scholarly journals Intermittent Alien Hand Syndrome and Callosal Apraxia in Multiple Sclerosis: Implications for Interhemispheric Communication

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
A. Lunardelli ◽  
A. Sartori ◽  
P. Mengotti ◽  
R. I. Rumiati ◽  
V. Pesavento
Keyword(s):  
Multiple Sclerosis ◽  
Corpus Callosum ◽  
Specific Pattern ◽  
Task Demands ◽  
Fine Motor ◽  
Interhemispheric Communication ◽  
Left Hand ◽  
Alien Hand Syndrome ◽  
Motor Activities ◽  
Alien Hand

We report a case of a 47-year-old woman with 35-year history of multiple sclerosis, who showed alien hand signs, a rare behavioural disorder that involves unilateral goal-directed movements that are contrary to the individual's intention. Alien hand syndrome has been described in multiple sclerosis (MS) only occasionally and is generally suggestive of callosal disconnection. The patient presented also with bilateral limb apraxia and left hand agraphia, raising the possibility of cortical dysfunction or disconnection, in addition to corpus callosum and white matter involvement. Her specific pattern of symptoms supports the role of the corpus callosum in interhemispheric communication for complex as well as fine motor activities and may indicate that it can serve as both an inhibitory and excitatory function depending on task demands.

scholarly journals Case Report: Good Prognosis of Mixed Alien Hand Syndrome by Verbal-Cue Rehabilitation Exercise

2021 ◽  
Vol 12 ◽  
Author(s):  
Kang Qu ◽  
Lin Gan ◽  
Wei Jiang ◽  
Peng Yu ◽  
Ming Dong
Keyword(s):  
Corpus Callosum ◽  
Single Case ◽  
Good Prognosis ◽  
Hand Movements ◽  
Left Hand ◽  
Left Handed ◽  
Alien Hand Syndrome ◽  
Before And After ◽  
Alien Hand ◽  
The Right

Mixed alien hand syndrome is a rare disease reported in the literature. The mixed callosal–frontal variant of alien hand syndrome is associated with uncoordinated hand movements, and patients may present with an involuntary grasp reflex and intermanual conflict. There are few videos in the existing literature on the comparison of patients' condition before and after recovery of the symptoms of mixed alien hand syndrome. We presented the prognosis of mixed alien hand syndrome in the form of a video. In addition, we have included some videos on the comparison of the condition of patients before and after recovery of the symptoms of mixed alien hand syndrome. A 57-year-old woman presented with left-handed intermanual conflict and right-handed involuntary grasp reflex due to infarction of the frontal lobe and corpus callosum. She was diagnosed with a mixed callosal–frontal variant of alien hand syndrome. Her left hand counteracted the purposeful movements of the right hand. However, the intermanual conflict disappeared after 3 months of therapy, including drug treatment and verbal-cue rehabilitation, and she regained normal coordination of her hand movements. Her prognosis was good despite the large corpus callosum lesions. The uncoordinated hand movements of the patient affected her daily life and caused psychological problems. Initiating rehabilitation early was important and necessary for her to regain coordination. It is possible that the verbal-cue training method played an important role in the recovery of the patient. Therefore, this method of rehabilitation deserves consideration and can be adopted in larger cohort studies as we presented only a single case. The possible mechanisms behind the verbal-cue exercise require further studies, and this patient had a good prognosis despite severe corpus callosum injury, which may merit further investigation.

A case of the corpus callosum and alien hand syndrome from a discrete paracallosal lesion

Neurocase ◽  
2010 ◽  
Vol 16 (4) ◽  
pp. 281-285 ◽  
Author(s):  
Raymond Faber ◽  
Alvi Azad ◽  
Richard Reinsvold
Keyword(s):  
Corpus Callosum ◽  
Alien Hand Syndrome ◽  
Alien Hand

Alien hand syndrome: Interhemispheric motor disconnection due to a lesion in the midbody of the corpus callosum

Neurology ◽  
1995 ◽  
Vol 45 (4) ◽  
pp. 802-808 ◽  
Author(s):  
D. H. Geschwind ◽  
M. Iacoboni ◽  
M. S. Mega ◽  
D. W. Zaidel ◽  
T. Cloughesy ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Alien Hand Syndrome ◽  
Alien Hand

scholarly journals Alien hand and complex regional pain syndromes during rehabilitation program

2021 ◽  
Author(s):  
Beata Tarnacka ◽  
Paweł Turczyn
Keyword(s):  
Corticobasal Degeneration ◽  
Pain Syndrome ◽  
Rehabilitation Program ◽  
Type I ◽  
Elbow Fracture ◽  
Left Hand ◽  
Alien Hand Syndrome ◽  
Regional Pain Syndromes ◽  
Complex Regional Pain Syndromes ◽  
Alien Hand

Introduction: Alien hand syndrome (AHS) belongs to the group of asymmetrical movement symptoms that are a characteristic picture of neurodegenerative diseases such as corticobasal degeneration syndrome (CBS). Changes in the musculoskeletal system such as dystonia, bradykinesia and myoclonus may also occur in the subacute stage of complex regional pain syndrome (CRPS) type I. Aim: To learn about difficulties related to diagnosis and rehabilitation of a patient with AHS and CRPS type I complicated by an upper limb fracture. Case study: A case of a patient admitted to the rehabilitation department with compulsive unilateral involuntary groping and grasping movements of the left hand for about half a year is presented. The woman has been suspected of CBS. A few months after the diagnosis, the patient was admitted to the rehabilitation ward, where she suffered an elbow fracture during exercise. Two months after fracture, type I CRPS was diagnosed. Results and discussion: AHS in CBS and CRPS type I may have a similar clinical picture, which makes differentiation difficult. It is very rare that both diseases coexist with each other. They can also lead to a number of unwanted symptoms such as limb fractures. Conclusions: CRPS may increase the symptoms of dystonia due to other causes. Patients with AHS and dystonia are more likely to break because of rapid movements alone or because of immobilization and osteoporotic changes. As a result, treatment and rehabilitation cannot be based on a questionable diagnosis of a neurological syndrome.

scholarly journals Alien hand syndrome following corpus callosum infarction: A case report and review of the literature

2016 ◽  
Vol 12 (4) ◽  
pp. 2129-2135 ◽  
Author(s):  
Xiaoyu Gao ◽  
Bing Li ◽  
Wenzheng Chu ◽  
Xuwen Sun ◽  
Chunjuan Sun
Keyword(s):  
Case Report ◽  
Corpus Callosum ◽  
Review Of The Literature ◽  
Alien Hand Syndrome ◽  
Alien Hand

First-Episode ‘Coenesthetic’ Schizophrenia Presenting with Alien Hand Syndrome and Partial Agenesis of the Corpus Callosum

2008 ◽  
Vol 58 (3-4) ◽  
pp. 118-122 ◽  
Author(s):  
Andor Simon ◽  
Mark Walterfang ◽  
Carlo Petralli ◽  
Dennis Velakoulis
Keyword(s):  
Corpus Callosum ◽  
First Episode ◽  
Alien Hand Syndrome ◽  
Alien Hand

scholarly journals Alien hand syndrome in a patient with corpus callosum ischemia associated with MTHFR mutation

2015 ◽  
Vol 357 ◽  
pp. e414
Author(s):  
A. Cetiz ◽  
S. Tasdemir ◽  
O. Oz ◽  
H. Akgun ◽  
S. Hamcan ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Alien Hand Syndrome ◽  
Alien Hand ◽  
Mthfr Mutation

Recurrent Alien Hand Syndrome in a Multiple Sclerosis Case

2008 ◽  
Vol 14 (5) ◽  
pp. 316-317 ◽  
Author(s):  
Asl Kurne ◽  
Gul Yalcin Cakmakli ◽  
Rana Karabudak
Keyword(s):  
Multiple Sclerosis ◽  
Multiple Sclerosis Case ◽  
Alien Hand Syndrome ◽  
Alien Hand

scholarly journals Involuntary hand levitation associated with parietal damage: another alien hand syndrome

2001 ◽  
Vol 59 (3A) ◽  
pp. 521-525 ◽  
Author(s):  
Paulo E.M. Carrilho ◽  
Paulo Caramelli ◽  
Francisco Cardoso ◽  
Egberto Reis Barbosa ◽  
Carlos A. Buchpiguel ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Corpus Callosum ◽  
Motor Activity ◽  
Parietal Lobe ◽  
Frontal Lobes ◽  
Motor Behaviour ◽  
Alien Hand Syndrome ◽  
Alien Hand ◽  
Visual Clues

The alien hand syndrome (AHS) usually consists of an autonomous motor activity perceived as an involuntary and purposeful movement, with a feeling of foreignness of the involved limb, commonly associated with a failure to recognise ownership of the limb in the absence of visual clues. It has been described in association to lesions of the frontal lobes and corpus callosum. However, parietal damage can promote an involuntary, but purposeless, hand levitation, which, sometimes, resembles AHS. In the present study, four patients (cortico-basal ganglionic degeneration -- n=2; Alzheimer's disease -- n=1 and parietal stroke -- n=1) who developed alien hand motor behaviour and whose CT, MRI and/or SPECT have disclosed a major contralateral parietal damage or dysfunction are described. These results reinforce the idea that parietal lobe lesions may also play a role in some patients with purposeless involuntary limb levitation, which is different from the classic forms of AHS.

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