scholarly journals Surgical Excision of Orbital Progressive Granular Cell Tumour

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Demetrio Germanò ◽  
Hossein Mostafa Elbadawy ◽  
Diego Ponzin ◽  
Daniele Ferro ◽  
Leonardo Priore

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.

2020 ◽  
pp. 1-2
Author(s):  
Sabari Devi ◽  
Waziha Ahmed

Congenital granular cell tumour/ epulis (CGCE) is a rare benign lesion of the newborn. It was first described in 1871 by Neumann. It usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. The exact histogenesis is unclear. The proposed source of origin includes undifferentiated mesenchymal cells, odontogenic epithelial, pericytes, fibroblasts, smooth muscle cells. Treatment involves surgical excision and and its curative with rare recurrence rate.


2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.


1970 ◽  
Vol 1 (2) ◽  
pp. 161-163
Author(s):  
R Baidya ◽  
B Sigdel ◽  
NL Baidya ◽  
S Chakraborti

A granular cell tumor is an unusual benign soft tissue neoplasm, occurring in the tongue, oral cavity or subcutaneous tissue and rarely occurs in the breast. We report a case of 44 years old male, who presented with a swelling in the right breast since 7 years measuring 6 x 4 cm. Fine needle aspiration cytology was suggestive of low grade carcinoma and on histopathologic examination, it was diagnosed as granular cell tumour, with S-100 immunopositivity.   Keywords: Granular cell tumour; Male breast; S-100 DOI: http://dx.doi.org/10.3126/jpn.v1i2.5414 JPN 2011; 1(2): 161-163


Author(s):  
arpita singh ◽  
Snehashish Ghosh ◽  
Anjani Yadav ◽  
Anuja Panthee

Congenital Granular Cell Tumour (CGCT) is a rare benign lesion and presents in newborn as fibrous mass arising from the alveolus.The prenatal screening of lesion can help in parent counselling, determining the complications, as larger size lesion may interfere with normal delivery and require caesarean section.


1970 ◽  
Vol 3 (1) ◽  
pp. 28-30
Author(s):  
SM Khodeza ◽  
Nahar Begum ◽  
Nishat Begum

Vulvar granular cell tumours are uncommon neoplasms of neural origin. The clinical presentations, surgical findings and histology of Granular Cell Tumour (GCT) of the vulva in a 50 year old lady is presented. Although rare, this benign lesion must be considered in the differential diagnosis of the labia majora masses, such as Bartholin,s duct cyst, Lipoma, Papilloma, Hydradenoma and Fibroma. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10111 AKMMCJ 2012; 3(1): 28-30


2006 ◽  
Vol 121 (2) ◽  
pp. 170-173 ◽  
Author(s):  
T Sasaki ◽  
K Yamamoto ◽  
T Akashi

An extremely rare case of a granular cell tumour arising from the right Kiesselbach's area (Little's area) of the nasal septum is reported. A 69-year-old Japanese woman consulted our clinic and her chief complaints were of continuous serous discharge, stuffiness and occasional slight bleeding from the right nasal cavity. Fibrescopy showed a multilocular mass, which was provisionally considered a nasal polyp. Surgical excision was attempted. During surgery, the tumour shrank markedly following local application of adrenaline, suggestive of hypervascularity. The tumour was successfully excised by careful dissection after cauterisation of the mucosa surrounding the tumour. Histopathological examination revealed morphological features of granular cell tumour immunopositive for S-100 protein. This is the first report of granular cell tumour arising from the Kiesselbach's area in the English literature. The eccentric behaviour of the tumour and the management of a granular cell tumour arising from this area are discussed, together with a literature review.


1994 ◽  
Vol 8 (2) ◽  
pp. 92-96
Author(s):  
F Schweiger ◽  
J Radhi ◽  
FW Coop ◽  
RW Murphy

Granular cell tumour of the extrahepatic biliary tract is a rare benign lesion likely of neurogenic origin. Review of the previously reported cases indicates that almost all patients are female, and the majority is Black. Symptoms usually are those of biliary obstruction or cholecystitis. Surgical resection of the tumour is curative. Intrahepatic bile duct adenoma is another rare benign biliary neoplasm that does not manifest clinically but can be confused with metastatic carcinoma, cholangiocarcinoma or other focal liver lesions at laparotomy or autopsy. The authors report the case of an asymptomatic Caucasian woman with biochemical evidence of liver disease who had a granular cell tumour of the bile duct as well as several intrahepatic bile duct adenomas.


2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Sarah Bouayyad ◽  
Jen Ong ◽  
Houda Bouayyad ◽  
Heerani Woodun

Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.


2019 ◽  
Vol 9 (1) ◽  
pp. 46-50
Author(s):  
E.B. Edetanlen ◽  
C.B. Ogboh

Congenital granular cell tumour of the new born is a rare benign lesion of soft tissues which normally affects the maxillary alveolar ridge in neonates. Though benign, it can cause respiratory embarrassment and prevent feeding causing physical distress to the infant and psychological distress to the parents or guardian. Very few cases are reported in the literature. We aimed to highlight the clinical presentation, management and a brief review of the literature of the lesion.A case of a 3-day old baby who presented to the Oral and Maxillofacial Surgery Clinic University of Benin Teaching Hospital (UBTH) was used to illustrate the clinical presentation and management of congenital epulis.Congenital epulis of the new-born is a rare occurrence, though it can grow to a frightening size, it still remains a benign lesion with li le or no recurrence following surgical excision. The role of counselling to the parents cannot be over-emphasized.Keywords: Congenital, epulis, granular, newborn


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