided according to established decision-making algorithms.

scholarly journals Two Unusual Aspects of Posterior Reversible Encephalopathy Syndrome Mimicking Primary and Secondary Brain Tumor Lesions

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Mazamaesso Tchaou ◽  
Nicoleta Modruz ◽  
Lama K. Agoda-Koussema ◽  
Anthony Michelot ◽  
Samer Naffa ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Posterior Reversible Encephalopathy Syndrome ◽  
Cerebral Metastasis ◽  
Atypical Presentation ◽  
Radiological Outcome ◽  
Posterior Reversible Encephalopathy ◽  
First Case ◽  
Clinical And Radiological Outcome ◽  
Reversible Encephalopathy

The posterior reversible encephalopathy syndrome (PRES) is a rare clinical-radiological entity well described with typical clinical and radiological manifestations. Atypical presentation, especially in imaging, exists. The authors report here two cases of posterior reversible encephalopathy in which imaging aspects were atypical, mimicking, in the first case, hemorrhagic cerebral metastasis of cholangiocarcinoma and, in the second case, a brain tumor. The diagnosis has been retrospectively rectified due to clinical and radiological outcome.

scholarly journals Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. ar.2015.6.0127 ◽  
Author(s):  
Juliette O. Flam ◽  
Christopher D. Brook ◽  
Rachel Sobel ◽  
John C. Lee ◽  
Michael P. Platt
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nasal Symptoms ◽  
First Case ◽  
Nasal Tumor ◽  
Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

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