scholarly journals A Computational Model to Assess Poststenting Wall Stresses Dependence on Plaque Structure and Stenosis Severity in Coronary Artery

2014 ◽  
Vol 2014 ◽  
pp. 1-12
Author(s):  
Zuned Hajiali ◽  
Mahsa Dabagh ◽  
Payman Jalali

The current study presents computational models to investigate the poststenting hemodynamic stresses and internal stresses over/within the diseased walls of coronary arteries which are in different states of atherosclerotic plaque. The finite element method is applied to build the axisymmetric models which include the plaque, arterial wall, and stent struts. The study takes into account the mechanical effects of the opening pressure and its association with the plaque severity and the morphology. The wall shear stresses and the von Mises stresses within the stented coronary arteries show their strong dependence on the plaque structure, particularly the fibrous cap thickness. Higher stresses occur in severely stenosed coronaries with a thinner fibrous cap. Large stress concentrations around the stent struts cause injury or damage to the vessel wall which is linked to the mechanism of restenosis. The in-stent restenosis rate is also highly dependent on the opening pressure, to the extent that stenosed artery is expanded, and geometry of the stent struts. The present study demonstrates, for the first time, that the restenosis is to be viewed as a consequence of biomechanical design of a stent repeating unit, the opening pressure, and the severity and morphology of the plaque.

2013 ◽  
Vol 41 (2) ◽  
pp. 127-151
Author(s):  
Rudolf F. Bauer

ABSTRACT The benefits of a tire's equilibrium profile have been suggested by several authors in the published literature, and mathematical procedures were developed that represented well the behavior of bias ply tires. However, for modern belted radial ply tires, and particularly those with a lower aspect ratio, the tire constructions are much more complicated and pose new problems for a mathematical analysis. Solutions to these problems are presented in this paper, and for a modern radial touring tire the equilibrium profile was calculated together with the mold profile to produce such tires. Some construction modifications were then applied to these tires to render their profiles “nonequilibrium.” Finite element methods were used to analyze for stress concentrations and deformations within all tires that did or did not conform to equilibrium profiles. Finally, tires were built and tested to verify the predictions of these analyses. From the analysis of internal stresses and deformations on inflation and loading and from the actual tire tests, the superior durability of tires with an equilibrium profile was established, and hence it is concluded that an equilibrium profile is a beneficial property of modern belted radial ply tires.


Lubricants ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 36
Author(s):  
Matúš Ranuša ◽  
Markus A. Wimmer ◽  
Spencer Fullam ◽  
Martin Vrbka ◽  
Ivan Křupka

Total knee arthroplasty is on the rise worldwide. Despite its success, revision surgeries are also increasing. According to the American Joint Replacement Registry 2020, 3.3% of revision surgeries are due to wear, and 24.2% are due to mechanical loosening. The combination of shear stresses and wear particles occurring at the bone/implant interface can lead to local osteolysis. Although the shear stresses are partially driven by joint friction, relatively little is known about the evolution of the coefficient of friction (CoF) during a gait cycle in total knee replacement. Here we describe the CoF during a gait cycle and investigate its association with kinematics (slide–roll-ratio), applied load, and relative velocity. The artificial knee was simulated by cobalt–chromium condyle on a flat ultra-high-molecular-weight polyethylene (UHMWPE) tibial plateau, lubricated by either water or proteinaceous solution. We found that the CoF is not a constant but fluctuates between the values close to 0 and 0.15. Cross-correlation suggested that this is primarily an effect of the slide–roll ratio and the contact pressure. There was no difference in the CoF between water and proteinaceous solution. Knowledge about the CoF behavior during a gait cycle will help to increase the accuracy of future computational models of total knee replacement.


2016 ◽  
Vol 11 (10) ◽  
pp. 1779-1790 ◽  
Author(s):  
Guillaume Zahnd ◽  
Jelle Schrauwen ◽  
Antonios Karanasos ◽  
Evelyn Regar ◽  
Wiro Niessen ◽  
...  

1987 ◽  
Vol 109 (3) ◽  
pp. 444-450 ◽  
Author(s):  
L. Houpert ◽  
E. Ioannides ◽  
J. C. Kuypers ◽  
J. Tripp

A recently proposed fatigue life model for rolling bearings has been applied to the study of lifetime reduction under conditions conducive to microspalling. The presence of a spike in the EHD pressure distribution produces large shear stresses localized very close to the surface which may account for early failure. This paper describes a parametric study of the effect of such spikes. Accurate stress fields in the volume are calculated for simulated pressure spikes of different height, width and position relative to a Hertzian pressure distribution, as well as for different lubricant traction coefficients and film thicknesses. Despite the high stress concentrations in the surface layers, reductions in life predicted by the model are modest. Typically, the pressure spike may halve the life, with the implication that subsurface fatigue still dominates. In corroboration of this prediction, preliminary experimental work designed to reproduce microspalling conditions shows that microindents due to overrolling particles are a much more common form of surface damage than microspalling.


1986 ◽  
Vol 108 (4) ◽  
pp. 313-320 ◽  
Author(s):  
D. E. Helling ◽  
A. K. Miller ◽  
M. G. Stout

The multiaxial yield behaviors of 1100-0 aluminum, 70:30 brass, and an overaged 2024 aluminum alloy (2024-T7) have been investigated for a variety of prestress histories involving combinations of normal and shear stresses. Von Mises effective prestrains were in the range of 1.2–32%. Prestress paths were chosen in order to investigate the roles of prestress and prestrain direction on the nature of small-strain offset (ε = 5 × 10−6) yield loci. Particular attention was paid to the directionality, i.e., translation and distortion, of the yield locus. A key result, which was observed in all three materials, was that the final direction of the prestrain path strongly influences the distortions of the yield loci. Differences in the yield locus behavior of the three materials were also observed: brass and the 2024-T7 alloy showed more severe distortions of the yield locus and a longer memory of their entire prestrain history than the 1100-0 aluminum. In addition, more “kinematic” translation of the subsequent yield loci was observed in brass and 2024-T7 than in 1100-0 aluminum. The 2024-T7 differed from the other materials, showing a yield locus which decreased in size subsequent to plastic straining. Finally, the implications of these observations for the constitutive modeling of multiaxial material behavior are discussed.


2013 ◽  
Vol 703 ◽  
pp. 200-203
Author(s):  
Shao Biao Cai ◽  
Yong Li Zhao

This study presents a first attempt to develop a numerical three-dimensional multilayered (more than 2 composite layered coatings) elasticperfectly plastic rough solids model to investigate the contact behavior under combined normal loading and tangential traction. Contact analyses are performed to study the effects composite thin film layers. Local contact pressure profiles, von Mises stresses, and shear stresses as a function of material properties and applied normal and tangential friction loads are calculated.


Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Taylor Hoyt ◽  
Jennifer Phipps ◽  
Deborah Vela ◽  
Tianyi Wang ◽  
Maximillian Buja ◽  
...  

Objectives: Intravascular optical coherence tomography (IVOCT) images are recorded by detecting light backscattered within coronary arteries. We hypothesize that non- thin-cap fibroatheroma (TCFA) etiologies may scatter light to create the false appearance of IVOCT TCFA. Background: Conflicting reports are recognized about the accuracy of IVOCT for TCFA detection. Methods: Ten human cadaver hearts were imaged with IVOCT (N=14 arteries). Coronary arteries were sectioned at 120 μm intervals. IVOCT and histologic TCFA were co-registered and compared. Results: Of 21 IVOCT TCFAs identified by two independent IVOCT core labs (fibrous cap <65 μm, lipid arc >90°), only 8 were true histologic TCFA. Foam cell infiltration was responsible for 62% of cases in which either thick-capped fibroatheromas (ThKFAs) appeared like TCFAs or arterial tissue appeared like TCFAs when no lipid core was present. Other false IVOCT TCFA etiologies included SMC-rich fibrous tissue (15%) and loose connective tissue (8%). If the lipid arc >90° criterion was disregarded, 45 IVOCT TCFAs were identified, and sensitivity of IVOCT TCFA detection increased from 53% to 88%; specificity remained high at 93%, and the presence of a new IVOCT image feature called “bright streaks” increased positive predictive value (PPV) to 53%. New mechanisms for light scattering are proposed to explain the low PPV of IVOCT to identify true TCFA (44%), and explain why other plaque components can masquerade as IVOCT TCFA. Conclusions: IVOCT can exhibit up to 88% sensitivity and 98% specificity to detect TCFA, but PPV is limited due to multiple etiologies that cause light scattering similar to true TCFA. Disregarding the lipid arc >90° IVOCT TCFA requirement, and the identification of a new feature, bright steaks, can enhance the ability of IVOCT to detect TCFA. Combining IVOCT with another imaging modality that more specifically recognizes lipid will be important for increasing PPV in the future.


2021 ◽  
Vol 11 (18) ◽  
pp. 8629
Author(s):  
Li-Ren Chang ◽  
Ya-Pei Hou ◽  
Ting-Sheng Lin

The effectiveness of a single four-hole plate (S4HP), perpendicularly oriented four-hole and two-hole plate (Per4H2HP), and perpendicularly oriented double two-hole plate (PerD2HP) for the fixation of a mandibular fracture was studied. A finite element analysis of the mandibular symphysis fractures treated with S4HP, Per4H2HP, and PerD2HP was performed. All surface nodes were fixed in the mandibular condyle region and occlusal muscle forces were applied. The maximal von Mises stress (MaxVMS) values of the plates, screws and screw holes were investigated. The displacement of the fracture site on the lower border of the mandibular symphysis was recorded. The displacement on the lower border of the fracture sites in the S4HP group was greater than that in the Per4H2HP group and the PerD2HP group. There was no eversion at the fracture site among all groups. Both the S4HP and Per4H2HP groups showed stress concentrations on the screws close to the fracture site. The MaxVMS increased when the number of screw holes on the mandibular anterior lower border decreased. The displacement of the fracture site and eversion with Per4H2HP and PerD2HP were far lower than those with S4HP. PerD2HP is a stable and green fixation technique for mandibular symphysis fractures.


2014 ◽  
Vol 136 (11) ◽  
Author(s):  
Jacob T. Munro ◽  
Justin W. Fernandez ◽  
James S. Millar ◽  
Cameron G. Walker ◽  
Donald W. Howie ◽  
...  

Periprosthetic osteolysis in the retroacetabular region with cancellous bone loss is a recognized phenomenon in the long-term follow-up of total hip replacement. The effects on load transfer in the presence of defects are less well known. A validated, patient-specific, 3D finite element (FE) model of the pelvis was used to assess changes in load transfer associated with periprosthetic osteolysis adjacent to a cementless total hip arthroplasty (THA) component. The presence of a cancellous defect significantly increased (p < 0.05) von Mises stress in the cortical bone of the pelvis during walking and a fall onto the side. At loads consistent with single leg stance, this was still less than the predicted yield stress for cortical bone. During higher loads associated with a fall onto the side, highest stress concentrations occurred in the superior and inferior pubic rami and in the anterior column of the acetabulum with larger cancellous defects.


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