scholarly journals Isoflavones Reduce Copper with Minimal Impact on IronIn Vitro

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Jana Karlíčková ◽  
Kateřina Macáková ◽  
Michal Říha ◽  
Liliane Maria Teixeira Pinheiro ◽  
Tomáš Filipský ◽  
...  

Isoflavones are commonly consumed in many Asian countries and have potentially positive effects on human being. Only a few and rather controversial data on their interactions with copper and iron are available to date. 13 structurally related isoflavones were tested in the competitive manner for their Cu/Fe-chelating/reducing properties. Notwithstanding the 5-hydroxy-4-keto chelation site was associated with ferric, ferrous, and cupric chelation, the chelation potential of isoflavones was low and no cuprous chelation was observed. None of isoflavones was able to substantially reduce ferric ions, but the vast majority reduced cupric ions. The most important feature for cupric reduction was the presence of an unsubstituted 4′-hydroxyl; contrarily the presence of a free 5-hydroxyl decreased or abolished the reduction due to chelation of cupric ions. The results from this study may enable additional experiments which might clarify the effects of isoflavones on human being and/or mechanisms of copper absorption.

2014 ◽  
Vol 33 (3) ◽  
pp. 25-34
Author(s):  
Peter Ponický ◽  
Vítězslav Zamarský

Nowadays, innovation is perhaps the most widely spoken global keyword in the field of economy. Everyone talks about innovation and the European Union already for more than a decade, has wanted through innovation to catch up with and take the leading position in the world. However, what is the reality? Europe still has difficulties with the pace of economic growth, which according to many is joined combined with innovation and knowledge. Asian countries often set a price of an innovated product of poor quality and with no added value that includes huge cost of efficient marketing and aggressive advertising. Therefore, is innovation everything what is called this way? Though the world controls the speed and acceleration of changes, it does not mean necessarily an advantage or positive effects. And evolution of a star in a supernova and then a black hole is in the final stages accelerated in an unusual way. The inspiration for our article was slanted to cheap using the word “innovation”, just because it is a European priority. We just drew from his knowledge and life experiences.


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17074-17074
Author(s):  
B. Koczwara ◽  
S. Ackland ◽  
A. Esterman ◽  
F. Marine ◽  
M. Stockler ◽  
...  

17074 Background: ACORD is a 1-week, intensive educational workshop designed to increase skills of junior cancer clinical researchers from the Asia Pacific region. Participants come from region of diverse cultures, languages and resources. Methods: We surveyed participants 1 year after the workshop to determine its impact on their research output. Participants were grouped into those from: Australia or New Zealand (ANZ), developed Asian countries (Japan, Korea, Taiwan), and developing Asian countries (India, China, Bangladesh, Philippines, Indonesia, Malaysia). Results: The response rate was higher from developed Asia (10/10, 100%), than ANZ (44/59, 75%) and developing Asia (7/12, 58%). The proportion of respondents spending more than half of their time in research was higher in ANZ (21%), than developing Asia (14%) or developed Asia (10%). The workshop was rated very valuable by more respondents from developing Asia (71%) than from ANZ (59%) and developed Asia (60%). More than half of respondents had submitted their ACORD protocol to an IRB. Progress activating protocols was reported more frequently by respondents from developing Asia (86%) than developed Asia (70%) and ANZ (59%). Involvement in other research was also reported more frequently by respondents from developing Asia (100%) than ANZ (82%) or developed Asia (80%). The most frequently reported barriers to progressing research were: other work commitments (71% for developing Asia, 44% for ANZ, 30% for developed Asia) and lack of funding (71% for developing Asia, 39% for ANZ, and 33% for developed Asia). Continuing contact with faculty and participants was reported more frequently by respondents from ANZ (59%), than developed Asia (43%) or developing Asia (30%). Conclusions: Respondents were highly satisfied with the workshop, perceiving positive effects on their research skills and careers. Participants from developing countries were more likely to take their protocols forward, despite reporting greater barriers to progress, and less continuing contact with faculty and participants. Protected time and support for researchers are worth considering for developing countries wanting to improve their research output. [Table: see text]


2018 ◽  
Vol 1 (2) ◽  
pp. 55
Author(s):  
Hani Sirine ◽  
Elisabeth Penti Kurniawati

Human being as spiritual being needs to be nurtured spiritually so that they can be optimal in their work and their calling. Actualization of this calling can be made through entrepreneurship. The purpose of this study is to determine the importance of spiritual dimensions (vision, faith/hope, love altruistic, meaning/calling, membership) in the development of entrepreneurship (entrepreneurship intention, entrepreneurial networking, entrepreneurial capability, and entrepreneurial success). The analysis technique of this study uses multiple linear regressions with a sample of 67 graduates of Universitas Kristen Satya Wacana (UKSW) who have had and run their own business. The results show that the spirituality dimensions (vision, faith/hope, altruistic love, meaning/calling, membership) significantly influence entrepreneurial intention, entrepreneurial networking, entrepreneurial capability, and entrepreneurial success. When it is tested partially, the significant positive effect on entrepreneurial intention is vision and faith/hope. Faith/hope also has significant positive effects on entrepreneurial networking. Vision, faith/hope, and meaning/calling has significant positive effects on entrepreneurial capabilities. Lastly, faith/hope, and meaning/calling has significant positive effects on entrepreneurial success.


2020 ◽  
Vol 37 (1) ◽  
pp. 103-112
Author(s):  
Zehra Torun ◽  
Belma Konuklugil

Macroalgae are seaweeds, which are often consumed as much as food in Asian countries. Studies have been made that carbohydrate compounds such as oligosaccharides and polysaccharides can be considered as prebiotics. Prebiotics are nutrient sources of probiotics that defined as useful microorganisms in the gastrointestinal tract especially. With the positive effects of prebiotics on probiotics, the gastointestinal system and thus all body systems are kept in a healthy balance. This review provides brief information about probiotics, prebiotics and is a pioneer in the studies on the evaluation of macroalgae as prebiotics in our country.


2020 ◽  
Author(s):  
James F. Markworth ◽  
Lemuel A. Brown ◽  
Eunice Lim ◽  
Jesus A. Castor-Macias ◽  
Jacqueline Larouche ◽  
...  

AbstractChronic inflammation and deregulated acute immune cell responses to injury contribute to age-associated skeletal muscle dysfunction. Specialized pro-resolving mediators (SPMs) control inflammation and support myofiber regeneration in young mice, but their role in aging muscle remains unknown. Here we examined the effect of age on the mediator lipidome of skeletal muscle via LC-MS based lipidomic profiling and tested whether systemic administration of the SPM resolvin D1 (RvD1) could limit excessive inflammation and improve the regenerative capacity of aged muscle. Aged mice displayed chronic low-grade muscle inflammation prior to injury and this was associated with a basal deficiency of lipoxygenase (LOX) derived SPMs as well as anti-inflammatory cytochrome P450 (CYP) derived lipid epoxides. Following muscle damage, young and aged mice produced similar amounts of pro-inflammatory cyclooxygenase (COX) and 12-LOX metabolites, but aged mice mounted a markedly deficient SPM response. This was associated with heightened leukocyte recruitment, impaired myofiber regeneration, and delayed recovery of strength. Systemic treatment with RvD1 had minimal impact on excessive myeloid cell infiltration and defective myofiber regeneration in aged mice. Nevertheless, RvD1 treatment did suppress inflammatory cytokines, modulated muscle stem cells, limited maladaptive tissue remodeling, and improved recovery of specific muscle force. We conclude that aging results in a marked deficiency of local SPM biosynthesis within muscle and that immunoresolvents may be attractive novel therapeutics for the treatment of muscular injuries and associated pain in the elderly, due to positive effects on recovery of muscle function without the negative side effects on myofiber regeneration of traditional anti-inflammatory treatments.


2021 ◽  
Vol 12 (47) ◽  
pp. 132-137
Author(s):  
José Ricardo Mariano ◽  
Jhonata Teixeira de Lima ◽  
Hugo Eduardo de Miranda Peixoto ◽  
João Paulo Lyra e Silva

More and more patients seek differentiated treatments, which value the human being and bring him well being. In this context, the demand for alternative therapies that value nature, the human being and the energies present in each organism has grown. There are some possible reasons why music can produce positive effects on health, such as: music is ubiquitous, emotional, involving, distracting, generates a physical demand, is ambiguous, social, communicative, affects behavior and identity. This systematic review an overview of music therapy as an alternative that can be used in the dental office with anxiety control as the benefit of this practice.


2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Takumi Ogino ◽  
Takuya Uehara ◽  
Masahiko Muraji ◽  
Terumi Yamaguchi ◽  
Takahisa Ichihashi ◽  
...  

AbstractThe predatory bug Orius sauteri is an indigenous natural enemy of thrips and whiteflies in Asian countries. To put these bugs to practical use in pest management, methods to attract and retain the bugs in agricultural fields are needed. We previously showed that violet light (405 nm) attracts O. sauteri selectively. Many thrips and whiteflies are attracted to UV or green light. In this study, we examined the effect of violet-LED illumination on O. sauteri in pesticide-free eggplant (Solanum melongena L.) cultivation. In three cultivation trials, the density of O. sauteri on eggplant leaves was consistently higher in the illuminated plots; at least twice that of the non-illuminated plots. Simultaneously, the density of thrips declined markedly to less than half that of the non-illuminated plots. We identified three positive effects of violet light including an “immediate-effect” on predator attraction, a “persistent-effect” on predator reproduction, and a “secondary-effect” on the food web structure. Our results showed that illumination with violet light provides a powerful tool for integrated pest management. This is the first report on the use of illumination to manipulate the behavior of natural enemies.


2019 ◽  
Vol 46 (6) ◽  
pp. 822-837
Author(s):  
Samina Sabir ◽  
Meshal Qamar

Purpose The purpose of this paper is to examine the impact of fiscal policy and institutional quality on the inclusive growth process of the selected developing Asian countries. Inclusive growth is a growth process which ensures that everyone is participating and benefited by growth process. Design/methodology/approach This study uses system generalized method of moment to address the problem of endogeneity and omitted variable bias. Findings Empirical results showed that both fiscal policy and institutions have positive effects on inclusive growth. Our empirical results confirmed that fiscal policy can work more efficiently in the presence of good quality institutions in the developing Asian countries. Research limitations/implications Government should take measures to improve infrastructure, roads and transport system, and main share of government expenditures should be allocated to development, education and health projects. There is a need to transform the tax structure of the countries with the huge emphasis on the progressive tax system and this is likely to benefit the lower segment of the population. There is a need to develop institutions as they serve as a road map for the development of a country. There should be coordination between government policies and institutions. Supervision of fiscal policy through good institutions is needed for the proper allocation and utilization of public resources. Practical implications By restructuring the taxation system subject to the provision of quality institutions, government can incentivize entrepreneurs to make significant investments. This creates jobs for lower segment of a society, brings down poverty and increases the income level of a country. This increases the individual and collective welfare of an economy that ensures the inclusive growth within a country. Originality/value In this study, proxies used for fiscal policy are government expenditures and tax revenues as a percentage of gross domestic product (GDP) to examine its impact on the certain measures of inclusive growth such as employment, income inequality and GDP per capita. This study provides useful insights for the policy makers using fiscal policy to achieve the goal of inclusive growth in developing countries.


2013 ◽  
pp. 198-207
Author(s):  
K. C. Prakash

Right to life is a phrase that describes the belief that a human being has an essential right to live, particularly that a human being has the right not to be killed by another human being. The concept of right to life is central to debates on the issues of capital pun ishment, self defense, abortion and war. Pro-life is a term representing a variety of perspectives and activist movements in medical ethics. It is most commonly used, especially in the media and popular discourse, to refer to opposition to abortion. More generally, the term describes a political and ethical view which maintains that human fetuses and embryos are persons and therefore have a right to live. Less commonly, it can be used to indicate abortion. Right to life is based on three things as food, clo th and shelter.


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