scholarly journals Sleep, Muscle Mass and Muscle Function in Older People: A Cross-Sectional Analysis Based on Data From the Berlin Aging Study II (BASE-II)

2016 ◽  
Author(s):  
Nikolaus Buchmann ◽  
Dominik Spira ◽  
Kristina Norman ◽  
Ilja Demuth ◽  
Rahel Eckardt ◽  
...  
Keyword(s):  
Older People ◽  
Muscle Mass ◽  
Muscle Function ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Aging Study ◽  
Sectional Analysis

scholarly journals Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis

2020 ◽  
Author(s):  
Emma L Watson ◽  
Thomas J Wilkinson ◽  
Tom F O’Sullivan ◽  
Luke A Baker ◽  
Douglas W Gould ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Exercise Capacity ◽  
Muscle Mass ◽  
Ex Vivo ◽  
Muscle Size ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

AbstractEvidence is growing for a role of vitamin D in regulating skeletal muscle mass, strength and functional capacity. Given the role the kidneys play in activating total vitamin D, and the high prevalence of vitamin D deficiency in Chronic Kidney Disease (CKD), it is possible that deficiency contributes to the low levels of physical function and muscle mass in these patients. This is a secondary cross-sectional analysis of previously published interventional study, with ex vivo follow up work. 34 CKD patients at stages G3b-5 (eGFR 25.5 ± 8.3ml/min/1.73m2; age 61 ± 12 years) were recruited, with a sub-group (n=20) also donating a muscle biopsy. Vitamin D and associated metabolites were analysed in plasma by liquid chromatography tandem-mass spectroscopy and correlated to a range of physiological tests of muscle size, function, exercise capacity and body composition. The effects of 1α,25(OH)2D3 supplementation on myogenesis and myotube size was investigated in primary skeletal muscle cells from vitamin D deficient donors. In vivo, there was no association between total or active vitamin D and muscle size or strength, but a significant correlation with was seen with the total form. Ex vivo, 1α,25(OH)2D3 supplementation reduced IL-6 mRNA expression, but had no effect upon proliferation, differentiation or myotube diameter. This early preliminary work suggests that vitamin D deficiency is not a prominent factor driving the loss of muscle mass in CKD, but may play a role in reduced exercise capacity.

scholarly journals Association Between Renal Function and Cognitive Ability Domains in the Einstein Aging Study: A Cross-Sectional Analysis

2014 ◽  
Vol 70 (6) ◽  
pp. 764-770 ◽  
Author(s):  
Andrea R. Zammit ◽  
Mindy J. Katz ◽  
Jennifer Y. Lai ◽  
Molly E. Zimmerman ◽  
Markus Bitzer ◽  
...  
Keyword(s):  
Renal Function ◽  
Cognitive Ability ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Aging Study ◽  
Sectional Analysis

Dietary vitamin D intake and muscle mass in older women. Results from a cross-sectional analysis of the EPIDOS study

2012 ◽  
Vol 17 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Charlotte Dupuy ◽  
V. Lauwers-Cances ◽  
G. Abellan Van Kan ◽  
S. Gillette ◽  
A. -M. Schott ◽  
...  
Keyword(s):  
Vitamin D ◽  
Older Women ◽  
Muscle Mass ◽  
Dietary Vitamin ◽  
Cross Sectional ◽  
Vitamin D Intake ◽  
Cross Sectional Analysis ◽  
Sectional Analysis ◽  
Dietary Vitamin D
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