scholarly journals Erratum to “Effectiveness of the Novel Herbal Medicine, KIOM-MA, and Its Bioconversion Product, KIOM-MA128, on the Treatment of Atopic Dermatitis”

2014 ◽  
Vol 2014 ◽  
pp. 1-1
Author(s):  
Tae Ho Chung ◽  
Tae Jin Kang ◽  
Won-Kyung Cho ◽  
Ga Yeong Im ◽  
Geum Seon Lee ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Herbal Medicine ◽  
The Novel

scholarly journals Effectiveness of the Novel Herbal Medicine, KIOM-MA, and Its Bioconversion Product, KIOM-MA128, on the Treatment of Atopic Dermatitis

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Tae Ho Chung ◽  
Tae Jin Kang ◽  
Won-Kyung Cho ◽  
Ga Young Im ◽  
Geum Seon Lee ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Herbal Medicine ◽  
Oral Administration ◽  
Aluminum Hydroxide ◽  
Lactobacillus Acidophilus ◽  
Hplc Analysis ◽  
Clinical Signs ◽  
The Novel ◽  
Fermented Product ◽  
Therapeutic Properties

This study was conducted to determine if oral administration of the novel herbal medicine, KIOM-MA, and itsLactobacillus acidophilus-fermented product, KIOM-MA128, has therapeutic properties for the treatment of atopic dermatitis (AD). Using AD-induced BALB/c mice by Ovalbumin and aluminum hydroxide, the effectiveness of KIOM-MA and KIOM-MA128 on AD was evaluated. Oral administration of KIOM-MA and KIOM-MA128 reduced major clinical signs of AD including erythema/darkening, edema/papulation, excoriations, lichenification/prurigo, and dryness. Interestingly, KIOM-MA128 more significantly improved AD-related symptoms including decrease of IgE level in the plasma as well as reduction of scratching behavior, skin severity in the AD BALB/c model. HPLC analysis showed the significant changes in the constituent patterns between KIOM-MA and KIOM-MA128. Our results suggest that both KIOM-MA and KIOM-MA128 have potential for therapeutic reagent for the treatment of AD, and further, the efficacy is significantly enhanced byL. acidophilusfermentation via increases in its indicator molecule.

Treatment of atopic dermatitis with Chinese herbal medicine. Therapeutic effects of Hochuekkitou.

1989 ◽  
Vol 51 (5) ◽  
pp. 1003-1013 ◽  
Author(s):  
Hiromi KOBAYASHI ◽  
Masamitsu ISHII ◽  
Tsukasa TANII ◽  
Takeshi KOHNO ◽  
Toshio HAMADA
Keyword(s):  
Atopic Dermatitis ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Therapeutic Effects ◽  
Chinese Herbal

scholarly journals An Alternative Approach to Atopic Dermatitis: Part I—Case-Series Presentation

2004 ◽  
Vol 1 (1) ◽  
pp. 49-62 ◽  
Author(s):  
Hiromi Kobayashi ◽  
Kuniaki Takahashi ◽  
Nobuyuki Mizuno ◽  
Haruo Kutsuna ◽  
Masamitsu Ishii
Keyword(s):  
Atopic Dermatitis ◽  
Herbal Medicine ◽  
Conventional Therapy ◽  
Complex Disease ◽  
Case Series ◽  
Line Treatment ◽  
Second Line ◽  
Substantial Portion ◽  
Alternative Approach ◽  
Evidential Basis

Atopic dermatitis (AD) is a complex disease of obscure pathogenesis. A substantial portion of AD patients treated with conventional therapy become intractable after several cycles of recurrence. Over the last 20 years we have developed an alternative approach to treat many of these patients by diet and Kampo herbal medicine. However, as our approach is highly individualized and the Kampo formulae sometimes complicated, it is not easy to provide evidence to establish usefulness of this approach. In this Review, to demonstrate the effectiveness of the method of individualized Kampo therapy, results are presented for a series of patients who had failed with conventional therapy but were treated afterwards in our institution. Based on these data, we contend that there exist a definite subgroup of AD patients in whom conventional therapy fails, but the ‘Diet and Kampo’ approach succeeds, to heal. Therefore, this approach should be considered seriously as a second-line treatment for AD patients. In the Discussion, we review the evidential status of the current conventional strategies for AD treatment in general, and then specifically discuss the possibility of integrating Kampo regimens into it, taking our case-series presented here as evidential basis. We emphasize that Kampo therapy for AD is more ‘art’ than technology, for which expertise is an essential pre-requisite.

scholarly journals Evaluation of Itch by Using NC/NgaTnd Mice: A Model of Human Atopic Dermatitis

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Akane Tanaka ◽  
Hiroshi Matsuda
Keyword(s):  
Animal Model ◽  
Atopic Dermatitis ◽  
Clinical Symptoms ◽  
Skin Barrier ◽  
Sensory Nerves ◽  
Laboratory Animals ◽  
Skin Barrier Function ◽  
The Novel ◽  
Suitable Animal Model ◽  
Spontaneous Animal Model

Atopic dermatitis (AD) is the extremely complicated syndrome that various abnormalities develop in a heap. There are various factors in patients for the onset and exacerbation of AD, including genetic cofactors of individuals, environmental factors, the failure of the skin barrier function, unfavorable regulation of the immune system, and the hypersensitivity of sensory nerves. In recent years, there have been many trials of the drug discovery that targets itch, because itch is one of the most serious clinical symptoms of AD. The selection of the suitable animal model that represents the condition of patients, as well as innovative analyzing protocols that can precisely evaluate itch, is indispensable for investigation of an effective drug for AD. In the paper, the unique spontaneous animal model for AD (NC/NgaTnd mice) and the novel quantification system of the laboratory animals that may bring a great progress in the future study of itch are outlined.

scholarly journals Correlation between ginseng radix and the novel coronavirus about a possible future alternative treatment

2020 ◽  
Vol 9 (8) ◽  
pp. e712985720
Author(s):  
Anne Karynne da Silva Barbosa ◽  
Wenna Lúcia Lima
Keyword(s):  
Clinical Practice ◽  
Herbal Medicine ◽  
Respiratory Tract ◽  
Alternative Treatment ◽  
Herbal Medicines ◽  
The Novel ◽  
Wuhan City ◽  
Radix Ginseng ◽  
First Millennium ◽  
Novel Coronavirus

In 2019 in Wuhan city (China), is was outbreak about a novel coronavirus, causes an infections respirator, in children and adults, and is new condition was call for COVID-19. The present study being about herbal medicines and their correlation with diseases on respiratory tract basically COVID-19. To date, there are no studies showing how Ginseng Radix cooperated with the prevention or for to treat coronavirus diseases, so the aimed the present study was a to analyze in literature about this. The aim is to observe the correlation about the Ginseng Radix as a future treatment in novel coronavirus. The present study is a fruit of a review integrative of literature, where the keywords was search in databases Pubmed and Scielo.org, the keywords (Herbal medicines, Ginseng radix and Coronavirus infections) are presents in DeCS. The herbal medicines are famous alternative therapeutic for the treatment a most diseases, when used the herbal medicines for various diseases, being diseases cardiology, immunology, and too tract respiratory. The use for the herbal medicines is a secular practice, and we found a most popular, but is present study is about the ginseng radix. Ginseng is an herbal medicine derived from the root of the panax, and your use is described since the first millennium, your properties are preventing many diseases, including cancer, hypertension, and others, described in the literature. The Ginseng radix is an herbal medicine be used in the treatment for the children and adults, the problems for the tract respiratory, and exists a guideline specific for the herbal medicines and the use in clinical practice.

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