scholarly journals Does Moderate Intensity Exercise Attenuate the Postprandial Lipemic and Airway Inflammatory Response to a High-Fat Meal?

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Stephanie P. Kurti ◽  
Sara K. Rosenkranz ◽  
Morton Levitt ◽  
Brooke J. Cull ◽  
Colby S. Teeman ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inflammatory Response ◽  
Airway Inflammation ◽  
Exhaled Nitric Oxide ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Postprandial Period ◽  
Acute Bout ◽  
Fat Meal

We investigated whether an acute bout of moderate intensity exercise in the postprandial period attenuates the triglyceride and airway inflammatory response to a high-fat meal (HFM) compared to remaining inactive in the postprandial period. Seventeen (11 M/6 F) physically active (≥150 min/week of moderate-vigorous physical activity (MVPA)) subjects were randomly assigned to an exercise (EX; 60%VO2peak) or sedentary (CON) condition after a HFM (10 kcal/kg, 63% fat). Blood analytes and airway inflammation via exhaled nitric oxide (eNO) were measured at baseline, and 2 and 4 hours after HFM. Airway inflammation was assessed with induced sputum and cell differentials at baseline and 4 hours after HFM. Triglycerides doubled in the postprandial period (~113 ± 18%,P<0.05), but the increase did not differ between EX and CON. Percentage of neutrophils was increased 4 hours after HFM (~17%), but the increase did not differ between EX and CON. Exhaled nitric oxide changed nonlinearly from baseline to 2 and 4 hours after HFM(P<0.05, η2=0.36). Our findings suggest that, in active individuals, an acute bout of moderate intensity exercise does not attenuate the triglyceride or airway inflammatory response to a high-fat meal.

scholarly journals Effect of exercise intensity on postprandial lipemia, markers of oxidative stress, and endothelial function after a high-fat meal

2016 ◽  
Vol 41 (12) ◽  
pp. 1278-1284 ◽  
Author(s):  
Renata Lopes Krüger ◽  
Bruno Costa Teixeira ◽  
Juliano Boufleur Farinha ◽  
Rodrigo Cauduro Oliveira Macedo ◽  
Francesco Pinto Boeno ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Endothelial Function ◽  
Acute Exercise ◽  
Postprandial Lipemia ◽  
Moderate Intensity ◽  
Thiobarbituric Acid Reactive Substance ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Postprandial Period ◽  
Fat Meal

The aim of this study was to compare the effects of 2 different exercise intensities on postprandial lipemia, oxidative stress markers, and endothelial function after a high-fat meal (HFM). Eleven young men completed 2-day trials in 3 conditions: rest, moderate-intensity exercise (MI-Exercise) and heavy-intensity exercise (HI-Exercise). Subjects performed an exercise bout or no exercise (Rest) on the evening of day 1. On the morning of day 2, an HFM was provided. Blood was sampled at fasting (0 h) and every hour from 1 to 5 h during the postprandial period for triacylglycerol (TAG), thiobarbituric acid reactive substance (TBARS), and nitrite/nitrate (NOx) concentrations. Flow-mediated dilatation (FMD) was also analyzed. TAG concentrations were reduced in exercise conditions compared with Rest during the postprandial period (P < 0.004). TAG incremental area under the curve (iAUC) was smaller after HI-Exercise compared with Rest (P = 0.012). TBARS concentrations were reduced in MI-Exercise compared with Rest (P < 0.041). FMD was higher in exercise conditions than Rest at 0 h (P < 0.02) and NOx concentrations were enhanced in MI-Exercise compared with Rest at 0 h (P < 0.01). These results suggest that acute exercise can reduce lipemia after an HFM. However, HI-Exercise showed to be more effective in reducing iAUC TAG, which might suggest higher protection against postprandial TAG enhancement. Conversely, MI-Exercise can be beneficial to attenuate the susceptibility of oxidative damage induced by an HFM and to increase endothelial function in the fasted state compared with Rest.

scholarly journals Is the effect of prior exercise on postprandial lipaemia the same for a moderate-fat meal as it is for a high-fat meal?

2010 ◽  
Vol 105 (4) ◽  
pp. 506-516 ◽  
Author(s):  
Nicholas M. Hurren ◽  
Frank F. Eves ◽  
Andrew K. Blannin
Keyword(s):  
Test Meal ◽  
Venous Blood ◽  
Exercise Bout ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Postprandial Lipaemia ◽  
Fasted State ◽  
Prior Exercise ◽  
Fat Meal

Moderate-intensity exercise can lower the TAG response to a high-fat meal; however, the British diet is moderate in fat, and no study to date has compared the effect of such exercise on responses to high-fat and moderate-fat meals. The present work investigated the effect of brisk walking performed 13 h before intake of both high-fat and moderate-fat meals on postprandial plasma TAG concentrations. Eight inactive, overweight men completed four separate 2 d trials, i.e. rest (Con) or a 90-min treadmill walk (Ex) on the evening of day 1, followed by the ingestion of a moderate-fat (Mod) or high-fat (High) meal on the morning of day 2. High-fat meals contained 66 % of total energy as fat, while the percentage was 35 % for moderate-fat meals; both the meals were, however, isoenergetic. On day 2, venous blood was sampled in the fasted state, 30 and 60 min after ingesting the test meal and then hourly until 6 h post-meal. Exercise reduced plasma TAG concentrations significantly (P < 0·001), with no exercise × meal interaction (P = 0·459). Walking reduced the total TAG response to a high-fat meal by 29 % (relative to High Con); the same bout of exercise performed before ingesting a moderate-fat meal lowered total TAG by 26 % (compared with Mod Con). The ability of a single moderate-intensity aerobic exercise bout to lower postprandial TAG concentrations is just as great, in percentage terms, when the test meal ingested is of a moderate rather than a high fat content.

scholarly journals Tai-Chi-Chuan Exercise Improves Pulmonary Function and Decreases Exhaled Nitric Oxide Level in Both Asthmatic and Nonasthmatic Children and Improves Quality of Life in Children with Asthma

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Hsin-Chia Lin ◽  
Hao-Pai Lin ◽  
Hsin-Hui Yu ◽  
Li-Chieh Wang ◽  
Jyh-Hong Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nitric Oxide ◽  
Pulmonary Function ◽  
Airway Inflammation ◽  
Tai Chi ◽  
Exhaled Nitric Oxide ◽  
Moderate Intensity ◽  
Tai Chi Chuan ◽  
Asthmatic Children

Tai-Chi-Chuan (TCC) is an exercise of low-to-moderate intensity which is suitable for asthmatic patients. The aim of our study is to investigate improvements of the lung function, airway inflammation, and quality of life of asthmatic children after TCC. Participants included sixty-one elementary school students and they were divided into asthmatic (n=29) and nonasthmatic (n=32) groups by the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Among them, 20 asthmatic and 18 nonasthmatic children volunteered to participate in a 60-minute TCC exercise weekly for 12 weeks. Baseline and postintervention assessments included forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow rate (PEFR), fractional exhaled nitric oxide (FeNO) level, and Standardised Pediatric Asthma Quality of Life Questionnaire (PAQLQ(S)). After intervention, the level of FeNO decreased significantly; PEFR and the FEV1/FVC also improved significantly in both asthmatic group and nonasthmatic group after TCC. The asthmatic children also had improved quality of life after TCC. The results indicated that TCC could improve the pulmonary function and decrease airway inflammation in both children with mild asthma and those without asthma. It also improves quality of life in mild asthmatic children. Nevertheless, further studies are required to determine the effect of TCC on children with moderate-to-severe asthma.

High-intensity exercise attenuates postprandial lipaemia and markers of oxidative stress

2012 ◽  
Vol 123 (5) ◽  
pp. 313-321 ◽  
Author(s):  
Brendan Gabriel ◽  
Aivaras Ratkevicius ◽  
Patrick Gray ◽  
Michael P. Frenneaux ◽  
Stuart R. Gray
Keyword(s):  
Oxidative Stress ◽  
Adhesion Molecule ◽  
High Intensity ◽  
Intermittent Exercise ◽  
Protein Carbonyls ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Markers Of Oxidative Stress ◽  
Fat Meal

Regular exercise can reduce the risk of CVD (cardiovascular disease). Although moderate-intensity exercise can attenuate postprandial TAG (triacylglycerol), high-intensity intermittent exercise might be a more effective method to improve health. We compared the effects of high-intensity intermittent exercise and 30 min of brisk walking on postprandial TAG, soluble adhesion molecules and markers of oxidative stress. Nine men each completed three 2-day trials. On day 1, subjects rested (control), walked briskly for 30 min (walking) or performed 5×30 s maximal sprints (high-intensity). On day 2, subjects consumed a high-fat meal for breakfast and 3 h later for lunch. Blood samples were taken at various times and analysed for TAG, glucose, insulin, ICAM-1 (intracellular adhesion molecule-1), VCAM-1 (vascular adhesion molecule-1), TBARS (thiobarbituric acid- reactive substances), protein carbonyls and β-hydroxybutyrate. On day 2 of the high-intensity trial, there was a lower (P<0.05) incremental TAG AUC (area under the curve; 6.42±2.24 mmol/l per 7 h) compared with the control trial (9.68±4.77 mmol/l per 7 h) with no differences during day 2 of the walking trial (8.98±2.84 mmol/l per 7 h). A trend (P=0.056) for a reduced total TAG AUC was also seen during the high-intensity trial (14.13±2.83 mmol/l per 7 h) compared with control (17.18±3.92 mmol/l per 7 h), walking showed no difference (16.33±3.51 mmol/l per 7 h). On day 2 of the high-intensity trial plasma TBARS and protein carbonyls were also reduced (P<0.05) when compared with the control and walking trials. In conclusion, high-intensity intermittent exercise attenuates postprandial TAG and markers of oxidative stress after the consumption of a high-fat meal.

scholarly journals Effects of an acute bout of moderate-intensity exercise on postprandial lipemia and airway inflammation

2016 ◽  
Vol 41 (3) ◽  
pp. 284-291 ◽  
Author(s):  
Ariel M. Johnson ◽  
Stephanie P. Kurti ◽  
Joshua R. Smith ◽  
Sara K. Rosenkranz ◽  
Craig A. Harms
Keyword(s):  
Airway Inflammation ◽  
Systemic Inflammation ◽  
Inflammatory Markers ◽  
Acute Exercise ◽  
Postprandial Lipemia ◽  
Lipid Lowering ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Acute Bout ◽  
Old Men

A high-fat meal (HFM) induces an increase in blood lipids (postprandial lipemia; PPL), systemic inflammation, and acute airway inflammation. While acute exercise has been shown to have anti-inflammatory and lipid-lowering effects, it is unknown whether exercise prior to an HFM will translate to reduced airway inflammation post-HFM. Our purpose was to determine the effects of an acute bout of exercise on airway inflammation post-HFM and to identify whether any protective effect of exercise on airway inflammation was associated with a reduction in PPL or systemic inflammation. In a randomized cross-over study, 12 healthy, 18- to 29-year-old men (age, 23.0 ± 3.2 years; height, 178.9 ± 5.5 cm; weight, 78.5 ± 11.7 kg) consumed an HFM (1 g fat/1 kg body weight) 12 h following exercise (EX; 60 min at 60% maximal oxygen uptake) or without exercise (CON). Fractional exhaled nitric oxide (FENO; measure of airway inflammation), triglycerides (TG), and inflammatory markers (high-sensitivity C-reactive protein, tumor-necrosis factor-alpha, and interleukin-6) were measured while fasted at 2 h and 4 h post-HFM. FENOincreased over time (2 h: CON, p = 0.001; EX, p = 0.002, but not by condition (p = 0.991). TG significantly increased 2 and 4 h post-HFM (p < 0.001), but was not significant between conditions (p = 0.256). Inflammatory markers did not significantly increase by time or condition (p > 0.05). There were no relationships between FENOand TG or systemic inflammatory markers for any time point or condition (p > 0.05). In summary, an acute bout of moderate-intensity exercise performed 12 h prior to an HFM did not change postprandial airway inflammation or lipemia in healthy, 18- to 29-year-old men.

Aerobic Exercise Improves Postprandial Inflammatory and Hemostatic Markers After a High-Fat Meal: A Randomized Cross-Over Study

2020 ◽  
Author(s):  
Bruno Costa Teixeira ◽  
Renata L. Krüger ◽  
Juliano Boufleur Farinha ◽  
Francesco P Boeno ◽  
Rodrigo Cauduro Oliveira Macedo ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Exercise Intensity ◽  
Inflammatory Markers ◽  
Factor Vii ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Postprandial State ◽  
Anti Inflammatory ◽  
Fat Meal

Exercise intensity modulates postprandial lipemia. It is still unknown, however, its effect on hemostatic and pro- and anti-inflammatory markers in the postprandial state. Eleven young males perform a 2-day trial on different conditions: (i) REST: rest for 45 min; (ii) MIE: moderate-intensity exercise; and (iii) HIE: heavy-intensity exercise. Experimental conditions were performed in the evening. On the following morning, blood samples were taken in the fasted state (0 h) and at 1, 3, and 5 h after the consumption of a high-fat meal (HFM). Interleukin-10 (IL-10) levels were higher in the HIE vs. MIE trial at 0 and 1 h (p < 0.033) and IL-10 iAUC was greater in the MIE (p = 0.027) and HIE (p = 0.045) vs. REST. Lower levels of anti-coagulation factor VII (FVII) were observed at 1 h in the MIE condition vs. REST (p = 0.043). In comparison with REST, MIE improved hemostatic (FVII) and anti-inflammatory markers (IL-10 iAUC) whereas HIE enhanced IL-10 in the postprandial state. Regardless of the exercise intensity, aerobic exercise mitigates the deleterious consequences of an HFM. Novelty Bullets: • Prior aerobic exercise at moderate-intensity attenuates next day’s postprandial FVII and IL-10 levels whereas exercise performed at heavy-intensity increases IL-10 levels. • Moderate-intensity exercise may be more beneficial to improve hemostatic (FVII) and anti-inflammatory (IL-10) responses while heavy-intensity exercise may improve anti-inflammatory (IL-10) levels only.

scholarly journals Does chronic physical activity level modify the airway inflammatory response to an acute bout of exercise in the postprandial period?

2017 ◽  
Vol 42 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Stephanie P. Kurti ◽  
Sara K. Rosenkranz ◽  
Stephen K. Chapes ◽  
Colby S. Teeman ◽  
Brooke J. Cull ◽  
...  
Keyword(s):  
Physical Activity ◽  
Inflammatory Response ◽  
Oxygen Uptake ◽  
Airway Inflammation ◽  
Peak Oxygen Uptake ◽  
Activity Level ◽  
Postprandial Period ◽  
Acute Bout ◽  
Cell Counts ◽  
Ex Post

Recent studies have confirmed that a single high-fat meal (HFM) leads to increased airway inflammation. However, exercise is a natural anti-inflammatory and may modify postprandial airway inflammation. The postprandial airway inflammatory response is likely to be modified by chronic physical activity (PA) level. This study investigated whether chronic PA modifies the airway inflammatory response to an acute bout of exercise in the postprandial period in both insufficiently active and active subjects. Thirty-nine nonasthmatic subjects (20 active, 13 males/7 females) who exceeded PA guidelines (≥150 min moderate−vigorous PA/week) and 19 insufficiently active (6 males/13 females) underwent an incremental treadmill test to exhaustion to determine peak oxygen uptake. Subjects were then randomized to a condition (COND), either remaining sedentary (CON) or exercising (EX) post-HFM. Exercise was performed at the heart rate corresponding to 60% peak oxygen uptake on a treadmill for 1 h post-HFM (63% fat, 10 kcal/kg body weight). Blood lipids and exhaled nitric oxide (eNO: marker of airway inflammation) were measured at baseline and 2 h and 4 h post-HFM. Sputum differential cell counts were performed at baseline and 4 h post-HFM. The mean eNO response for all groups increased at 2 h post-HFM (∼6%) and returned to baseline by 4 h (p = 0.03). There was a time × COND interaction (p = 0.04), where EX had a greater eNO response at 4 h compared with CON. Sputum neutrophils increased at 4 h post-HFM (p < 0.05). These findings suggest that airway inflammation occurs after an HFM when exercise is performed in the postprandial period, regardless of habitual activity level.

Effects of an Acute Bout of Moderate Intensity Exercise on Airway Inflammation and Postprandial Lipemia

2014 ◽  
Vol 46 ◽  
pp. 10
Author(s):  
Ariel M. Johnson ◽  
Stephanie P. Kurti ◽  
Joshua R. Smith ◽  
Sara K. Rosenkranz ◽  
Craig A. Harms
Keyword(s):  
Airway Inflammation ◽  
Postprandial Lipemia ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Acute Bout
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