scholarly journals Prenatal Diagnosis of Cardiac Diverticulum with Pericardial Effusion in the First Trimester of Pregnancy with Resolution after Early Pericardiocentesis

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Raquel Garcia Rodriguez ◽  
Azahara Rodriguez Guedes ◽  
Raquel Garcia Delgado ◽  
Lourdes Roldan Gutierrez ◽  
Margarita Medina Castellano ◽  
...  

Cardiac diverticulum is a rare anomaly, which may present in association with pericardial effusion. Only few cases diagnosed during fetal life have been published and only in 12 cases pericardiocentesis was made with good postnatal outcomes in 83% of the cases. In the first trimester of pregnancy only 6 cases were reported. We described the largest series of cases published. We describe a case of cardiac diverticulum complicated with pericardial effusion during the first trimester of pregnancy and resolved by intrauterine pericardiocentesis at 17 weeks of pregnancy. We made a systematic review of the literature with the cases reported of cardiac diverticulum, management, and outcomes.

2017 ◽  
Vol 2017 ◽  
pp. 1-9
Author(s):  
Raquel Garcia Rodriguez ◽  
Azahara Rodriguez Guedes ◽  
Raquel Garcia Delgado ◽  
Lourdes Roldan Gutierrez ◽  
Margarita Medina Castellano ◽  
...  

2020 ◽  
Vol 26 (7) ◽  
pp. 971-973 ◽  
Author(s):  
Melissa H Rosen ◽  
Jordan Axelrad ◽  
David Hudesman ◽  
David T Rubin ◽  
Shannon Chang

Abstract First detected in Wuhan, China, the novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped RNA beta-coronavirus responsible for an unprecedented, worldwide pandemic caused by COVID-19. Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 infection currently is based on expert opinion, given the novelty of the infection and the corresponding lack of high-level evidence in patients with immune-mediated conditions. There are limited data regarding IBD patients with COVID-19 and no data regarding early pregnancy in the era of COVID-19. This article describes a patient with acute severe ulcerative colitis (UC) during her first trimester of pregnancy who also has COVID-19. The case presentation is followed by a review of the literature to date on COVID-19 in regard to inflammatory bowel disease and pregnancy, respectively.


2006 ◽  
Vol 28 (4) ◽  
pp. 534-534
Author(s):  
I. Korkontzelos ◽  
A. Tsirka ◽  
P. Tsirkas ◽  
P. Diamantopoulos ◽  
A. Zagaliki ◽  
...  

2020 ◽  
Vol 32 (2) ◽  
pp. 230
Author(s):  
S. Succu ◽  
S. Sale ◽  
G. Ghirello ◽  
J. Ireland ◽  
A. Evans ◽  
...  

The causes of the inherently high variation in number of follicles and oocytes in ovaries of mammals are unknown. Evidence suggests that the ovarian reserve (total number of healthy follicles and oocytes in ovaries) can be programmed by events occurring during fetal life. For instance, maternal nutritional restriction during the first trimester of pregnancy negatively affects the size of the ovarian reserve in calves. The aim of the present study was to establish whether exposure of pregnant dairy cows to high environmental temperatures from conception to the end of the first trimester of pregnancy impairs establishment of the ovarian reserve in their offspring. This work was conducted in four commercial dairy farms with similar nutrition and farming systems located in Sardinia, Italy, on a total of 310 Holstein-Friesian dairy heifers (16 months old) that were conceived and born at different times of year coincident with different environmental temperatures. We tested whether exposure of the heifer's dams to a mean temperature-humidity index (THI) >68 from conception to the end of the first trimester of pregnancy resulted in a diminished ovarian reserve in their offspring. To estimate the size of the ovarian reserve, a single blood sample was collected to measure serum anti-Müllerian hormone (AMH; n=310), and the number of follicles >3mm (antral follicle count, AFC) was assessed using transrectal ovarian ultrasonography (n=258) on a random day of the oestrous cycle (16.09±0.07 months of age). Relations among variables were analysed with Pearson correlation with SAS (SAS Institute Inc.). Anti-Müllerian hormone and AFC were analysed with a mixed model (PROC MIXED of SAS) considering the main effects of season during the first trimester of fetal life and age at sampling; the effect of farm was included as a random effect. Tukey's test was used for comparisons. Circulating AMH concentrations and AFC were highly positively correlated (P<0.0001), as previously reported. The results also showed that both AMH concentrations and AFC were lower (419.27±22.81 pgmL−1, 9.32±0.42 follicles; P<0.0001) in young adult heifers of the dams exposed to a THI >68 compared with dams exposed to an average THI of 55 (634.91±47.60 pgmL−1, 11.84±0.46 follicles). Neither AMH nor AFC were influenced by farm and age at sampling of the daughters. In conclusion, maternal exposure to THI >68 (typical high temperatures during summers in Sardinia) during the first trimester of pregnancy has a negative effect on the development of the ovarian reserve in female fetuses, which may subsequently impair their reproductive performance as adults. Research was funded by Regione Autonoma della Sardegna, Legge Regionale 7, Bando 2015.


2016 ◽  
Vol 6 (1) ◽  
pp. 31-36
Author(s):  
Katarzyna Pośpiech-Gąsior ◽  
Maciej Słodki ◽  
Maria Respondek-Liberska

Abstract Cantrell’s pentalogy is a congenital defect characterized by uncompleted fusion of the anterior chest wall, resulting in an extrathoracic location of the heart. Ultrasound diagnosis during the first trimester of prenatal life is possible, and termination of pregnancy is usually chosen by pregnant women. We analysed 57 fetuses: 56 from literature and one additional recent case from our institute (from 2016) to evaluate what was the survival rate reported after prenatal diagnosis, including the possibility to terminate the pregnancy, intrauterine deaths and neonatal deaths. We found 10 survivors - 18% since 1984. Despite dismal prognosis of fetal ectopia cordis, there is a chance for postnatal survivorship probably due to evolving anatomical structures, not only in the first trimester of pregnancy but also during the following weeks of prenatal life.


2001 ◽  
Vol 21 (13) ◽  
pp. 1129-1132 ◽  
Author(s):  
M. V. Senat ◽  
J. P. Bernard ◽  
A. Delezoide ◽  
P. Saugier-Veber ◽  
Y. Hillion ◽  
...  

2020 ◽  
Vol 22 (2) ◽  
pp. 189 ◽  
Author(s):  
Mihaela Grigore ◽  
Romeo Micu ◽  
Roxana Matasariu ◽  
Odetta Duma ◽  
Anca Lucia Chicea ◽  
...  

Pentalogy of Cantrell (POC) is a rare condition characterized by complete or partial expression of 5 types of congenital birth defects originating in (1) the lower sternum, (2) the anterior diaphragm, (3) the diaphragmatic pericardium, (4) the midline/ventral supraumbilical abdominal wall region, and (5) the heart. POC can be diagnosed antenatally by means of ultrasonography (US), the task being difficult if defects are minor. Advances in the field of US and the introduction of the first morphology trimester as state-of-the-art pregnancy monitoring, facilitate the early diagnosis of this condition. We performed a systematic review on 67 reported cases of POC diagnosed in the first trimester of pregnancy (published from January 1980 to July 2019). The aim of our systematic review was twofold: to assess the main US findings in the first trimester of pregnancy and to increase awareness of early diagnostic possibilities. Our study showed that POC can be diagnosed in the first trimesterof pregnancy based on key US findings such as the association between omphalocele and ectopia cordis. When these two anomalies are present, increased nuchal translucency can also be considered a marker of POC in the first trimester.


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