scholarly journals The Impact of Low Muscle Mass Definition on the Prevalence of Sarcopenia in Older Australians

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Solomon Yu ◽  
Sarah Appleton ◽  
Robert Adams ◽  
Ian Chapman ◽  
Gary Wittert ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Older People ◽  
Muscle Mass ◽  
Muscle Function ◽  
Reference Population ◽  
Skeletal Mass ◽  
The Impact ◽  
Gender Specific ◽  
Linear Regressions ◽  
Mass Definition

Background.Sarcopenia is the presence of low muscle mass and low muscle function. The aim of this study was to establish cutoffs for low muscle mass using three published methods and to compare the prevalence of sarcopenia in older Australians.Methods.Gender specific cutoffs levels were identified for low muscle mass using three different methods. Low grip strength was determined using established cutoffs of <30 kg for men and <20 kg for women to estimate the prevalence of sarcopenia.Results.Gender specific cutoffs levels for low muscle mass identified were (a) <6.89 kg/m2for men and <4.32 kg/m2for women, <2 standard deviation (SD) of a young reference population; (b) <7.36 kg/m2for men and <5.81 kg/m2for women from the lowest 20% percentile of the older group; and (c) <−2.15 for men and <−1.42 for women from the lowest 20% of the residuals of linear regressions of appendicular skeletal mass, adjusted for fat mass and height. Prevalence of sarcopenia in older (65 years and older) people by these three methods for men was 2.5%, 6.2%, and 6.4% and for women 0.3%, 9.3%, and 8.5%, respectively.Conclusions.Sarcopenia is common but consensus on the best method to confirm low muscle mass is required.

scholarly journals Differences in body composition and grip between Japanese and Thai older people living in Thailand

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
T Yoda ◽  
B Saengrut ◽  
R Rattanasathien ◽  
Y Ishimoto ◽  
T Saito ◽  
...  
Keyword(s):  
Body Composition ◽  
Standard Deviation ◽  
Older People ◽  
Grip Strength ◽  
Ethnic Group ◽  
Muscle Mass ◽  
Body Fat ◽  
Chiang Mai ◽  
Chiang Mai Province ◽  
Muscle Mass Loss

Abstract Background Age-related muscle mass loss is one of the main risk factors for osteoporosis and fractures among older people. Thus, prevention of muscle mass loss in older people is an important issue. We examined ethnic group-related differences in body composition and grip strength among older people living in the same area. Methods We measured body composition and grip strength among local Thai older people living in Chiang Mai Province, as well as in Japanese older people who emigrated to Chiang Mai Province in their retirement. A self-reported questionnaire regarding socio-demographic status was also administered. Measurement items were averaged and compared by sex and ethnic group. Questionnaire items were also categorized by sex and ethnic group. Results A total of 119 older people participated, including 47 Japanese participants (26 men, 21 women) and 72 Thai participants (16 men, 56 women). The average age of Japanese participants was 71.1 years (standard deviation: 4.89), and the average age of Thai participants was 68.8 years (standard deviation: 5.61). Significant differences between ethnic groups were found in percentage of body fat in women (Japanese average: 32.9% vs. Thai average: 37.6%, p &lt; 0.05), skeletal muscle mass index (SMI) in men (Japanese average: 7.85 kg/m2 vs. Thai average: 7.31 kg/m2, p &lt; 0.05) and average grip strength in men (Japanese: 35.1 kg vs. Thai: 30.7 kg, p &lt; 0.05). Conclusions Our preliminary results suggest that Thai older people, particularly men, are weaker than Japanese older people. Decreased muscle mass is directly responsible for functional impairment, involving loss of strength, increased likelihood of falls, and loss of autonomy. Preventing muscle weakness among older people is important. In future studies, we plan to analyze and clarify the differences between Thai and Japanese older people to identify effective methods to prevent muscle mass decreases. Key messages There were significant differences in average % body fat between older Japanese and Thai women. There were significant differences in average SMI and grip strength between older Japanese and Thai men.

scholarly journals Assessment of sarcopenia in patients with fibromyalgia

2021 ◽  
Author(s):  
Abeline Kapuczinski ◽  
Muhammad S. Soyfoo ◽  
Sandra De Breucker ◽  
Joëlle Margaux
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
Older People ◽  
Muscle Mass ◽  
Physical Performance ◽  
Muscle Function ◽  
Skeletal Muscle Mass ◽  
Fibromyalgia Impact Questionnaire ◽  
Control Group ◽  
European Working

AbstractFibromyalgia is a chronic disorder characterized by persistent widespread musculoskeletal pain. Patients with fibromyalgia have reduced physical activity and increased sedentary rate. The age-associated reduction of skeletal muscle mass and function is called sarcopenia. The European Working Group on Sarcopenia in Older People developed a practical clinical definition and consensus diagnostic criteria for sarcopenia. Loss of muscle function is common in fibromyalgia and in the elderly. The goal of this study is to determine whether the reduction of muscle function in fibromyalgia is related to sarcopenia according to the European Working Group on Sarcopenia in Older People criteria. Forty-five patients with fibromyalgia and thirty-nine healthy control female subjects were included. All the participants were assessed by Fibromyalgia Impact Questionnaire and SARC-F questionnaire. Muscle mass was evaluated by bioimpedance analysis, muscle strength by handgrip strength test and physical performance with the Short Physical Performance Battery. Fibromyalgia Impact Questionnaire and SARC-F scores were statistically significantly higher in the fibromyalgia group than in the control group, showing severe disease and a higher risk of sarcopenia in the fibromyalgia group (p < 0.001). Muscle strength and physical performance were statistically significantly lower in the group with fibromyalgia than in the control group (p < 0.001). There was no statistical difference between fibromyalgia and control groups regarding skeletal muscle mass (p = 0.263). Our study demonstrated a significant reduction in muscle function in fibromyalgia patients without any loss of muscle mass. Loss of muscle function without decrease in muscle mass is called dynapenia.

scholarly journals The impact of muscle function, muscle mass and sarcopenia on independent ageing in very old Swedish men

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kristin Franzon ◽  
Björn Zethelius ◽  
Tommy Cederholm ◽  
Lena Kilander
Keyword(s):  
Muscle Mass ◽  
Muscle Function ◽  
Very Old ◽  
Old Swedish ◽  
The Impact

scholarly journals Clinical Implications of Estimating Glomerular Filtration Rate with Three Different Equations among Older People. Preliminary Results of the Project “Screening for Chronic Kidney Disease among Older People across Europe (SCOPE)”

2020 ◽  
Vol 9 (2) ◽  
pp. 294 ◽  
Author(s):  
Andrea Corsonello ◽  
Regina Roller-Wirnsberger ◽  
Gerhard Wirnsberger ◽  
Johan Ärnlöv ◽  
Axel C. Carlsson ◽  
...  
Keyword(s):  
Older People ◽  
Muscle Mass ◽  
Limits Of Agreement ◽  
Multicenter Observational Study ◽  
Ckd Stage ◽  
Stage Classification ◽  
The Difference ◽  
Project Screening ◽  
The Impact ◽  
Κ Statistic

We aimed at investigating to what extent CKD may be staged interchangeably by three different eGFR equations in older people, and evaluating the source of discrepancies among equations in a population of 2257 patients older than 75 years enrolled in a multicenter observational study. eGFR was calculated by CKD-EPI, BIS and FAS equations. Statistical analysis was carried out by Bland–Altman analysis. κ statistic was used to quantify the agreement between equations in classifying CKD stages. The impact of selected variables on the difference among equations was graphically explored. The average difference between BIS and FAS was −0.24 (95% limits of agreement (95%LA = −4.64–4.14) mL/min/1.73 m2. The difference between CKD-EPI and BIS and between CKD-EPI and FAS was 8.97 (95%LA = −2.90–20.84) and 8.72 (95%LA = −2.11–19.56) mL/min/1.73 m2, respectively. As regards CKD stage classification, κ value was 0.47 for both CKD-EPI vs. FAS and CKD-EPI vs. BIS, while BIS and FAS had similar classificatory properties (κ = 0.90). Muscle mass was found related to the difference between CKD-EPI and BIS (R2 = 0.11) or FAS (R2 = 0.14), but not to the difference between BIS and FAS. In conclusion, CKD-EPI and BIS/FAS equations are not interchangeable to assess eGFR among older people. Muscle mass may represent a relevant source of discrepancy among eGFR equations.

DETERMINING THE CUT-OFF VALUES FOR SARCOPENIA IN THE KOREAN ELDERLY POPULATION USING BIOIMPEDANCE ANALYSIS

2015 ◽  
pp. 1-7
Author(s):  
E.-J. CHANG ◽  
H.-W. JUNG ◽  
S.-W. KIM ◽  
N.-J. HEO ◽  
H.-J. CHIN ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Elderly Population ◽  
Reference Group ◽  
Class Ii ◽  
Korean Population ◽  
Class I ◽  
Bioimpedance Analysis ◽  
Skeletal Mass ◽  
Korean Elderly ◽  
Gender Specific

Background: Bioimpedance analysis (BIA) is known to be a useful method for assessing sarcopenia because cost-effective and not involving radiation exposure. However, the cut-off values for sarcopenia using BIA have not yet been determined in the Korean population. Objectives: To establish the cut-off values for sarcopenia in the Korean elderly population with the use of BIA. Methods: Body composition assessed by BIA was obtained in 7,641 participants aged 20–34 years and 3,902 participants aged ≥65 years from data routinely collected during health examinations at Seoul National University Gangnam Center. Appendicular skeletal muscle mass was adjusted for height and weight. Gender-specific cut-points for class I and class II sarcopenia were defined as 1 and 2 standard deviations below the mean in the reference group aged 20–34 years, respectively. In addition, the gender-specific, lowest 20th percentile cut-offs for muscle mass in participants aged ≥65 years were determined. Results: The cut-offs for class I and class II sarcopenia in men for height-adjusted appendicular skeletal mass were 6.74 kg/m2 and 5.96 kg/m2 and for weight-adjusted appendicular skeletal mass were 29.4% and 27.4%, respectively; those in women for height-adjusted appendicular skeletal mass were 4.93 kg/m2 and 4.35 kg/m2, and for weight-adjusted appendicular skeletal mass were 25.6% and 23.9%, respectively. The lowest 20th percentile cut-offs for height-adjusted and weight-adjusted appendicular skeletal mass were 6.69 kg/m2 and 28.9% in men, and 5.76 kg/m2 and 24.5% in women, respectively. Based on the derived cut-offs, prevalence of class II sarcopenia in participants ≥65 years of age for height-adjusted and weight-adjusted appendicular skeletal mass was 3.7% and 3.5% in men, and 0.2% and 11.2% in women, respectively. Among the above-mentioned definitions, sarcopenia by height-adjusted appendicular skeletal mass was significantly associated with 2-year mortality in older participants. Conclusions: Muscle mass deficit in the Korean population can be assessed based on the cut-offs determined in this study using BIA.

scholarly journals Hyperhomocysteinemia Associated with Low Muscle Mass, Muscle Function in Elderly Hemodialysis Patients: An Analysis of Multiple Dialysis Centers

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Chi-Sin Wang ◽  
Te-Chih Wong ◽  
Tuyen Van Duong ◽  
Chien-Tien Su ◽  
Hsi-Hsien Chen ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Muscle Mass ◽  
Muscle Function ◽  
Stepwise Regression ◽  
Handgrip Strength ◽  
Hemodialysis Patients ◽  
Stepwise Regression Analysis ◽  
Muscle Quality ◽  
The Impact ◽  
Elderly Hemodialysis Patients

Background. The hyperhomocysteinemia was with high prevalence and has been considered as a risk factor for cardiovascular disease in hemodialysis patients. These patients also experienced a high risk of muscle wasting caused by the comorbidity, malnutrition, and low physical activity. We investigated the associations of homocysteinemia with muscle mass, muscle function in elderly hemodialysis patients. Methods. A clinical cross-sectional study was conducted on 138 hemodialysis patients aged 65 years and above in seven hospital-based hemodialysis centers in Taiwan. The data on anthropometry, laboratory, and 3-day dietary intake was examined. The skeletal muscle mass (SMM) was measured by the bioelectrical impedance analysis; the SMM was adjusted by height or weight as SMMHt2 (kg/m2) and SMMWt (%). Muscle function was defined as handgrip strength (HGS) (kg) measured by handgrip dynamometer. Statistical analyses were conducted using simple regression and multivariable stepwise regression analysis. Results. In the total sample, 74.6 % of hemodialysis patients were hyperhomocysteinemia (≥ 15 μmol/L). The means of SMMHt2, SMMWt, arm lean mass, hand grip strength, and muscle quality were 8.7 ± 1.2, 37.7 ± 5.6, 1.7 ± 0.5, 21.1 ± 7.4, and 10.0 ± 3.0, respectively. The multivariable stepwise regression analysis showed that homocysteinemia level was significantly inversely associated with SMMWt (B-coeff. = -0.03, p = 0.02) in hemodialysis patients above 65 years old, but not with muscle function. Conclusions. Hyperhomocysteinemia is common and associated with decreased muscle mass in the elderly hemodialysis patients. Future studies are suggested to explore the impact of the homocysteine-lowering therapy on muscle decline.

Gender specific paediatric reference data for muscle function parameters assessed using jumping mechanography

2019 ◽  
Author(s):  
Sonal Palande ◽  
Veena Ekbote ◽  
Shashi Chiplonkar ◽  
Raja Padidela ◽  
Zulf Mughal ◽  
...  
Keyword(s):  
Muscle Function ◽  
Reference Data ◽  
Jumping Mechanography ◽  
Gender Specific
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